Scholars@Duke
Harry Chiang

Harry Chiang

House Staff
Surgery
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Selected Publications

Comparing Patient-Reported Outcomes with Computational Fluid Dynamics-Derived Nasal Airflow After Nasal Airway Surgery: Prioritizing the Patient's Perception of Nasal Obstruction.

Journal Article Facial Plast Surg Aesthet Med · August 14, 2024 Background: Some patients report persistent nasal obstruction after surgical treatment despite objective improvement. Objective: To compare patients' perceptions of nasal obstruction after surgery with objective nasal airflow as determined by computational ... Full text Open Access Link to item Cite

Nasal airway obstruction in patients with cleft lip nasal deformity: A systematic review.

Journal Article J Plast Reconstr Aesthet Surg · May 2024 BACKGROUND: Cleft lip nasal deformity (CLND)-associated nasal airway obstruction (CL-NAO) may be inadequately characterized, with its functional implications subsequently underappreciated and neglected. The purpose of this systematic review is to (1) summa ... Full text Open Access Link to item Cite

Challenges in the Management of Symptomatic Fallopian Canal Meningoceles: A Multicenter Case Series and Literature Review.

Journal Article Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · April 2024 ObjectiveTo describe the presentations, the diagnosis, our treatment approaches, and the outcomes for 11 patients with fallopian canal meningocele (FCM).Study design multicenterRetrospective case series.SettingTertiary referral c ... Full text Open Access Cite

Olfactory drug delivery with intranasal sprays after nasal midvault reconstruction.

Journal Article Int J Pharm · September 25, 2023 Conductive olfaction and nose to brain drug delivery are important processes that remain limited by inadequate odorant or drug delivery to the olfactory airspace. Primary challenges include anatomic barriers and poor targeting to the olfactory region. This ... Full text Open Access Link to item Cite

The evolution of facial reanimation techniques.

Journal Article Am J Otolaryngol · 2023 This review article provides an updated discussion on evidence-based practices related to the evaluation and management of facial paralysis. Ultimately, the goals of facial reanimation include obtaining facial symmetry at rest, providing corneal protection ... Full text Open Access Link to item Cite

Characterizing Olfactory Dysfunction in Patients with Unilateral Cleft Lip Nasal Deformities.

Journal Article Facial Plast Surg Aesthet Med · 2023 Background: Unilateral cleft lip nasal deformity (uCLND) is associated with olfactory dysfunction, but the underlying etiology remains poorly understood. Objective: To investigate the etiology of uCLND-associated olfactory dysfunction using clinical, compu ... Full text Open Access Link to item Cite

Systematic Review of Otologic and Neurotologic Surgery Using the 3-dimensional Exoscope.

Journal Article Otology & neurotology open · December 2022 ObjectiveThe 3D exoscope is an emerging technology that has been met with success in neurosurgery and is now increasingly used in otologic and neurotologic surgery. There is currently no consensus on its safety, efficiency, and utility, compared t ... Full text Open Access Cite

3D-Printed Microneedles Create Precise Perforations in Human Round Window Membrane in Situ.

Journal Article Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · February 2020 HypothesisThree-dimensional (3D)-printed microneedles can create precise holes on the scale of micrometers in the human round window membrane (HRWM).BackgroundAn intact round window membrane is a barrier to delivery of therapeutic and dia ... Full text Open Access Cite

Anatomical and Functional Consequences of Microneedle Perforation of Round Window Membrane.

Journal Article Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · February 2020 HypothesisMicroneedles can create microperforations in the round window membrane (RWM) without causing anatomic or physiologic damage.BackgroundReliable delivery of agents into the inner ear for therapeutic and diagnostic purposes remains ... Full text Open Access Cite

Inner ear delivery: Challenges and opportunities.

Journal Article Laryngoscope investigative otolaryngology · February 2020 ObjectivesThe treatment of inner ear disorders remains challenging due to anatomic barriers intrinsic to the bony labyrinth. The purpose of this review is to highlight recent advances and strategies for overcoming these barriers and to discuss pro ... Full text Open Access Cite

Small molecule delivery across a perforated artificial membrane by thermoreversible hydrogel poloxamer 407.

Journal Article Colloids and surfaces. B, Biointerfaces · October 2019 Microperforations in the round window membrane have been suggested for enhancing the rate and reliability of drug delivery into the cochlea. Intratympanic injection, the most common delivery method, involves injecting therapy into the middle ear to establi ... Full text Open Access Cite

Spatial fluctuations of fluid velocities in flow through a three-dimensional porous medium.

Journal Article Physical review letters · August 2013 We use confocal microscopy to directly visualize the spatial fluctuations in fluid flow through a three-dimensional porous medium. We find that the velocity magnitudes and the velocity components both along and transverse to the imposed flow direction are ... Full text Open Access Cite