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David Manfield Brizel

Leonard Prosnitz Distinguished Professor of Radiation Oncology
Radiation Oncology
Box 3085 Med Ctr, Durham, NC 27710
05135 Morris Bldg, Durham, NC 27710

Selected Grants


Computational tumor phenotyping to interrogate treatment resistance and immune dysregulation in head and neck cancer

ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2029

BMX-001 as a Radio-Protector in Head and Neck Cancer Therapy Phase I and Phase II

ResearchPrincipal Investigator · Awarded by BioMimetix Pharmaceutical, Inc. · 2017 - 2022

Patient Reported Outcomes and Financial Toxicity in Head and Neck Cancer

ResearchMentor · Awarded by Radiation Oncology Institute · 2018 - 2022

NCI National Clinical Trials Network U10 (Year 5)

Clinical TrialCo-Principal Investigator · Awarded by National Institutes of Health · 2014 - 2019

Digital tomosynthesis: a new paradigm for radiation treatment verification

ResearchCollaborator · Awarded by National Institutes of Health · 2007 - 2009

Measurement of Hypoxia in Non-Small Cell Lung Carcinoma

ResearchInvestigator · Awarded by National Institutes of Health · 2002 - 2006

Hyperglycemia and Oxygen Breathing in Head & Neck Cancer

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2000 - 2004

Predicting Human Tumor Response by 31p MRS

ResearchCo Investigator · Awarded by National Institutes of Health · 1995 - 2001

Hyperthermia And Perfusion Effects In Cancer Therapy

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1997 - 1999

Hyperthermia And Perfusion Effects In Cancer Therapy

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1995 - 1999

Hyperthermia And Perfusion Effects In Cancer Therapy

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1987 - 1999

Heat & Radiation Effects On Tumor Microcirculation

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1997 - 1999

Effects Of Heat And Radiation On Tumor

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1996 - 1999

Hyperthermia And Perfusion Effects In Cancer Therapy

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1993 - 1995

External Relationships


  • BioMimetix JVLLC
  • UpToDate, Inc
  • WCG ACI Clinical

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.