Overview
I am a gut-brain neuroscientist.
Though my initial studies focused on GI physiology and nutrition, my expertise evolved to include neuroscience following the many personal stories, which have carefully sharpened my career vision along the way. While pursuing a Doctoral degree in Nutrition, a friend shared her struggles with obesity and gastric bypass surgery.
Surgery was a last resort but helped to reduced her body weight dramatically and resolved her diabetes. Yet, the most striking part of her story for me was that her perception of taste had been markedly transformed. Reshaping her gut caused her brain to convert a prior repulsion at the appearance of runny egg yolk into a strong craving to eat those same eggs.
Today, we are still a long way from understanding the full details of these intriguing conversations between our gut and our brain. But, the more we understand, the closer we are getting to treating disorders involving alterations in the perception of food in our gut.
My focus is to unveil how the brain perceives what the gut feels, how food in the intestine is sensed by our body, and how a sensory signal from a nutrient is transformed into an electrical signal that alters behavior.
Current Appointments & Affiliations
Recent Publications
A gut sense for a microbial pattern regulates feeding.
Journal Article Nature · September 2025 To coexist with its resident microorganisms, the host must have a sense to adjust its behaviour in response to them. In the intestine, a sense for nutrients transduced to the brain through neuroepithelial circuits guides appetitive choices1-5. However, a s ... Full text Link to item CiteGreat minds think alike: Glutamatergic signaling in the second brain.
Journal Article Neuron · April 2, 2025 The enteric nervous system is comprised of interconnected diverse cell types that control sensory and motor functions of the gut. In this issue of Neuron, Hamnett et al. demonstrate a novel role for distinct glutamatergic putative interneuron subtypes in c ... Full text Link to item CiteDeciphering visceral instincts: a scientific quest to unravel food choices from molecules to mind.
Journal Article Genes Dev · October 16, 2024 The study of biological mechanisms, while crucial, cannot fully explain complex phenomena like the instinct to eat. The mind-body connection, as exemplified by the concept of "voodoo death," highlights the profound influence of belief and cultural context ... Full text Link to item CiteRecent Grants
Neurobiology Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Neurological Disorders and Stroke · 2024 - 2029Endocrinology and Metabolism Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2024 - 2029Gut epithelial control of nutrient reward
ResearchMentor · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2024 - 2028View All Grants