Joel Meyer | Scholars@Duke

Joel Meyer
Truman and Nellie Semans/Alex Brown and Sons Associate Professor of Molecular Environmental Toxicology

Dr. Meyer studies the effects of toxic agents and stressors on human and wildlife health. He is particularly interested in understanding the mechanisms by which environmental agents cause DNA damage, the molecular processes that organisms employ to protect prevent and repair DNA damage, and genetic differences that may lead to increased or decreased sensitivity to DNA damage. Mitochondrial DNA damage and repair, as well as mitochondrial function in general, are a particular focus. He studies these effects in the nematode Caenorhabditis elegans, in cell culture, and collaboratively in other laboratory model organisms as well as in human populations in the USA and globally.

Current Appointments & Affiliations

Truman and Nellie Semans/Alex Brown and Sons Associate Professor of Molecular Environmental Toxicology, Environmental Sciences and Policy, Nicholas School of the Environment 2017 - 2022
Associate Professor of Environmental Genomics in the Division of Environmental Sciences and Policy, Environmental Sciences and Policy, Nicholas School of the Environment 2014
Associate Professor in the Department of Civil and Environmental Engineering, Civil and Environmental Engineering, Pratt School of Engineering 2015
Faculty Network Member of The Energy Initiative, Duke University Energy Initiative, Initiatives 2012
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2013
Affiliate, Duke Global Health Institute, Duke Global Health Institute, University Institutes and Centers 2017

Contact Information

A354 Lev Sci Res Ctr, Durham, NC 27708
Box 90328, Durham, NC 27708-0328
joel.meyer@duke.edu (919) 613-8109

Background
Education, Training, & Certifications
- Ph.D., Duke University 2003
- B.S., Juniata College 1992
Duke Appointment History
- Director of Graduate Studies of the Environmental Science Graduate Program, Environmental Sciences and Policy, Nicholas School of the Environment 2013 - 2016
- Assistant Professor of Environmental Genomics, Environmental Sciences and Policy, Nicholas School of the Environment 2007 - 2014
- Assist Professor in the Department of Civil and Environmental Engineering, Civil and Environmental Engineering, Pratt School of Engineering 2009 - 2012
Recognition
In the News
- NOV 3, 2017 Nicholas School of the Environment
  
  From Clean Up To Cutting Edge Research
- APR 18, 2017
  
  Five Faculty Named Bass Fellows for Excellence in Teaching and Research
- AUG 5, 2014
  
  Study Eyes Health Risks Of Drilling And Mining In Peru
Expertise
Subject Headings
Global Scholarship
- Research
Research
Selected Grants
- Does exposure to mitochondrial toxicants during germ cell development result in lifelong alterations in mitochondrial function mediated by epigenetic changes? awarded by National Institutes of Health 2017 - 2022
- GW150184 Mitochondrial dysfunction and Gulf War Illness awarded by United States Army Medical Research Acquisition Activity 2016 - 2019
- Center for Environmental Implications of Nanotechnology awarded by National Science Foundation 2008 - 2019
- Role of Mitochondrial CYP2E1 in Chemical Exposure-Driven Neurodegeneration awarded by National Institutes of Health 2016 - 2019
- Are mitochondria a major target of antimicrobial silver nanoparticles? awarded by National Institutes of Health 2017 - 2019
- Cooperative Program in Nanomaterials Hazard and Exposure Assessment Traineeships (NanoHEAT) awarded by Environmental Protection Agency 2015 - 2018
- IPA for Ian Ryde awarded by VA New Jersey Health Care System 2017 - 2018
- Duke University Program in Environmental Health awarded by National Institute of Environmental Health Sciences 2013 - 2018
- REU Site: Research Experiences for Undergraduates in Environmental Implications of Nanotechnology awarded by National Science Foundation 2014 - 2018
- Fluoride and human health: Assessing novel biomarkers in detecting bone disorder awarded by National Institutes of Health 2015 - 2017
- Genetic sensitivity to mitochondrial toxicity awarded by National Institutes of Health 2016 - 2017
- The Role of Mitochondrial DNA Damage in Neurodegeneration awarded by National Institutes of Health 2011 - 2017
- REU Site: Research Experience for Undergraudates on Environmental Implications of Nanotechnology at Duke, Carnegie Mello awarded by National Science Foundation 2010 - 2014
- COPAS BIOSORT Worm Sorter awarded by National Institutes of Health 2009 - 2010
Publications & Artistic Works
Selected Publications
- Conference Papers
  - Leuthner, T, Keith, NR, Jackson, C, Meyer, JN, and Shaw, JR. "Adaptation to cadmium reveals mechanism and susceptibility to mitochondrial genotoxicity." September 2017. Link to Item
  - Bess, AS, Crocker, TL, Ryde, IT, and Meyer, JN. "Mitochondrial Dynamics and Autophagy Aid in Removal of Persistent Mitochondrial DNA Damage." October 2011. Link to Item
  - Bess, AS, Crocker, TL, and Meyer, JN. "Mitochondrial Fusion and Autophagy Aid in Removal of Helix-Distorting Mitochondrial DNA Damage." August 2010. Link to Item
  - Meyer, JN, Jung, D, and Di Giulio, RT. "Quantifying Mitochondrial and Nuclear DNA Damage in Sentinel Species." August 2010. Link to Item
  - Meyer, JN, Arrant, AE, Bernal, AJ, Leung, MC-K, and Crocker, TL. "The use of c. elegans to study mitochondrial DNA damage, Fission/Fusion events and autophagy." August 2008. Link to Item
  - Meyer, JN, Boyd, WA, Haugen, AC, Freedman, JH, and Van Houten, B. "A caenorhabditis elegans model of Friedreich's ataxia shows iron sensitivity, mitochondrial DNA damage, and altered gene expression." 2004. Link to Item
- Journal Articles
  - Meyer, JN, Hartman, JH, and Mello, DF. "Mitochondrial Toxicity." Toxicological sciences : an official journal of the Society of Toxicology 162, no. 1 (March 2018): 15-23. Full Text Open Access Copy
  - Luz, AL, Kassotis, CD, Stapleton, HM, and Meyer, JN. "The high-production volume fungicide pyraclostrobin induces triglyceride accumulation associated with mitochondrial dysfunction, and promotes adipocyte differentiation independent of PPARγ activation, in 3T3-L1 cells." Toxicology 393 (January 2018): 150-159. Full Text
  - Meyer, JN, Leuthner, TC, and Luz, AL. "Mitochondrial fusion, fission, and mitochondrial toxicity." Toxicology 391 (November 2017): 42-53. (Review) Full Text
  - Meyer, JN, and Chan, SSL. "Sources, mechanisms, and consequences of chemical-induced mitochondrial toxicity." Toxicology 391 (November 2017): 2-4. Full Text
  - Chen, Y, Meyer, JN, Hill, HZ, Lange, G, Condon, MR, Klein, JC, Ndirangu, D, and Falvo, MJ. "Correction: Role of mitochondrial DNA damage and dysfunction in veterans with Gulf War Illness." PLOS ONE 12, no. 10 (October 16, 2017): e0186711-e0186711. Full Text
  - Gonzalez-Moragas, L, Maurer, LL, Harms, VM, Meyer, JN, Laromaine, A, and Roig, A. "Materials and toxicological approaches to study metal and metal-oxide nanoparticles in the model organism Caenorhabditis elegans." Materials horizons 4, no. 5 (September 2017): 719-746. Full Text
  - Hartman, JH, Kozal, JS, Di Giulio, RT, and Meyer, JN. "Zebrafish have an ethanol-inducible hepatic 4-nitrophenol hydroxylase that is not CYP2E1-like." Environmental toxicology and pharmacology 54 (September 2017): 142-145. Full Text
  - Luz, AL, Godebo, TR, Smith, LL, Leuthner, TC, Maurer, LL, and Meyer, JN. "Deficiencies in mitochondrial dynamics sensitize Caenorhabditis elegans to arsenite and other mitochondrial toxicants by reducing mitochondrial adaptability." Toxicology 387 (July 2017): 81-94. Full Text
  - Weinstein, JR, Asteria-Peñaloza, R, Diaz-Artiga, A, Davila, G, Hammond, SK, Ryde, IT, Meyer, JN, Benowitz, N, and Thompson, LM. "Exposure to polycyclic aromatic hydrocarbons and volatile organic compounds among recently pregnant rural Guatemalan women cooking and heating with solid fuels." International journal of hygiene and environmental health 220, no. 4 (June 2017): 726-735. Full Text
  - Wyatt, LH, Luz, AL, Cao, X, Maurer, LL, Blawas, AM, Aballay, A, Pan, WKY, and Meyer, JN. "Effects of methyl and inorganic mercury exposure on genome homeostasis and mitochondrial function in Caenorhabditis elegans." DNA repair 52 (April 2017): 31-48. Full Text
  - Chen, Y, Meyer, JN, Hill, HZ, Lange, G, Condon, MR, Klein, JC, Ndirangu, D, and Falvo, MJ. "Role of mitochondrial DNA damage and dysfunction in veterans with Gulf War Illness." PloS one 12, no. 9 (January 2017): e0184832-. Full Text
  - Hartman, JH, Miller, GP, and Meyer, JN. "Toxicological Implications of Mitochondrial Localization of CYP2E1." Toxicology research 6, no. 3 (January 2017): 273-289. Full Text
  - Lewis, JJ, Hollingsworth, JW, Chartier, RT, Cooper, EM, Foster, WM, Gomes, GL, Kussin, PS, MacInnis, JJ, Padhi, BK, Panigrahi, P, Rodes, CE, Ryde, IT, Singha, AK, Stapleton, HM, Thornburg, J, Young, CJ, Meyer, JN, and Pattanayak, SK. "Biogas Stoves Reduce Firewood Use, Household Air Pollution, and Hospital Visits in Odisha, India." Environmental science & technology 51, no. 1 (January 2017): 560-569. Full Text
  - Luz, AT, Godebo, TR, Bhatt, DP, Ilkayeva, OR, Maurer, LL, Hirschey, MD, and Meyer, JN. "Arsenite Uncouples Mitochondrial Respiration and Induces a Warburg-Like Effect in Caenorhabditis elegans." Toxicological sciences : an official journal of the Society of Toxicology 154, no. 1 (November 2016): 195-. Full Text
  - Santa-Gonzalez, GA, Gomez-Molina, A, Arcos-Burgos, M, Meyer, JN, and Camargo, M. "Distinctive adaptive response to repeated exposure to hydrogen peroxide associated with upregulation of DNA repair genes and cell cycle arrest." Redox biology 9 (October 2016): 124-133. Full Text
  - Luz, AL, and Meyer, JN. "Effects of reduced mitochondrial DNA content on secondary mitochondrial toxicant exposure in Caenorhabditis elegans." Mitochondrion 30 (September 2016): 255-264. Full Text
  - Maurer, LL, Yang, X, Schindler, AJ, Taggart, RK, Jiang, C, Hsu-Kim, H, Sherwood, DR, and Meyer, JN. "Intracellular trafficking pathways in silver nanoparticle uptake and toxicity in Caenorhabditis elegans." Nanotoxicology 10, no. 7 (September 2016): 831-835. Full Text
  - Luz, AL, Godebo, TR, Bhatt, DP, Ilkayeva, OR, Maurer, LL, Hirschey, MD, and Meyer, JN. "From the Cover: Arsenite Uncouples Mitochondrial Respiration and Induces a Warburg-like Effect in Caenorhabditis elegans." Toxicological sciences : an official journal of the Society of Toxicology 152, no. 2 (August 2016): 349-362. Full Text Open Access Copy
  - Luz, AL, Lagido, C, Hirschey, MD, and Meyer, JN. "In Vivo Determination of Mitochondrial Function Using Luciferase-Expressing Caenorhabditis elegans: Contribution of Oxidative Phosphorylation, Glycolysis, and Fatty Acid Oxidation to Toxicant-Induced Dysfunction." Current protocols in toxicology 69 (August 2016): 25.8.1-25.8.22. Full Text
  - Wyatt, LH, Diringer, SE, Rogers, LA, Hsu-Kim, H, Pan, WK, and Meyer, JN. "Antagonistic Growth Effects of Mercury and Selenium in Caenorhabditis elegans Are Chemical-Species-Dependent and Do Not Depend on Internal Hg/Se Ratios." Environmental science & technology 50, no. 6 (March 3, 2016): 3256-3264. Full Text Open Access Copy
  - "Erratum." Autophagy 12, no. 2 (February 2016): 443-443. Full Text
  - Gonzalez-Hunt, CP, Rooney, JP, Ryde, IT, Anbalagan, C, Joglekar, R, and Meyer, JN. "PCR-Based Analysis of Mitochondrial DNA Copy Number, Mitochondrial DNA Damage, and Nuclear DNA Damage." Current protocols in toxicology 67 (February 2016): 20.11.1-20.11.25. Full Text Open Access Copy
  - Maurer, LL, and Meyer, JN. "A systematic review of evidence for silver nanoparticle-induced mitochondrial toxicity." Environmental Science: Nano 3, no. 2 (2016): 311-322. Full Text Open Access Copy
  - Van Houten, B, Hunter, SE, and Meyer, JN. "Mitochondrial DNA damage induced autophagy, cell death, and disease." Frontiers in bioscience (Landmark edition) 21 (January 2016): 42-54. (Review) Full Text Open Access Copy
  - Luz, AL, Smith, LL, Rooney, JP, and Meyer, JN. "Seahorse Xfe 24 Extracellular Flux Analyzer-Based Analysis of Cellular Respiration in Caenorhabditis elegans." Current protocols in toxicology 66 (November 2, 2015): 25.7.1-25.715. Full Text
  - Maurer, LL, Ryde, IT, Yang, X, and Meyer, JN. "Caenorhabditis elegans as a Model for Toxic Effects of Nanoparticles: Lethality, Growth, and Reproduction." Current protocols in toxicology 66 (November 2, 2015): 20.10.1-20.1025. Full Text
  - Gorka, DE, Osterberg, JS, Gwin, CA, Colman, BP, Meyer, JN, Bernhardt, ES, Gunsch, CK, DiGulio, RT, and Liu, J. "Reducing Environmental Toxicity of Silver Nanoparticles through Shape Control." Environmental science & technology 49, no. 16 (August 2015): 10093-10098. Full Text
  - Robey, RB, Weisz, J, Kuemmerle, NB, Salzberg, AC, Berg, A, Brown, DG, Kubik, L, Palorini, R, Al-Mulla, F, Al-Temaimi, R, Colacci, A, Mondello, C, Raju, J, Woodrick, J, Scovassi, AI, Singh, N, Vaccari, M, Roy, R, Forte, S, Memeo, L, Salem, HK, Amedei, A, Hamid, RA, Williams, GP, Lowe, L, Meyer, J, Martin, FL, Bisson, WH, Chiaradonna, F, and Ryan, EP. "Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?." Carcinogenesis 36 Suppl 1 (June 2015): S203-S231. (Review) Full Text
  - Bone, AJ, Matson, CW, Colman, BP, Yang, X, Meyer, JN, and Di Giulio, RT. "Silver nanoparticle toxicity to Atlantic killifish (Fundulus heteroclitus) and Caenorhabditis elegans: a comparison of mesocosm, microcosm, and conventional laboratory studies." Environmental toxicology and chemistry 34, no. 2 (February 2015): 275-282. Full Text
  - Jayasundara, N, Van Tiem Garner, L, Meyer, JN, Erwin, KN, and Di Giulio, RT. "AHR2-Mediated transcriptomic responses underlying the synergistic cardiac developmental toxicity of PAHs." Toxicological sciences : an official journal of the Society of Toxicology 143, no. 2 (February 2015): 469-481. Full Text
  - Luz, AL, Rooney, JP, Kubik, LL, Gonzalez, CP, Song, DH, and Meyer, JN. "Mitochondrial Morphology and Fundamental Parameters of the Mitochondrial Respiratory Chain Are Altered in Caenorhabditis elegans Strains Deficient in Mitochondrial Dynamics and Homeostasis Processes." PloS one 10, no. 6 (January 2015): e0130940-. Full Text
  - Rooney, JP, Ryde, IT, Sanders, LH, Howlett, EH, Colton, MD, Germ, KE, Mayer, GD, Greenamyre, JT, and Meyer, JN. "PCR based determination of mitochondrial DNA copy number in multiple species." Methods in molecular biology (Clifton, N.J.) 1241 (January 2015): 23-38. Full Text
  - Shaughnessy, DT, McAllister, K, Worth, L, Haugen, AC, Meyer, JN, Domann, FE, Van Houten, B, Mostoslavsky, R, Bultman, SJ, Baccarelli, AA, Begley, TJ, Sobol, RW, Hirschey, MD, Ideker, T, Santos, JH, Copeland, WC, Tice, RR, Balshaw, DM, and Tyson, FL. "Mitochondria, energetics, epigenetics, and cellular responses to stress." Environmental health perspectives 122, no. 12 (December 2014): 1271-1278. (Review) Full Text
  - Rooney, JP, Ryde, IT, Sanders, LH, Howlett, EH, Colton, MD, Germ, KE, Mayer, GD, Greenamyre, JT, and Meyer, JN. "PCR based determination of mitochondrial DNA copy number in multiple species." (October 11, 2014): 23-38. (Chapter) Full Text
  - Ahn, J-M, Eom, H-J, Yang, X, Meyer, JN, and Choi, J. "Comparative toxicity of silver nanoparticles on oxidative stress and DNA damage in the nematode, Caenorhabditis elegans." Chemosphere 108 (August 2014): 343-352. Full Text
  - Colton, MD, Kwok, KWH, Brandon, JA, Warren, IH, Ryde, IT, Cooper, EM, Hinton, DE, Rittschof, D, and Meyer, JN. "Developmental toxicity and DNA damage from exposure to parking lot runoff retention pond samples in the Japanese medaka (Oryzias latipes)." Marine environmental research 99 (August 2014): 117-124. Full Text
  - Rooney, JP, Luz, AL, González-Hunt, CP, Bodhicharla, R, Ryde, IT, Anbalagan, C, and Meyer, JN. "Effects of 5'-fluoro-2-deoxyuridine on mitochondrial biology in Caenorhabditis elegans." Experimental gerontology 56 (August 2014): 69-76. Full Text
  - Sendoel, A, Maida, S, Zheng, X, Teo, Y, Stergiou, L, Rossi, C-A, Subasic, D, Pinto, SM, Kinchen, JM, Shi, M, Boettcher, S, Meyer, JN, Manz, MG, Bano, D, and Hengartner, MO. "DEPDC1/LET-99 participates in an evolutionarily conserved pathway for anti-tubulin drug-induced apoptosis." Nature cell biology 16, no. 8 (August 2014): 812-820. Full Text
  - Levard, C, Yang, X, Meyer, JN, and Lowry, GV. "Response to Comment on “Sulfidation of Silver Nanoparticles: Natural Antidote to Their Toxicity”." Environmental Science & Technology 48, no. 10 (May 20, 2014): 6051-6052. Full Text
  - Yang, X, Jiang, C, Hsu-Kim, H, Badireddy, AR, Dykstra, M, Wiesner, M, Hinton, DE, and Meyer, JN. "Silver nanoparticle behavior, uptake, and toxicity in Caenorhabditis elegans: effects of natural organic matter." Environmental science & technology 48, no. 6 (March 10, 2014): 3486-3495. Full Text
  - Ahn, JM, Eom, HJ, Yang, X, Meyer, JN, and Choi, J. "Comparative toxicity of silver nanoparticles on oxidative stress and DNA damage in the nematode, Caenorhabditis elegans." Chemosphere 108 (January 1, 2014): 343-352. Full Text
  - Bodhicharla, R, Ryde, IT, Prasad, GL, and Meyer, JN. "The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces mitochondrial and nuclear DNA damage in Caenorhabditis elegans." Environ Mol Mutagen 55, no. 1 (January 2014): 43-50. Full Text Link to Item
  - Choi, J, Tsyusko, OV, Unrine, JM, Chatterjee, N, Ahn, J-M, Yang, X, Thornton, BL, Ryde, IT, Starnes, D, and Meyer, JN. "A micro-sized model for the in vivo study of nanoparticle toxicity: what has Caenorhabditis elegans taught us?." Environmental Chemistry 11, no. 3 (2014): 227-227. Full Text
  - Colton, MD, Kwok, KWH, Brandon, JA, Warren, IH, Ryde, IT, Cooper, EM, Hinton, DE, Rittschof, D, and Meyer, JN. "Developmental toxicity and DNA damage from exposure to parking lot runoff retention pond samples in the Japanese medaka (Oryzias latipes)." Marine Environmental Research 99 (January 1, 2014): 117-124. Full Text
  - Furda, A, Santos, JH, Meyer, JN, and Van Houten, B. "Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells." Methods in molecular biology (Clifton, N.J.) 1105 (January 2014): 419-437. Full Text
  - González-Hunt, CP, Leung, MCK, Bodhicharla, RK, McKeever, MG, Arrant, AE, Margillo, KM, Ryde, IT, Cyr, DD, Kosmaczewski, SG, Hammarlund, M, and Meyer, JN. "Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans." PloS one 9, no. 12 (January 2014): e114459-. Full Text
  - Rand, AA, Rooney, JP, Butt, CM, Meyer, JN, and Mabury, SA. "Cellular toxicity associated with exposure to perfluorinated carboxylates (PFCAs) and their metabolic precursors." Chemical research in toxicology 27, no. 1 (January 2014): 42-50. Full Text
  - Rooney, JP, Luz, AL, González-Hunt, CP, Bodhicharla, R, Ryde, IT, Anbalagan, C, and Meyer, JN. "Effects of 5'-fluoro-2-deoxyuridine on mitochondrial biology in Caenorhabditis elegans." Experimental Gerontology 56 (January 1, 2014): 69-76. Full Text
  - Sendoel, A, Maida, S, Zheng, X, Teo, Y, Stergiou, L, Rossi, CA, Subasic, D, Pinto, SM, Kinchen, JM, Shi, M, Boettcher, S, Meyer, JN, Manz, MG, Bano, D, and Hengartner, MO. "DEPDC1/LET-99 participates in an evolutionarily conserved pathway for anti-tubulin drug-induced apoptosis." Nature Cell Biology 16, no. 8 (January 1, 2014): 812-820. Full Text
  - Rooney, JP, Bodhicharla, R, Bess, AS, Leung, MCK, Ryde, IT, Ji, AQ, and Meyer, JN. "Developmental exposure to ultraviolet C radiation results in altered energy production later in life in Caenorhabditis elegans." MITOCHONDRION 13, no. 6 (November 2013): 922-922. Full Text Link to Item
  - Arnold, MC, Badireddy, AR, Wiesner, MR, Di Giulio, RT, and Meyer, JN. "Cerium oxide nanoparticles are more toxic than equimolar bulk cerium oxide in Caenorhabditis elegans." Arch Environ Contam Toxicol 65, no. 2 (August 2013): 224-233. Full Text Link to Item
  - Leung, MCK, Rooney, JP, Ryde, IT, Bernal, AJ, Bess, AS, Crocker, TL, Ji, AQ, and Meyer, JN. "Effects of early life exposure to ultraviolet C radiation on mitochondrial DNA content, transcription, ATP production, and oxygen consumption in developing Caenorhabditis elegans." BMC PHARMACOLOGY & TOXICOLOGY 14 (February 4, 2013). Full Text Link to Item
  - Arnold, MC, Badireddy, AR, Wiesner, MR, Giulio, RTD, and Meyer, JN. "Cerium oxide nanoparticles are more toxic than equimolar bulk cerium oxide in caenorhabditis elegans." Archives of Environmental Contamination and Toxicology 65, no. 2 (2013): 224-233. Full Text
  - Bess, AS, Leung, MCK, Ryde, IT, Rooney, JP, Hinton, DE, and Meyer, JN. "Effects of mutations in mitochondrial dynamics-related genes on the mitochondrial response to ultraviolet C radiation in developing Caenorhabditis elegans." Worm 2, no. 1 (January 1, 2013): e23763-. Full Text Link to Item
  - Bess, AS, Ryde, IT, Hinton, DE, and Meyer, JN. "UVC-induced mitochondrial degradation via autophagy correlates with mtDNA damage removal in primary human fibroblasts." J Biochem Mol Toxicol 27, no. 1 (January 2013): 28-41. Full Text Link to Item
  - Bess, AS, Ryde, IT, Hinton, DE, and Meyer, JN. "UVC-Induced Mitochondrial Degradation via Autophagy Correlates with mtDNA Damage Removal in Primary Human Fibroblasts." Journal of Biochemical and Molecular Toxicology 27, no. 1 (2013): 28-41. Full Text
  - Levard, C, Hotze, EM, Colman, BP, Dale, AL, Truong, L, Yang, XY, Bone, AJ, Brown, GE, Tanguay, RL, Di Giulio, RT, Bernhardt, ES, Meyer, JN, Wiesner, MR, and Lowry, GV. "Sulfidation of silver nanoparticles: natural antidote to their toxicity." Environ Sci Technol 47, no. 23 (2013): 13440-13448. Full Text Link to Item
  - Meyer, JN, Leung, MCK, Rooney, JP, Sendoel, A, Hengartner, MO, Kisby, GE, and Bess, AS. "Mitochondria as a target of environmental toxicants." Toxicological Sciences 134, no. 1 (2013): 1-17. Full Text
  - Turner, EA, Kroeger, GL, Arnold, MC, Thornton, BL, Di Giulio, RT, and Meyer, JN. "Assessing different mechanisms of toxicity in mountaintop removal/valley fill coal mining-affected watershed samples using Caenorhabditis elegans. (Published online)" PLoS One 8, no. 9 (2013): e75329-. Full Text Link to Item
  - Yang, X, Gondikas, AP, Marinakos, SM, Auffan, M, Liu, J, Hsu-Kim, H, and Meyer, JN. "Mechanism of silver nanoparticle toxicity is dependent on dissolved silver and surface coating in Caenorhabditis elegans." Environ Sci Technol 46, no. 2 (January 17, 2012): 1119-1127. Full Text Link to Item
  - Bess, AS, Crocker, TL, Ryde, IT, and Meyer, JN. "Mitochondrial dynamics and autophagy aid in removal of persistent mitochondrial DNA damage in Caenorhabditis elegans." Nucleic Acids Research 40, no. 16 (2012): 7916-7931. Full Text
  - Brar, SS, Meyer, JN, Bortner, CD, Houten, BV, and II, WJM. "Mitochondrial DNA-depleted A549 cells are resistant to bleomycin." American Journal of Physiology - Lung Cellular and Molecular Physiology 303, no. 5 (2012): L413-L424. Full Text
  - Furda, AM, Bess, AS, Meyer, JN, and Houten, BV. "Analysis of DNA damage and repair in nuclear and mitochondrial DNA of animal cells using quantitative PCR." Methods in Molecular Biology 920 (2012): 111-132. Full Text
  - Hunter, SE, Gustafson, MA, Margillo, KM, Lee, SA, Ryde, IT, and Meyer, JN. "In vivo repair of alkylating and oxidative DNA damage in the mitochondrial and nuclear genomes of wild-type and glycosylase-deficient Caenorhabditis elegans." DNA Repair 11, no. 11 (2012): 857-863. Full Text
  - Kasiviswanathan, R, Gustafson, MA, Copeland, WC, and Meyer, JN. "Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers." Journal of Biological Chemistry 287, no. 12 (2012): 9222-9229. Full Text
  - Meyer, JN, and Bess, AS. "Involvement of autophagy and mitochondrial dynamics in determining the fate and effects of irreparable mitochondrial DNA damage." Autophagy 8, no. 12 (2012): 1822-1823. Full Text
  - Meyer, JN. "In vivo analysis of the ability of Caenorhabditis elegans to metabolize the human CYP3A and CYP1A2 diagnostic substrates testosterone and phenacetin (Accepted)." Worm Breeder's Gazette (2012). (Academic Article)
  - Meyer, JN. "A call for fuller reporting of toxicity test data (Accepted)." Integrated Environmental Assessment and Management (2012). (Academic Article)
  - Meyer, JN, Lord, CA, Yang, XY, Turner, EA, Badireddy, AR, Marinakos, SM, Chilkoti, A, Wiesner, MR, and Auffan, M. "Intracellular uptake and associated toxicity of silver nanoparticles in Caenorhabditis elegans." Aquat Toxicol 100, no. 2 (October 15, 2010): 140-150. Full Text Link to Item
  - Hunter, SE, Jung, D, Di Giulio, RT, and Meyer, JN. "The QPCR assay for analysis of mitochondrial DNA damage, repair, and relative copy number." Methods 51, no. 4 (August 2010): 444-451. (Review) Full Text Link to Item
  - Alexeyenko, A, Wassenberg, DM, Lobenhofer, EK, Yen, J, Linney, E, Sonnhammer, ELL, and Meyer, JN. "Dynamic zebrafish interactome reveals transcriptional mechanisms of dioxin toxicity." PLoS ONE 5, no. 5 (2010). Full Text Open Access Copy
  - Alexeyenko, A, Wassenberg, DM, Lobenhofer, EK, Yen, J, Linney, E, Sonnhammer, ELL, and Meyer, JN. "Dynamic zebrafish interactome reveals transcriptional mechanisms of dioxin toxicity." PloS one 5, no. 5 (2010): e10465-. Full Text
  - Alexeyenko, A, Wassenberg, DM, Lobenhofer, EK, Yen, J, Sonnhammer, ELL, Linney, E, and Meyer, JN. "Interactome-based analysis of the transcriptomic response to dioxin in developing zebrafish Danio rerio." PLoS ONE 5 (2010): e10465-. (Academic Article)
  - Boamah, EK, Brekman, A, Tomasz, M, Myeku, N, Figueiredo-Pereira, M, Hunter, S, Meyer, J, Bhosle, RC, and Bargonetti, J. "DNA adducts of decarbamoyl mitomycin C efficiently kill cells without wild-type p53 resulting from proteasome-mediated degradation of checkpoint protein 1." Chemical Research in Toxicology 23, no. 7 (2010): 1151-1162. Full Text Open Access Copy
  - Boyd, WA, Crocker, TL, Rodriguez, AM, Leung, MCK, Lehmann, DW, Freedman, JH, Houten, BV, and Meyer, JN. "Nucleotide excision repair genes are expressed at low levels and are not detectably inducible in Caenorhabditis elegans somatic tissues, but their function is required for normal adult life after UVC exposure." Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis 683, no. 1-2 (2010): 57-67. Full Text
  - Haugen, AC, Prospero, NAD, Parker, JS, Fannin, RD, Chou, J, Meyer, JN, Halweg, C, Collins, JB, Durr, A, Fischbeck, K, and Houten, BV. "Altered gene expression and DNA damage in peripheral blood cells from Friedreich's ataxia patients: Cellular model of pathology." PLoS Genetics 6, no. 1 (2010). Full Text Open Access Copy
  - Leung, MCK, Goldstone, JV, Boyd, WA, Freedman, JH, and Meyer, JN. "Caenorhabditis elegans generates biologically relevant levels of genotoxic metabolites from aflatoxin B₁ but not benzo[a]pyrene in vivo." Toxicological Sciences 118, no. 2 (2010): 444-453. Full Text
  - Meyer, JN, and Van Houten, B. "Apparently normal DNA repair and transcript expression in the RB885 strain carrying an intronic deletion in the xpc-1 gene." Worm Breeder's Gazette 18 (2010): 23-. (Academic Article)
  - Meyer, JN. "QPCR: A tool for analysis of mitochondrial and nuclear DNA damage in ecotoxicology." Ecotoxicology 19, no. 4 (2010): 804-811. Full Text
  - Jung, D, Cho, Y, Meyer, JN, and Di Giulio, RT. "The long amplicon quantitative PCR for DNA damage assay as a sensitive method of assessing DNA damage in the environmental model, Atlantic killifish (Fundulus heteroclitus)." Comp Biochem Physiol C Toxicol Pharmacol 149, no. 2 (March 2009): 182-186. Full Text Link to Item
  - Eischeid, AC, Meyer, JN, and Linden, KG. "UV disinfection of adenoviruses: Molecular indications of DNA damage efficiency." Applied and Environmental Microbiology 75, no. 1 (2009): 23-28. Full Text
  - Billiard, SM, Meyer, JN, Wassenberg, DM, Hodson, PV, and Di Giulio, RT. "Nonadditive effects of PAHs on Early Vertebrate Development: mechanisms and implications for risk assessment." Toxicol Sci 105, no. 1 (September 2008): 5-23. Full Text Link to Item
  - Jung, D, Meyer, JN, and Di Giulio, RT. "Effects of polycyclic aromatic hydrocarbons on mitochondrial DNA damage in the killifish (Fundulus heteroclitus)." MARINE ENVIRONMENTAL RESEARCH 66, no. 1 (July 2008): 32-32. Link to Item
  - Eischeid, AC, Meyer, JN, and Linden, KG. "DNA damage assessment in UV-treated adenovirus." Water Quality Technology Conference and Exposition 2008 (2008): 2968-2975.
  - Leung, MCK, Williams, PL, Benedetto, A, Au, C, Helmcke, KJ, Aschner, M, and Meyer, JN. "Caenorhabditis elegans: An emerging model in biomedical and environmental toxicology." Toxicological Sciences 106, no. 1 (2008): 5-28. Full Text
  - Burnett, KG, Bain, LJ, Baldwin, WS, Callard, GV, Cohen, S, Di Giulio, RT, Evans, DH, Gómez-Chiarri, M, Hahn, ME, Hoover, CA, Karchner, SI, Katoh, F, Maclatchy, DL, Marshall, WS, Meyer, JN, Nacci, DE, Oleksiak, MF, Rees, BB, Singer, TD, Stegeman, JJ, Towle, DW, Van Veld, PA, Vogelbein, WK, Whitehead, A, Winn, RN, and Crawford, DL. "Fundulus as the premier teleost model in environmental biology: opportunities for new insights using genomics." Comp Biochem Physiol Part D Genomics Proteomics 2, no. 4 (December 2007): 257-286. Full Text Link to Item
  - Chan, SSL, Santos, JH, Meyer, JN, Mandavilli, BS, Jr, DLC, McCash, CL, Kissling, GE, Nyska, A, Foley, JF, Houten, BV, Copeland, WC, Walker, VE, Witt, KL, and Bishop, JB. "Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination." Environmental and Molecular Mutagenesis 48, no. 3-4 (2007): 190-200. Full Text
  - Meyer, JN, Boyd, WA, Azzam, GA, Haugen, AC, Freedman, JH, and Houten, BV. "Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans." Genome Biology 8, no. 5 (2007). Full Text
  - Wielgus, AR, Chignell, CF, Miller, DS, Houten, BV, Meyer, J, Hu, D-N, and Roberts, JE. "Phototoxicity in human retinal pigment epithelial cells promoted by hypericin, a component of St. John's wort." Photochemistry and Photobiology 83, no. 3 (2007): 706-713. Full Text
  - Giulio, RD, Billiard, S, Meyer, J, Wassenberg, D, and Hodson, P. "Synergistic developmental toxicity of polycyclic aromatic hydrocarbons: Towards a mechanistic understanding." Marine Environmental Research 62, no. SUPPL. 1 (2006): S45-S46. Full Text
  - Santos, JH, Meyer, JN, Mandavilli, BS, and Houten, BV. "Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells." Methods in molecular biology (Clifton, N.J.) 314 (2006): 183-199.
  - Santos, JH, Meyer, JN, and Houten, BV. "Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptosis." Human Molecular Genetics 15, no. 11 (2006): 1757-1768. Full Text
  - Timme-Laragy, AR, Meyer, JN, Waterland, RA, and Di Giulio, RT. "Analysis of CpG methylation in the killifish CYP1A promoter." Comp Biochem Physiol C Toxicol Pharmacol 141, no. 4 (August 2005): 406-411. Full Text Link to Item
  - Meyer, JN, Volz, DC, Freedman, JH, and Di Giulio, RT. "Differential display of hepatic mRNA from killifish (Fundulus heteroclitus) inhabiting a Superfund estuary." Aquat Toxicol 73, no. 4 (July 30, 2005): 327-341. Full Text Link to Item
  - Santos, JH, Meyer, JN, Skorvaga, M, Annab, LA, and Houten, BV. "Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage." Aging Cell 3, no. 6 (2004): 399-411. Full Text
  - Meyer, JN, Smith, JD, Winston, GW, and Di Giulio, RT. "Antioxidant defenses in killifish (Fundulus heteroclitus) exposed to contaminated sediments and model prooxidants: short-term and heritable responses." Aquat Toxicol 65, no. 4 (December 10, 2003): 377-395. Link to Item
  - Meyer, JN, Wassenberg, DM, Karchner, SI, Hahn, ME, and Di Giulio, RT. "Expression and inducibility of aryl hydrocarbon receptor pathway genes in wild-caught killifish (Fundulus heteroclitus) with different contaminant-exposure histories." Environ Toxicol Chem 22, no. 10 (October 2003): 2337-2343. Link to Item
  - Meyer, JN, and Giulio, RTD. "Heritable adaptation and fitness costs in killifish (Fundulus heteroclitus) inhabiting a polluted estuary." Ecological Applications 13, no. 2 (2003): 490-503.
  - Meyer, J, and Di Giulio, R. "Patterns of heritability of decreased EROD activity and resistance to PCB 126-induced teratogenesis in laboratory-reared offspring of killifish (Fundulus heteroclitus) from a creosote-contaminated site in the Elizabeth River, VA, USA." Mar Environ Res 54, no. 3-5 (September 2002): 621-626. Link to Item
  - Meyer, JN, Nacci, DE, and Di Giulio, RT. "Cytochrome P4501A (CYP1A) in killifish (Fundulus heteroclitus): heritability of altered expression and relationship to survival in contaminated sediments." Toxicol Sci 68, no. 1 (July 2002): 69-81. Link to Item
  - Meyer, JN, MacLean, ED, and Giulio, RTD. "Increased sensitivity to oxidative stress in a creosote-adapted population of mummichog (Fundulus heteroclitus)." Marine Environmental Research 50, no. 1-5 (2000): 78--.
  - Keller, JM, Meyer, JN, Mattie, M, Augspurger, T, Rau, M, Dong, J, and Levin, ED. "Assessment of immunotoxicology in wild populations: Review and recommendations." Reviews in Toxicology 3, no. 1-4 (1999): 167-212.
- Other Articles
  - Klionsky, DJ, Abdelmohsen, K, Abe, A, Abedin, MJ, Abeliovich, H, Acevedo Arozena, A, Adachi, H, Adams, CM, Adams, PD, Adeli, K, Adhihetty, PJ, Adler, SG, Agam, G, Agarwal, R, Aghi, MK, Agnello, M, Agostinis, P, Aguilar, PV, Aguirre-Ghiso, J, Airoldi, EM, Ait-Si-Ali, S, Akematsu, T, Akporiaye, ET, Al-Rubeai, M, Albaiceta, GM, Albanese, C, Albani, D, Albert, ML, Aldudo, J, Algül, H, Alirezaei, M, Alloza, I, Almasan, A, Almonte-Beceril, M, Alnemri, ES, Alonso, C, Altan-Bonnet, N, and Altieri, DC et al. "Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)." Autophagy 12, no. 1 (January 2016): 1-222. Full Text
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