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Huanghe Yang

Associate Professor of Biochemistry
Biochemistry
Box 3711,DUMC, Durham, NC 27710
213 Nanaline H Duke, Box 3711, DUMC, Durham, NC 27710

Current Duke Appointments & Affiliations


Associate Professor of Biochemistry · 2023 - Present Biochemistry, Basic Science Departments
Assistant Professor of Cell Biology · 2022 - Present Cell Biology, Basic Science Departments
Associate Professor in Medicine · 2024 - Present Medicine, Hematology, Medicine
Associate Professor in Neurobiology · 2024 - Present Neurobiology, Basic Science Departments
Associate Professor of Biomedical Engineering · 2025 - Present Biomedical Engineering, Pratt School of Engineering
Associate Professor in Obstetrics and Gynecology · 2026 - Present Obstetrics and Gynecology, Reproductive Sciences, Obstetrics and Gynecology
Faculty Network Member of the Duke Institute for Brain Sciences · 2019 - Present Duke Institute for Brain Sciences, University Institutes and Centers

Recent News Items


Published October 5, 2017
Two Duke Faculty Win NIH New Innovator Awards

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Recent Scholarly Works


Gardos potassium channel amplifies PIEZO1-TMEM16F coupling in red blood cells

Preprint · May 29, 2026 ABSTRACT In red blood cells (RBCs), the mechanosensitive channel PIEZO1 provides an upstream Ca 2+ signal that activates TMEM16F, a ... Full text Cite

Targeting PIEZO1-TMEM16F Coupling to Mitigate Sickle Cell Disease Complications.

Journal article Am J Hematol · December 2025 A deeper understanding of sickle cell disease (SCD) pathophysiology is critical for identifying novel therapeutic targets. A hallmark of SCD is abnormal phosphatidylserine (PS) exposure on sickle red blood cells (RBCs), which contributes to anemia, thrombo ... Full text Open Access Link to item Cite
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Recent Grants


Cell and Molecular Biology Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institute of General Medical Sciences · 2026 - 2031

Hematology & Transfusion Medicine

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 1975 - 2031

LpxH Inhibitors as Novel Therapeutics Against Multidrug-resistant Enterobacterales

ResearchCo Investigator · Awarded by National Institutes of Health · 2025 - 2030

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Education


Washington University in St. Louis · 2008 Ph.D.

External Links


Lab Link