P. Murali Doraiswamy
Professor of Psychiatry and Behavioral Sciences
Murali Doraiswamy MBBS FRCP is Professor of Psychiatry and Professor in Medicine at Duke University School of Medicine where he is a highly cited physician scientist at the Duke Institute for Brain Sciences. He is also a Senior Fellow at the Duke Center for the Study of Aging and an Affiliate Faculty at the Duke Center for Precision Medicine and Applied Genomics as well as the Duke Microbiome Center. He directs a clinical trials unit that has been involved in the development of many modern diagnostic tests, apps, algorithms, and therapeutics in wide use today. Prof Doraiswamy has been an advisor to leading government agencies, businesses and advocacy groups including the NIH, FDA, and WHO as well as numerous life science companies. He has served as the chair of the World Economic Forum’s Global Agenda Council on Brain Research and co-chaired the innovation advisory council for one of the world’s largest social impact funds dedicated to promoting innovative solutions to reverse age related disorders. He has lectured at leading global forums to advance the forefront of aging and neuroscience research. Moreover as an investigator on numerous landmark trials and co-author on more than 400 publications, he has received several awards in recognition of his scientific work. Additionally, he is a leading advocate for increasing funding for brain and behavioral research to help address great looming challenges in society posed by modern developments in the 21st century. His research has been featured in media outlets such as BBC, The New York Times, Scientific American, The Wall Street Journal, National Public Radio, CBS Evening news, The Dr Oz Show, Oprah, and TIME. He has appeared in acclaimed documentaries such as (Dis)Honesty: The Truth about Lies and Mysteries of the Brain. He is the co-author of a popular book The Alzheiemr's Action Plan. Prof. Doraiswamy also serves on the board of several global charities.
Current Research Interests
Digital Therapeutics
Biomarkers
Clinical Trials
Aging
Artificial Intelligence in Medicine
Current Appointments & Affiliations
- Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences, Psychiatry & Behavioral Sciences 2021
- Director, Neurocognitive Disorders Program, Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences, Psychiatry & Behavioral Sciences 2012
- Professor in Medicine, Medicine, Geriatrics, Medicine 2009
- Senior Fellow of the Center for the Study of Aging and Human Development, Center for the Study of Aging and Human Development, Institutes and Centers 1995
- Faculty Network Member of the Duke Institute for Brain Sciences, Duke Institute for Brain Sciences, University Institutes and Centers 2008
- Affiliate of the Duke Initiative for Science & Society, Duke Science & Society, Initiatives 2014
- Affiliate in the Duke Center for Applied Genomics and Precision Medicine, Duke Center for Applied Genomics and Precision Medicine, Medicine 2016
Contact Information
- 2400 Pratt Street North Pavil, 6th Floor, Room 6032, Durham, NC 27710
- 2400 Pratt Street North Pavil, Box 102505, Durham, NC 27710
-
(919) 684-5933
-
World Economic Forum Agenda
-
World Economic Forum Agenda - AI algorithms
- Background
-
Education, Training, & Certifications
- M.B.B.S., University of Madras (India) 1987
-
Previous Appointments & Affiliations
- Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2009 - 2020
- Chief, Division of Biological Psychiatry, Psychiatry & Behavioral Sciences, Clinical Science Departments 2001 - 2012
- Associate Professor in Medicine, Medicine, Geriatrics, Medicine 2001 - 2008
- Associate Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2005 - 2008
- Associate Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 1999 - 2005
- Assistant Professor in Medicine, Medicine, Geriatrics, Medicine 1999 - 2001
- Assistant Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 1995 - 1999
- Instructor, Temporary in the Department of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 1995
- Recognition
-
In the News
-
DEC 8, 2022 Department of Psychiatry and Behavioral Sciences -
JUL 28, 2022 American Psychiatric Association -
NOV 5, 2021 School of Medicine Magnify -
MAY 28, 2019 Duke Health News -
AUG 8, 2017 Duke Health News -
JAN 19, 2016 The New York Times -
DEC 29, 2015 The Wall Street Journal -
SEP 1, 2015 The New York Times -
SEP 1, 2015 the New York Times -
JUL 22, 2015 NPR’s “The Diane Rehm Show -
JUL 21, 2015 NBC News -
JUL 21, 2015 The New York Times -
JUL 21, 2015 The New York Times -
MAR 23, 2015 The Wall Street Journal -
FEB 19, 2015 The Wall Street Journal
-
- Expertise
-
Subject Headings
-
Global Scholarship
- Research
-
Selected Grants
- Genetic Modulations of Morbidity Compression: A Population-Based Study awarded by National Institutes of Health 2020 - 2025
- Duke Creating ADRD Researchers for the Next Generation - Stimulating Access to Research in Residency Program (CARiNG-StARR)" awarded by National Institutes of Health 2020 - 2024
- Racial and Geographic Disparities in Risk and Survival of Alzheimer's Disease and Related Dementias: Effects of Over/UnderDiagnosis and Disease Severity awarded by National Institutes of Health 2019 - 2024
- Sex Differences in Alzheimer's Disease Progression: Framingham Heart Study awarded by Cure Alzheimer's Fund 2022 - 2023
- Impact of Midlife and Late-Life Intake of Flavonoid-Rich Fruits on Dementia Risk in the Framingham Heart Study awarded by Boston University 2022 - 2023
- Metabolomic Signatures for Disease Sub-classification and Target Prioritization in AMP-AD awarded by National Institutes of Health 2018 - 2023
- Gut Liver Brain Biochemical Axis in Alzheimer's Disease awarded by National Institutes of Health 2018 - 2023
- Metabolic Networks and Pathways Predictive of Sex Differences in AD Risk and Responsiveness to Treatment awarded by National Institutes of Health 2018 - 2023
- Alzheimer's Disease Neuroimaging Initiative (ADNI4) awarded by University of Southern California 2022 - 2023
- Evaluating Effects in the Relationship between Traumatic Brain Injury and Alzheimer's Disease: Epidemiological Determinants, Their Health-Related Causes and the Resulting Disparities awarded by United States Army Medical Research Acquisition Activity 2020 - 2023
- Cognitive Training and Neuroplasticity in Mild Cognitive Impairment awarded by The Trustees of Columbia University 2020 - 2023
- Blueberry supplementation effects in Subjects at Risk for Alzheimer's Disease awarded by U.S. Highbush Blueberry Council 2022 - 2023
- ADNI-3 Diversity Supplement awarded by University of Southern California 2020 - 2022
- Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3) awarded by University of Southern California 2016 - 2022
- Cognitive training and neuroplasticity in Mild Cognitive Impairment awarded by Columbia University 2017 - 2022
- Does rifaximin improve cognition in patients with Alzheimer's disease?" using Manufacturer's drug XIFAXAN awarded by Bausch Health US LLC 2019 - 2022
- Phase 3 Clinical Trial for Agitation in Alzheimer's 15-AVP-786-301 awarded by Avanir Pharmaceuticals 2016 - 2021
- Phase 3 Clinical Trial for Agitation in Alzheimer's 15-AVP-786-303 awarded by Avanir Pharmaceuticals 2016 - 2021
- The Role of the Gut Microbiome and Metabolome in Alzheimer's Disease awarded by North Carolina Biotechnology Center 2021
- Effects of Traumatic Brain Injury and Post-Traumatic Stress Disorder and Alzheimer's Disease on Brain Tau in Vietnam Veterans using ADNI awarded by University of Southern California 2016 - 2021
- Predicting prebiotic effects on human microbiota, behavior, and cognition. awarded by Office of Naval Research 2018 - 2021
- A Clinical-Pathological Study of the Correspondence Between 18F-AV-1451 PET Imaging and Post-Mortem Assessment of Tau Pathology awarded by Avid Radiopharmaceuticals Inc 2015 - 2021
- High Resolution Intracortical DTI for Early Detection of Alzheimer¿s Disease awarded by Neuroradiology Education and Reserach Foundation (formerly Foundation of the ASNR) 2016 - 2020
- Effects of Traumatic Brain Injury (TBI) and Post Traumatic Stress Disorder (PTSD) on Alzheimer's Disease (AD) in Veterans Using Imaging and Biomarkers in the AD Neuroimaging Initiative (ADNI) (DoD) awarded by University of Southern California 2015 - 2020
- Effects of Traumatic Brain Injury and Post-Traumatic Stress Disorder on Alzheimer's Disease (AD) in Veterans with Mild Cognitive Impairment (MC) using the Alzheimer's disease neuroimaging initiative (ADNI) awarded by University of Southern California 2015 - 2020
- Metabolic Signatures Underlying Vascular Risk Factors for Alzheimer-type Dementias awarded by National Institutes of Health 2015 - 2020
- Metabolic Network Analysis of Biochemical Trajectories in Alzheimer's Disease awarded by National Institutes of Health 2017 - 2020
- A Biomarker-Based Trial of Plasmalogen Repletion in MCI/AD awarded by University of Pennsylvania 2019 - 2020
- Metabolic Networks and Pathways in Alzheimer's Disease awarded by National Institutes of Health 2014 - 2019
- An open label, multicenter study evaluating the imaging characteristics of follow up 18F-AV-1451 scan in subjects that participated in the confirmatory cohort of 18F-AV-1451-A05 awarded by Avid Radiopharmaceuticals Inc 2016 - 2019
- Lifestyle, CVD Risk and Cognitive Impairment awarded by National Institutes of Health 2011 - 2018
- EVP-6124-025 awarded by FORUM Pharmaceuticals Inc. 2014 - 2017
- EVP-6124-026 awarded by FORUM Pharmaceuticals Inc. 2014 - 2017
- Baseline Bio-molecular Models to Predict Infectious Disease Susceptibility awarded by Defense Advanced Research Projects Agency 2015 - 2016
- Pilot Combination Trial of Mild Cognitive Impairment with Depression Supplement awarded by Research Foundation for Mental Hygiene, Inc. 2013 - 2016
- Pilot Combination Trial of Mild Cognitive Impairment with Depression awarded by Research Foundation for Mental Hygiene, Inc. 2011 - 2015
- Cortical Beta-amyloid Levels and Neurocognitive Performance After Cardiac Surgery awarded by National Institutes of Health 2011 - 2014
- Vascular Depression: Longitudinal Changes awarded by National Institutes of Health 2007 - 2011
- Metabolic Signatures for Alzheimer's Disease awarded by National Institutes of Health 2007 - 2011
- PREMIER Mental Health Interventions Training Program awarded by National Institutes of Health 2002 - 2010
- fMRI Studies in Early Alzheimer's Disease awarded by National Institutes of Health 2001 - 2008
- Exercise Training And Depression In Older Adults awarded by National Institutes of Health 1998 - 2007
- Treatment Outcomes of Vascular Depression awarded by National Institutes of Health 2001 - 2007
- Development of the Inventory of Depressive Symptomatology awarded by National Institutes of Health 2003 - 2006
- A Clinical Trial of Donepezil for Down Syndrome awarded by National Institutes of Health 2001 - 2004
- A Placebo...Extract Hypericum Perforatum In Major Depressi awarded by National Institutes of Health 1998 - 2001
- Alzheimers Disease-- Antemortem Markers awarded by National Institutes of Health 1995 - 1998
-
External Relationships
- AHEL Ltd
- Alzheon
- Compass Pathways Plc ADR
- Cornell University
- Cure Alzheimer Fund
- Evidation Health
- IMD Business School
- Live Love Laugh - non-profit organization devoted to improving mental health.
- Lumos Labs
- MarvelBiome
- Massachusetts Institute of Technology
- Nestle
- Otsuka America Pharmaceuticals
- Transposon Therapeutics
- UMethod
- Publications & Artistic Works
-
Selected Publications
-
Academic Articles
-
Akushevich I, Kravchenko J, Yashkin A, Doraiswamy PM, Hill CV, Alzheimer’s Disease and Related Dementia Health Disparities Collaborative Group. Expanding the scope of health disparities research in Alzheimer's disease and related dementias: Recommendations from the "Leveraging Existing Data and Analytic Methods for Health Disparities Research Related to Aging and Alzheimer's Disease and Related Dementias" Workshop Series. Alzheimers Dement (Amst). 2023;15(1):e12415.Full Text Link to Item
-
Ding H, Li Y, Ang TFA, Liu Y, Devine S, Au R, et al. Reproductive Markers in Alzheimer’s Disease Progression: The Framingham Heart Study. Journal of Prevention of Alzheimer’S Disease. 2023 Jan 1;Full Text
-
Hayes J, Carvajal-Velez L, Hijazi Z, Ahs JW, Doraiswamy PM, El Azzouzi FA, et al. You Can't Manage What You Do Not Measure - Why Adolescent Mental Health Monitoring Matters. J Adolesc Health. 2023 Jan;72(1S):S7–8.Full Text Link to Item
-
Petrella JR, Michael AM, Qian M, Nwosu A, Sneed J, Goldberg TE, et al. Impact of Computerized Cognitive Training on Default Mode Network Connectivity in Subjects at Risk for Alzheimer's Disease: A 78-week Randomized Controlled Trial. J Alzheimers Dis. 2023;91(1):483–94.Full Text Link to Item
-
Nunes JC, Carroll MK, Mahaffey KW, Califf RM, Doraiswamy PM, Short S, et al. General Anxiety Disorder-7 Questionnaire as a marker of low socioeconomic status and inequity. J Affect Disord. 2022 Nov 15;317:287–97.Full Text Link to Item
-
Baloni P, Arnold M, Buitrago L, Nho K, Moreno H, Huynh K, et al. Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer's disease. Commun Biol. 2022 Oct 8;5(1):1074.Full Text Link to Item
-
Zheng H, Petrella JR, Doraiswamy PM, Lin G, Hao W, Alzheimer’s Disease Neuroimaging Initiative. Data-driven causal model discovery and personalized prediction in Alzheimer's disease. Npj Digit Med. 2022 Sep 8;5(1):137.Full Text Link to Item
-
Califf RM, Wong C, Doraiswamy PM, Hong DS, Miller DP, Mega JL, et al. Importance of Social Determinants in Screening for Depression. J Gen Intern Med. 2022 Aug;37(11):2736–43.Full Text Link to Item
-
Scott J, Hockey S, Ospina-Pinillos L, Doraiswamy PM, Alvarez-Jimenez M, Hickie I. Research to Clinical Practice-Youth seeking mental health information online and its impact on the first steps in the patient journey. Acta Psychiatr Scand. 2022 Mar;145(3):301–14.Full Text Link to Item
-
Califf RM, Wong C, Doraiswamy PM, Hong DS, Miller DP, Mega JL, et al. Biological and clinical correlates of the patient health questionnaire-9: exploratory cross-sectional analyses of the baseline health study. Bmj Open. 2022 Jan 4;12(1):e054741.Full Text Link to Item
-
Choi J, Lee S, Motter JN, Kim H, Andrews H, Doraiswamy PM, et al. Models of depressive pseudoamnestic disorder. Alzheimers Dement (N Y). 2022;8(1):e12335.Full Text Link to Item
-
Liu C, Li Y, Nwosu A, Ang TFA, Liu Y, Devine S, et al. Sex-specific biomarkers in Alzheimer's disease progression: Framingham Heart Study. Alzheimers Dement (Amst). 2022;14(1):e12369.Full Text Link to Item
-
Nwosu A, Boardman S, Husain MM, Doraiswamy PM. Digital therapeutics for mental health: Is attrition the Achilles heel? Front Psychiatry. 2022;13:900615.Full Text Link to Item
-
Prescott JW, Doraiswamy PM, Gamberger D, Benzinger T, Petrella JR, Dominantly Inherited Alzheimer Network. Diffusion Tensor MRI Structural Connectivity and PET Amyloid Burden in Preclinical Autosomal Dominant Alzheimer Disease: The DIAN Cohort. Radiology. 2022 Jan;302(1):143–50.Full Text Link to Item
-
Shuren J, Doraiswamy PM. Digital Therapeutics for MCI and Alzheimer's disease: A Regulatory Perspective - Highlights From The Clinical Trials on Alzheimer's Disease conference (CTAD). J Prev Alzheimers Dis. 2022;9(2):236–40.Full Text Link to Item
-
Suhocki PV, Ronald JS, Diehl AME, Murdoch DM, Doraiswamy PM. Probing gut-brain links in Alzheimer's disease with rifaximin. Alzheimers Dement (N Y). 2022;8(1):e12225.Full Text Link to Item
-
Motter JN, Lee S, Sneed JR, Doraiswamy PM, Pelton GH, Petrella JR, et al. Cortical thickness predicts remission of depression with antidepressants in patients with late-life depression and cognitive impairment. J Affect Disord. 2021 Dec 1;295:438–45.Full Text Link to Item
-
Wang Q, Davis PB, Qi X, Chen SG, Gurney ME, Perry G, et al. Gut-microbiota-microglia-brain interactions in Alzheimer's disease: knowledge-based, multi-dimensional characterization. Alzheimers Res Ther. 2021 Oct 20;13(1):177.Full Text Link to Item
-
Grzesiak E, Bent B, McClain MT, Woods CW, Tsalik EL, Nicholson BP, et al. Assessment of the Feasibility of Using Noninvasive Wearable Biometric Monitoring Sensors to Detect Influenza and the Common Cold Before Symptom Onset. Jama Netw Open. 2021 Sep 1;4(9):e2128534.Full Text Open Access Copy Link to Item
-
Occhipinti J-A, Skinner A, Doraiswamy PM, Fox C, Herrman H, Saxena S, et al. Mental health: build predictive models to steer policy. Nature. 2021 Sep;597(7878):633–6.Full Text Link to Item
-
James OG, Linares AR, Hellegers C, Doraiswamy PM, Wong TZ. Evaluating Alzheimer Disease With Flortaucipir and Florbetapir PET: A Clinical Case Series. Clin Nucl Med. 2021 Jul 1;46(7):605–8.Full Text Open Access Copy Link to Item
-
Hu WT, Ozturk T, Kollhoff A, Wharton W, Christina Howell J, Alzheimer’s Disease Neuroimaging Initiative. Higher CSF sTNFR1-related proteins associate with better prognosis in very early Alzheimer's disease. Nat Commun. 2021 Jun 28;12(1):4001.Full Text Link to Item
-
Baumel BS, Doraiswamy PM, Sabbagh M, Wurtman R. Potential Neuroregenerative and Neuroprotective Effects of Uridine/Choline-Enriched Multinutrient Dietary Intervention for Mild Cognitive Impairment: A Narrative Review. Neurol Ther. 2021 Jun;10(1):43–60.Full Text Link to Item
-
Doraiswamy PM, Chilukuri MM, Ariely D, Linares AR. Physician Perceptions of Catching COVID-19: Insights from a Global Survey. Journal of General Internal Medicine. 2021 Jun;36(6):1832–4.Full Text
-
Lu M, Pontecorvo MJ, Devous MD, Arora AK, Galante N, McGeehan A, et al. Aggregated Tau Measured by Visual Interpretation of Flortaucipir Positron Emission Tomography and the Associated Risk of Clinical Progression of Mild Cognitive Impairment and Alzheimer Disease: Results From 2 Phase III Clinical Trials. Jama Neurol. 2021 Apr 1;78(4):445–53.Full Text Link to Item
-
Doraiswamy PM, Chilukuri MM, Linares AR, Bramstedt KA. Are we ready for COVID-19’s golden passport? Insights from a global physician survey. Journal of Health and Social Sciences. 2021 Mar 1;6(1):83–90.
-
Blumenthal JA, Babyak MA, Craighead WE, Davidson J, Hinderliter A, Hoffman B, et al. The role of comorbid anxiety in exercise and depression trials: Secondary analysis of the SMILE-II randomized clinical trial. Depress Anxiety. 2021 Feb;38(2):124–33.Full Text Link to Item
-
Nho K, Kueider-Paisley A, Arnold M, MahmoudianDehkordi S, Risacher SL, Louie G, et al. Serum metabolites associated with brain amyloid beta deposition, cognition and dementia progression. Brain Commun. 2021;3(3):fcab139.Full Text Link to Item
-
Baloni P, Funk CC, Yan J, Yurkovich JT, Kueider-Paisley A, Nho K, et al. Metabolic Network Analysis Reveals Altered Bile Acid Synthesis and Metabolism in Alzheimer's Disease. Cell Rep Med. 2020 Nov 17;1(8):100138.Full Text Link to Item
-
Franzmeier N, Suárez-Calvet M, Frontzkowski L, Moore A, Hohman TJ, Morenas-Rodriguez E, et al. Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration. Mol Neurodegener. 2020 Oct 8;15(1):57.Full Text Link to Item
-
Bernath MM, Bhattacharyya S, Nho K, Barupal DK, Fiehn O, Baillie R, et al. Serum triglycerides in Alzheimer disease: Relation to neuroimaging and CSF biomarkers. Neurology. 2020 May 19;94(20):e2088–98.Full Text Link to Item
-
Arnold M, Nho K, Kueider-Paisley A, Massaro T, Huynh K, Brauner B, et al. Sex and APOE ε4 genotype modify the Alzheimer's disease serum metabolome. Nat Commun. 2020 Mar 2;11(1):1148.Full Text Link to Item
-
Blumenthal JA, Smith PJ, Mabe S, Hinderliter A, Welsh-Bohmer K, Browndyke JN, et al. Longer Term Effects of Diet and Exercise on Neurocognition: 1-Year Follow-up of the ENLIGHTEN Trial. J Am Geriatr Soc. 2020 Mar;68(3):559–68.Full Text Link to Item
-
Doraiswamy PM, Blease C, Bodner K. Artificial intelligence and the future of psychiatry: Insights from a global physician survey. Artif Intell Med. 2020 Jan;102:101753.Full Text Link to Item
-
Bodner KA, Goldberg TE, Devanand DP, Doraiswamy PM. Advancing Computerized Cognitive Training for MCI and Alzheimer's Disease in a Pandemic and Post-pandemic World. Front Psychiatry. 2020;11:557571.Full Text Link to Item
-
Ng NF, Osman AM, Kerlan KR, Doraiswamy PM, Schafer RJ. Computerized Cognitive Training by Healthy Older and Younger Adults: Age Comparisons of Overall Efficacy and Selective Effects on Cognition. Front Neurol. 2020;11:564317.Full Text Link to Item
-
Sabbagh MN, Boada M, Borson S, Chilukuri M, Doraiswamy PM, Dubois B, et al. Rationale for Early Diagnosis of Mild Cognitive Impairment (MCI) Supported by Emerging Digital Technologies. J Prev Alzheimers Dis. 2020;7(3):158–64.Full Text Link to Item
-
Sabbagh MN, Boada M, Borson S, Doraiswamy PM, Dubois B, Ingram J, et al. Early Detection of Mild Cognitive Impairment (MCI) in an At-Home Setting. J Prev Alzheimers Dis. 2020;7(3):171–8.Full Text Link to Item
-
Smith PJ, Mabe SM, Sherwood A, Doraiswamy PM, Welsh-Bohmer KA, Burke JR, et al. Metabolic and Neurocognitive Changes Following Lifestyle Modification: Examination of Biomarkers from the ENLIGHTEN Randomized Clinical Trial. J Alzheimers Dis. 2020;77(4):1793–803.Full Text Link to Item
-
Horgusluoglu-Moloch E, Risacher SL, Crane PK, Hibar D, Thompson PM, Saykin AJ, et al. Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways. Sci Rep. 2019 Oct 10;9(1):14498.Full Text Link to Item
-
Nho K, Kueider-Paisley A, Ahmad S, MahmoudianDehkordi S, Arnold M, Risacher SL, et al. Association of Altered Liver Enzymes With Alzheimer Disease Diagnosis, Cognition, Neuroimaging Measures, and Cerebrospinal Fluid Biomarkers. Jama Netw Open. 2019 Jul 3;2(7):e197978.Full Text Open Access Copy Link to Item
-
Schilling LP, Pascoal TA, Zimmer ER, Mathotaarachchi S, Shin M, de Mello Rieder CR, et al. Regional Amyloid-β Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer's Dementia. Mol Neurobiol. 2019 Jul;56(7):4916–24.Full Text Link to Item
-
Ong SS, Proia AD, Whitson HE, Farsiu S, Doraiswamy PM, Lad EM. Ocular amyloid imaging at the crossroad of Alzheimer's disease and age-related macular degeneration: implications for diagnosis and therapy. J Neurol. 2019 Jul;266(7):1566–77.Full Text Link to Item
-
Pontecorvo MJ, Devous MD, Kennedy I, Navitsky M, Lu M, Galante N, et al. A multicentre longitudinal study of flortaucipir (18F) in normal ageing, mild cognitive impairment and Alzheimer's disease dementia. Brain. 2019 Jun 1;142(6):1723–35.Full Text Link to Item
-
Goudey B, Fung BJ, Schieber C, Faux NG, Alzheimer’s Disease Metabolomics Consortium, Alzheimer’s Disease Neuroimaging Initiative. A blood-based signature of cerebrospinal fluid Aβ1-42 status. Sci Rep. 2019 Mar 11;9(1):4163.Full Text Link to Item
-
Moran C, Beare R, Wang W, Callisaya M, Srikanth V, Alzheimer’s Disease Neuroimaging Initiative (ADNI). Type 2 diabetes mellitus, brain atrophy, and cognitive decline. Neurology. 2019 Feb 19;92(8):e823–30.Full Text Link to Item
-
Privitera GJ, King-Shepard QW, Cuifolo KN, Doraiswamy PM. Differential food intake and food choice by depression and body mass index levels following a mood manipulation in a buffet-style setting. J Health Psychol. 2019 Feb;24(2):199–208.Full Text Link to Item
-
Nho K, Kueider-Paisley A, MahmoudianDehkordi S, Arnold M, Risacher SL, Louie G, et al. Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers. Alzheimers Dement. 2019 Feb;15(2):232–44.Full Text Link to Item
-
Blumenthal JA, Smith PJ, Mabe S, Hinderliter A, Lin P-H, Liao L, et al. Lifestyle and neurocognition in older adults with cognitive impairments: A randomized trial. Neurology. 2019 Jan 15;92(3):e212–23.Full Text Link to Item
-
MahmoudianDehkordi S, Arnold M, Nho K, Ahmad S, Jia W, Xie G, et al. Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome. Alzheimers Dement. 2019 Jan;15(1):76–92.Full Text Open Access Copy Link to Item
-
Petrella JR, Hao W, Rao A, Doraiswamy PM. Computational Causal Modeling of the Dynamic Biomarker Cascade in Alzheimer's Disease. Comput Math Methods Med. 2019;2019:6216530.Full Text Link to Item
-
Smilnak GJ, Deans JR, Doraiswamy PM, Stinnett S, Whitson HE, Lad EM. Comorbidity of age-related macular degeneration with Alzheimer's disease: A histopathologic case-control study. Plos One. 2019;14(9):e0223199.Full Text Link to Item
-
Smith PJ, Mabe S, Sherwood A, Babyak MA, Doraiswamy PM, Welsh-Bohmer KA, et al. Association Between Insulin Resistance, Plasma Leptin, and Neurocognition in Vascular Cognitive Impairment. J Alzheimers Dis. 2019;71(3):921–9.Full Text Link to Item
-
Tolbert S, Liu Y, Hellegers C, Petrella JR, Weiner MW, Wong TZ, et al. Financial Management Skills in Aging, MCI and Dementia: Cross Sectional Relationship to 18F-Florbetapir PET Cortical β-amyloid Deposition. J Prev Alzheimers Dis. 2019;6(4):274–82.Full Text Link to Item
-
Motter JN, Pelton GH, D’Antonio K, Rushia SN, Pimontel MA, Petrella JR, et al. Clinical and radiological characteristics of early versus late mild cognitive impairment in patients with comorbid depressive disorder. Int J Geriatr Psychiatry. 2018 Dec;33(12):1604–12.Full Text Link to Item
-
Devanand DP, Pelton GH, D’Antonio K, Ciarleglio A, Scodes J, Andrews H, et al. Donepezil Treatment in Patients With Depression and Cognitive Impairment on Stable Antidepressant Treatment: A Randomized Controlled Trial. Am J Geriatr Psychiatry. 2018 Oct;26(10):1050–60.Full Text Link to Item
-
Ong SS, Doraiswamy PM, Lad EM. Controversies and Future Directions of Ocular Biomarkers in Alzheimer Disease. Jama Neurol. 2018 Jun 1;75(6):650–1.Full Text Link to Item
-
Sohn D, Shpanskaya K, Lucas JE, Petrella JR, Saykin AJ, Tanzi RE, et al. Sex Differences in Cognitive Decline in Subjects with High Likelihood of Mild Cognitive Impairment due to Alzheimer's disease. Sci Rep. 2018 May 10;8(1):7490.Full Text Link to Item
-
Lu D, Popuri K, Ding GW, Balachandar R, Beg MF, Alzheimer’s Disease Neuroimaging Initiative. Multimodal and Multiscale Deep Neural Networks for the Early Diagnosis of Alzheimer's Disease using structural MR and FDG-PET images. Sci Rep. 2018 Apr 9;8(1):5697.Full Text Link to Item
-
Mills PJ, Peterson CT, Pung MA, Patel S, Weiss L, Wilson KL, et al. Change in Sense of Nondual Awareness and Spiritual Awakening in Response to a Multidimensional Well-Being Program. J Altern Complement Med. 2018 Apr;24(4):343–51.Full Text Link to Item
-
Klinger RY, James OG, Borges-Neto S, Bisanar T, Li Y-J, Qi W, et al. 18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery. Anesthesiology. 2018 Apr;128(4):728–44.Full Text Link to Item
-
Mahjoub I, Mahjoub MA, Rekik I, Alzheimer’s Disease Neuroimaging Initiative. Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states. Sci Rep. 2018 Mar 7;8(1):4103.Full Text Link to Item
-
Privitera GJ, Welling D, Tejada G, Sweazy N, Cuifolo KN, King-Shepard QW, et al. No calorie comfort: Viewing and drawing "comfort foods" similarly augment positive mood for those with depression. J Health Psychol. 2018 Mar;23(4):598–607.Full Text Link to Item
-
Doraiswamy PM, Narayan VA, Manji HK. Mobile and pervasive computing technologies and the future of Alzheimer's clinical trials. Npj Digit Med. 2018;1:1.Full Text Link to Item
-
Varma VR, Oommen AM, Varma S, Casanova R, An Y, Andrews RM, et al. Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study. Plos Med. 2018 Jan;15(1):e1002482.Full Text Link to Item
-
White RW, Doraiswamy PM, Horvitz E. Detecting neurodegenerative disorders from web search signals. Npj Digit Med. 2018;1:8.Full Text Link to Item
-
Padmanabhan K, Nudelman K, Harenberg S, Bello G, Sohn D, Shpanskaya K, et al. Characterizing gene and protein crosstalks in subjects at risk of developing Alzheimer's disease: A new computational approach. Processes. 2017 Sep 1;5(3).Full Text
-
Toledo JB, Arnold M, Kastenmüller G, Chang R, Baillie RA, Han X, et al. Metabolic network failures in Alzheimer's disease: A biochemical road map. Alzheimers Dement. 2017 Sep;13(9):965–84.Full Text Link to Item
-
Singanamalli A, Wang H, Madabhushi A, Alzheimer’s Disease Neuroimaging Initiative. Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer's Disease via Fusion of Clinical, Imaging and Omic Features. Sci Rep. 2017 Aug 15;7(1):8137.Full Text Link to Item
-
Gamberger D, Lavrač N, Srivatsa S, Tanzi RE, Doraiswamy PM. Identification of clusters of rapid and slow decliners among subjects at risk for Alzheimer's disease. Sci Rep. 2017 Jul 28;7(1):6763.Full Text Link to Item
-
Mattsson N, Andreasson U, Zetterberg H, Blennow K, Alzheimer’s Disease Neuroimaging Initiative. Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease. Jama Neurol. 2017 May 1;74(5):557–66.Full Text Link to Item
-
Lin KA, Rundel C, Doraiswamy PM, Alzheimer’s Disease Neuroimaging Initiative. Serum SHBG Levels are not Associated with Longitudinal Cognitive Decline in Mild Cognitive Impairment. J Alzheimers Dis. 2017;55(3):1123–30.Full Text Link to Item
-
Pontecorvo MJ, Siderowf A, Dubois B, Doraiswamy PM, Frisoni GB, Grundman M, et al. Effectiveness of Florbetapir PET Imaging in Changing Patient Management. Dement Geriatr Cogn Disord. 2017;44(3–4):129–43.Full Text Link to Item
-
Blumenthal JA, Smith PJ, Mabe S, Hinderliter A, Welsh-Bohmer K, Browndyke JN, et al. Lifestyle and Neurocognition in Older Adults With Cardiovascular Risk Factors and Cognitive Impairment. Psychosom Med. 2017;79(6):719–27.Full Text Link to Item
-
Lee E, Giovanello KS, Saykin AJ, Xie F, Kong D, Wang Y, et al. Single-nucleotide polymorphisms are associated with cognitive decline at Alzheimer's disease conversion within mild cognitive impairment patients. Alzheimers Dement (Amst). 2017;8:86–95.Full Text Link to Item
-
Padmanabhan K, Shpanskaya K, Bello G, Doraiswamy PM, Samatova NF. Toward Personalized Network Biomarkers in Alzheimer's Disease: Computing Individualized Genomic and Protein Crosstalk Maps. Front Aging Neurosci. 2017;9:315.Full Text Link to Item
-
Peterson CT, Lucas J, John-Williams LS, Thompson JW, Moseley MA, Patel S, et al. Identification of Altered Metabolomic Profiles Following a Panchakarma-based Ayurvedic Intervention in Healthy Subjects: The Self-Directed Biological Transformation Initiative (SBTI). Sci Rep. 2016 Sep 9;6:32609.Full Text Link to Item
-
Mills PJ, Wilson KL, Pung MA, Weiss L, Patel S, Doraiswamy PM, et al. The Self-Directed Biological Transformation Initiative and Well-Being. J Altern Complement Med. 2016 Aug;22(8):627–34.Full Text Link to Item
-
Iturria-Medina Y, Sotero RC, Toussaint PJ, Mateos-Pérez JM, Evans AC, Alzheimer’s Disease Neuroimaging Initiative. Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis. Nat Commun. 2016 Jun 21;7:11934.Full Text Link to Item
-
Risacher SL, McDonald BC, Tallman EF, West JD, Farlow MR, Unverzagt FW, et al. Association Between Anticholinergic Medication Use and Cognition, Brain Metabolism, and Brain Atrophy in Cognitively Normal Older Adults. Jama Neurol. 2016 Jun 1;73(6):721–32.Full Text Link to Item
-
Prescott JW, Guidon A, Doraiswamy PM, Choudhury KR, Liu C, Petrella JR, et al. The Alzheimer Structural Connectome: Changes in Cortical Network Topology with Increased Amyloid Plaque Burden. Radiology. 2016 Apr;279(1):328.Full Text Link to Item
-
Hunsberger JG, Rao M, Kurtzberg J, Bulte JWM, Atala A, LaFerla FM, et al. Accelerating stem cell trials for Alzheimer's disease. Lancet Neurol. 2016 Feb;15(2):219–30.Full Text Open Access Copy Link to Item
-
Weingarten CP, Doraiswamy PM, Fisher MPA. A New Spin on Neural Processing: Quantum Cognition. Front Hum Neurosci. 2016;10:541.Full Text Link to Item
-
Kim S, Nho K, Ramanan VK, Lai D, Foroud TM, Lane K, et al. Genetic Influences on Plasma Homocysteine Levels in African Americans and Yoruba Nigerians. J Alzheimers Dis. 2016;49(4):991–1003.Full Text Link to Item
-
Motter JN, Pimontel MA, Rindskopf D, Devanand DP, Doraiswamy PM, Sneed JR. Computerized cognitive training and functional recovery in major depressive disorder: A meta-analysis. J Affect Disord. 2016 Jan 1;189:184–91.Full Text Link to Item
-
Shin J, Doraiswamy PM. Underrepresentation of African-Americans in Alzheimer's Trials: A Call for Affirmative Action. Front Aging Neurosci. 2016;8:123.Full Text Link to Item
-
Cecchi M, Moore DK, Sadowsky CH, Solomon PR, Doraiswamy PM, Smith CD, et al. A clinical trial to validate event-related potential markers of Alzheimer's disease in outpatient settings. Alzheimers Dement (Amst). 2015 Dec;1(4):387–94.Full Text Link to Item
-
Lin KA, Choudhury KR, Rathakrishnan BG, Marks DM, Petrella JR, Doraiswamy PM, et al. Marked gender differences in progression of mild cognitive impairment over 8 years. Alzheimers Dement (N Y). 2015 Sep 1;1(2):103–10.Full Text Link to Item
-
Ayton S, Faux NG, Bush AI, Alzheimer’s Disease Neuroimaging Initiative. Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE. Nat Commun. 2015 May 19;6:6760.Full Text Link to Item
-
James OG, Doraiswamy PM, Borges-Neto S. PET Imaging of Tau Pathology in Alzheimer's Disease and Tauopathies. Front Neurol. 2015;6:38.Full Text Open Access Copy Link to Item
-
Lin KA, Doraiswamy PM. When mars versus venus is not a cliché: Gender differences in the neurobiology of Alzheimer's disease. Frontiers in Neurology. 2015 Jan 1;6(JAN).Full Text
-
Privitera GJ, McGrath HK, Windus BA, Doraiswamy PM. Eat now or later: self-control as an overlapping cognitive mechanism of depression and obesity. Plos One. 2015;10(3):e0123136.Full Text Link to Item
-
Kong D, Giovanello KS, Wang Y, Lin W, Lee E, Fan Y, et al. Predicting Alzheimer's Disease Using Combined Imaging-Whole Genome SNP Data. J Alzheimers Dis. 2015;46(3):695–702.Full Text Link to Item
-
Motter JN, Devanand DP, Doraiswamy PM, Sneed JR. Computerized Cognitive Training for Major Depressive Disorder: What's Next? Front Psychiatry. 2015;6:137.Full Text Link to Item
-
Sundman M, Doraiswamy PM, Morey RA. Neuroimaging assessment of early and late neurobiological sequelae of traumatic brain injury: implications for CTE. Front Neurosci. 2015;9:334.Full Text Open Access Copy Link to Item
-
Shpanskaya KS, Choudhury KR, Hostage C, Murphy KR, Petrella JR, Doraiswamy PM, et al. Educational attainment and hippocampal atrophy in the Alzheimer's disease neuroimaging initiative cohort. J Neuroradiol. 2014 Dec;41(5):350–7.Full Text Link to Item
-
Blumenthal JA, Doraiswamy PM. Exercise to combat depression. Jama. 2014 Nov 26;312(20):2166–7.Full Text Link to Item
-
Disabato BM, Morris C, Hranilovich J, D’Angelo GM, Zhou G, Wu N, et al. Comparison of brain structural variables, neuropsychological factors, and treatment outcome in early-onset versus late-onset late-life depression. Am J Geriatr Psychiatry. 2014 Oct;22(10):1039–46.Full Text Link to Item
-
Prescott JW, Guidon A, Doraiswamy PM, Roy Choudhury K, Liu C, Petrella JR, et al. The Alzheimer structural connectome: changes in cortical network topology with increased amyloid plaque burden. Radiology. 2014 Oct;273(1):175–84.Full Text Link to Item
-
Doraiswamy PM, Sperling RA, Johnson K, Reiman EM, Wong TZ, Sabbagh MN, et al. Florbetapir F 18 amyloid PET and 36-month cognitive decline: a prospective multicenter study. Mol Psychiatry. 2014 Sep;19(9):1044–51.Full Text Link to Item
-
Keefe RSE, McClintock SM, Roth RM, Doraiswamy PM, Tiger S, Madhoo M. Cognitive effects of pharmacotherapy for major depressive disorder: a systematic review. J Clin Psychiatry. 2014 Aug;75(8):864–76.Full Text Link to Item
-
Zannas AS, Doraiswamy PM, Shpanskaya KS, Murphy KR, Petrella JR, Burke JR, et al. Impact of ¹⁸F-florbetapir PET imaging of β-amyloid neuritic plaque density on clinical decision-making. Neurocase. 2014 Aug;20(4):466–73.Full Text Link to Item
-
Tur-Kaspa I, Jeelani R, Doraiswamy PM. Preimplantation genetic diagnosis for inherited neurological disorders. Nat Rev Neurol. 2014 Jul;10(7):417–24.Full Text Link to Item
-
Gerhard T, Huybrechts K, Olfson M, Schneeweiss S, Bobo WV, Doraiswamy PM, et al. Comparative mortality risks of antipsychotic medications in community-dwelling older adults. Br J Psychiatry. 2014 Jul;205(1):44–51.Full Text Link to Item
-
Hostage CA, Choudhury KR, Murali Doraiswamy P, Petrella JR, Alzheimer’s Disease Neuroimaging Initiative. Mapping the effect of the apolipoprotein E genotype on 4-year atrophy rates in an Alzheimer disease-related brain network. Radiology. 2014 Apr;271(1):211–9.Full Text Link to Item
-
Uflacker A, Doraiswamy PM, Rechitsky S, See T, Geschwind M, Tur-Kaspa I. Preimplantation genetic diagnosis (PGD) for genetic prion disorder due to F198S mutation in the PRNP gene. Jama Neurol. 2014 Apr;71(4):484–6.Full Text Link to Item
-
Pelton GH, Andrews H, Roose SP, Marcus SM, D’Antonio K, Husn H, et al. Donepezil treatment of older adults with cognitive impairment and depression (DOTCODE study): clinical rationale and design. Contemp Clin Trials. 2014 Mar;37(2):200–8.Full Text Link to Item
-
Zannas AS, Okuno Y, Doraiswamy PM. Cholinesterase inhibitors and Pisa syndrome: a pharmacovigilance study. Pharmacotherapy. 2014 Mar;34(3):272–8.Full Text Link to Item
-
Rathakrishnan BG, Doraiswamy PM, Petrella JR. Science to practice: translating automated brain MRI volumetry in Alzheimer's disease from research to routine diagnostic use in the work-up of dementia. Front Neurol. 2014 Jan 9;4:216.Full Text Link to Item
-
Dugger BN, Clark CM, Serrano G, Mariner M, Bedell BJ, Coleman RE, et al. Neuropathologic heterogeneity does not impair florbetapir-positron emission tomography postmortem correlates. J Neuropathol Exp Neurol. 2014 Jan;73(1):72–80.Full Text Link to Item
-
Ferrer I, López-González I, Carmona M, Arregui L, Dalfó E, Torrejón-Escribano B, et al. Glial and neuronal tau pathology in tauopathies: characterization of disease-specific phenotypes and tau pathology progression. J Neuropathol Exp Neurol. 2014 Jan;73(1):81–97.Full Text Link to Item
-
Lampert EJ, Roy Choudhury K, Hostage CA, Rathakrishnan B, Weiner M, Petrella JR, et al. Brain atrophy rates in first degree relatives at risk for Alzheimer's. Neuroimage Clin. 2014;6:340–6.Full Text Link to Item
-
Lin KA, Doraiswamy PM. When Mars Versus Venus is Not a Cliché: Gender Differences in the Neurobiology of Alzheimer's Disease. Front Neurol. 2014;5:288.Full Text Link to Item
-
Billeke P, Boardman S, Doraiswamy PM. Social cognition in major depressive disorder: A new paradigm? Translational Neuroscience. 2013 Dec 1;4(4):437–47.Full Text
-
Johnson KA, Sperling RA, Gidicsin CM, Carmasin JS, Maye JE, Coleman RE, et al. Florbetapir (F18-AV-45) PET to assess amyloid burden in Alzheimer's disease dementia, mild cognitive impairment, and normal aging. Alzheimers Dement. 2013 Oct;9(5 Suppl):S72–83.Full Text Link to Item
-
Klinger RY, James OG, Wong TZ, Newman MF, Doraiswamy PM, Mathew JP. Cortical β-amyloid levels and neurocognitive performance after cardiac surgery. Bmj Open. 2013 Sep 20;3(9):e003669.Full Text Open Access Copy Link to Item
-
Murphy KR, Landau SM, Choudhury KR, Hostage CA, Shpanskaya KS, Sair HI, et al. Mapping the effects of ApoE4, age and cognitive status on 18F-florbetapir PET measured regional cortical patterns of beta-amyloid density and growth. Neuroimage. 2013 Sep;78:474–80.Full Text Link to Item
-
Atluri G, Padmanabhan K, Fang G, Steinbach M, Petrella JR, Lim K, et al. Complex biomarker discovery in neuroimaging data: Finding a needle in a haystack. Neuroimage Clin. 2013 Aug 7;3:123–31.Full Text Link to Item
-
Hoffman KB, Demakas A, Erdman CB, Dimbil M, Doraiswamy PM. Neuropsychiatric adverse effects of oseltamivir in the FDA Adverse Event Reporting System, 1999-2012. Bmj. 2013 Jul 23;347:f4656.Full Text Link to Item
-
Motsinger-Reif AA, Zhu H, Kling MA, Matson W, Sharma S, Fiehn O, et al. Comparing metabolomic and pathologic biomarkers alone and in combination for discriminating Alzheimer's disease from normal cognitive aging. Acta Neuropathol Commun. 2013 Jun 27;1:28.Full Text Link to Item
-
Sternberg DA, Ballard K, Hardy JL, Katz B, Doraiswamy MM, Scanlon MD. The largest human cognitive performance dataset reveals insights into the effects of lifestyle factors and aging. Frontiers in Human Neuroscience. 2013 Jun 3;(JUN).Full Text
-
Petrella JR, Doraiswamy PM. From the bridges of Konigsberg to the fields of Alzheimer: connecting the dots. Neurology. 2013 Apr 9;80(15):1360–2.Full Text Link to Item
-
Kaddurah-Daouk R, Zhu H, Sharma S, Bogdanov M, Rozen SG, Matson W, et al. Alterations in metabolic pathways and networks in Alzheimer's disease. Transl Psychiatry. 2013 Apr 9;3(4):e244.Full Text Link to Item
-
Tariot PN, Doraiswamy PM. Alzheimer's disease: the importance of early diagnosis and appropriate management. J Clin Psychiatry. 2013 Mar;74(3):e06.Full Text Link to Item
-
Sperling RA, Johnson KA, Doraiswamy PM, Reiman EM, Fleisher AS, Sabbagh MN, et al. Amyloid deposition detected with florbetapir F 18 ((18)F-AV-45) is related to lower episodic memory performance in clinically normal older individuals. Neurobiol Aging. 2013 Mar;34(3):822–31.Full Text Link to Item
-
Shaffer JL, Petrella JR, Sheldon FC, Choudhury KR, Calhoun VD, Coleman RE, et al. Predicting cognitive decline in subjects at risk for Alzheimer disease by using combined cerebrospinal fluid, MR imaging, and PET biomarkers. Radiology. 2013 Feb;266(2):583–91.Full Text Link to Item
-
Burt T, Hughes L, Kalali A, Doraiswamy PM. Dementia Clinical Research in India. 2013 Jan 1;231–46.Full Text
-
Fleisher AS, Chen K, Liu X, Ayutyanont N, Roontiva A, Thiyyagura P, et al. Apolipoprotein E ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease. Neurobiol Aging. 2013 Jan;34(1):1–12.Full Text Link to Item
-
Grandpierre A, Chopra D, Doraiswamy PM, Tanzi R, Kafatos MC. A multidisciplinary approach to mind and consciousness. Neuroquantology. 2013 Jan 1;11(4):607–17.Full Text
-
Hostage CA, Roy Choudhury K, Doraiswamy PM, Petrella JR, Alzheimer’s Disease Neuroimaging Initiative. Dissecting the gene dose-effects of the APOE ε4 and ε2 alleles on hippocampal volumes in aging and Alzheimer's disease. Plos One. 2013;8(2):e54483.Full Text Link to Item
-
Lampert EJ, Roy Choudhury K, Hostage CA, Petrella JR, Doraiswamy PM, Alzheimer’s Disease Neuroimaging Initiative. Prevalence of Alzheimer's pathologic endophenotypes in asymptomatic and mildly impaired first-degree relatives. Plos One. 2013;8(4):e60747.Full Text Link to Item
-
Lombard J, Doraiswamy PM. What is the role of pharmacogenetics in clinical psychiatry? Expert Opin Drug Metab Toxicol. 2013 Jan;9(1):1–4.Full Text Link to Item
-
Privitera GJ, Misenheimer ML, Doraiswamy PM. From weight loss to weight gain: appetite changes in major depressive disorder as a mirror into brain-environment interactions. Front Psychol. 2013;4:873.Full Text Link to Item
-
Sternberg DA, Ballard K, Hardy JL, Katz B, Doraiswamy PM, Scanlon M. The largest human cognitive performance dataset reveals insights into the effects of lifestyle factors and aging. Front Hum Neurosci. 2013;7:292.Full Text Link to Item
-
Vishwanathan SP, Malott L, Chellappan S, Doraiswamy PM. An empirical study on symptoms of heavier Internet usage among young adults. 2013 Ieee International Conference on Advanced Networks and Telecommunications Systems, Ants 2013. 2013 Jan 1;Full Text
-
Blumenthal JA, Smith PJ, Welsh-Bohmer K, Babyak MA, Browndyke J, Lin P-H, et al. Can lifestyle modification improve neurocognition? Rationale and design of the ENLIGHTEN clinical trial. Contemp Clin Trials. 2013 Jan;34(1):60–9.Full Text Link to Item
-
Grundman M, Pontecorvo MJ, Salloway SP, Doraiswamy PM, Fleisher AS, Sadowsky CH, et al. Potential impact of amyloid imaging on diagnosis and intended management in patients with progressive cognitive decline. Alzheimer Dis Assoc Disord. 2013;27(1):4–15.Full Text Link to Item
-
Sheline YI, Disabato BM, Hranilovich J, Morris C, D’Angelo G, Pieper C, et al. Treatment course with antidepressant therapy in late-life depression. Am J Psychiatry. 2012 Nov;169(11):1185–93.Full Text Link to Item
-
Doraiswamy PM, Sperling RA, Coleman RE, Johnson KA, Reiman EM, Davis MD, et al. Amyloid-β assessed by florbetapir F 18 PET and 18-month cognitive decline: a multicenter study. Neurology. 2012 Oct 16;79(16):1636–44.Full Text Link to Item
-
Blumenthal JA, Sherwood A, Babyak MA, Watkins LL, Smith PJ, Hoffman BM, et al. Exercise and pharmacological treatment of depressive symptoms in patients with coronary heart disease: results from the UPBEAT (Understanding the Prognostic Benefits of Exercise and Antidepressant Therapy) study. J Am Coll Cardiol. 2012 Sep 18;60(12):1053–63.Full Text Link to Item
-
Barch DM, DʼAngelo G, Pieper C, Wilkins CH, Welsh-Bohmer K, Taylor W, et al. Cognitive improvement following treatment in late-life depression: relationship to vascular risk and age of onset. Am J Geriatr Psychiatry. 2012 Aug;20(8):682–90.Full Text Link to Item
-
Clark CM, Pontecorvo MJ, Beach TG, Bedell BJ, Coleman RE, Doraiswamy PM, et al. Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study. Lancet Neurol. 2012 Aug;11(8):669–78.Full Text Link to Item
-
Doraiswamy PM. Is the idle mind a Devil's workshop? Biol Psychiatry. 2012 May 1;71(9):765–6.Full Text Link to Item
-
Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, et al. Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3985–90.Full Text Link to Item
-
Doraiswamy PM. Silent cerebrovascular events and Alzheimer's disease: an overlooked opportunity for prevention? Am J Psychiatry. 2012 Mar;169(3):251–4.Full Text Link to Item
-
Hurko O, Black SE, Doody R, Doraiswamy PM, Gamst A, Kaye J, et al. The ADNI Publication Policy: commensurate recognition of critical contributors who are not authors. Neuroimage. 2012 Feb 15;59(4):4196–200.Full Text Link to Item
-
Balasubramaniam M, Telles S, Doraiswamy PM. Yoga on our minds: a systematic review of yoga for neuropsychiatric disorders. Front Psychiatry. 2012;3:117.Full Text Link to Item
-
Zannas AS, Wong TZ, Doraiswamy PM. How much is a picture worth? Putting amyloid imaging to the test. Dement Geriatr Cogn Dis Extra. 2012 Jan;2(1):649–51.Full Text Link to Item
-
Seibyl J, Zubal IG, Jennings D, Marek K, Doraiswamy PM. Molecular PET imaging in multicenter Alzheimer's therapeutic trials: current trends and implementation strategies. Expert Rev Neurother. 2011 Dec;11(12):1783–93.Full Text Link to Item
-
Fleisher AS, Chen K, Liu X, Roontiva A, Thiyyagura P, Ayutyanont N, et al. Using positron emission tomography and florbetapir F18 to image cortical amyloid in patients with mild cognitive impairment or dementia due to Alzheimer disease. Arch Neurol. 2011 Nov;68(11):1404–11.Full Text Link to Item
-
Layous K, Chancellor J, Lyubomirsky S, Wang L, Doraiswamy PM. Delivering happiness: translating positive psychology intervention research for treating major and minor depressive disorders. J Altern Complement Med. 2011 Aug;17(8):675–83.Full Text Link to Item
-
Benjamin S, Doraiswamy PM. Review of the use of mirtazapine in the treatment of depression. Expert Opin Pharmacother. 2011 Jul;12(10):1623–32.Full Text Link to Item
-
Kaddurah-Daouk R, Rozen S, Matson W, Han X, Hulette CM, Burke JR, et al. Metabolomic changes in autopsy-confirmed Alzheimer's disease. Alzheimers Dement. 2011 May;7(3):309–17.Full Text Link to Item
-
Petrella JR, Sheldon FC, Prince SE, Calhoun VD, Doraiswamy PM. Default mode network connectivity in stable vs progressive mild cognitive impairment. Neurology. 2011 Feb 8;76(6):511–7.Full Text Link to Item
-
Clark CM, Schneider JA, Bedell BJ, Beach TG, Bilker WB, Mintun MA, et al. Use of florbetapir-PET for imaging beta-amyloid pathology. Jama. 2011 Jan 19;305(3):275–83.Full Text Link to Item
-
Farlow MR, Doraiswamy PM, Meng X, Cooke K, Somogyi M. The effect of vascular risk factors on the efficacy of rivastigmine patch and capsule treatment in Alzheimer's disease. Dement Geriatr Cogn Dis Extra. 2011 Jan;1(1):150–62.Full Text Link to Item
-
Taylor WD, Macfall JR, Boyd B, Payne ME, Sheline YI, Krishnan RR, et al. One-year change in anterior cingulate cortex white matter microstructure: relationship with late-life depression outcomes. Am J Geriatr Psychiatry. 2011 Jan;19(1):43–52.Full Text Link to Item
-
Han X, Rozen S, Boyle SH, Hellegers C, Cheng H, Burke JR, et al. Metabolomics in early Alzheimer's disease: identification of altered plasma sphingolipidome using shotgun lipidomics. Plos One. 2011;6(7):e21643.Full Text Link to Item
-
Hoffman BM, Babyak MA, Craighead WE, Sherwood A, Doraiswamy PM, Coons MJ, et al. Exercise and pharmacotherapy in patients with major depression: one-year follow-up of the SMILE study. Psychosom Med. 2011;73(2):127–33.Full Text Link to Item
-
Doraiswamy PM, Fannon D. e-Interview. Psychiatrist. 2010 Dec 1;34(12).Full Text
-
Smith PJ, Blumenthal JA, Babyak MA, Watkins LL, Hinderliter A, Hoffman BM, et al. Cerebrovascular risk factors and cerebral hyperintensities among middle-aged and older adults with major depression. Am J Geriatr Psychiatry. 2010 Sep;18(9):848–52.Full Text Link to Item
-
Doraiswamy PM, Bernstein IH, Rush AJ, Kyutoku Y, Carmody TJ, Macleod L, et al. Diagnostic utility of the Quick Inventory of Depressive Symptomatology (QIDS-C16 and QIDS-SR16) in the elderly. Acta Psychiatr Scand. 2010 Sep;122(3):226–34.Full Text Link to Item
-
Sheline YI, Pieper CF, Barch DM, Welsh-Bohmer K, McKinstry RC, MacFall JR, et al. Support for the vascular depression hypothesis in late-life depression: results of a 2-site, prospective, antidepressant treatment trial. Arch Gen Psychiatry. 2010 Mar;67(3):277–85.Full Text Link to Item
-
Hoffman BM, Sherwood A, Smith PJ, Babyak MA, Doraiswamy PM, Hinderliter A, et al. Cardiovascular disease risk, vascular health and erectile dysfunction among middle-aged, clinically depressed men. Int J Impot Res. 2010;22(1):30–5.Full Text Link to Item
-
Doraiswamy PM. Are we using relevant models of dementia? European Journal of Neurology. 2009 Oct 1;16:662–662.Link to Item
-
Hoffman BM, Babyak MA, Sherwood A, Hill EE, Patidar SM, Doraiswamy PM, et al. Effects of aerobic exercise on sexual functioning in depressed adults. Mental Health and Physical Activity. 2009 Jun 1;2(1):23–8.Full Text
-
Smith PJ, Blumenthal JA, Babyak MA, Doraiswamy PM, Hinderliter A, Hoffman BM, et al. Intima-media thickness and age of first depressive episode. Biol Psychol. 2009 Mar;80(3):361–4.Full Text Link to Item
-
Petrella JR, Prince SE, Krishnan S, Husn H, Kelley L, Doraiswamy PM. Effects of donepezil on cortical activation in mild cognitive impairment: a pilot double-blind placebo-controlled trial using functional MR imaging. Ajnr Am J Neuroradiol. 2009 Feb;30(2):411–6.Full Text Link to Item
-
Woo SL, Prince SE, Petrella JR, Hellegers C, Doraiswamy PM. Modulation of a human memory circuit by subsyndromal depression in late life: a functional magnetic resonance imaging study. Am J Geriatr Psychiatry. 2009 Jan;17(1):24–9.Full Text Link to Item
-
Baker RA, Pikalov A, Tran Q-V, Kremenets T, Arani RB, Doraiswamy PM. Atypical antipsychotic drugs and diabetes mellitus in the US Food and Drug Administration Adverse Event database: a systematic Bayesian signal detection analysis. Psychopharmacol Bull. 2009;42(1):11–31.Link to Item
-
Taylor WD, Kuchibhatla M, Payne ME, Macfall JR, Sheline YI, Krishnan KR, et al. Frontal white matter anisotropy and antidepressant remission in late-life depression. Plos One. 2008 Sep 24;3(9):e3267.Full Text Link to Item
-
Hoffman BM, Blumenthal JA, Babyak MA, Smith PJ, Rogers SD, Doraiswamy PM, et al. Exercise fails to improve neurocognition in depressed middle-aged and older adults. Med Sci Sports Exerc. 2008 Jul;40(7):1344–52.Full Text Link to Item
-
Woo SL, Prince SE, Hellegers C, Petrella JR, Doraiswamy PM. Modulation of Human Memory Circuit by Minor Depression in Late Life: An fMRI Study. American Journal of Geriatric Psychiatry. 2008 Mar 1;16(3):A98–A98.Link to Item
-
Blumenthal JA, Sherwood A, Babyak MA, Doraiswamy PM, Hoffman BM. Response to letters to the editor [3]. Psychosomatic Medicine. 2008 Feb 1;70(2):264–5.Full Text
-
Prince SE, Woo S, Doraiswamy PM, Petrella JR. Functional MRI in the early diagnosis of Alzheimer's disease: is it time to refocus? Expert Rev Neurother. 2008 Feb;8(2):169–75.Full Text Link to Item
-
Henderson DC, Doraiswamy PM. Prolactin-related and metabolic adverse effects of atypical antipsychotic agents. J Clin Psychiatry. 2008;69 Suppl 1:32–44.Link to Item
-
Petrella JR, Mattay VS, Doraiswamy PM. Imaging genetics of brain longevity and mental wellness: the next frontier? Radiology. 2008 Jan;246(1):20–32.Full Text Link to Item
-
Tupler LA, Krishnan KRR, Greenberg DL, Marcovina SM, Payne ME, MacFall JR, et al. Predicting memory decline in normal elderly: genetics, MRI, and cognitive reserve. Neurobiol Aging. 2007 Nov;28(11):1644–56.Full Text Link to Item
-
Petrella JR, Prince SE, Wang L, Hellegers C, Doraiswamy PM. Prognostic value of posteromedial cortex deactivation in mild cognitive impairment. Plos One. 2007 Oct 31;2(10):e1104.Full Text Link to Item
-
Kaddurah-Daouk R, McEvoy J, Baillie RA, Lee D, Yao JK, Doraiswamy PM, et al. Metabolomic mapping of atypical antipsychotic effects in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):934–45.Full Text Link to Item
-
Petrella JR, Wang L, Krishnan S, Slavin MJ, Prince SE, Tran T-TT, et al. Cortical deactivation in mild cognitive impairment: high-field-strength functional MR imaging. Radiology. 2007 Oct;245(1):224–35.Full Text Link to Item
-
Doraiswamy PM, Xiong GL. Does Meditation Enhance Cognition and Brain Longevity? Ann N Y Acad Sci. 2007 Sep 28;Full Text Link to Item
-
Slavin MJ, Sandstrom CK, Tran T-TT, Doraiswamy PM, Petrella JR. Hippocampal volume and the Mini-Mental State Examination in the diagnosis of amnestic mild cognitive impairment. Ajr Am J Roentgenol. 2007 May;188(5):1404–10.Full Text Link to Item
-
Doraiswamy PM. PET scanning in mild cognitive impairment. N Engl J Med. 2007 Mar 15;356(11):1175.Full Text Link to Item
-
Robertson B, Wang L, Diaz MT, Aiello M, Gersing K, Beyer J, et al. Effect of bupropion extended release on negative emotion processing in major depressive disorder: a pilot functional magnetic resonance imaging study. J Clin Psychiatry. 2007 Feb;68(2):261–7.Full Text Link to Item
-
Blumenthal JA, Babyak MA, Doraiswamy PM, Watkins L, Hoffman BM, Barbour KA, et al. Exercise and pharmacotherapy in the treatment of major depressive disorder. Psychosom Med. 2007;69(7):587–96.Full Text Link to Item
-
Blumenthal JA, Sherwood A, Rogers SD, Babyak MA, Doraiswamy PM, Watkins L, et al. Understanding prognostic benefits of exercise and antidepressant therapy for persons with depression and heart disease: the UPBEAT study--rationale, design, and methodological issues. Clin Trials. 2007;4(5):548–59.Full Text Link to Item
-
Doraiswamy PM, Babyak MA, Hennig T, Trivedi R, White WD, Mathew JP, et al. Donepezil for cognitive decline following coronary artery bypass surgery: a pilot randomized controlled trial. Psychopharmacol Bull. 2007;40(2):54–62.Link to Item
-
Doraiswamy PM, Schott G, Star K, Edwards R, Mueller-Oerlinghausen B. Atypical antipsychotics and pituitary neoplasms in the WHO database. Psychopharmacol Bull. 2007;40(1):74–6.Link to Item
-
Smith PJ, Blumenthal JA, Babyak MA, Hoffman BM, Doraiswamy PM, Waugh R, et al. Cerebrovascular risk factors, vascular disease, and neuropsychological outcomes in adults with major depression. Psychosom Med. 2007;69(6):578–86.Full Text Link to Item
-
Taylor WD, Doraiswamy PM, Krishnan KR. Evidence-based treatment of psychiatric disorders with comorbid medical illnesses: the need for large simple clinical trials. Psychopharmacol Bull. 2007;40(4):5–11.Link to Item
-
Varia I, Venkataraman S, Hellegers C, Gersing K, Doraiswamy PM. Effect of mirtazapine orally disintegrating tablets on health-related quality of life in elderly depressed patients with comorbid medical disorders: a pilot study. Psychopharmacol Bull. 2007;40(1):47–56.Link to Item
-
Young AJ, Johnson S, Steffens DC, Doraiswamy PM. Coenzyme Q10: a review of its promise as a neuroprotectant. Cns Spectr. 2007 Jan;12(1):62–8.Full Text Link to Item
-
Heller JH, Spiridigliozzi GA, Crissman BG, Sullivan JA, Eells RL, Li JS, et al. Safety and efficacy of rivastigmine in adolescents with Down syndrome: a preliminary 20-week, open-label study. J Child Adolesc Psychopharmacol. 2006 Dec;16(6):755–65.Full Text Link to Item
-
Sandstrom CK, Krishnan S, Slavin MJ, Tran T-TT, Doraiswamy PM, Petrella JR. Hippocampal atrophy confounds template-based functional MR imaging measures of hippocampal activation in patients with mild cognitive impairment. Ajnr Am J Neuroradiol. 2006 Sep;27(8):1622–7.Link to Item
-
Li Y-J, Scott WK, Zhang L, Lin P-I, Oliveira SA, Skelly T, et al. Revealing the role of glutathione S-transferase omega in age-at-onset of Alzheimer and Parkinson diseases. Neurobiol Aging. 2006 Aug;27(8):1087–93.Full Text Link to Item
-
Petrella JR, Krishnan S, Slavin MJ, Tran T-TT, Murty L, Doraiswamy PM. Mild cognitive impairment: evaluation with 4-T functional MR imaging. Radiology. 2006 Jul;240(1):177–86.Full Text Link to Item
-
Lin P-I, Martin ER, Browning-Large CA, Schmechel DE, Welsh-Bohmer KA, Doraiswamy PM, et al. Parsing the genetic heterogeneity of chromosome 12q susceptibility genes for Alzheimer disease by family-based association analysis. Neurogenetics. 2006 Jul;7(3):157–65.Full Text Link to Item
-
Lyketsos CG, Colenda CC, Beck C, Blank K, Doraiswamy MP, Kalunian DA, et al. Position statement of the American Association for Geriatric Psychiatry regarding principles of care for patients with dementia resulting from Alzheimer disease. Am J Geriatr Psychiatry. 2006 Jul;14(7):561–72.Full Text Link to Item
-
Sheline YI, Barch DM, Garcia K, Gersing K, Pieper C, Welsh-Bohmer K, et al. Cognitive function in late life depression: relationships to depression severity, cerebrovascular risk factors and processing speed. Biol Psychiatry. 2006 Jul 1;60(1):58–65.Full Text Link to Item
-
Krishnan S, Slavin MJ, Tran T-TT, Doraiswamy PM, Petrella JR. Accuracy of spatial normalization of the hippocampus: implications for fMRI research in memory disorders. Neuroimage. 2006 Jun;31(2):560–71.Full Text Link to Item
-
Szarfman A, Tonning JM, Levine JG, Doraiswamy PM. Atypical antipsychotics and pituitary tumors: a pharmacovigilance study. Pharmacotherapy. 2006 Jun;26(6):748–58.Full Text Link to Item
-
Doraiswamy PM, Husain MM. Anticholinergic drugs and elderly people: a no brainer? Lancet Neurol. 2006 May;5(5):379–80.Full Text Link to Item
-
Slifer MA, Martin ER, Bronson PG, Browning-Large C, Doraiswamy PM, Welsh-Bohmer KA, et al. Lack of association between UBQLN1 and Alzheimer disease. Am J Med Genet B Neuropsychiatr Genet. 2006 Apr 5;141B(3):208–13.Full Text Link to Item
-
Pomara N, Doraiswamy PM, Willoughby LM, Roth AE, Mulsant BH, Sidtis JJ, et al. Elevation in plasma Abeta42 in geriatric depression: a pilot study. Neurochem Res. 2006 Mar;31(3):341–9.Full Text Link to Item
-
Szarfman A, Doraiswamy PM, Tonning JM, Levine JG. Association between pathologic gambling and parkinsonian therapy as detected in the Food and Drug Administration Adverse Event database. Arch Neurol. 2006 Feb;63(2):299–300.Full Text Link to Item
-
Doraiswamy PM, Xiong GL. Pharmacological strategies for the prevention of Alzheimer's disease. Expert Opin Pharmacother. 2006 Jan;7(1):1–10.Full Text Link to Item
-
Murali Doraiswamy P. Increased pituitary volume in ...psychosis study. Neuropsychopharmacology. 2006 Jan;31(1):243.Full Text Link to Item
-
Doraiswamy PM, Varia I, Hellegers C, Wagner HR, Clary GL, Beyer JL, et al. A randomized controlled trial of paroxetine for noncardiac chest pain. Psychopharmacol Bull. 2006;39(1):15–24.Link to Item
-
Mori E, Hashimoto M, Krishnan KR, Doraiswamy PM. What constitutes clinical evidence for neuroprotection in Alzheimer disease: support for the cholinesterase inhibitors? Alzheimer Dis Assoc Disord. 2006;20(2 Suppl 1):S19–26.Full Text Link to Item
-
Krishnan S, Talley BD, Slavin MJ, Doraiswamy PM, Petrella JR. Current status of functional MR imaging, perfusion-weighted imaging, and diffusion-tensor imaging in Alzheimer's disease diagnosis and research. Neuroimaging Clin N Am. 2005 Nov;15(4):853–xi.Full Text Link to Item
-
Petrella JR, Doraiswamy PM. Alzheimer's disease: 100 Years of progress. Neuroimaging Clinics of North America. 2005 Nov 1;15(4).Full Text
-
Soher BJ, Doraiswamy PM, Charles HC. A review of 1H MR spectroscopy findings in Alzheimer's disease. Neuroimaging Clin N Am. 2005 Nov;15(4):847–xi.Full Text Link to Item
-
Xiong GL, Benson A, Doraiswamy PM. Statins and cognition: what can we learn from existing randomized trials? Cns Spectr. 2005 Nov;10(11):867–74.Full Text Link to Item
-
Xiong G, Doraiswamy PM. Combination drug therapy for Alzheimer's disease: what is evidence-based, and what is not? Geriatrics. 2005 Jun;60(6):22–6.Link to Item
-
Benson AD, Slavin MJ, Tran T-T, Petrella JR, Doraiswamy PM. Screening for Early Alzheimer's Disease: Is There Still a Role for the Mini-Mental State Examination? Prim Care Companion J Clin Psychiatry. 2005;7(2):62–9.Full Text Link to Item
-
Petrella JR, Townsend BA, Jha AP, Ziajko LA, Slavin MJ, Lustig C, et al. Increasing memory load modulates regional brain activity in older adults as measured by fMRI. J Neuropsychiatry Clin Neurosci. 2005;17(1):75–83.Full Text Link to Item
-
Taylor WD, Doraiswamy PM. A systematic review of antidepressant placebo-controlled trials for geriatric depression: limitations of current data and directions for the future. Neuropsychopharmacology. 2004 Dec;29(12):2285–99.Full Text Link to Item
-
Pomara N, Willoughby LM, Sidtis JJ, Doraiswamy PM, Wesnes KA, Cooper TB, et al. Baseline plasma GABA: its relationship to the adverse effects of acute lorazepam administration on cognition in the elderly. Neurochem Res. 2004 Dec;29(12):2311–5.Full Text Link to Item
-
Doraiswamy PM, Rao SM. Treating cognitive deficits in multiple sclerosis: are we there yet? Neurology. 2004 Nov 9;63(9):1552–3.Full Text Link to Item
-
Heller JH, Spiridigliozzi GA, Doraiswamy PM, Sullivan JA, Crissman BG, Kishnani PS. Donepezil effects on language in children with Down syndrome: results of the first 22-week pilot clinical trial. Am J Med Genet A. 2004 Oct 15;130A(3):325–6.Full Text Link to Item
-
Raja PV, Blumenthal JA, Doraiswamy PM. Cognitive deficits following coronary artery bypass grafting: prevalence, prognosis, and therapeutic strategies. Cns Spectr. 2004 Oct;9(10):763–72.Full Text Link to Item
-
Szarfman A, Tonning JM, Doraiswamy PM. Pharmacovigilance in the 21st century: new systematic tools for an old problem. Pharmacotherapy. 2004 Sep;24(9):1099–104.Full Text Link to Item
-
van der Walt JM, Dementieva YA, Martin ER, Scott WK, Nicodemus KK, Kroner CC, et al. Analysis of European mitochondrial haplogroups with Alzheimer disease risk. Neurosci Lett. 2004 Jul 15;365(1):28–32.Full Text Link to Item
-
Doraiswamy PM, Finefrock AE. Metals in our minds: therapeutic implications for neurodegenerative disorders. Lancet Neurol. 2004 Jul;3(7):431–4.Full Text Link to Item
-
Sheikh JI, Cassidy EL, Doraiswamy PM. Erratum: Efficacy, safety, and tolerability of sertraline in patients with late-life depression and comorbid medical illness (Journal of the American Geriatrics Society (January 2004) (90)). Journal of the American Geriatrics Society. 2004 Jul 1;52(7):1228.Full Text
-
Sheikh JI, Cassidy EL, Doraiswamy PM. Efficacy, safety, and tolerability of sertraline in patients with late-life depression and comorbid medical illness (vol 52, pg 90, 2004). Journal of the American Geriatrics Society. 2004 Jul 1;52(7):1228–1228.Link to Item
-
Taylor DH, Sloan FA, Doraiswamy PM. Marked increase in Alzheimer's disease identified in medicare claims records between 1991 and 1999. J Gerontol a Biol Sci Med Sci. 2004 Jul;59(7):762–6.Full Text Link to Item
-
Koller EA, Weber J, Doraiswamy PM, Schneider BS. A survey of reports of quetiapine-associated hyperglycemia and diabetes mellitus. J Clin Psychiatry. 2004 Jun;65(6):857–63.Full Text Link to Item
-
Sair HI, Doraiswamy PM, Petrella JR. In vivo amyloid imaging in Alzheimer's disease. Neuroradiology. 2004 Feb;46(2):93–104.Full Text Link to Item
-
Sheikh JI, Cassidy EL, Doraiswamy PM, Salomon RM, Hornig M, Holland PJ, et al. Efficacy, safety, and tolerability of sertraline in patients with late-life depression and comorbid medical illness. J Am Geriatr Soc. 2004 Jan;52(1):86–92.Full Text Link to Item
-
Doraiswamy PM, Steffens DC, McQuoid DR. Statin use and hippocampal volumes in elderly subjects at risk for Alzheimer's disease: a pilot observational study. Am J Alzheimers Dis Other Demen. 2004;19(5):275–8.Full Text Link to Item
-
Silvertooth EJ, Doraiswamy PM, Clary GL, Babyak MA, Wilkerson N, Hellegars C, et al. Citalopram and quality of life in lung transplant recipients. Psychosomatics. 2004;45(3):271–2.Full Text Link to Item
-
Doraiswamy PM, Krishnan KRR, Oxman T, Jenkyn LR, Coffey DJ, Burt T, et al. Does antidepressant therapy improve cognition in elderly depressed patients? J Gerontol a Biol Sci Med Sci. 2003 Dec;58(12):M1137–44.Full Text Link to Item
-
Krishnan KRR, Charles HC, Doraiswamy PM, Mintzer J, Weisler R, Yu X, et al. Randomized, placebo-controlled trial of the effects of donepezil on neuronal markers and hippocampal volumes in Alzheimer's disease. Am J Psychiatry. 2003 Nov;160(11):2003–11.Full Text Link to Item
-
Koller EA, Cross JT, Doraiswamy PM, Malozowski SN. Pancreatitis associated with atypical antipsychotics: from the Food and Drug Administration's MedWatch surveillance system and published reports. Pharmacotherapy. 2003 Sep;23(9):1123–30.Full Text Link to Item
-
Doraiswamy PM. The role of the N-methyl-D-aspartate receptor in Alzheimer's disease: therapeutic potential. Curr Neurol Neurosci Rep. 2003 Sep;3(5):373–8.Full Text Link to Item
-
Oliveira SA, Martin ER, Scott WK, Nicodemus KK, Small GW, Schmechel DE, et al. The Q7R Saitohin gene polymorphism is not associated with Alzheimer disease. Neurosci Lett. 2003 Aug 28;347(3):143–6.Full Text Link to Item
-
Finefrock AE, Bush AI, Doraiswamy PM. Current status of metals as therapeutic targets in Alzheimer's disease. J Am Geriatr Soc. 2003 Aug;51(8):1143–8.Full Text Link to Item
-
Wagstaff LR, Mitton MW, Arvik BM, Doraiswamy PM. Statin-associated memory loss: analysis of 60 case reports and review of the literature. Pharmacotherapy. 2003 Jul;23(7):871–80.Full Text Link to Item
-
Koller EA, Cross JT, Doraiswamy PM, Schneider BS. Risperidone-associated diabetes mellitus: a pharmacovigilance study. Pharmacotherapy. 2003 Jun;23(6):735–44.Full Text Link to Item
-
Pomara N, Murali Doraiswamy P. Does increased platelet release of Abeta peptide contribute to brain abnormalities in individuals with depression? Med Hypotheses. 2003 May;60(5):640–3.Full Text Link to Item
-
Arnold KR. Ginkgo and memory. Jama. 2003 Feb 5;289(5):546.Full Text Link to Item
-
Doraiswamy PM, Pomara N. Ginkgo and memory. Jama. 2003 Feb 5;289(5):547.Full Text Link to Item
-
Petrella JR, Coleman RE, Doraiswamy PM. Neuroimaging and early diagnosis of Alzheimer disease: a look to the future. Radiology. 2003 Feb;226(2):315–36.Full Text Link to Item
-
Heller JH, Spiridigliozzi GA, Sullivan JA, Doraiswamy PM, Krishnan RR, Kishnani PS. Donepezil for the treatment of language deficits in adults with Down syndrome: a preliminary 24-week open trial. Am J Med Genet A. 2003 Jan 15;116A(2):111–6.Full Text Link to Item
-
Doraiswamy PM, Varia IM. Mirtazapine treatment of elderly depressed patients with comorbid medical disorders: Impact on health-related quality of life. International Psychogeriatrics. 2003 Jan 1;15:227–227.Link to Item
-
Doraiswamy PM. Hippocampal volume and magnetic resonance imaging markers in clinical trials. International Psychogeriatrics. 2003 Jan 1;15:86–86.Link to Item
-
Doraiswamy PM. Comparing treatment data in medically comorbid patients. International Psychogeriatrics. 2003 Jan 1;15:370–370.Link to Item
-
Doraiswamy PM. Interventions for mild cognitive impairment and Alzheimer disease: new strategies, new hope. Am J Geriatr Psychiatry. 2003;11(2):120–2.Link to Item
-
Doraiswamy PM. Alzheimer's disease and the glutamate NMDA receptor. Psychopharmacol Bull. 2003;37(2):41–9.Link to Item
-
Pomara N, Greenberg WM, Branford MD, Doraiswamy PM. Therapeutic implications of HPA axis abnormalities in Alzheimer's disease: review and update. Psychopharmacol Bull. 2003;37(2):120–34.Link to Item
-
Herman S, Blumenthal JA, Babyak M, Khatri P, Craighead WE, Krishnan KR, et al. Exercise therapy for depression in middle-aged and older adults: predictors of early dropout and treatment failure. Health Psychol. 2002 Nov;21(6):553–63.Link to Item
-
Koller EA, Doraiswamy PM. Olanzapine-associated diabetes mellitus. Pharmacotherapy. 2002 Jul;22(7):841–52.Full Text Link to Item
-
Petrella J, Sair H, Hart S, Doraiswamy PM, Ziajko L, Lustig C, et al. Cortical activation in patients with mild cognitive impairment: Assessment with event-related functional MRI during a visual working memory task. Neurobiology of Aging. 2002 Jul 1;23(1):S349–S349.Link to Item
-
Pomara N, Doraiswamy PM, Tun H. Mifepristone (RU 486) for Alzheimer's disease - A pilot study. Neurobiology of Aging. 2002 Jul 1;23(1):S83–S83.Link to Item
-
Clary GL, Palmer SM, Doraiswamy PM. Mood disorders and chronic obstructive pulmonary disease: current research and future needs. Curr Psychiatry Rep. 2002 Jun;4(3):213–21.Full Text Link to Item
-
Pomara N, Doraiswamy PM, Tun H, Ferris S. Mifepristone (RU 486) for Alzheimer's disease. Neurology. 2002 May 14;58(9):1436.Full Text Link to Item
-
Doraiswamy PM, Krishnan KRR, Anand R, Sohn H, Danyluk J, Hartman RD, et al. Long-term effects of rivastigmine in moderately severe Alzheimer's disease: does early initiation of therapy offer sustained benefits? Prog Neuropsychopharmacol Biol Psychiatry. 2002 May;26(4):705–12.Full Text Link to Item
-
Hypericum Depression Trial Study Group, Davidson JRT, Gadde KM, Fairbank JA, Krishnan KRR, Califf RM, et al. Effect of Hypericum perforatum (St John's wort) in major depressive disorder: a randomized controlled trial. Jama. 2002 Apr 10;287(14):1807–14.Full Text Link to Item
-
Townsend B, Petrella J, Doraiswamy PM, McCarthy G, Jha AP, Lustig C. Working memory load dissociates transient and delay activity in normal aging. Journal of Cognitive Neuroscience. 2002 Apr 1;114–114.Link to Item
-
Doraiswamy PM, Krishnan KR, O’Connor C, MacFall J. Cardiac disease and depression: A double hit on cerebral perfusion? American Journal of Geriatric Psychiatry. 2002 Mar 1;10(2):38–38.Link to Item
-
Doraiswamy PM, Leon J, Cummings JL, Marin D, Neumann PJ. Prevalence and impact of medical comorbidity in Alzheimer's disease. J Gerontol a Biol Sci Med Sci. 2002 Mar;57(3):M173–7.Full Text Link to Item
-
Doraiswamy PM. Does apolipoprotein E modulate human brain aging? American Journal of Geriatric Psychiatry. 2002 Mar 1;10(2):14–14.Link to Item
-
Doraiswamy PM. Science with a human face: Lessons from the Nun Study and Alzheimer's research. American Journal of Geriatric Psychiatry. 2002 Mar 1;10(2):20–20.Link to Item
-
Doraiswamy PM. Sleep in Alzheimer's disease: Do cholinergic drugs help or hurt? American Journal of Geriatric Psychiatry. 2002 Mar 1;10(2):23–23.Link to Item
-
Doraiswamy PM, Khan ZM, Donahue RMJ, Richard NE. The spectrum of quality-of-life impairments in recurrent geriatric depression. J Gerontol a Biol Sci Med Sci. 2002 Feb;57(2):M134–7.Full Text Link to Item
-
Chen JG, Edwards CL, Vidyarthi S, Pitchumoni S, Tabrizi S, Barboriak D, et al. Learning and recall in subjects at genetic risk for Alzheimer's disease. J Neuropsychiatry Clin Neurosci. 2002;14(1):58–63.Full Text Link to Item
-
Doraiswamy PM. Non-cholinergic strategies for treating and preventing Alzheimer's disease. Cns Drugs. 2002;16(12):811–24.Full Text Link to Item
-
Doraiswamy PM. The Alzheimer's disease assessment scale: Evaluation of psychometric properties and patterns of cognitive decline in multicenter clinical trials of mild to moderate Alzheimer's disease. Alzheimer Disease & Associated Disorders. 2002 Jan 1;16(1):48–48.Link to Item
-
Townsend BA, Petrella JR, Doraiswamy PM. The role of neuroimaging in geriatric psychiatry. Current Opinion in Psychiatry. 2002 Jan 1;15(4):427–32.Full Text
-
Doraiswamy. Erratum: (Alzheimer Disease and Associated Disorders (October/December 2001) (174)). Alzheimer Disease and Associated Disorders. 2002 Jan 1;16(1).Full Text
-
Petrella JR, Lustig C, Bucher LA, Jha AP, Doraiswamy PM. Prefrontal activation patterns in subjects at risk for Alzheimer disease. Am J Geriatr Psychiatry. 2002;10(1):112–3.Link to Item
-
Varia IM, Cloutier CA, Doraiswamy PM. Treatment of social anxiety disorder with citalopram. Prog Neuropsychopharmacol Biol Psychiatry. 2002 Jan;26(1):205–8.Full Text Link to Item
-
Wu LR, Parkerson GR, Doraiswamy PM. Health perception, pain, and disability as correlates of anxiety and depression symptoms in primary care patients. J Am Board Fam Pract. 2002;15(3):183–90.Link to Item
-
Van Meter SA, Seaburg H, McLendon B, Doraiswamy PM. Olanzapine, new-onset diabetes mellitus, and risk for insulin overdose. J Clin Psychiatry. 2001 Dec;62(12):993–4.Full Text Link to Item
-
Koller E, Malozowski S, Doraiswamy PM. Atypical antipsychotic drugs and hyperglycemia in adolescents. Jama. 2001 Nov 28;286(20):2547–8.Full Text Link to Item
-
Koller E, Malozowski S, Doraiswamy PM. Atypical antipsychotic drugs and hyperglycemia in adolescents [4] (multiple letters). Journal of the American Medical Association. 2001 Nov 28;286(20):2547–8.Full Text
-
Petrella JR, Lustig C, Bucher LA, Jha AP, Doraiswamy PM. Brain activation in patients at genetic risk for Alzheimer's disease: A pilot study using a functional MRI stress test. Radiology. 2001 Nov 1;221:614–614.Link to Item
-
Seaburg HL, McLendon BM, Doraiswamy PM. Olanzapine-associated severe hyperglycemia, ketonuria, and acidosis: case report and review of literature. Pharmacotherapy. 2001 Nov;21(11):1448–54.Full Text Link to Item
-
Steffens DC, Doraiswamy PM, McQuoid DR. Bupropion SR in the naturalistic treatment of elderly patients with major depression. Int J Geriatr Psychiatry. 2001 Sep;16(9):862–5.Full Text Link to Item
-
Doraiswamy PM, Scates AC. Relapse of depression after electroconvulsive therapy. Jama. 2001 Jun 27;285(24):3087–9.Link to Item
-
Glick ID, Janowsky DS, Zisook S, Lydiard RB, Oesterheld JR, Ward NG, et al. How should we teach psychopharmacology to residents? Results of the initial experience with the ASCP model curriculum. Academic Psychiatry. 2001 Jun 1;25(2):90–7.Full Text
-
Doraiswamy PM, Barboriak D, Krishnan KRR, Chen G, Smith J, Charles HC. Brain 1H-MR spectroscopy in subjects at risk for Alzheimer's disease. Neurobiology of Aging. 2001 Mar 1;22(2):336–7.Link to Item
-
Petrella JR, Bucher L, Jha A, Doraiswamy PM, McCarthy G. Event-related functional MRI for the early diagnosis of Alzheimer disease: A pilot study in normal volunteers and patients with mild cognitive impairment. Neurobiology of Aging. 2001 Mar 1;22(2):338–338.Link to Item
-
Krishnan KR, Doraiswamy PM, Clary CM. Clinical and treatment response characteristics of late-life depression associated with vascular disease: a pooled analysis of two multicenter trials with sertraline. Prog Neuropsychopharmacol Biol Psychiatry. 2001 Feb;25(2):347–61.Full Text Link to Item
-
Doraiswamy PM. Contemporary management of comorbid anxiety and depression in geriatric patients. J Clin Psychiatry. 2001;62 Suppl 12:30–5.Link to Item
-
Krishnan KR, Levy RM, Wagner HR, Chen G, Gersing K, Doraiswamy PM. Informant-rated cognitive symptoms in normal aging, mild cognitive impairment, and dementia. Initial development of an informant-rated screen (Brief Cognitive Scale) for mild cognitive impairment and dementia. Psychopharmacol Bull. 2001;35(3):79–88.Link to Item
-
Blumenthal JA, Hart A, Sherwood A, Doraiswamy M, Herman S, Watkins L, et al. Depression and vascular function in older adults. Evaluating the benefits of exercise in a new study at Duke University. N C Med J. 2001;62(2):95–8.Link to Item
-
Doraiswamy PM, Kaiser L, Bieber F, Garman RL. The Alzheimer's Disease Assessment Scale: evaluation of psychometric properties and patterns of cognitive decline in multicenter clinical trials of mild to moderate Alzheimer's disease. Alzheimer Dis Assoc Disord. 2001;15(4):174–83.Full Text Link to Item
-
Doraiswamy PM, Khan ZM, Donahue RM, Richard NE. Quality of life in geriatric depression: a comparison of remitters, partial responders, and nonresponders. Am J Geriatr Psychiatry. 2001;9(4):423–8.Link to Item
-
Khatri P, Blumenthal JA, Babyak MA, Craighead WE, Herman S, Baldewicz T, et al. Effects of exercise training on cognitive functioning among depressed older men and women. Journal of Aging and Physical Activity. 2001 Jan 1;9(1):43–57.Full Text
-
Kishnani PS, Spiridigliozzi GA, Heller JH, Sullivan JA, Doraiswamy PM, Krishnan KR. Donepezil for Down's syndrome. Am J Psychiatry. 2001 Jan;158(1):143.Full Text Link to Item
-
Nangia M, Syed W, Doraiswamy PM. Efficacy and safety of St. John's wort for the treatment of major depression. Public Health Nutr. 2000 Dec;3(4A):487–94.Full Text Link to Item
-
Newhouse PA, Krishnan KRR, Doraiswamy PM. A double-blind comparison of sertraline and fluoxetine in depressed elderly patients. Primary Care Companion to the Journal of Clinical Psychiatry. 2000 Dec 1;2(4):149.
-
Petrella JR, Bucher LA, Doraiswamy PM, Jha AP, Provenzale JM, McCarthy G. Cortical activation differences between patients with mild cognitive impairment and older normal subjects during a working memory task: An event-related fMRI study. Radiology. 2000 Nov 1;217:552–552.Link to Item
-
Scates AC, Doraiswamy PM. Reboxetine: a selective norepinephrine reuptake inhibitor for the treatment of depression. Ann Pharmacother. 2000 Nov;34(11):1302–12.Full Text Link to Item
-
Varia I, O’Connor C, Gersing K, Doraiswamy PM, Brown K, Fortner M. Effect of bupropion SR on the quality of life of elderly depressed patients with medical comorbidity: Preliminary findings. Journal of the American Geriatrics Society. 2000 Aug 1;48(8):S13–S13.Link to Item
-
Newhouse PA, Krishnan KR, Doraiswamy PM, Richter EM, Batzar ED, Clary CM. A double-blind comparison of sertraline and fluoxetine in depressed elderly outpatients. J Clin Psychiatry. 2000 Aug;61(8):559–68.Full Text Link to Item
-
Barboriak DP, Doraiswamy PM, Krishnan KR, Vidyarthi S, Sylvester J, Charles HC. Hippocampal sulcal cavities on MRI: relationship to age and apolipoprotein E genotype. Neurology. 2000 Jun 13;54(11):2150–3.Full Text Link to Item
-
Murali Doraiswamy P, Kaiser L. Variability of the mini-mental state examination in dementia. Neurology. 2000 Apr 11;54(7):1538–9.Full Text Link to Item
-
McLendon BM, Chen GG, Doraiswamy PM. Current and future treatments for cognitive deficits in dementia. Curr Psychiatry Rep. 2000 Feb;2(1):20–3.Full Text Link to Item
-
Chen JG, Charles HC, Barboriak DP, Doraiswamy PM. Magnetic resonance spectroscopy in Alzheimer's disease: focus on N-acetylaspartate. Acta Neurol Scand Suppl. 2000;176:20–6.Full Text Link to Item
-
Doraiswamy PM, Chen JG, Charles HC. Brain magnetic resonance spectroscopy: Role in assessing outcomes in Alzheimer's disease. Cns Drugs. 2000 Jan 1;14(6):457–72.Full Text
-
Leon J, Neumann PJ, Hermann RC, Hsu MA, Cummings JL, Doraiswamy PM, et al. Health-related quality-of-life and service utilization in Alzheimer's disease: A cross-sectional study. American Journal of Alzheimer’S Disease and Other Dementias. 2000 Jan 1;15(2):94–108.Full Text
-
Babyak M, Blumenthal JA, Herman S, Khatri P, Doraiswamy M, Moore K, et al. Exercise treatment for major depression: maintenance of therapeutic benefit at 10 months. Psychosom Med. 2000;62(5):633–8.Full Text Link to Item
-
Fortner MR, Brown K, Varia IM, Gersing KR, O’Connor C, Doraiswamy PM. Effect of Bupropion SR on the Quality of Life of Elderly Depressed Patients With Comorbid Medical Disorders. Prim Care Companion J Clin Psychiatry. 1999 Dec;1(6):174–9.Full Text Link to Item
-
Blumenthal JA, Babyak MA, Moore KA, Craighead WE, Herman S, Khatri P, et al. Effects of exercise training on older patients with major depression. Arch Intern Med. 1999 Oct 25;159(19):2349–56.Full Text Link to Item
-
Doraiswamy PM, MacFall J, Krishnan KR, O’Connor C, Wan X, Benaur M, et al. Magnetic resonance assessment of cerebral perfusion in depressed cardiac patients: preliminary findings. Am J Psychiatry. 1999 Oct;156(10):1641–3.Full Text Link to Item
-
Kishnani PS, Sullivan JA, Walter BK, Spiridigliozzi GA, Doraiswamy PM, Krishnan KR. Cholinergic therapy for Down's syndrome. Lancet. 1999 Mar 27;353(9158):1064–5.Full Text Link to Item
-
McLendon BM, Doraiswamy PM. Defining meaningful change in Alzheimer's disease trials: the donepezil experience. J Geriatr Psychiatry Neurol. 1999;12(1):39–48.Full Text Link to Item
-
Blumenthal JA, Babyak M, Moore K, Craighead E, Herman S, Khatri P, et al. EXERCISE TRAINING AND MAJOR DEPRESSION. Psychosomatic Medicine. 1999;61(1):124–5.Full Text
-
Pitchumoni SS, Doraiswamy PM. Current status of antioxidant therapy for Alzheimer's Disease. J Am Geriatr Soc. 1998 Dec;46(12):1566–72.Full Text Link to Item
-
Scates AC, Doraiswamy PM. Focus on citalopram: A selective reuptake inhibitor for the treatment of depression. Formulary. 1998 Dec 1;33(8):725–43.
-
Doraiswamy PM, Charles HC, Krishnan KR. Prediction of cognitive decline in early Alzheimer's disease. Lancet. 1998 Nov 21;352(9141):1678.Full Text Link to Item
-
Garges HP, Varia I, Doraiswamy PM. Cardiac complications and delirium associated with valerian root withdrawal. Jama. 1998 Nov 11;280(18):1566–7.Full Text Link to Item
-
Doraiswamy PM, Steffens DC. Combination therapy for early Alzheimer's disease: what are we waiting for? J Am Geriatr Soc. 1998 Oct;46(10):1322–4.Full Text Link to Item
-
Leon J, Neumann PJ, Hermann RC, Hsu MA, Cummings JL, Marin D, et al. A cross sectional study on the health related quality of life and health service utilization for mild, moderate, and severely impaired Alzheimer's disease patients. Neurology. 1998 Apr 1;50(4):A303–A303.Link to Item
-
Doraiswamy PM, Steffens DC, Pitchumoni S, Tabrizi S. Early recognition of Alzheimer's disease: what is consensual? What is controversial? What is practical? J Clin Psychiatry. 1998;59 Suppl 13:6–18.Link to Item
-
Gersing KR, Doraiswamy PM, Krishana KRR. Vascular dementia: The end stage of cerebral vascular disease. Current Opinion in Psychiatry. 1998 Jan 1;11(4):425–9.Full Text
-
Doraiswamy PM, Krishen A, Martin WL, Sylvester J, Garman RL, Metz A, et al. Gender, concurrent estrogen use and cognition in Alzheimer's disease. International Journal of Geriatric Psychopharmacology. 1997 Dec 1;1(1):34–7.
-
Doraiswamy PM, Bieber F, Kaiser L, Krishnan KR, Reuning-Scherer J, Gulanski B. The Alzheimer's Disease Assessment Scale: patterns and predictors of baseline cognitive performance in multicenter Alzheimer's disease trials. Neurology. 1997 Jun;48(6):1511–7.Full Text Link to Item
-
Doraiswamy PM, Bieber F, Kaiser L, Gulanski B. The Alzheimer's disease assessment scale .6. Noncognitive signs and symptoms in outpatients with Alzheimer's disease. Psychopharmacology Bulletin. 1997 Jan 1;33(3):514–514.Link to Item
-
Doraiswamy PM, Bieber F, Kaiser L, Connors K, Krishnan KR, Reuning-Scherer J, et al. Memory, language, and praxis in Alzheimer's disease: norms for outpatient clinical trial populations. Psychopharmacol Bull. 1997;33(1):123–8.Link to Item
-
Gonzalez MB, Cousins JC, Doraiswamy PM. Neurobiology of chronic fatigue syndrome. Prog Neuropsychopharmacol Biol Psychiatry. 1996 Jul;20(5):749–59.Full Text Link to Item
-
Doraiswamy PM, Krishen A, Stallone F, Martin WL, Potts NL, Metz A, et al. NSAIDs and cognition in Alzheimer's disease. Neurology. 1996 Apr;46(4):1194.Full Text Link to Item
-
Kumar V, Goldstein MZ, Doraiswamy PM. Advances in pharmacotherapy for decline of memory and cognition in patients with Alzheimer's disease. Psychiatr Serv. 1996 Mar;47(3):249–53.Full Text Link to Item
-
Doraiswamy PM, Bieber F, ReuningScherer J, Krishnan KR, Kaiser L, Gulenski B. The Alzheimer's Disease Assessment Scale: Predictors of baseline cognitive performance in clinical trials. Psychopharmacology Bulletin. 1996 Jan 1;32(3):434–434.Link to Item
-
Doraiswamy PM, Krishen A, Stallone F, Martin WL, Potts NL, Metz A, et al. Cognitive performance on the Alzheimer's Disease Assessment Scale: effect of education. Neurology. 1995 Nov;45(11):1980–4.Full Text Link to Item
-
Doraiswamy M, Martin W, Metz A, Deveaugh-Geiss J. Psychosis in Parkinson's disease: diagnosis and treatment. Prog Neuropsychopharmacol Biol Psychiatry. 1995 Sep;19(5):835–46.Full Text Link to Item
-
Doraiswamy PM, Tupler LA, Krishnan KR. Neuroleptic treatment and caudate plasticity. Lancet. 1995 Mar 18;345(8951):734–5.Link to Item
-
DORAISWAMY PM. POSSIBLE SEASONAL-CHANGES IN PITUITARY SIZE - COMMENT. American Journal of Neuroradiology. 1995 Jan 1;16(1):215–215.Link to Item
-
Halpern SD, Doraiswamy PM, Tupler LA, Holland JM, Ford SM, Ellinwood EH. Emergency department patterns in psychiatric visits during the holiday season. Ann Emerg Med. 1994 Nov;24(5):939–43.Full Text Link to Item
-
Charles HC, Lazeyras F, Krishnan KR, Boyko OB, Patterson LJ, Doraiswamy PM, et al. Proton spectroscopy of human brain: effects of age and sex. Prog Neuropsychopharmacol Biol Psychiatry. 1994 Oct;18(6):995–1004.Full Text Link to Item
-
Kamran A, Doraiswamy PM, Jane JL, Hammett EB, Dunn L. Severe hyperglycemia associated with high doses of clozapine. Am J Psychiatry. 1994 Sep;151(9):1395.Full Text Link to Item
-
Potts NL, Davidson JR, Krishnan KR, Doraiswamy PM. Magnetic resonance imaging in social phobia. Psychiatry Res. 1994 Apr;52(1):35–42.Full Text Link to Item
-
Doraiswamy PM, Massey EW, Enright K, Palese VJ, Lamonica D, Boyko O. Wernicke-Korsakoff syndrome caused by psychogenic food refusal: MR findings. Ajnr Am J Neuroradiol. 1994 Mar;15(3):594–6.Link to Item
-
Rajagopalan P, Passe TJ, Doraiswamy PM, Figiel GS, Macfall JR, Krishnan KR. Changes in pituitary gland signal intensity and morphology as evaluated by magnetic resonance imaging in aging, depression, and by gender. Depression. 1994 Jan 1;2(6):303–7.Full Text
-
Doraiswamy PM, Patterson L, Na C, Husain MM, Boyko O, McDonald WM, et al. Bicaudate index on magnetic resonance imaging: effects of normal aging. J Geriatr Psychiatry Neurol. 1994;7(1):13–7.Link to Item
-
Holmes VF, D’Alli R, Schweickert L, White R, Brown T, Doraiswamy M, et al. Vitamin E treatment of tardive dyskinesia. Am J Psychiatry. 1993 Jun;150(6):991.Link to Item
-
Axelson DA, Doraiswamy PM, McDonald WM, Boyko OB, Tupler LA, Patterson LJ, et al. Hypercortisolemia and hippocampal changes in depression. Psychiatry Res. 1993 May;47(2):163–73.Full Text Link to Item
-
Doraiswamy PM, Reeder KP, Logue PE, Husain MM, Figiel GS, Krishnan KRR, et al. MRI detection of abnormality in the corpus callosum and late‐onset depression. Depression. 1993 Jan 1;1(2):108–9.Full Text
-
Escalona PR, Early B, McDonald WM, Doraiswamy PM, Shah SA, Husain MM, et al. Reduction of cerebellar volume in major depression: A controlled MRI study. Depression. 1993 Jan 1;1(3):156–8.Full Text
-
Lisanby SH, McDonald WM, Massey EW, Doraiswamy PM, Rozear M, Boyko OB, et al. Diminished subcortical nuclei volumes in Parkinson's disease by MR imaging. J Neural Transm Suppl. 1993;40:13–21.Link to Item
-
Doraiswamy PM, McDonald WM, Patterson L, Husain MM, Figiel GS, Boyko OB, et al. Interuncal distance as a measure of hippocampal atrophy: normative data on axial MR imaging. Ajnr Am J Neuroradiol. 1993;14(1):141–3.Link to Item
-
Early B, Escalona PR, Boyko OB, Doraiswamy PM, Axelson DA, Patterson L, et al. Interuncal distance measurements in healthy volunteers and in patients with Alzheimer disease. Ajnr Am J Neuroradiol. 1993;14(4):907–10.Link to Item
-
Krishnan KR, McDonald WM, Doraiswamy PM, Tupler LA, Husain M, Boyko OB, et al. Neuroanatomical substrates of depression in the elderly. Eur Arch Psychiatry Clin Neurosci. 1993;243(1):41–6.Full Text Link to Item
-
Axelson DA, Doraiswamy PM, Boyko OB, Rodrigo Escalona P, McDonald WM, Ritchie JC, et al. In vivo assessment of pituitary volume with magnetic resonance imaging and systematic stereology: relationship to dexamethasone suppression test results in patients. Psychiatry Res. 1992 Oct;44(1):63–70.Full Text Link to Item
-
Krishnan KR, McDonald WM, Escalona PR, Doraiswamy PM, Na C, Husain MM, et al. Magnetic resonance imaging of the caudate nuclei in depression. Preliminary observations. Arch Gen Psychiatry. 1992 Jul;49(7):553–7.Full Text Link to Item
-
Shah SA, Doraiswamy PM, Husain MM, Escalona PR, Na C, Figiel GS, et al. Posterior fossa abnormalities in major depression: a controlled magnetic resonance imaging study. Acta Psychiatr Scand. 1992 Jun;85(6):474–9.Full Text Link to Item
-
Husain MM, Black KJ, Doraiswamy PM, Shah SA, Rockwell WJ, Ellinwood EH, et al. Subcortical brain anatomy in anorexia and bulimia. Biol Psychiatry. 1992 Apr 1;31(7):735–8.Full Text Link to Item
-
Figiel GS, Botteron K, Zorumski CF, Jarvis MR, Doraiswamy M, Krishnan R. The treatment of late age onset psychoses with electroconvulsive therapy. International Journal of Geriatric Psychiatry. 1992;7(3):183–9.
-
Figiel GS, Zorumski CF, Doraiswamy PM, Mattingly GW, Jarvis MR. Simultaneous major depression and panic disorder: treatment with electroconvulsive therapy. J Clin Psychiatry. 1992 Jan;53(1):12–5.Link to Item
-
Doraiswamy PM, Na C, Husain MM, Figiel GS, McDonald WM, Ellinwood EH, et al. Morphometric changes of the human midbrain with normal aging: MR and stereologic findings. Ajnr Am J Neuroradiol. 1992;13(1):383–6.Link to Item
-
Doraiswamy PM, Potts JM, Axelson DA, Husain MM, Lurie SN, Na C, et al. MR assessment of pituitary gland morphology in healthy volunteers: age- and gender-related differences. Ajnr Am J Neuroradiol. 1992;13(5):1295–9.Link to Item
-
Krishnan KRR. A magnetic resonance imaging study of putamen nuclei in major depression. Psychiatry Research. 1991 Dec 1;40(2):95–9.Full Text
-
McDonald WM, Krishnan KR, Doraiswamy PM, Blazer DG. Occurrence of subcortical hyperintensities in elderly subjects with mania. Psychiatry Res. 1991 Dec;40(4):211–20.Full Text Link to Item
-
Potts NL, Davidson JR, Krishnan KR, Doraiswamy PM, Ritchie JC. Levels of urinary free cortisol in social phobia. J Clin Psychiatry. 1991 Nov;52 Suppl:41–2.Link to Item
-
Doraiswamy PM, Escalona PR, Shah SA, Husain MM, Figiel GS, Krishnan KR. Magnetic resonance imaging (MRI)--morphometric study. J Child Neurol. 1991 Oct;6(4):372.Full Text Link to Item
-
Husain MM, McDonald WM, Doraiswamy PM, Figiel GS, Na C, Escalona PR, et al. A magnetic resonance imaging study of putamen nuclei in major depression. Psychiatry Res. 1991 Oct;40(2):95–9.Full Text Link to Item
-
Murali Doraiswamy P, Rodrigo Escalona P, Krishnan KR, Husain MM, Figiel GS. MRI quantification. Neurology. 1991 Jun;41(6):954–5.Full Text Link to Item
-
Murali Doraiswamy P, Rodrigo Escalona P, Krishnan KR, Husain MM, Figiel GS. MRI quantification. Neurology. 1991 Jun 1;41(6):954–5.
-
Doraiswamy PM, Axelson DA, Escalona PR, Shah SA, Husain MM, Figiel GS, et al. Magnetic resonance imaging in idiopathic hypopituitarism. Eur J Pediatr. 1991 Jun;150(8):600.Full Text Link to Item
-
Magnetic resonance imaging hyperintensities in Alzheimer's disease. Arch Neurol. 1991 May;48(5):468–70.Link to Item
-
McDonald WM, Krishnan KR, Doraiswamy PM, Figiel GS, Husain MM, Boyko OB, et al. Magnetic resonance findings in patients with early-onset Alzheimer's disease. Biol Psychiatry. 1991 Apr 15;29(8):799–810.Full Text Link to Item
-
Doraiswamy PM, Shah SA, Husain MM, Rodrigo Escalona P, McDonald WM, Figiel GS, et al. Magnetic resonance evaluation of the midbrain in Parkinson's disease. Arch Neurol. 1991 Apr;48(4):360.Full Text Link to Item
-
Husain MM, Knight DL, Doraiswamy PM, Figiel GS, McDonald WM, Boyko OB, et al. Platelet [3H]-imipramine binding and leukoencephalopathy in geriatric depression. Biol Psychiatry. 1991 Apr 1;29(7):665–70.Full Text Link to Item
-
Doraiswamy PM, Krishnan KR, Nemeroff CB. Neuropeptides and neurotransmitters in Alzheimer's disease: focus on corticotrophin releasing factor. Baillieres Clin Endocrinol Metab. 1991 Mar;5(1):59–77.Full Text Link to Item
-
Krishnan KR, Doraiswamy PM, Lurie SN, Figiel GS, Husain MM, Boyko OB, et al. Pituitary size in depression. J Clin Endocrinol Metab. 1991 Feb;72(2):256–9.Full Text Link to Item
-
Lammers CH, Doraiswamy PM, Husain MM, Figiel GS, Lurie SN, Boyko OB, et al. MRI of corpus callosum and septum pellucidum in depression. Biol Psychiatry. 1991 Feb 1;29(3):300–1.Full Text Link to Item
-
Doraiswamy PM, Figiel GS, Husain MM, McDonald WM, Shah SA, Boyko OB, et al. Aging of the human corpus callosum: magnetic resonance imaging in normal volunteers. J Neuropsychiatry Clin Neurosci. 1991;3(4):392–7.Full Text Link to Item
-
Figiel GS, Hassen MA, Zorumski C, Krishnan KR, Doraiswamy PM, Jarvis MR, et al. ECT-induced delirium in depressed patients with Parkinson's disease. J Neuropsychiatry Clin Neurosci. 1991;3(4):405–11.Full Text Link to Item
-
Figiel GS, Krishnan KR, Rao VP, Doraiswamy M, Ellinwood EH, Nemeroff CB, et al. Subcortical hyperintensities on brain magnetic resonance imaging: a comparison of normal and bipolar subjects. J Neuropsychiatry Clin Neurosci. 1991;3(1):18–22.Full Text Link to Item
-
Krishnan KR, Doraiswamy PM, Figiel GS, Husain MM, Shah SA, Na C, et al. Hippocampal abnormalities in depression. J Neuropsychiatry Clin Neurosci. 1991;3(4):387–91.Full Text Link to Item
-
McDonald WM, Husain M, Doraiswamy PM, Figiel G, Boyko O, Krishnan KR. A magnetic resonance image study of age-related changes in human putamen nuclei. Neuroreport. 1991 Jan;2(1):57–60.Full Text Link to Item
-
Na C, Doraiswamy PM, Lee KH, Krishnan KR. Magnetic resonance imaging in biological psychiatry. Prog Neuropsychopharmacol Biol Psychiatry. 1991;15(5):581–93.Full Text Link to Item
-
Doraiswamy PM, Krishnan KR, Boyko OB, Husain MM, Figiel GS, Palese VJ, et al. Pituitary abnormalities in eating disorders: further evidence from MRI studies. Prog Neuropsychopharmacol Biol Psychiatry. 1991;15(3):351–6.Full Text Link to Item
-
Doraiswamy PM, Potts JM, Figiel GS, Boyko OB, Krishnan KR. MR imaging of physiologic pituitary gland hypertrophy in adolescence. Radiology. 1991 Jan;178(1):284–5.Full Text Link to Item
-
Escalona PR, McDonald WM, Doraiswamy PM, Boyko OB, Husain MM, Figiel GS, et al. In vivo stereological assessment of human cerebellar volume: effects of gender and age. Ajnr Am J Neuroradiol. 1991;12(5):927–9.Link to Item
-
Figiel GS, Krishnan KR, Doraiswamy PM, Nemeroff CB. Caudate hyperintensities in elderly depressed patients with neuroleptic-induced parkinsonism. J Geriatr Psychiatry Neurol. 1991;4(2):86–9.Full Text Link to Item
-
Figiel GS, Krishnan KR, Doraiswamy PM, Rao VP, Nemeroff CB, Boyko OB. Subcortical hyperintensities on brain magnetic resonance imaging: a comparison between late age onset and early onset elderly depressed subjects. Neurobiol Aging. 1991;12(3):245–7.Full Text Link to Item
-
Shah SA, Doraiswamy PM, Husain MM, Figiel GS, Boyko OB, McDonald WM, et al. Assessment of posterior fossa structures with midsagittal MRI: the effects of age. Neurobiol Aging. 1991;12(4):371–4.Full Text Link to Item
-
DORAISWAMY PM, HUSAIN MM, FIGIEL GS, SHAH SA, MCDONALD WM, BOYKO OB, et al. MAGNETIC-RESONANCE-IMAGING OF THE HUMAN CORPUS-CALLOSUM - SEX-DIFFERENCES AND NORMAL AGING. Annals of Neurology. 1990 Aug 1;28(2):259–259.Link to Item
-
Lurie SN, Doraiswamy PM, Husain MM, Boyko OB, Ellinwood EH, Figiel GS, et al. In vivo assessment of pituitary gland volume with magnetic resonance imaging: the effect of age. J Clin Endocrinol Metab. 1990 Aug;71(2):505–8.Full Text Link to Item
-
Doraiswamy PM, Krishnan KR, Figiel GS, Husain MM, Boyko OB, Rockwell WJ, et al. A brain magnetic resonance imaging study of pituitary gland morphology in anorexia nervosa and bulimia. Biol Psychiatry. 1990 Jul 15;28(2):110–6.Full Text Link to Item
-
Figiel GS, Coffey CE, Djang WT, Hoffman G, Doraiswamy PM. Brain magnetic resonance imaging findings in ECT-induced delirium. J Neuropsychiatry Clin Neurosci. 1990;2(1):53–8.Full Text Link to Item
-
Figiel GS, Krishnan KR, Doraiswamy PM. Subcortical structural changes in ECT-induced delirium. J Geriatr Psychiatry Neurol. 1990;3(3):172–6.Full Text Link to Item
-
Krishnan KR, Husain MM, McDonald WM, Doraiswamy PM, Figiel GS, Boyko OB, et al. In vivo stereological assessment of caudate volume in man: effect of normal aging. Life Sci. 1990;47(15):1325–9.Full Text Link to Item
-
-
Conference Papers
-
Devanand DP, Reynolds CF, Pelton GH, Doraiswamy PM, Mulsant BH, Morimoto SS, et al. Therapeutic Strategies in Depression with Cognitive Impairment. In: The American Journal of Geriatric Psychiatry. Elsevier BV; 2018. p. S18–20.Full Text
-
Harenberg S, Seay RG, Bello GA, Chirkova RY, Doraiswamy PM, Samatova NF. Knowledge-guided maximal clique enumeration. In: Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 2016. p. 604–18.Full Text
-
Doraiswamy PM, Pakhalchuk T, SanRamon G, Rechitsky S. Preimplantation Genetic Diagnosis (PGD) for Familial Alzheimer's Disease Due To PSEN1 Mutation. In: Annals of Neurology. WILEY-BLACKWELL; 2014. p. S90–S90.Link to Item
-
Hochstetler H, Doraiswamy PM, Sperling RA, Johnson KA, Reiman E, Sabbagh MN, et al. Relationship of Florbetapir F18 PET Amyloid Plaque Neuroimaging with Future Cognitive Decline over 36 Months. In: The American Journal of Geriatric Psychiatry. Elsevier BV; 2013. p. S136–S136.Full Text
-
Witte M, Dugger B, Serrano G, Bedell BJ, Doraiswamy PM, Fleisher AS, et al. Florbetapir PET Imaging Predicts Postmortem Amyloid Burden in Alzheimer's Disease Despite Presence of Other Neuropathologies. In: The American Journal of Geriatric Psychiatry. Elsevier BV; 2013. p. S138–9.Full Text
-
Sheldon FC, Petrella J, Doraiswamy PM. Disruption of Functional Brain Connections in Alzheimer's Disease. In: Journal of Nuclear Medicine. SOC NUCLEAR MEDICINE INC; 2010. p. 828–9.Link to Item
-
Doraiswamy PM, Coleman RE, Petrella JR, Sheldon F, Pontecorvo MJ, Hefti F, et al. In Cognitively Healthy and Mildly Impaired Individuals Florbetapir F 18 PET Measures of Amyloid Deposition Correlate with the Degree of Functional Impairment Assessed Six Months Later. In: Neurology. LIPPINCOTT WILLIAMS & WILKINS; 2010. p. A338–A338.Link to Item
-
Doraiswamy PM, Arani RA, Gan D, Pikalov A, Tran Q-V, Mankoski R, et al. Atypical antipsychotic drugs and diabetes mellitus in the USFDA adverse event reporting system (AERS) database in pediatric and adult patients. In: Biological Psychiatry. ELSEVIER SCIENCE INC; 2008. p. 283S-284S.Link to Item
-
Kaddurah-Daouk R, McEvoy J, Baillie RA, Yao JK, Doraiswamy PM, Krishnan KRR. Metabolomic mapping of schizophrenia and atypical antipsychotic effects. In: Biological Psychiatry. ELSEVIER SCIENCE INC; 2007. p. 164S-164S.Link to Item
-
Szarfman A, Tonning JM, Levine JG, Doraiswamy PM. Risperidone and pituitary tumors: a pharmacovigilance study. In: Bipolar Disorders. BLACKWELL PUBLISHING; 2005. p. 116–7.Link to Item
-
Pomara N, Doraiswamy PM, Willoughby LM, Metha PD, Pollock BG. Elevated plasma A beta(1-42) in geriatric depression. In: Biological Psychiatry. ELSEVIER SCIENCE INC; 2005. p. 200S-200S.Link to Item
-
Feldman H, Schmitt FA, Doraiswamy PM, Graham SM, Bell JM. Memantine and individual activities of daily living in moderate to severe Alzheimer's disease. In: Neurology. LIPPINCOTT WILLIAMS & WILKINS; 2005. p. A103–4.Link to Item
-
Kishnani PS, Spiridigliozzi GA, Heller JH, Sullivan JA, Crissman BG, Hauser E, et al. Randomized, double-blind, placebo-controlled crossover study of donepezil in Down syndrome. In: Neurology. LIPPINCOTT WILLIAMS & WILKINS; 2005. p. A106–A106.Link to Item
-
Pomara N, Doraiswamy PM, Willoughby L, Mehta PD, Pollock BG. Plasma amyloid beta 1-42 levels in geriatric depression: A pilot study. In: Neuropsychopharmacology. NATURE PUBLISHING GROUP; 2004. p. S202–S202.Link to Item
-
Doraiswamy PM, Steffens D, McQuoid D. O1-02-08 Statin use and hippocampal volume in subjects at risk for Alzheimer's disease. In: Neurobiology of Aging. Elsevier BV; 2004. p. S13–S13.Full Text
-
Doraiswamy PM, Taylor DH, Sloan FA. P2-249 Marked increase in Alzheimer's disease identified in medicare claims records between 1991 and 1999. In: Neurobiology of Aging. Elsevier BV; 2004. p. S303–S303.Full Text
-
Krishnan S, Slavin MJ, Tran T-T, Murty L, Finefrock AE, Doraiswamy PM, et al. P2-189 Comparison of FMRI activation patterns in mild cognitive impairment (MCI) subjects and elderly controls at ultra-high field strength. In: Neurobiology of Aging. Elsevier BV; 2004. p. S281–2.Full Text
-
Pericak-Vance MA, Bronson P, Martin ER, Browning C, Rayner M, Xu P, et al. P4-080 Genetic studies of Alzheimer disease on chromosome 9P. In: Neurobiology of Aging. Elsevier BV; 2004. p. S497–S497.Full Text
-
Taylor DH, Doraiswamy PM, Sloan FA. P4-041 Rates of diagnosis of vascular dementia over 10 years in the United States medicare claims records. In: Neurobiology of Aging. Elsevier BV; 2004. p. S484–S484.Full Text
-
KRISHNAN KRR, DORAISWAMY PM, AXELSON DA, LURIE SN, FIGIEL GS, HUSAIN MM, et al. PITUITARY CHANGES IN DEPRESSION. In: RACAGNI G, BRUNELLO N, FUKUDA T, editors. Biological Psychiatry, Vol 1. ELSEVIER SCIENCE PUBL B V; 1991. p. 213–6.Link to Item
-
-
- Teaching & Mentoring
-
Recent Courses
Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.