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Ching-yi Chang

Associate Research Professor of Pharmacology and Cancer Biology
Pharmacology & Cancer Biology
Box 103057, Durham, NC 27710
Medical Science Res Bldg III, 3 Genome Court, Durham, NC 27710

Selected Grants


Manipulating normal estrogen physiology as a therapeutic approach in cancer

ResearchAssociate Research Professor · Awarded by National Institutes of Health · 2023 - 2028

NK cell response as a clinical differentiator of endocrine therapies

ResearchAssociate Research Professor · Awarded by Department of Defense · 2024 - 2027

Targeting the GRHL2/AGR2/LYPD3 axis in breast cancer

ResearchAssociate Research Professor · Awarded by Susan G. Komen Breast Cancer Foundation · 2018 - 2024

Cancer cell intrinsic and extrinsic actions of steroid hormones in breast tumors

ResearchAssistant Research Professor · Awarded by Department of Defense · 2018 - 2023

Optimization of ERalpa-LBD-based CAR-T switch

ResearchAssistant Research Professor · Awarded by Cell Design Labs, Inc · 2017 - 2018

Manipulating normal estrogen physiology as a therapeutic approach in cancer

ResearchAssociate Research Professor · Awarded by National Institutes of Health · 2023 - 2028

NK cell response as a clinical differentiator of endocrine therapies

ResearchAssociate Research Professor · Awarded by Department of Defense · 2024 - 2027

Targeting the GRHL2/AGR2/LYPD3 axis in breast cancer

ResearchAssociate Research Professor · Awarded by Susan G. Komen Breast Cancer Foundation · 2018 - 2024

Cancer cell intrinsic and extrinsic actions of steroid hormones in breast tumors

ResearchAssistant Research Professor · Awarded by Department of Defense · 2018 - 2023

Optimization of ERalpa-LBD-based CAR-T switch

ResearchAssistant Research Professor · Awarded by Cell Design Labs, Inc · 2017 - 2018

The role of ERRalpha/PGC-1 in disease pathogenesis

ResearchAssistant Research Professor · Awarded by National Institutes of Health · 2006 - 2018

Mechanism-informed combination strategies targeting metabolism in prostate cancer

ResearchPrincipal Investigator · Awarded by Department of Defense · 2015 - 2016

The Androgen Receptor: Cofactor Interface

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2002 - 2005

Fellowships, Gifts, and Supported Research


Core Facility Voucher · 2015 - 2016 Principle Investigator · Duke University Cancer Institure · $10,000.00 Development and validation of hormone receptor-positive breast and prostate cancer bone metastasis models
Postdoctoral Fellowship · 1999 - 2002 Principle Investigator · Department of Defense · $126,000.00
Advanced Pre-doctoral Fellowship · 1996 - 1997 Principle Investigator · PhRMA · $25,000.00

External Relationships


  • General Dynamics Information Technology
  • Sermonix Pharmaceuticals

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.