Overview
Dr. Devi’s research interests include functional genomics, anti-cancer drug discovery and development, mechanisms of cancer cell signaling, tumor immunity and applications thereof for overcoming therapeutic resistance in cancer.
The lab has established prostate, inflammatory breast cancer and ovarian cellular and tumor models.
The lab has established prostate, inflammatory breast cancer and ovarian cellular and tumor models.
Current Appointments & Affiliations
Professor in Surgery
·
2023 - Present
Surgery, Surgical Sciences,
Surgery
Professor in Pathology
·
2023 - Present
Pathology,
Clinical Science Departments
Member of the Duke Cancer Institute
·
2005 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Tumor Microenvironment Modulation by Tumor-Associated Macrophages: Implications for Neoadjuvant Chemotherapy Response in Breast Cancer.
Journal Article Breast Cancer (Dove Med Press) · 2025 BACKGROUND: Tumor-associated macrophages (TAMs) constitute an important part of the tumor microenvironment of breast cancer (BC), and they play an essential role in modulating tumor growth and invasion. However, the role of TAMs in neoadjuvant chemotherapy ... Full text Link to item CiteAltered ribosomal profile in acquired resistance and reversal associates with pathological response to chemotherapy in inflammatory breast cancer.
Journal Article NPJ Breast Cancer · July 29, 2024 Therapeutic resistance presents a significant hurdle in combating inflammatory breast cancer (IBC), adding to the complexity of its management. To investigate these mechanisms, we conducted a comprehensive analysis using transcriptomic and proteomic profil ... Full text Link to item CiteXIAP overexpressing inflammatory breast cancer patients have high infiltration of immunosuppressive subsets and increased TNFR1 signaling targetable with Birinapant.
Journal Article Transl Oncol · May 2024 OBJECTIVE: To assess the expression pattern of X-linked inhibitor of apoptosis protein (XIAP), a cellular stress sensor, and delineate the associated changes in the tumor immune microenvironment (TiME) for prognostic value and new therapeutic targets in in ... Full text Link to item CiteRecent Grants
Duke University Program in Environmental Health
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2019 - 2029Medical Scientist Training Program
Inst. Training Prgm or CMEPreceptor · Awarded by National Institute of General Medical Sciences · 2022 - 2027Molecular Determinants of Health Disparities in Inflammatory Breast Cancer
ResearchPrincipal Investigator · Awarded by National Cancer Institute · 2021 - 2026View All Grants
Education, Training & Certifications
University of Nebraska, College of Medicine ·
1998
Ph.D.