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Huanghe Yang
Associate Professor of Biochemistry
Biochemistry
huanghe.yang@duke.edu
https://orcid.org/0000-0001-9521-9328
Box 3711,DUMC, Durham, NC 27710
213 Nanaline H Duke, Box 3711, DUMC, Durham, NC 27710
Research
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Selected Grants
Cell and Molecular Biology Training Program
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institute of General Medical Sciences ·
2026 - 2031
LpxH Inhibitors as Novel Therapeutics Against Multidrug-resistant Enterobacterales
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2025 - 2030
A molecular dissection of BK channelopathy in neurological disorders
Research
Principal Investigator ·
Awarded by Washington University in St. Louis ·
2025 - 2030
Neurobiology Training Program
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institute of Neurological Disorders and Stroke ·
2024 - 2029
Advancing mechanistic understanding of membrane ion and lipid transport
Research
Principal Investigator ·
Awarded by National Institute of General Medical Sciences ·
2024 - 2029
Complement and thrombosis in HIT
Research
Co Investigator ·
Awarded by National Heart, Lung, and Blood Institute ·
2025 - 2028
Deciphering mechanobiology in human diseases by developing a TMEM63B channelopathy mouse model
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2024 - 2027
Identification and validation of LPA/LPAR signaling in temporomandibular disorder pain
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2024 - 2027
Hematology & Transfusion Medicine (T32)
Inst. Training Prgm or CME
Preceptor ·
Awarded by National Heart, Lung, and Blood Institute ·
1975 - 2027
Investigating BK channel regulatory subunit LRRC55 in pain
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2024 - 2026
Cell and Molecular Biology Training Program
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institute of General Medical Sciences ·
2021 - 2026
BBOX1 is a Novel Oncogenic Driver in Triple Negative Breast Cancer
Research
Principal Investigator ·
Awarded by University of Texas Southwestern Medical Center ·
2021 - 2026
Elucidating the Molecular Mechanism of Excessive Phosphatidylserine Exposure in Sickle Red Cells
Fellowship
Principal Investigator ·
Awarded by American Society of Hematology ·
2024 - 2025
Role of TMEM16F in Hereditary Xerocytosis Manifestations
Fellowship
Principal Investigator ·
Awarded by American Society of Hematology ·
2023 - 2025
Optogenetic stimulation of TMEM16F to control phospholipid flip-flop
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2022 - 2024
Molecular Underpinning and Functions of Endothelial Shear-induced Chloride Conductance
Fellowship
Principal Investigator ·
Awarded by American Heart Association ·
2022 - 2023
Manipulating TMEM16F lipid scramblase to understand transbilayer phospholipid transport phenomenon
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2017 - 2022
Targeting BK calcium-activated potassium channels in absence epilepsy
Fellowship
Principal Investigator ·
Awarded by American Epilepsy Society ·
2020 - 2021
Investigate the expression and activation mechanism of TMEM16F phospholipid scramblase in endothelial cells.
Fellowship
Principal Investigator ·
Awarded by American Heart Association ·
2020 - 2020
Investigate the Molecular Mechanism of TMEM16A Ca2+-activated Chloride Channel Desensitization
Fellowship
Principal Investigator ·
Awarded by American Heart Association ·
2019 - 2020
Organization and Function of Cellular Structure
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
1975 - 2020
BW Collaborative Research Travel Grant: Collaborative effort to dissect the pathological roles of the newly discovered TMEM16 proteins in stroke
Research
Principal Investigator ·
Awarded by Burroughs Wellcome Fund ·
2017 - 2018
Elucidating the role of the calcium-activated chloride channels in essential tremor
Research
Principal Investigator ·
Awarded by International Essential Tremor Foundation ·
2017 - 2018
Ca2+ activated TMEM16 channels and their physiological roles in the brain
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2015 - 2018
https://orcid.org/0000-0001-9521-9328