Journal ArticleBiocybernetics and Biomedical Engineering · April 1, 2024
Objective: Breathing elevated oxygen partial pressures (PO2) prior to SCUBA diving increases the risk of developing central nervous system oxygen toxicity (CNS-OT), which could impair performance or result in seizure and subsequent drowning. We aimed to st ...
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Journal ArticleAnnu Int Conf IEEE Eng Med Biol Soc · November 2021
The most effective method to mitigate decompression sickness in divers is hyperbaric oxygen (HBO2) pre-breathing. However, divers breathing HBO2 are at risk for developing central nervous system oxygen toxicity (CNS-OT), which can manifest as symptoms that ...
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Journal ArticleUndersea Hyperb Med · 2021
It is widely accepted that bubbles are a necessary but insufficient condition for the development of decompression sickness. However, open questions remain regarding the precise formation and behavior of these bubbles after an ambient pressure reduction (d ...
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Journal ArticleUndersea Hyperb Med · 2021
Venous gas emboli (VGE) are often quantified as a marker of decompression stress on echocardiograms. Bubble-counting has been proposed as an easy to learn method, but remains time-consuming, rendering large dataset analysis impractical. Computer automation ...
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Journal ArticleMed Sci Sports Exerc · September 2017
Swimming-induced pulmonary edema (SIPE) occurs during swimming and scuba diving, usually in cold water, in susceptible healthy individuals, especially military recruits and triathletes. We have previously demonstrated that pulmonary artery (PA) pressure an ...
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Journal ArticleOral Dis · March 2017
Osteonecrosis of the jaw may be caused by radiation, medication, or infection. Optimal therapy requires a multimodal approach that combines surgery with adjuvant treatments. This review focuses on the use of adjunctive hyperbaric oxygen therapy for this co ...
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Journal ArticleUndersea Hyperb Med · 2017
Carbon dioxide (CO₂) retention, or hypercapnia, is a known risk of diving that can cause mental and physical impairments leading to life-threatening accidents. Often, such accidents occur due to elevated inspired carbon dioxide. For instance, in cases of C ...
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Journal ArticleUndersea Hyperb Med · 2017
Rebreather diving has one of the highest fatality rates per man hour of any diving activity in the world. The leading cause of death is hypoxia, typically from equipment or procedural failures. Hypoxia causes very few symptoms prior to causing loss of cons ...
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Journal ArticleJ Appl Physiol (1985) · October 1, 2016
Diving narcosis results from the complex interaction of gases, activities, and environmental conditions. We hypothesized that these interactions could be separated into their component parts. Where previous studies have tested single cognitive tasks sequen ...
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Journal ArticleCirculation · March 8, 2016
BACKGROUND: Swimming-induced pulmonary edema (SIPE) occurs during swimming or scuba diving, often in young individuals with no predisposing conditions, and its pathophysiology is poorly understood. This study tested the hypothesis that pulmonary artery and ...
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Journal ArticleUndersea Hyperb Med · 2015
A hookah smoker who was treated for severe carbon monoxide poisoning with hyperbaric oxygen reported using a different type of charcoal prior to hospital admission, i.e., quick-light charcoal. This finding led to a study aimed at determining whether CO pro ...
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Journal ArticleHead Neck · December 2014
BACKGROUND: Hyperbaric oxygen (HBO) therapy induces native tissue oxygenation. The hypothesis was patients with mandibular osteoradionecrosis (ORN) and a history of HBO therapy would have less free flap reconstruction complications than patients without HB ...
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Journal ArticleIntensive Care Med · July 2012
PURPOSE: Necrotising soft tissue infection (NSTI) is a deadly disease associated with a significant risk of mortality and long-term disability from limb and tissue loss. The aim of this study was to determine the effect of hyperbaric oxygen (HBO(2)) therap ...
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Journal ArticleJ Oral Maxillofac Surg · July 2012
PURPOSE: This study tested hyperbaric oxygen (HBO) as an adjunct to surgery and antibiotics in the treatment of bisphosphonate-related osteonecrosis of the jaw (ONJ) and evaluated its effects on gingival healing, pain, and quality of life. MATERIALS AND ME ...
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Journal ArticleUndersea Hyperb Med · 2012
INTRODUCTION: Supplemental oxygen has been reported to cause pulmonary complications after bleomycin. We describe the safe administration of hyperbaric oxygen (HBO2) after bleomycin in 15 patients. METHODS: Paper and electronic records were reviewed for bl ...
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Journal ArticleJ Appl Physiol (1985) · March 2011
Hyperoxia has been shown to attenuate the increase in pulmonary artery (PA) pressure associated with immersed exercise in thermoneutral water, which could serve as a possible preventive strategy for the development of immersion pulmonary edema (IPE). We te ...
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Journal ArticleJ Appl Physiol (1985) · July 2010
Immersion pulmonary edema (IPE) can occur in otherwise healthy swimmers and divers, likely because of stress failure of pulmonary capillaries secondary to increased pulmonary vascular pressures. Prior studies have revealed progressive increase in ventilati ...
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Journal ArticleUndersea Hyperb Med · 2010
INTRODUCTION: It is unknown if the benefits of rapid treatment always outweigh the risks of emergency evacuation for recreational divers. To investigate current triage practice, we reviewed a three-year consecutive series of evacuations and analyzed the re ...
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Journal ArticleBiocybernetics and Biomedical Engineering · April 1, 2024
Objective: Breathing elevated oxygen partial pressures (PO2) prior to SCUBA diving increases the risk of developing central nervous system oxygen toxicity (CNS-OT), which could impair performance or result in seizure and subsequent drowning. We aimed to st ...
Full textCite
Journal ArticleAnnu Int Conf IEEE Eng Med Biol Soc · November 2021
The most effective method to mitigate decompression sickness in divers is hyperbaric oxygen (HBO2) pre-breathing. However, divers breathing HBO2 are at risk for developing central nervous system oxygen toxicity (CNS-OT), which can manifest as symptoms that ...
Full textLink to itemCite
Journal ArticleUndersea Hyperb Med · 2021
It is widely accepted that bubbles are a necessary but insufficient condition for the development of decompression sickness. However, open questions remain regarding the precise formation and behavior of these bubbles after an ambient pressure reduction (d ...
Full textLink to itemCite
Journal ArticleUndersea Hyperb Med · 2021
Venous gas emboli (VGE) are often quantified as a marker of decompression stress on echocardiograms. Bubble-counting has been proposed as an easy to learn method, but remains time-consuming, rendering large dataset analysis impractical. Computer automation ...
Full textLink to itemCite
Journal ArticleMed Sci Sports Exerc · September 2017
Swimming-induced pulmonary edema (SIPE) occurs during swimming and scuba diving, usually in cold water, in susceptible healthy individuals, especially military recruits and triathletes. We have previously demonstrated that pulmonary artery (PA) pressure an ...
Full textOpen AccessLink to itemCite
Journal ArticleOral Dis · March 2017
Osteonecrosis of the jaw may be caused by radiation, medication, or infection. Optimal therapy requires a multimodal approach that combines surgery with adjuvant treatments. This review focuses on the use of adjunctive hyperbaric oxygen therapy for this co ...
Full textLink to itemCite
Journal ArticleUndersea Hyperb Med · 2017
Carbon dioxide (CO₂) retention, or hypercapnia, is a known risk of diving that can cause mental and physical impairments leading to life-threatening accidents. Often, such accidents occur due to elevated inspired carbon dioxide. For instance, in cases of C ...
Full textOpen AccessLink to itemCite
Journal ArticleUndersea Hyperb Med · 2017
Rebreather diving has one of the highest fatality rates per man hour of any diving activity in the world. The leading cause of death is hypoxia, typically from equipment or procedural failures. Hypoxia causes very few symptoms prior to causing loss of cons ...
Full textOpen AccessLink to itemCite
Journal ArticleJ Appl Physiol (1985) · October 1, 2016
Diving narcosis results from the complex interaction of gases, activities, and environmental conditions. We hypothesized that these interactions could be separated into their component parts. Where previous studies have tested single cognitive tasks sequen ...
Full textLink to itemCite
Journal ArticleCirculation · March 8, 2016
BACKGROUND: Swimming-induced pulmonary edema (SIPE) occurs during swimming or scuba diving, often in young individuals with no predisposing conditions, and its pathophysiology is poorly understood. This study tested the hypothesis that pulmonary artery and ...
Full textOpen AccessLink to itemCite
Journal ArticleUndersea Hyperb Med · 2015
A hookah smoker who was treated for severe carbon monoxide poisoning with hyperbaric oxygen reported using a different type of charcoal prior to hospital admission, i.e., quick-light charcoal. This finding led to a study aimed at determining whether CO pro ...
Open AccessLink to itemCite
Journal ArticleHead Neck · December 2014
BACKGROUND: Hyperbaric oxygen (HBO) therapy induces native tissue oxygenation. The hypothesis was patients with mandibular osteoradionecrosis (ORN) and a history of HBO therapy would have less free flap reconstruction complications than patients without HB ...
Full textLink to itemCite
Journal ArticleIntensive Care Med · July 2012
PURPOSE: Necrotising soft tissue infection (NSTI) is a deadly disease associated with a significant risk of mortality and long-term disability from limb and tissue loss. The aim of this study was to determine the effect of hyperbaric oxygen (HBO(2)) therap ...
Full textLink to itemCite
Journal ArticleJ Oral Maxillofac Surg · July 2012
PURPOSE: This study tested hyperbaric oxygen (HBO) as an adjunct to surgery and antibiotics in the treatment of bisphosphonate-related osteonecrosis of the jaw (ONJ) and evaluated its effects on gingival healing, pain, and quality of life. MATERIALS AND ME ...
Full textLink to itemCite
Journal ArticleUndersea Hyperb Med · 2012
INTRODUCTION: Supplemental oxygen has been reported to cause pulmonary complications after bleomycin. We describe the safe administration of hyperbaric oxygen (HBO2) after bleomycin in 15 patients. METHODS: Paper and electronic records were reviewed for bl ...
Link to itemCite
Journal ArticleJ Appl Physiol (1985) · March 2011
Hyperoxia has been shown to attenuate the increase in pulmonary artery (PA) pressure associated with immersed exercise in thermoneutral water, which could serve as a possible preventive strategy for the development of immersion pulmonary edema (IPE). We te ...
Full textLink to itemCite
Journal ArticleJ Appl Physiol (1985) · July 2010
Immersion pulmonary edema (IPE) can occur in otherwise healthy swimmers and divers, likely because of stress failure of pulmonary capillaries secondary to increased pulmonary vascular pressures. Prior studies have revealed progressive increase in ventilati ...
Full textLink to itemCite
Journal ArticleUndersea Hyperb Med · 2010
INTRODUCTION: It is unknown if the benefits of rapid treatment always outweigh the risks of emergency evacuation for recreational divers. To investigate current triage practice, we reviewed a three-year consecutive series of evacuations and analyzed the re ...
Link to itemCite
Journal ArticleInt J Radiat Oncol Biol Phys · November 1, 2009
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PURPOSE: To elucidate long-term outcomes in 65 consecutive patients meeting a uniform definition of mandibular osteoradionecrosis (ORN) treated with multimodality therapy including hyperbaric oxygen (HBO). METHODS AND MATERIALS: Pretreatment, post-treatmen ...
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Journal ArticleJ Oral Maxillofac Surg · May 2009
Featured Publication
Bisphosphonates suppress bone turnover by disrupting osteoclast signal transduction, maturation, and longevity. In some patients, it has been hypothesized that suppressed turnover can impair oral wound healing, leading to a distressing, osteopetrosis-like ...
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Journal ArticleAviat Space Environ Med · May 2009
Featured Publication
omegaWe review the terminology of decompression illness (DCI), investigations of residual symptoms of decompression sickness (DCS), and application of survival analysis for investigating DCI severity and resolution. The Type 1 and Type 2 DCS classification ...
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Journal ArticleJ Appl Physiol (1985) · February 2009
Featured Publication
Immersion pulmonary edema (IPE) is a condition with sudden onset in divers and swimmers suspected to be due to pulmonary arterial or venous hypertension induced by exercise in cold water, although it does occur even with adequate thermal protection. We tes ...
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Journal ArticleJ Appl Physiol (1985) · January 2009
Featured Publication
During diving, arterial Pco(2) (Pa(CO(2))) levels can increase and contribute to psychomotor impairment and unconsciousness. This study was designed to investigate the effects of the hypercapnic ventilatory response (HCVR), exercise, inspired Po(2), and ex ...
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Journal ArticleJ Oral Maxillofac Surg · July 2007
Featured Publication
PURPOSE: Bisphosphonate (BP)-associated osteonecrosis of the jaw (ONJ) is an emerging problem with few therapeutic options. Our pilot study of BP-ONJ investigated a possible role for hyperbaric oxygen (HBO(2)) therapy. PATIENTS AND METHODS: A total of 16 p ...
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Journal ArticleUndersea Hyperb Med · 2007
Featured Publication
INTRODUCTION: First aid oxygen (FAO2) has been widely used as an emergency treatment for diving injuries, but there are few studies supporting its efficacy. METHODS: 2,231 sequential diving injury reports collected by the Divers Alert Network (DAN) Injury ...
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Journal ArticleUndersea Hyperb Med · 2007
Featured Publication
Previous trials of flying at 8,000 ft after a single 60 fsw, 55 min no-stop air dive found low decompression sickness (DCS) risk for a 11:00 preflight surface interval (PFSI). Repetitive 60 fsw no-stop dives with 75 and 95 min total bottom times found 16:0 ...
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Journal ArticleBrain Res · February 23, 2006
Featured Publication
The potency of hyperbaric preconditioning (HBO-PC) is uncertain compared to well-validated ischemic or hypoxic models and no studies have directly compared HBO-PC to hypoxic preconditioning (HPC). We subjected rat pups to unilateral carotid cauterization f ...
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Journal ArticleFree Radic Biol Med · December 1, 2004
Featured Publication
The biochemical paradigm for carbon monoxide (CO) is driven by the century-old Warburg hypothesis: CO alters O(2)-dependent functions by binding heme proteins in competitive relation to 1/oxygen partial pressure (PO(2)). High PO(2) thus hastens CO eliminat ...
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Journal ArticleAviat Space Environ Med · December 2004
Featured Publication
INTRODUCTION: The diagnosis of decompression illness (DCI) is entirely based on clinical findings and DCI experts are rare. Of all the chambers reporting to Diver's Alert Network (DAN), 86% see less than 10 cases per year. Simulated diving injury cases (vi ...
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Journal ArticleUndersea Hyperb Med · 2004
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The brain's anti-oxidant response to highly elevated oxygen (O2) partial pressures is poorly understood. In this study we hypothesized that hyperbaric O2 (HBO2) would stimulate superoxide dismutase (SOD) transcription in the oxidative stress-sensitive rat ...
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Journal ArticleAviat Space Environ Med · October 2002
Featured Publication
BACKGROUND: Decompression sickness (DCS) can be provoked by post-dive flying but few data exist to quantify the risk of different post-dive, preflight surface intervals (PFSI). METHODS: We conducted a case-control study using field data from the Divers Ale ...
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Journal ArticleVaccine · June 7, 2002
Featured Publication
The private demand for a hypothetical vaccine that would provide lifetime protection against HIV/AIDS to an uninfected adult was measured in Guadalajara, Mexico, using the concept of willingness to pay (WTP). A 91-question survey instrument was administere ...
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