Scholars@Duke
Jodi Antonelli

Jodi Antonelli

Associate Professor of Urology
Urology
jodi.antonelli@duke.edu
Box 3443 Med Ctr, Durham, NC 27710
Dept of Surgery, Durham, NC 27710

Selected Publications

A Patient-Prioritized Research Agenda for Clinical Trials in Kidney Stone Disease.

Journal Article J Urol · September 20, 2024 PURPOSE: To ensure that research on kidney stones provides meaningful impact for the kidney stone community, patients and caregivers should be engaged as stakeholders in clinical trial design, starting at study inception. This project aimed to elicit, refi ... Full text Link to item Cite

Work absence and productivity loss of patients undergoing a trial of spontaneous passage for ureteral stones.

Journal Article Urolithiasis · August 6, 2024 Patients with ureteral stones are often managed with a spontaneous trial of passage. While cost effective, the current literature has not examined the effects of a trial of passage on patients' work productivity. In this study, we aim to characterize work ... Full text Link to item Cite

The Impact of Single-Use Cystoscopes on Clinical Time Workflow in an Outpatient Setting.

Journal Article Urology · June 2024 OBJECTIVE: To evaluate the change in overall clinical encounter time and clinical capacity after transitioning to single-use cystoscopes (Ambu A/S, Ballerup, Denmark) in an outpatient urology setting. METHODS: A single-institution prospective study in an o ... Full text Link to item Cite

Exploring optimal settings for safe and effective thulium fibre laser lithotripsy in a kidney model.

Journal Article BJU Int · February 2024 OBJECTIVES: To explore the optimal laser settings and treatment strategies for thulium fibre laser (TFL) lithotripsy, namely, those with the highest treatment efficiency, lowest thermal injury risk, and shortest procedure time. MATERIALS AND METHODS: An in ... Full text Open Access Link to item Cite

The Impact of Bilateral Stone Disease on Patients' Disease Progression and Health-Related Quality of Life.

Journal Article J Endourol · December 2023 Purpose: Patients with recurring kidney stone events can expect significant morbidity and functional impairment. Few studies have evaluated the effect of bilateral kidney stones on disease progression and quality of life. We wanted to determine the associa ... Full text Link to item Cite

In vitro investigation of stone ablation efficiency, char formation, spark generation, and damage mechanism produced by thulium fiber laser.

Journal Article Urolithiasis · November 2, 2023 To investigate stone ablation characteristics of thulium fiber laser (TFL), BegoStone phantoms were spot-treated in water at various fiber tip-to-stone standoff distances (SDs, 0.5 ~ 2 mm) over a broad range of pulse energy (Ep, 0.2 ~ 2 J), frequency (F, 5 ... Full text Open Access Link to item Cite

Patients' Experiences With the Removal of a Ureteral Stent: Insights From In-depth Interviews With Participants in the USDRN STENTS Qualitative Cohort Study.

Journal Article Urology · August 2023 OBJECTIVE: To describe the experiences of patients undergoing stent removal in the USDRN Study to Enhance Understanding of Stent-Associated Symptoms (STENTS), a prospective, observational cohort study of patients with short-term ureteral stent placement po ... Full text Link to item Cite

In Pursuit of the Optimal Dusting Settings with the Thulium Fiber Laser: An In Vitro Assessment.

Journal Article J Endourol · August 2023 Objective: Low energy and high frequency settings are used in stone dusting for holmium lasers. Such settings may not be optimal for thulium fiber laser (TFL). With the seemingly endless combination of settings, we aim to provide guidance to the practicing ... Full text Link to item Cite

The Patient Voice: Stent Experiences After Ureteroscopy-Insights from In-Depth Interviews with Participants in the USDRN STENTS Nested Qualitative Cohort Study.

Journal Article J Endourol · June 2023 Purpose: Ureteral stents are commonly used after ureteroscopy and cause significant discomfort, yet qualitative perspectives on patients' stent experiences remain unknown. We describe psychological, functional, and interpersonal effects of post-ureteroscop ... Full text Link to item Cite

Risk Factors for Increased Stent-associated Symptoms Following Ureteroscopy for Urinary Stones: Results From STENTS.

Journal Article J Urol · May 2023 PURPOSE: The STudy to Enhance uNderstanding of sTent-associated Symptoms sought to identify risk factors for pain and urinary symptoms, as well as how these symptoms interfere with daily activities after ureteroscopy for stone treatment. MATERIALS AND METH ... Full text Link to item Cite

Top Ten Tips Palliative Care Clinicians Should Know About Urological Care.

Journal Article J Palliat Med · February 2023 Patients receiving palliative care (PC) can present with or develop a host of urological needs or complications. These needs can include attention to sexual health, urinary incontinence, genitourinary bleeding, and urinary tract obstruction by benign, mali ... Full text Link to item Cite

Alkali Citrate Content of Common Over-the-Counter and Medical Food Supplements.

Journal Article J Endourol · January 2023 Objective: Potassium citrate effectively decreases kidney stone recurrence, but it is costly and associated with side effects. While several over-the-counter supplements and medical foods purport to provide sufficient citrate to prevent recurrent stones, c ... Full text Link to item Cite

Benchtop Evaluation of Miniature Percutaneous Nephrolithotomy Lithotrites.

Journal Article J Endourol · November 2022 Introduction: Percutaneous nephrolithotomy (PCNL) is the preferred treatment for kidney stones >2 cm. While PCNL has traditionally been performed using 24F to 30F access sheaths, there is a trend toward smaller sheaths and scopes to perform mini-PCNL (mPCN ... Full text Link to item Cite

The Duration of Stone Disease and the Impact of a Stone Event on Patients' Quality of Life.

Journal Article J Endourol · October 2022 Introduction: With a 5-year stone recurrence rate of 30% to 50%, kidney stone formers are subject to significant morbidity that negatively impacts their health-related quality of life (HRQOL). We sought to determine the impact of age at kidney stone onset, ... Full text Link to item Cite

Reply by Authors.

Journal Article J Urol · September 2022 Full text Link to item Cite

Efficacy of Intramuscular Ketorolac for Preventing Renal Colic Post Stent Removal: Randomized Controlled Trial.

Journal Article J Urol · September 2022 PURPOSE: The treatment of stones ureteroscopically is associated with postoperative pain, thought to be due largely to the use of ureteral stents. In some, stent removal precipitates renal colic that can last from minutes to hours. We sought to determine i ... Full text Link to item Cite

Editorial introductions

Journal Article Current Opinion in Urology · July 1, 2022 Full text Cite

Quality of life impact and recovery after ureteroscopy and stent insertion: insights from daily surveys in STENTS.

Journal Article BMC Urol · April 6, 2022 BACKGROUND: Our objective was to describe day-to-day evolution and variations in patient-reported stent-associated symptoms (SAS) in the STudy to Enhance uNderstanding of sTent-associated Symptoms (STENTS), a prospective multicenter observational cohort st ... Full text Link to item Cite

Impact of an Enhanced Recovery After Surgery Protocol on Unplanned Patient Encounters in the Early Postoperative Period After Ureteroscopy.

Journal Article J Endourol · March 2022 Introduction: Ureteroscopy (URS) is associated with substantial patient-perceived morbidity. To improve the patient experience, we developed an enhanced recovery after surgery (ERAS) protocol for URS. We sought to determine if an ERAS protocol could reduce ... Full text Link to item Cite

The impact of the number of lifetime stone events on quality of life: results from the North American Stone Quality of Life Consortium.

Journal Article Urolithiasis · August 2021 To evaluate the impact of chronic stone recurrence on an individual's quality of life using the validated Wisconsin Stone Quality of Life (WISQOL) questionnaire. We collected cross-sectional data on patients with kidney stones from 14 institutions in North ... Full text Link to item Cite

Estimating the health-related quality of life of kidney stone patients: initial results from the Wisconsin Stone Quality of Life Machine-Learning Algorithm (WISQOL-MLA).

Journal Article BJU Int · July 2021 OBJECTIVE: To build the Wisconsin Stone Quality of Life Machine-Learning Algorithm (WISQOL-MLA) to predict urolithiasis patients' health-related quality of life (HRQoL) based on demographic, symptomatic and clinical data collected for the validation of the ... Full text Link to item Cite

Study to Enhance Understanding of Stent-Associated Symptoms: Rationale and Study Design.

Journal Article J Endourol · June 2021 Background: Ureteral stents are commonly employed after ureteroscopy to treat urinary stone disease, but the devices impose a substantial burden of stent-associated symptoms (SAS), including pain and urinary side effects. The NIDDK (National Institute of D ... Full text Link to item Cite

Prevention of Urinary Stones With Hydration (PUSH): Design and Rationale of a Clinical Trial.

Journal Article Am J Kidney Dis · June 2021 RATIONALE & OBJECTIVE: Although maintaining high fluid intake is an effective low-risk intervention for the secondary prevention of urinary stone disease, many patients with stones do not increase their fluid intake. STUDY DESIGN: We describe the rationale ... Full text Open Access Link to item Cite

Simple Nephrectomy in a Tertiary Care Safety Net Hospital-Patient Characteristics, Causes, Cost, and Renal Function Implications.

Journal Article Urology · March 2021 OBJECTIVE: To evaluate factors associated with simple nephrectomy at a safety net hospital with a diverse patient population and large catchment area. Simple nephrectomy is an underreported surgery. Performance of simple nephrectomy may represent a failure ... Full text Link to item Cite

Clinical and radiographic outcomes following salvage intervention for ureteropelvic junction obstruction.

Journal Article Int Braz J Urol · 2021 PURPOSE: We aimed to assess failure rates of salvage interventions and changes in split kidney function (SKF) following failed primary repair of ureteropelvic junction obstruction (UPJO). MATERIALS AND METHODS: A retrospective review of adult patients at a ... Full text Link to item Cite

Impact of Implementing Contrast-Enhanced Ultrasound for Antegrade Nephrostogram After Percutaneous Nephrolithotomy.

Journal Article J Ultrasound Med · January 2021 OBJECTIVES: To report results from a quality improvement (QI) project evaluating diagnostic performance, hospital resource use, and patient response data for postoperative contrast-enhanced ultrasound (CEUS) antegrade nephrostogram after percutaneous nephr ... Full text Link to item Cite

Urolithiasis in the COVID Era: An Opportunity to Reassess Management Strategies.

Journal Article Eur Urol · December 2020 Delayed evaluation and/or treatment for urolithiasis during the COVID-19 pandemic provide a unique opportunity to organically reassess many well-established stone management strategies. Nonopioid analgesia for renal colic and spontaneous passage trials app ... Full text Link to item Cite

Metabolic Syndrome Negatively Impacts Stone-Specific Quality of Life.

Journal Article J Endourol · November 2020 Purpose: Metabolic syndrome (MetS) is a cluster of metabolic diseases that is linked to atherosclerotic cardiovascular disease. MetS has also been linked to increased nephrolithiasis. However, limited research has been conducted on MetS and its impact on s ... Full text Link to item Cite

Editorial Comment.

Journal Article J Urol · October 2020 Full text Link to item Cite

Initial Results from the M-STONE Group: A Multi-Center Collaboration to Study Treatment Outcomes in Nephrolithiasis Evaluation.

Journal Article J Endourol · September 2020 Introduction: Despite proven effectiveness of medications in preventing stone recurrence, compliance with pharmacotherapy (PT) is often poor because of cost, side effects, and impact on lifestyle. We sought to compare the risk of stone recurrence between p ... Full text Link to item Cite

What Predicts Recurrent Kidney Stone after Parathyroidectomy in Patients with Primary Hyperparathyroidism?

Conference J Am Coll Surg · July 2020 BACKGROUND: Some, but not all, patients with primary hyperparathyroidism (PHPT) and kidney stone disease (KSD) are cured of their nephrolithiasis after parathyroidectomy. The goal of this study was to identify risk factors for recurrent KSD despite success ... Full text Link to item Cite

The effect of travel distance on health-related quality of life for patients with nephrolithiasis

Journal Article Canadian Urological Association Journal · January 1, 2020 Introduction: Urolithiasis causes a significant impact on health-related quality of life (HRQOL). Patients with kidney stones have high levels of stress and anxiety. Symptom resolution often requires treatment. Travel distance is a barrier to care but litt ... Full text Cite

Medical Expulsive Therapy for Urinary Stones: Future Trends and Knowledge Gaps.

Journal Article Eur Urol · November 2019 CONTEXT: Medical expulsive therapy (MET) for ureteral stones has become a controversial area due to the contradictory results of high-quality trials and meta-analyses. OBJECTIVE: We aimed to review the literature to evaluate the value of and future directi ... Full text Link to item Cite

Association of Patient Age and Gender with Kidney Stone Related Quality of Life.

Journal Article J Urol · August 2019 PURPOSE: Kidney stone formers have lower health related quality of life than nonstone formers. The North American Stone Quality of Life Consortium is a multicenter, longitudinal, prospective study of health related quality of life in patients with kidney s ... Full text Link to item Cite

Low Income and Nonwhite Race are Strongly Associated with Worse Quality of Life in Patients with Nephrolithiasis.

Journal Article J Urol · July 2019 PURPOSE: Kidney stones are a source of significant morbidity which have been shown to negatively impact health related quality of life. We sought to understand the association between health related quality of life, socioeconomic status and race among pati ... Full text Link to item Cite

The Effect of Thiazide and Potassium Citrate Use on the Health Related Quality of Life of Patients with Urolithiasis.

Journal Article J Urol · December 2018 PURPOSE: To our knowledge it is unknown whether the benefits of medical management of urolithiasis outweigh the potential side effects of the medications used, including potassium citrate and thiazide diuretics. Therefore, we evaluated the relationship bet ... Full text Link to item Cite

Dual-layer spectral detector CT: non-inferiority assessment compared to dual-source dual-energy CT in discriminating uric acid from non-uric acid renal stones ex vivo.

Journal Article Abdom Radiol (NY) · November 2018 PURPOSE: To assess the non-inferiority of dual-layer spectral detector CT (SDCT) compared to dual-source dual-energy CT (dsDECT) in discriminating uric acid (UA) from non-UA stones. METHODS: Fifty-seven extracted urinary calculi were placed in a cylindrica ... Full text Link to item Cite

Do Urinary Cystine Parameters Predict Clinical Stone Activity?

Journal Article J Urol · February 2018 PURPOSE: An accurate urinary predictor of stone recurrence would be clinically advantageous for patients with cystinuria. A proprietary assay (Litholink, Chicago, Illinois) measures cystine capacity as a potentially more reliable estimate of stone forming ... Full text Link to item Cite

Validation and Reliability of the Wisconsin Stone Quality of Life Questionnaire.

Journal Article J Urol · May 2017 PURPOSE: WISQOL (Wisconsin Stone Quality of Life questionnaire) is a disease specific, health related quality of life measure designed for patients who form kidney stones. The purpose of this study was to demonstrate the external and convergent validity of ... Full text Link to item Cite

The kidney stone and increased water intake trial in steel workers: results from a pilot study.

Journal Article Urolithiasis · April 2017 Preventing dehydration in subjects at risk may provide a means of primary prevention of kidney stones. The purpose of this pilot study was to assess the hydration status of an at-risk group of steel plant workers based on end-of-shift ('post-shift') spot u ... Full text Link to item Cite

A Novel Device to Prevent Stone Fragment Migration During Percutaneous Lithotripsy: Results from an In Vitro Kidney Model.

Journal Article J Endourol · November 2016 PURPOSE: We developed a polyethylene sack (the PercSac) that fits over the shaft of a rigid nephroscope and is deployed into the collecting system to capture a stone and contain fragments during percutaneous nephrolithotomy (PCNL). We previously reported o ... Full text Link to item Cite

Use of an Electronic Medical Record to Assess Patient-Reported Morbidity Following Ureteroscopy.

Journal Article J Endourol · May 2016 BACKGROUND AND PURPOSE: With the extensive documentation afforded by our electronic medical record (EMR), we observed an unusually high number of patient-initiated encounters following ureteroscopy (URS). We sought to quantify and categorize patient encoun ... Full text Link to item Cite

Innovations in surgical stone disease.

Journal Article Curr Opin Urol · May 2016 PURPOSE OF REVIEW: Urinary stone disease is a condition characterized by a rich history of surgical innovation. Herein, we review the new ideas, devices and methods that are the cornerstones of contemporary surgical innovation in stone disease, specificall ... Full text Link to item Cite

An Assessment of Patient Comfort and Morbidity After Robot-Assisted Radical Prostatectomy with Suprapubic Tube Versus Urethral Catheter Drainage.

Journal Article J Endourol · March 2016 OBJECTIVE: Robot-assisted laparoscopic prostatectomy (RALP) with suprapubic tube (SPT), compared to urethral catheter (UC) drainage, has been proposed to improve patient comfort and recovery. We sought to compare short-term outcomes for pain and morbidity ... Full text Link to item Cite

Ineffectiveness of remote ischemic renal preconditioning in a porcine solitary-kidney model.

Journal Article J Endourol · May 2015 PURPOSE: Our study sought to demonstrate the effects of remote ischemic preconditioning (R-IPC) on renal function in a large animal (porcine) solitary-kidney model. METHODS: Twelve pigs were assigned to two groups: Each underwent a right nephrectomy follow ... Full text Link to item Cite

Diet: from food to stone.

Journal Article World J Urol · February 2015 Dietary factors have been shown to influence urine composition and modulate the risk of kidney stone disease. With the rising prevalence of stone disease in many industrialized nations, dietary modification as therapy to improve lithogenic risk factors and ... Full text Link to item Cite

A prospective, multi-institutional study of flexible ureteroscopy for proximal ureteral stones smaller than 2 cm.

Journal Article J Urol · January 2015 PURPOSE: Flexible ureteroscopy is rapidly becoming a first line therapy for many patients with renal and ureteral stones. However, current understanding of treatment outcomes in patients with isolated proximal ureteral stones is limited. Therefore, we perf ... Full text Link to item Cite

A novel device to prevent stone fragment migration during percutaneous lithotripsy.

Journal Article J Endourol · December 2014 PURPOSE: We developed a novel device to capture stones in vivo in an enclosed bag (PercSac) to prevent dispersion of stone fragments during percutaneous nephrolithotomy (PCNL) or cystolitholapaxy. We report on our initial feasibility trials of the PercSac ... Full text Link to item Cite

Dietary calcium and prevention of calcium stones: More or less?

Chapter · November 1, 2014 Prevention of stone disease is the key to breaking the cycle of recurrence, patient suffering, and mounting costs. Dietary modifications are an attractive means to prevent stone formation because they are generally well tolerated and inexpensive. Although ... Full text Cite

Use of the National Health and Nutrition Examination Survey to calculate the impact of obesity and diabetes on cost and prevalence of urolithiasis in 2030.

Journal Article Eur Urol · October 2014 BACKGROUND: The prevalence of urolithiasis and its risk factors such as obesity and diabetes have increased over time. OBJECTIVE: Determine the future cost and prevalence of kidney stones using current and projected estimates for stones, obesity, diabetes, ... Full text Link to item Cite

Laparoscopic radiofrequency ablation of small renal tumors: long-term oncologic outcomes.

Journal Article J Endourol · March 2014 INTRODUCTION: Unlike percutaneous radiofrequency ablation (RFA) of small renal tumors, there are limited data assessing the long-term efficacy of laparoscopic RFA. Although the ablation cannot be visualized as reliably as with cryoablation, laparoscopic RF ... Full text Link to item Cite

Defining variation in urinary oxalate in hyperoxaluric stone formers.

Journal Article J Endourol · December 2013 BACKGROUND AND PURPOSE: The development of effective preventive therapy for renal calculi in patients with secondary hyperoxaluria (2°HO) relies on establishing the pattern of normal variation in urinary oxalate (uOx) and attempting to reduce it. Therefore ... Full text Link to item Cite

Laparoendoscopic single-site nephrectomy compared with conventional laparoscopic nephrectomy: a 5-year, single-surgeon experience.

Journal Article Eur Urol · September 2013 BACKGROUND: Conventional laparoscopic nephrectomy (LN) is the gold standard approach for nephrectomy. An advance in minimally invasive nephrectomy is laparoendoscopic single-site nephrectomy (LESS-N). OBJECTIVE: To compare 5-yr experience and outcomes of L ... Full text Link to item Cite

Resveratrol worsens survival in SCID mice with prostate cancer xenografts in a cell-line specific manner, through paradoxical effects on oncogenic pathways.

Journal Article Prostate · May 2013 BACKGROUND: Resveratrol increases lifespan and decreases the risk of many cancers. We hypothesized resveratrol will slow the growth of human prostate cancer xenografts. METHODS: SCID mice were fed Western diet (40% fat, 44% carbohydrate, 16% protein by kca ... Full text Link to item Cite

Androgenetic alopecia at various ages and prostate cancer risk in an equal-access multiethnic case-control series of veterans.

Conference Cancer Causes Control · May 2013 PURPOSE: Epidemiological data are conflicting regarding the association between androgenetic alopecia (AA) and prostate cancer (CaP). We examined the relationship between these two conditions. MATERIALS AND METHODS: We performed a case-control study at a V ... Full text Link to item Cite

Association between exercise and primary incidence of prostate cancer: does race matter?

Journal Article Cancer · April 1, 2013 BACKGROUND: Exercise is a modifiable lifestyle risk factor associated with prostate cancer risk reduction. However, whether this association is different as a function of race is unclear. In the current study, the authors attempted to characterize the link ... Full text Link to item Cite

Advances in percutaneous nephrolithotomy.

Journal Article Urol Clin North Am · February 2013 Percutaneous nephrolithotomy (PCNL) is the most morbid of the minimally invasive surgeical procedures for stone removal. Over the last 2 decades, refinements in technique and new technology have improved the efficacy and the efficiency of the procedure. Al ... Full text Link to item Cite

Improving shockwave lithotripsy outcomes

Chapter · January 1, 2013 Shockwave lithotripsy (SWL) is one of the most consistently utilized procedures for the treatment of upper urinary tract stones. SWL was initially applied widely as a treatment for upper tract stones until the limitations of the technology became apparent. ... Full text Cite

Exercise modulation of the host-tumor interaction in an orthotopic model of murine prostate cancer.

Journal Article J Appl Physiol (1985) · July 2012 The purpose of this study is to investigate the effects of exercise on cancer progression, metastasis, and underlying mechanisms in an orthotopic model of murine prostate cancer. C57BL/6 male mice (6-8 wk of age) were orthotopically injected with transgeni ... Full text Link to item Cite

Bladder augmentation versus urinary diversion in patients with spina bifida in the United States.

Journal Article J Urol · July 2011 PURPOSE: Augmentation cystoplasty has replaced urinary diversion as the cornerstone of surgical management of refractory neurogenic bladder in patients with spina bifida. Other than single institution series little is known about practice patterns of bladd ... Full text Link to item Cite

Effect of intermittent fasting on prostate cancer tumor growth in a mouse model.

Journal Article Prostate Cancer Prostatic Dis · December 2010 Caloric restriction (CR) has been shown to have anti-cancer properties. However, CR may be difficult to apply in humans secondary to compliance and potentially deleterious effects. An alternative is intermittent CR, or in the extreme case intermittent fast ... Full text Link to item Cite

Association of cigarette smoking with interval to biochemical recurrence after radical prostatectomy: results from the SEARCH database.

Journal Article Urology · November 2010 OBJECTIVES: To analyze the association between cigarette smoking and biochemical recurrence (BCR) after radical prostatectomy among men from the Shared Equal Access Regional Cancer Hospital (SEARCH) cohort. METHODS: We performed a retrospective analysis of ... Full text Link to item Cite

Low-carbohydrate diets and prostate cancer: how low is "low enough"?

Journal Article Cancer Prev Res (Phila) · September 2010 Previous studies indicate that carbohydrate intake influences prostate cancer biology, as mice fed a no-carbohydrate ketogenic diet (NCKD) had significantly smaller xenograft tumors and longer survival than mice fed a Western diet. As it is nearly impossib ... Full text Link to item Cite

Effect of isocaloric low fat diet on prostate cancer xenograft progression in a hormone deprivation model.

Journal Article J Urol · April 2010 PURPOSE: Previous mouse studies suggesting that low fat diets slow prostate cancer growth often used corn oil (omega-6), which enhances prostate cancer growth, as the primary fat. Using a saturated fat based diet we previously found no significant differen ... Full text Link to item Cite

Exercise and prostate cancer risk in a cohort of veterans undergoing prostate needle biopsy.

Journal Article J Urol · November 2009 PURPOSE: Epidemiological and molecular evidence suggest potential associations between exercise and prostate cancer risk reduction. We further characterized this relationship by examining exercise and cancer risk among men undergoing prostate needle biopsy ... Full text Link to item Cite

Exercise therapy across the prostate cancer continuum.

Journal Article Prostate Cancer Prostatic Dis · 2009 Exercise has been increasingly investigated as an adjunct therapy for cancer patients. The purpose of this paper is to comprehensively review the literature regarding exercise as a therapeutic adjunct for prostate cancer (PC). Several studies in patients w ... Full text Link to item Cite

Prostate-specific antigen screening among young men in the United States.

Journal Article Cancer · September 15, 2008 BACKGROUND: Disagreement exists on the use of prostate-specific antigen (PSA) tests for cancer-risk stratification in young men in the United States. Little is known about the use of PSA testing in these men. To understand policy implications of risk strat ... Full text Link to item Cite

Endothelin-receptor blockade mitigates the adverse effect of preretrieval warm ischemia on posttransplantation renal function in rats.

Journal Article Transplantation · May 27, 2003 BACKGROUND: Ischemia-reperfusion injury has been established as a nonimmunologic risk factor for the development of chronic graft nephropathy after renal transplantation. This objective of this study was to determine if oral administration of an endothelin ... Full text Link to item Cite

Endothelin receptor blockade during hypothermic perfusion preservation mitigates the adverse effect of preretrieval warm ischemic injury on posttransplant glomerular filtration rate.

Journal Article Transplantation · July 27, 2002 BACKGROUND: Preretrieval warm ischemic injury predisposes to both short-term and long-term dysfunction of cadaveric renal allografts. We previously reported that the excretion of the vasoactive peptide, endothelin (ET), is significantly increased during hy ... Full text Link to item Cite