Gayathri R. Devi

Dr. Devi’s research interests include functional genomics, anti-cancer drug discovery and development, mechanisms of cancer cell signaling, tumor immunity and applications thereof for overcoming therapeutic resistance in cancer.

The lab has established prostate, inflammatory breast cancer and ovarian cellular and tumor models.

Current Appointments & Affiliations

Adjunct Professor in the Department of Surgery · 2026 - Present Surgery, Surgical Sciences, Surgery

In the News

Published November 22, 2023

Urban Environmental Factors Driving Breast Cancer Incidence

Published January 9, 2019

Cancer Cells Steer a Jagged Path

Published March 28, 2017

Study Shows How BPA May Affect Inflammatory Breast Cancer

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Recent Publications

Multiscale Modeling Uncovers Macrophage Infiltration and TNF-α Signaling Networks for Targeting in Inflammatory Breast Cancer Tumor Emboli.

Journal Article bioRxiv · August 12, 2025 Inflammatory breast cancer (IBC) tumors are characterized by diffuse clusters of cells found in dermal tissue and lymphatic vessels, known as tumor emboli. Thus, IBC needs a novel treatment because it is the most aggressive breast cancer subtype. We hypoth ... Full text Link to item Cite

Tumor Microenvironment Modulation by Tumor-Associated Macrophages: Implications for Neoadjuvant Chemotherapy Response in Breast Cancer.

Journal Article Breast Cancer (Dove Med Press) · 2025 BACKGROUND: Tumor-associated macrophages (TAMs) constitute an important part of the tumor microenvironment of breast cancer (BC), and they play an essential role in modulating tumor growth and invasion. However, the role of TAMs in neoadjuvant chemotherapy ... Full text Link to item Cite

Altered ribosomal profile in acquired resistance and reversal associates with pathological response to chemotherapy in inflammatory breast cancer.

Journal Article NPJ Breast Cancer · July 29, 2024 Therapeutic resistance presents a significant hurdle in combating inflammatory breast cancer (IBC), adding to the complexity of its management. To investigate these mechanisms, we conducted a comprehensive analysis using transcriptomic and proteomic profil ... Full text Link to item Cite

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Education, Training & Certifications

University of Nebraska, College of Medicine · 1998 Ph.D.