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Goldis Malek

Professor of Ophthalmology
Ophthalmology, Vitreoretinal Diseases & Surgery
Box 3802 Med Ctr, DUMC, Durham, NC 27710
Albert Eye Research Institute, Room 4006, Durham, NC 27710

Selected Grants


Deciphering the role of osteopontin in the aging eye and age-related macular degeneration

ResearchPrincipal Investigator · Awarded by National Eye Institute · 2023 - 2027

Cell and Molecular Biology Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2021 - 2026

Nuclear receptor driven mechanisms in aging and AMD

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2021 - 2025

Regulation of inflammation and lipid homeostasis by the aryl hydrocarbon receptor in age-related macular degeneration

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2023

Novel signaling pathways regulated by the liver x receptor in age-related macular degeneration

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2022

Deciphering the role of osteopontin in the aging eye and age-related macular degeneration

ResearchPrincipal Investigator · Awarded by National Eye Institute · 2023 - 2027

Cell and Molecular Biology Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2021 - 2026

Nuclear receptor driven mechanisms in aging and AMD

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2021 - 2025

Regulation of inflammation and lipid homeostasis by the aryl hydrocarbon receptor in age-related macular degeneration

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2023

Novel signaling pathways regulated by the liver x receptor in age-related macular degeneration

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2022

Testing Gene Therapy in Models of Geographic Atrophy

ResearchPrincipal Investigator · Awarded by University of Florida · 2016 - 2022

Organization and Function of Cellular Structure

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1975 - 2020

LXR as a novel therapeutic target in diabetic retinopathy

ResearchPrincipal Investigator · Awarded by University of Alabama at Birmingham · 2017 - 2019

Investigating the role of a novel nuclear receptor in aging and AMD.

ResearchPrincipal Investigator · Awarded by Carl Marshall Reeves & Mildred Almen Reeves Foundation, Inc. · 2017 - 2018

The role of a macrophage chemotactic factor in AMD

ResearchPrincipal Investigator · Awarded by BrightFocus Foundation · 2015 - 2017

Targeting the signaling pathway of a lipid activated nuclear receptor for the treatment of dry age-related macular degeneration.

ResearchPrincipal Investigator · Awarded by Edward N. & Della L. Thome Memorial Foundation · 2014 - 2017

LXR as a novel therapeutic target in diabetic retinopathy

ResearchPrincipal Investigator · Awarded by The Trustees of Indiana University · 2015 - 2017

Lipid Activated Nuclear Receptors in Age-Related Macular Degeneration

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2011 - 2017

Immune Responses in Macular Degeneration

ResearchInvestigator · Awarded by National Institutes of Health · 2005 - 2011

External Relationships


  • Allianthera Biopharma (ATB)
  • Current Eye Research Journal / Taylor and Francis
  • Osanni Bio, Inc

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.