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Fan Yuan

Professor of Biomedical Engineering
Biomedical Engineering
Duke Box 90281, Durham, NC 27708-0281
Rm 1385, Fciemas, Duke Univers, Durham, NC 27708-0281

Research Interests


Principles and mechanisms of delivery for drugs, genes, and vaccines; pharmacokinetics; electrotransfer or electroporation technology; and tumor pathophysiology.

Selected Grants


Chemically Assisted Electrotransfer of DNA

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2027

University Training Program in Biomolecular and Tissue Engineering

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1994 - 2027

Computational Design of Antibody-Drug-Excipient Nanoparticles

ResearchCollaborator · Awarded by National Institutes of Health · 2023 - 2026

CIVICS Component A - Option 5

ResearchInvestigator · Awarded by National Institutes of Health · 2019 - 2025

Leica Stellaris Confocal for a Campus-wide Shared Resource

EquipmentMajor User · Awarded by National Institutes of Health · 2024 - 2025

Non-Canonical Pathways for Electrogene Transfer

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2023

CIVICS A - Option 23B

ResearchPrincipal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2020 - 2022

Pharmacological Sciences Training Program

Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by National Institutes of Health · 1975 - 2020

Investigation of Endocytosis Involved in Electrotransfection

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2013 - 2018

OCT measurement of TM/SC stiffness in living mice

ResearchCollaborator · Awarded by BrightFocus Foundation · 2015 - 2017

Analysis of DNA transport in electrotransfected cells

ResearchPrincipal Investigator · Awarded by National Science Foundation · 2013 - 2017

Shear stress regulation of barrier function in Schlemm's canal

FellowshipCo-Sponsor · Awarded by National Institutes of Health · 2014 - 2016

Biosensor Biocompatibility

ResearchInvestigator · Awarded by National Institutes of Health · 1999 - 2015

Delivery of Bacterial Therapeutics to Solid Tumors

ResearchPrincipal Investigator · Awarded by National Science Foundation · 2009 - 2013

Intravital point-scanning confocal microscope

ResearchMajor User · Awarded by National Institutes of Health · 2010 - 2011

Electric Field-Mediated Gene Delivery in MCL Tumor Model

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2006 - 2010

Training in Biomolecular and Tissue Engineering

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2003 - 2009

Electric Field-Forced Gene Transfer in Solid Tumors

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2002 - 2009

Electric Field-Forced Gene Transfer in Solid Tumors

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2002 - 2007

CAREER: Improving Convective Transport of Drugs and Genes in Solid Tumors

ResearchPrincipal Investigator · Awarded by National Science Foundation · 2000 - 2006

Upgrade of a Shared Instrumentation Resource in the PSOE: The Laser Scanning Confocal Microscope

EquipmentCo-Principal Investigator · Awarded by Lord Foundation of North Carolina · 2002 - 2005

External Relationships


  • SalioGen Therapeutics, Inc.

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.