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Dawn Elizabeth Bowles

Assistant Professor in Surgery
Surgery, Surgical Sciences
Box 2642 Med Ctr, Durham, NC 27710
421B MSRB, Durham, NC 27710

Selected Grants


Tolerance to Allogeneic Hearts via Implantation of Cultured Donor Thymus

ResearchCo Investigator · Awarded by National Institutes of Health · 2025 - 2028

Stimulating Access to Research in Residency (StARR) - NHLBI

Inst. Training Prgm or CMEPreceptor · Awarded by National Heart, Lung, and Blood Institute · 2018 - 2028

Persistent Injury Activated EC in Fibrosis

FellowshipCollaborator · Awarded by American Heart Association · 2026 - 2027

Leveraging Drosophila to identify novel and conserved regulators of cardiomyocyte polyploidy

ResearchAdvisor · Awarded by National Institutes of Health · 2025 - 2027

Genetic engineering of kidney allografts by ex vivo perfusion delivery of adeno-associated viral vectors

ResearchCo Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2027

Promoting Cardiac Allograft Tolerance with PD-L1 Gene Therapy in a Preclinical Porcine Model

ResearchPrincipal Investigator · Awarded by American Heart Association · 2026 - 2026

A Multi-omics and Multi-Species Examination of Combined Environmental Stressors of Space Exploration

ResearchPrincipal Investigator · Awarded by National Aeronautics and Space Administration · 2021 - 2026

Inducing Xenotolerance via Chimeric Thymus

ResearchInvestigator · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2026

Characterization of end-stage heart failure

ResearchPrincipal Investigator · Awarded by Bayer Aktiengesellschaft (same as Bayer AG) · 2024 - 2026

Transplantation of Cryopreserved Thymus

ResearchCo Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2023 - 2026

Gene Therapy for Cardiac Transplantation

ResearchPrincipal Investigator · Awarded by Solid Biosciences · 2023 - 2025

Improving Cardiac Transplant Outcomes Through PD-L1 Overexpression Gene Therapy

FellowshipCo-Principal Investigator · Awarded by Thoracic Surgery Foundation for Research and Education · 2023 - 2025

Fortilin, CTNNA3, and the Heart

ResearchPrincipal Investigator · Awarded by University of Washington · 2021 - 2025

Improving Cardiac Transplant Outcomes Through PD-L1 Overexpression Gene Therapy

FellowshipPrincipal Investigator · Awarded by American Heart Association · 2023 - 2024

Turek - Step 2 Project

ResearchCo Investigator · Awarded by Enzyvant · 2022 - 2023

Right Ventricular Metabolic Dysregulation after Surgery for Heart Failure

ResearchAdvisor · Awarded by International Anesthesia Research Society · 2021 - 2023

Development of a lightweight, portable, pneumatic drive unit for long-term counterpulsation support

ResearchCo Investigator · Awarded by NuPulseCV, Inc. · 2019 - 2022

Awakening Endogenous Retroviruses with the Space Environment

ResearchPrincipal Investigator · Awarded by National Aeronautics and Space Administration · 2019 - 2022

Proteomic Signatures of Space Radiation Induced Cardiovascular Degeneration

ResearchPrincipal Investigator · Awarded by National Aeronautics and Space Administration · 2016 - 2022

Radiation Resistance Conferred by Small Proline Rich Proteins (SPRRs)

ResearchPrincipal Investigator · Awarded by National Aeronautics and Space Administration · 2021 - 2022

Enzyvant Monkey Study

ResearchCo Investigator · Awarded by Enzyvant · 2019 - 2022

Gene Therapy Countermeasure for Detrimental Effects of Space Radiation

ResearchPrincipal Investigator · Awarded by Baylor College of Medicine · 2019 - 2021

Stratification of heart failure patients for cardiac recovery upon cardiac unloading by left Ventricular assist device therapy

ResearchPrincipal Investigator · Awarded by Humanitas Mirasole S.p.a · 2020 - 2021

Evolving Inside the Box

FellowshipPrincipal Investigator · Awarded by North Carolina Biotechnology Center · 2018 - 2020

Heart Cap Implants

ResearchPrincipal Investigator · Awarded by North Carolina State University · 2019 - 2020

Utilization of Two Heartmate III Pumps as a Total Artificial Heart Replacement

ResearchCo-Principal Investigator · Awarded by St. Jude Medical Inc. · 2017 - 2019

Expanding the capabilities and the utilization of the Duke Human Heart Repository

EquipmentPrincipal Investigator · Awarded by North Carolina Biotechnology Center · 2017 - 2019

Cadaver Implant Studies of PABP

ResearchPrincipal Investigator · Awarded by 3R Life Sciences Taiwan Ltd. · 2018 - 2019

Protection from cardiac ischemic injury through use of KP544

ResearchPrincipal Investigator · Awarded by Krenitsky Pharmaceuticals Inc. · 2017 - 2018

E3 Ligases and Deubiquitinases in GPCR Down Regulation

ResearchResearcher · Awarded by National Institutes of Health · 2005 - 2016

Heart Risk Model

ResearchPrincipal Investigator · Awarded by National Aeronautics and Space Administration · 2013 - 2016

Expanding the Donor Pool for Heart Transplantation

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2012 - 2014

Proteomic Profiling of Human Heart Tissue Exposed to Microgravity

ResearchPrincipal Investigator · Awarded by National Aeronautics and Space Administration · 2012 - 2013

Peripheral endothelial and muscle cell pathology in cardiovascular disease

ResearchCollaborator · Awarded by National Institutes of Health · 2010 - 2013

Autologous EPC lining to improve biocompatibility of circulatory assist devices

ResearchInvestigator · Awarded by National Institutes of Health · 2009 - 2012

PTEN Gene Therapy for Vein Graft Disease

ResearchInvestigator · Awarded by National Institutes of Health · 2009 - 2012

Myocardial Gene Transfer during Cardiac Surgery in Swine

ResearchCo Investigator · Awarded by National Institutes of Health · 2003 - 2008

External Relationships


  • AskBio (owned by Bayer)
  • Bayer
  • Caripae Bio LLC
  • Regeneron Pharmaceuticals
  • Solid Biosciences

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.