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Jane Sanders Bellet

Professor of Dermatology
Dermatology
5324 McFarland Drive, Suite 410, Durham, NC 27707
5324 McFarland Drive, Suite 410, Durham, NC 27707

Selected Publications


Adult and Pediatric Nail Unit Melanoma: Epidemiology, Diagnosis, and Treatment.

Journal Article Cells · March 22, 2023 Nail unit melanoma (NUM) is an uncommon form of melanoma and is often diagnosed at later stages. Approximately two-thirds of NUMs are present clinically as longitudinal melanonychia, but longitudinal melanonychia has a broad differential diagnosis. Clinica ... Full text Link to item Cite

Quality and Perceived Usefulness of Patient-Submitted Store-and-Forward Teledermatology Images.

Journal Article JAMA Dermatol · October 1, 2022 IMPORTANCE: Patient-submitted images vary considerably in quality and usefulness. Studies that characterize patient-submitted images in a real-life setting are lacking. OBJECTIVE: To evaluate the quality and perceived usefulness of patient-submitted images ... Full text Link to item Cite

Blistering Lesions in a Newborn.

Journal Article Cutis · April 2022 Full text Link to item Cite

Nail discoloration in pediatric skin of color patients.

Journal Article Pediatr Dermatol · November 2021 Nail pigmentation in children can cause significant anxiety in parents and clinicians. Different pigments of the nails, such as yellow, orange, and green, can all occur; however, this paper will focus on the dark pigments: brown, gray, and black pigmentati ... Full text Link to item Cite

Progressive hyperpigmented rash in a 10-year-old boy.

Journal Article Pediatr Dermatol · November 2021 Full text Link to item Cite

That's Not Molluscum! A literature review of 109 cases of subepidermal calcified nodules.

Journal Article Pediatr Dermatol · July 2021 Subepidermal calcified nodule (SCN) is a rare presentation of idiopathic calcinosis cutis. A literature review was conducted, with 109 cases reported in 268 articles. We report the demographic data, SCN clinical and histological characteristics, common dif ... Full text Link to item Cite

Pediatric Nail Disorders.

Journal Article Dermatol Clin · April 2021 Many pediatric nail findings are normal variants and are no cause for alarm. Others represent congenital abnormalities or genetic syndromes for which there is no cure. Still others are inflammatory or infectious entities that require treatment. Pediatric n ... Full text Link to item Cite

Periocular infantile hemangioma masquerading as dacryocele.

Journal Article J AAPOS · October 2020 A 2-month-old boy developed a protuberant, blue nodule inferomedial to the left medial canthus. It was unresponsive to oral and intramuscular antibiotics. After developing difficulty breathing, he was admitted, with the diagnosis of a dacryocele, and, afte ... Full text Link to item Cite

Late growth of infantile hemangiomas in children >3 years of age: A retrospective study.

Journal Article J Am Acad Dermatol · February 2019 BACKGROUND: The proliferative phase of infantile hemangiomas (IHs) is usually complete by 9 months of life. Late growth beyond age 3 years is rarely reported. OBJECTIVE: To describe the demographic and clinic characteristics of a cohort of patients with la ... Full text Link to item Cite

Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases.

Journal Article Genet Med · April 2018 PurposeTo describe examples of missed pathogenic variants on whole-exome sequencing (WES) and the importance of deep phenotyping for further diagnostic testing.MethodsGuided by phenotypic information, three children with negative WES underwent targeted sin ... Full text Open Access Link to item Cite

Yellow-Orange Penile Papules.

Journal Article Pediatr Dermatol · September 2017 Full text Link to item Cite

Rapidly Growing Congenital Groin Mass.

Journal Article Pediatr Dermatol · May 2017 Full text Link to item Cite

De Novo Truncating Variants in ASXL2 Are Associated with a Unique and Recognizable Clinical Phenotype.

Journal Article Am J Hum Genet · October 6, 2016 The ASXL genes (ASXL1, ASXL2, and ASXL3) participate in body patterning during embryogenesis and encode proteins involved in epigenetic regulation and assembly of transcription factors to specific genomic loci. Germline de novo truncating variants in ASXL1 ... Full text Link to item Cite

Subungual leiomyoma in the left thumb of a 16-year-old female.

Journal Article J Cutan Pathol · April 2016 Cutaneous leiomyomata, which are benign smooth muscle neoplasms, commonly present as dermal-based nodules or papules with smooth borders and firm consistency. Digital, particularly subungual leiomyomata are quite rare. A 16-year-old female presented to nai ... Full text Link to item Cite

PERSISTENT LESION OF THE THUMBNAIL OF A 3-YEAR-OLD BOY

Journal Article PEDIATRIC DERMATOLOGY · January 1, 2016 Link to item Cite

Developmental anomalies of the skin.

Journal Article Semin Perinatol · February 2013 This paper focuses on the diagnosis and management of developmental anomalies of the skin that may be seen early in life. Common locations include the head, nose, preauricular area of the face, neck, and spine. Those that occur in or near the midline can b ... Full text Link to item Cite

Tinea capitis mimicking dissecting cellulitis.

Journal Article Pediatr Dermatol · 2013 Tinea capitis is a common disease of childhood that typically follows one of several clinical patterns. Our patient and several previously reported cases demonstrate the existence of a dissecting cellulitis-like presentation of tinea capitis. This variant ... Full text Link to item Cite

Adult and Pediatric Nail Unit Melanoma: Epidemiology, Diagnosis, and Treatment.

Journal Article Cells · March 22, 2023 Nail unit melanoma (NUM) is an uncommon form of melanoma and is often diagnosed at later stages. Approximately two-thirds of NUMs are present clinically as longitudinal melanonychia, but longitudinal melanonychia has a broad differential diagnosis. Clinica ... Full text Link to item Cite

Quality and Perceived Usefulness of Patient-Submitted Store-and-Forward Teledermatology Images.

Journal Article JAMA Dermatol · October 1, 2022 IMPORTANCE: Patient-submitted images vary considerably in quality and usefulness. Studies that characterize patient-submitted images in a real-life setting are lacking. OBJECTIVE: To evaluate the quality and perceived usefulness of patient-submitted images ... Full text Link to item Cite

Blistering Lesions in a Newborn.

Journal Article Cutis · April 2022 Full text Link to item Cite

Nail discoloration in pediatric skin of color patients.

Journal Article Pediatr Dermatol · November 2021 Nail pigmentation in children can cause significant anxiety in parents and clinicians. Different pigments of the nails, such as yellow, orange, and green, can all occur; however, this paper will focus on the dark pigments: brown, gray, and black pigmentati ... Full text Link to item Cite

Progressive hyperpigmented rash in a 10-year-old boy.

Journal Article Pediatr Dermatol · November 2021 Full text Link to item Cite

That's Not Molluscum! A literature review of 109 cases of subepidermal calcified nodules.

Journal Article Pediatr Dermatol · July 2021 Subepidermal calcified nodule (SCN) is a rare presentation of idiopathic calcinosis cutis. A literature review was conducted, with 109 cases reported in 268 articles. We report the demographic data, SCN clinical and histological characteristics, common dif ... Full text Link to item Cite

Pediatric Nail Disorders.

Journal Article Dermatol Clin · April 2021 Many pediatric nail findings are normal variants and are no cause for alarm. Others represent congenital abnormalities or genetic syndromes for which there is no cure. Still others are inflammatory or infectious entities that require treatment. Pediatric n ... Full text Link to item Cite

Periocular infantile hemangioma masquerading as dacryocele.

Journal Article J AAPOS · October 2020 A 2-month-old boy developed a protuberant, blue nodule inferomedial to the left medial canthus. It was unresponsive to oral and intramuscular antibiotics. After developing difficulty breathing, he was admitted, with the diagnosis of a dacryocele, and, afte ... Full text Link to item Cite

Late growth of infantile hemangiomas in children >3 years of age: A retrospective study.

Journal Article J Am Acad Dermatol · February 2019 BACKGROUND: The proliferative phase of infantile hemangiomas (IHs) is usually complete by 9 months of life. Late growth beyond age 3 years is rarely reported. OBJECTIVE: To describe the demographic and clinic characteristics of a cohort of patients with la ... Full text Link to item Cite

Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases.

Journal Article Genet Med · April 2018 PurposeTo describe examples of missed pathogenic variants on whole-exome sequencing (WES) and the importance of deep phenotyping for further diagnostic testing.MethodsGuided by phenotypic information, three children with negative WES underwent targeted sin ... Full text Open Access Link to item Cite

Yellow-Orange Penile Papules.

Journal Article Pediatr Dermatol · September 2017 Full text Link to item Cite

Rapidly Growing Congenital Groin Mass.

Journal Article Pediatr Dermatol · May 2017 Full text Link to item Cite

De Novo Truncating Variants in ASXL2 Are Associated with a Unique and Recognizable Clinical Phenotype.

Journal Article Am J Hum Genet · October 6, 2016 The ASXL genes (ASXL1, ASXL2, and ASXL3) participate in body patterning during embryogenesis and encode proteins involved in epigenetic regulation and assembly of transcription factors to specific genomic loci. Germline de novo truncating variants in ASXL1 ... Full text Link to item Cite

Subungual leiomyoma in the left thumb of a 16-year-old female.

Journal Article J Cutan Pathol · April 2016 Cutaneous leiomyomata, which are benign smooth muscle neoplasms, commonly present as dermal-based nodules or papules with smooth borders and firm consistency. Digital, particularly subungual leiomyomata are quite rare. A 16-year-old female presented to nai ... Full text Link to item Cite

PERSISTENT LESION OF THE THUMBNAIL OF A 3-YEAR-OLD BOY

Journal Article PEDIATRIC DERMATOLOGY · January 1, 2016 Link to item Cite

Developmental anomalies of the skin.

Journal Article Semin Perinatol · February 2013 This paper focuses on the diagnosis and management of developmental anomalies of the skin that may be seen early in life. Common locations include the head, nose, preauricular area of the face, neck, and spine. Those that occur in or near the midline can b ... Full text Link to item Cite

Tinea capitis mimicking dissecting cellulitis.

Journal Article Pediatr Dermatol · 2013 Tinea capitis is a common disease of childhood that typically follows one of several clinical patterns. Our patient and several previously reported cases demonstrate the existence of a dissecting cellulitis-like presentation of tinea capitis. This variant ... Full text Link to item Cite

Familial eruptive vellus hair cysts.

Journal Article Pediatr Dermatol · 2012 Featured Publication Eruptive vellus hairs cysts are benign papules consisting of small cysts containing multiple vellus hairs. An eruption commonly develops on the chest and sometimes the upper extremities. These papules are asymptomatic or rarely pruritic. Only a few cases o ... Full text Link to item Cite

Treatment of hypergranulation tissue with high potency topical corticosteroids in children.

Journal Article Pediatr Dermatol · 2012 Hypergranulation is having more granulation tissue than needed to fill a wound defect. Some pediatric dermatologists and most dermatologic surgeons will encounter this complication during their careers. Associated factors include wound site, prolonged infl ... Full text Link to item Cite

Clinical and dermoscopic features of 88 scalp naevi in 39 children.

Journal Article Br J Dermatol · July 2011 Featured Publication BACKGROUND: Paediatric scalp naevi may represent a source of anxiety for practitioners and parents, as the clinical and dermoscopic features of typical naevi have yet to be defined. Prompted by concern about the large size, irregular borders and colour var ... Full text Link to item Cite

Diagnosis and treatment of primary focal hyperhidrosis in children and adolescents.

Journal Article Semin Cutan Med Surg · June 2010 Featured Publication Primary focal hyperhidrosis is a disorder of excessive sweating that occurs in the axillae, palms, soles, and craniofacial region in amounts greater than needed for thermal regulation. Although the etiology is unknown, this disorder can cause significant e ... Full text Link to item Cite

Photographic survey of scalp nevi in children

Conference JOURNAL OF INVESTIGATIVE DERMATOLOGY · April 1, 2010 Link to item Cite

Intertriginous pustular psoriasis.

Journal Article J Am Acad Dermatol · April 2009 Featured Publication We describe 6 patients who presented during infancy with erythematous papules or pustules localized to the neck and sometimes other intertriginous areas as well. Most of these infants were initially thought to have dermatitis or a bacterial or candidal inf ... Full text Link to item Cite

Difficult-to-control bleeding.

Journal Article Pediatr Dermatol · 2009 Featured Publication A 12-year-old girl presented for excision of a nevus sebaceous of the scalp. The surgery was complicated by unexpected difficult-to-control bleeding in the operating room. Numerous attempts to obtain hemostasis were unsuccessful including the use of local ... Full text Link to item Cite

Keratosis follicularis spinulosa decalvans in a family.

Journal Article J Am Acad Dermatol · March 2008 Keratosis follicularis spinulosa decalvans (KFSD) is a rare condition characterized by diffuse keratosis pilaris with a scarring alopecia of the scalp and associated photophobia, facial erythema, and palmoplantar keratoderma. Although initially described a ... Full text Link to item Cite

Cell adhesion protein expression in melanocytic matricoma.

Journal Article J Cutan Pathol · June 2007 Melanocytic matricoma is a rare neoplasm thought to recapitulate the hair follicle in anagen. The tumor forms a nodule in the dermis containing basaloid, intermediate and shadow cells admixed with pigmented melanocytes dispersed as single dendritic cells. ... Full text Link to item Cite

Skin complications of Bacillus Calmette-Guérin immunization.

Journal Article Curr Opin Infect Dis · April 2005 PURPOSE OF REVIEW: Bacillus Calmette-Guerin (BCG) vaccination has been performed since 1921, and remains the best method of preventing severe infections caused by Mycobacterium tuberculosis. Tuberculosis, in its various forms, remains a public health probl ... Full text Link to item Cite

Vitiligo in children: A review of classification, hypotheses of pathogenesis and treatment

Journal Article Anais Brasileiros de Dermatologia · 2005 Vitiligo is a relatively common dermatologic finding and one that has been observed since ancient times. Depigmentation of the skin, with loss of melanocytes on histology characterizes this disorder. A range of clinical phenotypes lead to varying degrees o ... Cite

Vitiligo in children: A review of classification, hypotheses of pathogenesis and treatment

Journal Article Anais Brasileiros de Dermatologia · January 1, 2005 Vitiligo is a relatively common dermatologic finding and one that has been observed since ancient times. Depigmentation of the skin, with loss of melanocytes on histology characterizes this disorder. A range of clinical phenotypes lead to varying degrees o ... Full text Cite

A patient with extensive stem cell factor-induced hyperpigmentation.

Journal Article Cutis · February 2003 Stem cell factor (SCF) is a cytokine that stimulates development of erythroid precursors and, consequently, may have potential importance in the treatment of certain anemias. We report a case of a young woman with Diamond-Blackfan anemia who received SCF t ... Link to item Cite

Comparison of in vivo efficacy and mechanism of action of antimurine monoclonal antibodies directed against TCR alpha beta (H57-597) and CD3 (145-2C11).

Journal Article Transplantation · October 27, 1995 Monoclonal antibodies (mAbs) directed against the T cell receptor (TCR)-associated CD3 chains and against the TCR-alpha beta heterodimer can inhibit allograft rejection in humans and in experimental animals. Since the effects of stimulation through these c ... Link to item Cite