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Dennis Ko
Associate Professor in Molecular Genetics and Microbiology
Molecular Genetics and Microbiology
dennis.ko@duke.edu
0049 CARL Building, Box 3053, 213 Research Drive, Durham, NC 27710
Research
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At a Glance
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Credentials
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Research
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Publications
Selected Publications
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Advising & Mentoring
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Selected Grants
Tri-Institutional Molecular Mycology and Pathogenesis Training Program
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
2024 - 2029
Targeting Hepatocyte Senescence to Improve NAFLD
Research
Advisor ·
Awarded by National Institutes of Health ·
2024 - 2029
Genetic Contributors to the Impact of Sex on Heterogeneity in Flu Infection
Research
Principal Investigator ·
Awarded by National Institute of Allergy and Infectious Diseases ·
2022 - 2027
Characterization of a Novel E. coli Type III Secretion System Associated with Increased Patient Mortality
Research
Advisor ·
Awarded by National Institutes of Health ·
2022 - 2027
Medical Scientist Training Program
Inst. Training Prgm or CME
Preceptor ·
Awarded by National Institute of General Medical Sciences ·
2022 - 2027
The Molecular Mechanism and Pathophysiology of Robust STAT3 Signaling During Oral Salmonella Typhimurium Infection
Fellowship
Principal Investigator ·
Awarded by National Institutes of Health ·
2024 - 2027
Linking human TB genetic susceptibility loci to granuloma biology
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2022 - 2026
Role of the tumor NLRP3 inflammasome in the generation of anti-PD-1 antibody immunotherapy-associated toxicities
Research
Co Investigator ·
Awarded by National Cancer Institute ·
2021 - 2026
Cell and Molecular Biology Training Program
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
2021 - 2026
Human Genetic Variation Regulating Cellular Susceptibility to Zika Virus
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2024 - 2026
Genetic and Genomics Training Grant
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
2020 - 2025
HUMAN GENETIC VARIATION REGULATING SALMONELLA HOST-PATHOGEN INTERACTIONS AND DISEASE SUSCEPTIBILITY
Research
Principal Investigator ·
Awarded by National Institute of Allergy and Infectious Diseases ·
2015 - 2025
Duke CTSA (TL1) Year 5
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
2018 - 2024
Human Genetic Variation Regulating Transcriptional Response and Cellular Susceptibility to Influenza
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2021 - 2023
Medical Scientist Training Program
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
1997 - 2022
SALMONELLA HIJACKING OF STAT3 AND CONSEQUENCES FOR DISEASE
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2019 - 2022
Mechanisms of methylthioadenosine signaling during Salmonella infection
Fellowship
Principal Investigator ·
Awarded by National Institutes of Health ·
2019 - 2022
Regulation of Salmonella virulence by interspecies methylthioadenosine signaling
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2019 - 2022
Host-Directed Therapy to Circumvent Immune Evasion by Leishmania major
Fellowship
Principal Investigator ·
Awarded by Burroughs Wellcome Fund ·
2019 - 2021
Human Genetic Variance and Cellular Responses to Sexually Transmitted Infections
Research
Principal Investigator ·
Awarded by University of Maryland, Baltimore ·
2015 - 2021
STAT3-dependent manipulation of host transcription and immune responses by Salmonella
Fellowship
Principal Investigator ·
Awarded by National Institutes of Health ·
2019 - 2021
AN ATLAS OF SHARED GENETIC ARCHITECTURE CONNECTING CELL BIOLOGY AND HUMAN DISEASE
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2018 - 2021
Genetics Training Grant
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
1979 - 2020
Organization and Function of Cellular Structure
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
1975 - 2020
Human Genetic Variance and Cellular Responses to Sexually Transmitted Infections
Research
Principal Investigator ·
Awarded by University of Maryland ·
2009 - 2019
Characterization of a novel Salmonella regulator of IL-10 production and its role in pathogenesis
Fellowship
Principal Investigator ·
Awarded by National Institutes of Health ·
2016 - 2018
A role for pathogen-induced IL-10 production in susceptibility to MS
Research
Principal Investigator ·
Awarded by National Multiple Sclerosis Society ·
2014 - 2015
Functional genomics of human variation to Salmonella invasion
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2012 - 2015