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Gregory E. Crawford
Wilburt C. Davison Distinguished Professor of Pediatrics
Pediatrics, Medical Genetics
greg.crawford@duke.edu
Box 3382 Med Ctr, Durham, NC 27710
Room 2111 CIEMAS, Durham, NC 27708
Research
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Selected Grants
Leveraging novel mouse models to investigate toxic metal exposures on brain aging and Alzheimer's disease
Research
Principal Investigator ·
Awarded by Boston University ·
2024 - 2029
Epigenetic Programming of T Cells for Enhanced Cellular Immunotherapy
Research
Co Investigator ·
Awarded by National Cancer Institute ·
2024 - 2029
To support research on the development of CRISPR-based epigenome editing tools to refine genome wide association studies
Research
Co Investigator ·
Awarded by Open Philanthropy Project ·
2018 - 2027
ATRXmutations,innate immune activation and therapeutic vunerabilityin malignant gliomas
Research
Investigator ·
Awarded by National Cancer Institute ·
2022 - 2027
Understanding gene regulation in schizophrenia-associated loci using high-throughput epigenetic CRISPR screens
Fellowship
Principal Investigator ·
Awarded by National Institute of Mental Health ·
2024 - 2027
Medical Scientist Training Program
Inst. Training Prgm or CME
Preceptor ·
Awarded by National Institute of General Medical Sciences ·
2022 - 2027
Beyond GWAS: High Throughput Functional Genomics & Epigenome Editing to Elucidate the Effects of Genetic Associations for Schizophrenia
Research
Principal Investigator ·
Awarded by National Institute of Mental Health ·
2021 - 2027
Myovascular Mechanisms of Cardiac Growth and Regeneration
Research
Collaborator ·
Awarded by National Heart, Lung, and Blood Institute ·
2022 - 2026
Untangling the diversity in the genetic architecture of late-onset Alzheimer's disease using single cell multi-omics
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2022 - 2026
High-Throughput Functional Annotation of Gene Regulatory Elements and Variants Critical to Complex Cellular Phenotypes
Research
Co-Principal Investigator ·
Awarded by National Human Genome Research Institute ·
2021 - 2026
Discovery and validation of genetic variation impacting the gene regulatory landscape during human cortical development
Research
Principal Investigator ·
Awarded by University of North Carolina - Chapel Hill ·
2021 - 2026
Duke Center for Advancement of Child Health (CAtCH).
Inst. Training Prgm or CME
Mentor ·
Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development ·
2021 - 2026
Genetic and Genomics Training Grant
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
2020 - 2025
Lewy body neuropathologies and SNCA gene: variants expression and splicing
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2020 - 2025
Genomics, variation, and evolution of cerebellar circuits linked to higher cognitive functions in humans
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2021 - 2025
The Duke FUNCTION Center: Pioneering the comprehensive identification of combinatorial noncoding causes of disease
Research
Co-Principal Investigator ·
Awarded by National Human Genome Research Institute ·
2020 - 2025
Summer Scholars in Genome Sciences & Medicine
Inst. Training Prgm or CME
Significant Contributor ·
Awarded by National Institutes of Health ·
2017 - 2025
Epigenomic Reprogramming in Patient Derived Models of Colorectal Cancer
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2018 - 2024
Quantifying the genetic diversity of human regulatory element activity
Research
Co-Principal Investigator ·
Awarded by National Institutes of Health ·
2019 - 2024
Mapping Epigenetic Memory of Exposure New To Observe (MEMENTO)
Research
Co Investigator ·
Awarded by Defense Advanced Research Projects Agency ·
2019 - 2024
Chromatin regulation during brain development and in ASD
Research
Principal Investigator ·
Awarded by Yale University ·
2019 - 2023
Postdoctoral Training in Genomic Medicine Research
Inst. Training Prgm or CME
Co-Mentor ·
Awarded by National Institutes of Health ·
2017 - 2023
IRES Track 1 IRTG Engaged in Dissecting and Reengineering the Regulatory Genome
Research
Mentor ·
Awarded by National Science Foundation ·
2019 - 2023
Chromatin Mechanisms of Neuronal Maturation
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2017 - 2023
Thwarting Influenza with RNA-powered Modulators (ThIRM)
Research
Co Investigator ·
Awarded by Georgia Institute of Technology ·
2019 - 2023
Regulatory Mechanisms of CD4+ T Cell Differentiation
Research
Co-Principal Investigator ·
Awarded by National Institutes of Health ·
2017 - 2022
Identifying Pathogenic Non-Coding Mutations in Rare Mendelian Disease
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2019 - 2022
Genetic epidemiology of rare and regulatory variants for metabolic traits
Research
Principal Investigator ·
Awarded by University of North Carolina - Chapel Hill ·
2017 - 2022
Systems Toxicogenomics of Endocrine Disrupting Chemicals in Brain
Research
Principal Investigator ·
Awarded by North Carolina State University ·
2016 - 2022
Effects of perfluorobutane sulfonate (PFBS) exposure on adverse pregnancy outcomes and fetal development
Research
Collaborator ·
Awarded by National Institutes of Health ·
2017 - 2022
Bioinformatics and Computational Biology Training Program
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
2005 - 2021
Epigenome Editing Technologies to Control Diverse Biological Functions
Research
Co Investigator ·
Awarded by Allen Institute for Brain Science ·
2017 - 2021
3/3 Chromatin regulation during brain development and in ASD
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2018 - 2021
HARDAC-M: Enabling memory-intensive computation for genomics
Equipment
Major User ·
Awarded by North Carolina Biotechnology Center ·
2020 - 2021
Exploring the Role of Dynamic Chromatin Occupancy in Transcriptional Regulation - Non-competing renewal III
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2016 - 2021
Identification and application of regulatory elements for heart regeneration
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2016 - 2020
New methods for quantitative modeling of protein-DNA interactions
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2015 - 2020
Genetics Training Grant
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
1979 - 2020
Organization and Function of Cellular Structure
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
1975 - 2020
Cellular and Molecular Systems Biology of Preterm Birth
Research
Principal Investigator ·
Awarded by University of Chicago ·
2015 - 2019
Decoding schizophrenia-From GWAS to functional regulatory variants
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2014 - 2019
Decoding and Reprogramming the Corticosteroid Transcriptional Regulatory Network
Research
Investigator ·
Awarded by National Institutes of Health ·
2015 - 2018
Engineering Targeted Epigenetic Modifiers for Precise Control of Gene Regulation
Research
Co-Principal Investigator ·
Awarded by National Institutes of Health ·
2013 - 2018
Genes, genomes, and genotoxicity: in vivo epigenetic toxicology of 1,3-butadiene
Research
Principal Investigator ·
Awarded by University of North Carolina - Chapel Hill ·
2013 - 2018
GWAS TO GENE FUNCTION: NOS1AP AND OTHER QT INTERVAL GENES
Research
Principal Investigator ·
Awarded by Johns Hopkins University ·
2014 - 2017
The function and regulation of the novel pregnancy-specific hexokinase HKDC1
Research
Co Investigator ·
Awarded by Northwestern University ·
2015 - 2016
Genome-Wide Mapping of Enhancer Elements for Neuronal Differentiation Genes
Research
Co-Principal Investigator ·
Awarded by National Institutes of Health ·
2013 - 2016
Microbial Regulation of Nuclear Receptor Activity in the Intestinal Epithelium
Research
Co-Principal Investigator ·
Awarded by Baylor College of Medicine ·
2014 - 2016
Comprehensive Identification of Active Functional Elements in Human Chromatin
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2007 - 2013
Identification of Disease-Causing Mutations in SCID Using Exome-Wide Sequencing
Research
Investigator ·
Awarded by National Institutes of Health ·
2009 - 2012
High-performance Computing System for Bioinformatics
Equipment
Major User ·
Awarded by National Institutes of Health ·
2009 - 2010
Generation of a genome-wide DNAse hypersensitive library
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2006 - 2010
