Research Interests
Precision Medicine
Digital Therapeutics
Biomarkers
Clinical Trials
Aging
Artificial Intelligence in Medicine
Digital Therapeutics
Biomarkers
Clinical Trials
Aging
Artificial Intelligence in Medicine
Selected Grants
Duke University Psychiatry Physician-Scientist Residency Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2024 - 2029Cognitive training and neuroplasticity in Mild Cognitive Impairment
ResearchPrincipal Investigator · Awarded by Columbia University · 2017 - 2029Utility of blood biomarkers for predicting ARIA and its course in MCI and AD subjects undergoing routine clinical treatment
ResearchPrincipal Investigator · Awarded by Cure Alzheimer's Fund · 2024 - 2026Duke Creating ADRD Researchers for the Next Generation - Stimulating Access to Research in Residency Program (CARiNG-StARR)"
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2020 - 2025Metabolomic Signatures for Disease Sub-classification and Target Prioritization in AMP-AD
ResearchCo Investigator · Awarded by National Institutes of Health · 2018 - 2025FORD0120-45157 - Alzheimer's Disease Neuroimaging Initiative (ADNI4) Supplement
ResearchPrincipal Investigator · Awarded by Fordham University · 2023 - 2025Alzheimer's Disease Neuroimaging Initiative (ADNI4)
ResearchPrincipal Investigator · Awarded by University of Southern California · 2022 - 2025Racial and Geographic Disparities in Risk and Survival of Alzheimer's Disease and Related Dementias: Effects of Over/UnderDiagnosis and Disease Severity
ResearchSenior Investigator · Awarded by National Institutes of Health · 2019 - 2025Genetic Modulations of Morbidity Compression: A Population-Based Study
ResearchInvestigator · Awarded by National Institute on Aging · 2020 - 2025Sex Differences in Alzheimer's Disease Progression: Framingham Heart Study
ResearchPrincipal Investigator · Awarded by Cure Alzheimer's Fund · 2021 - 2024Evaluating Effects in the Relationship between Traumatic Brain Injury and Alzheimer's Disease: Epidemiological Determinants, Their Health-Related Causes and the Resulting Disparities
ResearchSenior Investigator · Awarded by United States Army Medical Research Acquisition Activity · 2020 - 2024Impact of Midlife and Late-Life Intake of Flavonoid-Rich Fruits on Dementia Risk in the Framingham Heart Study
ResearchPrincipal Investigator · Awarded by Boston University · 2022 - 2024Blueberry supplementation effects in Subjects at Risk for Alzheimer's Disease
ResearchPrincipal Investigator · Awarded by U.S. Highbush Blueberry Council · 2022 - 2024Cognitive Training and Neuroplasticity in Mild Cognitive Impairment
ResearchPrincipal Investigator · Awarded by The Trustees of Columbia University · 2020 - 2024Gut Liver Brain Biochemical Axis in Alzheimer's Disease
ResearchCo Investigator · Awarded by National Institutes of Health · 2018 - 2023Metabolic Networks and Pathways Predictive of Sex Differences in AD Risk and Responsiveness to Treatment
ResearchCo Investigator · Awarded by National Institutes of Health · 2018 - 2023Phase 3 Clinical Trial for Agitation in Alzheimer's 15-AVP-786-303
ResearchPrincipal Investigator · Awarded by Avanir Pharmaceuticals · 2016 - 2023Phase 3 Clinical Trial for Agitation in Alzheimer's 15-AVP-786-301
ResearchPrincipal Investigator · Awarded by Avanir Pharmaceuticals · 2016 - 2023ADNI-3 Diversity Supplement
ResearchPrincipal Investigator · Awarded by University of Southern California · 2020 - 2022Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3)
ResearchPrincipal Investigator · Awarded by University of Southern California · 2016 - 2022Does rifaximin improve cognition in patients with Alzheimer's disease?" using Manufacturer's drug XIFAXAN
Clinical TrialCo Investigator · Awarded by Bausch Health US LLC · 2019 - 2022The Role of the Gut Microbiome and Metabolome in Alzheimer's Disease
ResearchCo Investigator · Awarded by North Carolina Biotechnology Center · 2021 - 2021Effects of Traumatic Brain Injury and Post-Traumatic Stress Disorder and Alzheimer's Disease on Brain Tau in Vietnam Veterans using ADNI
ResearchPrincipal Investigator · Awarded by University of Southern California · 2016 - 2021Predicting prebiotic effects on human microbiota, behavior, and cognition.
ResearchCollaborator · Awarded by Office of Naval Research · 2018 - 2021A Clinical-Pathological Study of the Correspondence Between 18F-AV-1451 PET Imaging and Post-Mortem Assessment of Tau Pathology
Clinical TrialPrincipal Investigator · Awarded by Avid Radiopharmaceuticals Inc · 2015 - 2021High Resolution Intracortical DTI for Early Detection of Alzheimer¿s Disease
ResearchCo Investigator · Awarded by Neuroradiology Education and Reserach Foundation (formerly Foundation of the ASNR) · 2016 - 2020Effects of Traumatic Brain Injury (TBI) and Post Traumatic Stress Disorder (PTSD) on Alzheimer's Disease (AD) in Veterans Using Imaging and Biomarkers in the AD Neuroimaging Initiative (ADNI) (DoD)
Clinical TrialPrincipal Investigator · Awarded by University of Southern California · 2015 - 2020Effects of Traumatic Brain Injury and Post-Traumatic Stress Disorder on Alzheimer's Disease (AD) in Veterans with Mild Cognitive Impairment (MC) using the Alzheimer's disease neuroimaging initiative (ADNI)
Clinical TrialPrincipal Investigator · Awarded by University of Southern California · 2015 - 2020Metabolic Signatures Underlying Vascular Risk Factors for Alzheimer-type Dementias
ResearchCo Investigator · Awarded by National Institutes of Health · 2015 - 2020Metabolic Network Analysis of Biochemical Trajectories in Alzheimer's Disease
ResearchCo Investigator · Awarded by National Institutes of Health · 2017 - 2020A Biomarker-Based Trial of Plasmalogen Repletion in MCI/AD
ResearchCo Investigator · Awarded by University of Pennsylvania · 2019 - 2020Metabolic Networks and Pathways in Alzheimer's Disease
ResearchCo Investigator · Awarded by National Institutes of Health · 2014 - 2019An open label, multicenter study evaluating the imaging characteristics of follow up 18F-AV-1451 scan in subjects that participated in the confirmatory cohort of 18F-AV-1451-A05
Clinical TrialPrincipal Investigator · Awarded by Avid Radiopharmaceuticals Inc · 2016 - 2019Lifestyle, CVD Risk and Cognitive Impairment
ResearchCo Investigator · Awarded by National Institutes of Health · 2011 - 2018EVP-6124-026
Clinical TrialPrincipal Investigator · Awarded by FORUM Pharmaceuticals Inc. · 2014 - 2017EVP-6124-025
Clinical TrialPrincipal Investigator · Awarded by FORUM Pharmaceuticals Inc. · 2014 - 2017Baseline Bio-molecular Models to Predict Infectious Disease Susceptibility
ResearchClinical Investigator · Awarded by Defense Advanced Research Projects Agency · 2015 - 2016Pilot Combination Trial of Mild Cognitive Impairment with Depression Supplement
ResearchPrincipal Investigator · Awarded by Research Foundation for Mental Hygiene, Inc. · 2013 - 2016Pilot Combination Trial of Mild Cognitive Impairment with Depression
ResearchPrincipal Investigator · Awarded by Research Foundation for Mental Hygiene, Inc. · 2011 - 2015Cortical Beta-amyloid Levels and Neurocognitive Performance After Cardiac Surgery
ResearchCo Investigator · Awarded by National Institutes of Health · 2011 - 2014Vascular Depression: Longitudinal Changes
ResearchInvestigator · Awarded by National Institutes of Health · 2007 - 2011Metabolic Signatures for Alzheimer's Disease
ResearchCo Investigator · Awarded by National Institutes of Health · 2007 - 2011PREMIER Mental Health Interventions Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2002 - 2010fMRI Studies in Early Alzheimer's Disease
ResearchInvestigator · Awarded by National Institutes of Health · 2001 - 2008Exercise Training And Depression In Older Adults
ResearchCo Investigator · Awarded by National Institutes of Health · 1998 - 2007Treatment Outcomes of Vascular Depression
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2001 - 2007Development of the Inventory of Depressive Symptomatology
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2003 - 2006A Clinical Trial of Donepezil for Down Syndrome
ResearchCollaborator · Awarded by National Institutes of Health · 2001 - 2004A Placebo...Extract Hypericum Perforatum In Major Depressi
Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 1998 - 2001Alzheimers Disease-- Antemortem Markers
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1995 - 1998External Relationships
- AHEL Ltd
- Alzheon
- Cornell University
- Evidation Health
- Hakcnesack Medical Center
- Keel Digital
- Live Love Laugh - non-profit organization devoted to improving mental health.
- Lumos Labs
- Lundbeck
- MarvelBiome
- Prospiral
- Transposon Therapeutics
- UMethod
This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.