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Jorge Valdemar Obando

Associate Professor of Medicine
Medicine, Gastroenterology
Duke Box 3662, Durham, NC 27710
0334 Hospital South, Durham, NC 27710

Selected Publications


Endoscopic devices and techniques for the management of gastric varices (with videos).

Journal Article Gastrointest Endosc · October 31, 2024 BACKGROUND AND AIMS: Gastric variceal bleeding occurs less commonly than bleeding from esophageal varices (EVs), although it is associated with higher morbidity and mortality. Bleeding from gastroesophageal varices type 1 (GOV1) is treated like EVs. In con ... Full text Link to item Cite

Pancreas and biliary ablation devices.

Journal Article Gastrointest Endosc · October 10, 2024 Full text Link to item Cite

Submucosal injection fluid and tattoo agents.

Journal Article Gastrointest Endosc · September 10, 2024 BACKGROUND AND AIMS: EMR and endoscopic submucosal dissection (ESD) are minimally invasive endoscopic techniques, developed for the removal of benign and early malignant lesions throughout the GI tract. Submucosal injection of a marking agent can help to i ... Full text Link to item Cite

Summary: Guidewires in GI endoscopy.

Journal Article Gastrointest Endosc · September 5, 2024 Full text Link to item Cite

Summary: personal protective equipment in GI endoscopy.

Journal Article Gastrointest Endosc · October 2023 Full text Link to item Cite

Guidewires in GI endoscopy

Journal Article iGIE · September 1, 2023 Full text Cite

Ampullary Adenocarcinoma, Version 1.2023, NCCN Clinical Practice Guidelines in Oncology.

Journal Article J Natl Compr Canc Netw · July 2023 Ampullary cancers refer to tumors originating from the ampulla of Vater (the ampulla, the intraduodenal portion of the bile duct, and the intraduodenal portion of the pancreatic duct), while periampullary cancers may arise from locations encompassing the h ... Full text Link to item Cite

Biliary and pancreatic stents.

Journal Article Gastrointest Endosc · June 2023 Full text Link to item Cite

Personal protective equipment in GI endoscopy

Journal Article iGIE · June 1, 2023 Full text Cite

Endoscopic therapies for walled-off necrosis

Journal Article iGIE · June 1, 2023 Background and Aims: Management of walled-off necrosis (WON) has focused on a step-up approach using minimally invasive drainage and debridement techniques. This document reviews the technical aspects of endoscopic management of WON, technical and clinical ... Full text Cite

Biliary and pancreatic stents

Journal Article iGIE · June 1, 2023 Full text Cite

EUS-Directed Transgastric ERCP (EDGE Procedure) for Management of Choledocholithiasis in Post-Gastric Bypass Anatomy

Chapter · January 1, 2023 The current management of biliary pancreatitis or choledocholithiasis consists of prompt decompression of the common bile duct. However, the Roux-en-Y gastric bypass anatomy poses a challenge for retrograde cholangiopancreatography (ERCP) due to the divide ... Full text Cite

Pancreatic Adenocarcinoma, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.

Journal Article J Natl Compr Canc Netw · April 1, 2021 Pancreatic cancer is the fourth leading cause of cancer-related death among men and women in the United States. A major challenge in treatment remains patients' advanced disease at diagnosis. The NCCN Guidelines for Pancreatic Adenocarcinoma provides recom ... Full text Link to item Cite

Pancreatic Adenocarcinoma, Version 1.2019.

Journal Article J Natl Compr Canc Netw · March 1, 2019 The NCCN Guidelines for Pancreatic Adenocarcinoma discuss the diagnosis and management of adenocarcinomas of the exocrine pancreas and are intended to assist with clinical decision-making. These NCCN Guidelines Insights discuss important updates to the 201 ... Full text Link to item Cite

Pancreatic Adenocarcinoma, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology.

Journal Article J Natl Compr Canc Netw · August 2017 Ductal adenocarcinoma and its variants account for most pancreatic malignancies. High-quality multiphase imaging can help to preoperatively distinguish between patients eligible for resection with curative intent and those with unresectable disease. System ... Full text Link to item Cite

Therapeutic Endoscopic Ultrasound.

Journal Article Gastroenterol Hepatol (N Y) · July 2015 Endoscopic ultrasound (EUS) technology has evolved dramatically over the past 20 years, from being a supplementary diagnostic aid available only in large medical centers to being a core diagnostic and therapeutic tool that is widely available. Although for ... Link to item Cite

Pancreatic adenocarcinoma, version 2.2014: featured updates to the NCCN guidelines.

Journal Article J Natl Compr Canc Netw · August 2014 The NCCN Guidelines for Pancreatic Adenocarcinoma discuss the diagnosis and management of adenocarcinomas of the exocrine pancreas and are intended to assist with clinical decision-making. These NCCN Guidelines Insights summarize major discussion points fr ... Full text Link to item Cite

Pancreatitis Secondary to Celiac Trunk Dissection.

Journal Article ACG case reports journal · January 2014 Dissection of the visceral arteries happens infrequently, with the superior mesenteric artery being the most commonly affected. Isolated dissection of the celiac trunk is rare, and only a few cases have been reported in the medical literature. We report th ... Full text Cite

Endoscopic ultrasound: common challenging scenarios.

Journal Article Gastroenterol Hepatol (N Y) · December 2013 Link to item Cite

Pilot study of aprepitant for prevention of post-ERCP pancreatitis in high risk patients: a phase II randomized, double-blind placebo controlled trial.

Journal Article JOP · September 10, 2012 CONTEXT: Animal studies have demonstrated a role for substance P binding to neurokinin-1 receptor in the pathogenesis of acute pancreatitis. OBJECTIVE: Our aim was to assess the efficacy of a neurokinin-1 receptor antagonist (aprepitant) at preventing post ... Full text Link to item Cite

Pancreatic Adenocarcinoma, version 2.2012: featured updates to the NCCN Guidelines.

Journal Article J Natl Compr Canc Netw · June 1, 2012 The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Pancreatic Adenocarcinoma discuss the workup and management of tumors of the exocrine pancreas. These NCCN Guidelines Insights provide a summary and explanation of major changes to the ... Full text Link to item Cite

Endoscopic management of peri-pancreatic collections

Journal Article Gastroenterology Research and Practice · March 21, 2012 Endotherapy of peripancreatic fluid collections is an increasing utilized procedure in interventional endoscopy. The aim of this paper is to provide a general overview of the topic, highlighting the indications, technique, and important management issues r ... Full text Cite

Endoscopic ultrasound-guided fine needle aspiration biopsy of the intrapancreatic accessory spleen: a report of 2 cases.

Journal Article Acta Cytol · 2010 BACKGROUND: Intrapancreatic accessory spleen (IPAS) can pose a challenge in the diagnostic workup by mimicking a pancreatic neoplasm. Reports of IPAS identified by endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) are scant in the literature, ... Full text Link to item Cite

A retroperitoneal bronchogenic cyst.

Journal Article Clin Gastroenterol Hepatol · August 2009 Full text Link to item Cite

Review and recent development of angle-resolved low-coherence interferometry for detection of precancerous cells in human esophageal epithelium

Journal Article IEEE Journal on Selected Topics in Quantum Electronics · January 1, 2008 The combination of low-coherence interferometry with angle-resolved light scattering measurements has been shown to be a powerful method for determining the structure of cell nuclei within intact tissue samples. The nuclear morphology data have been used a ... Full text Cite

Endoscopic Management of the Difficult Benign Esophageal Stricture

Journal Article Techniques in Gastrointestinal Endoscopy · April 1, 2007 The incidence of benign esophageal strictures is decreasing, likely due to the widespread use of proton pump inhibitors. Although most strictures respond well to dilation, a minority of them, mostly those of nonpeptic origin, may be difficult to manage. Ch ... Full text Cite

Outcome of endoscopic minor papillotomy in patients with symptomatic pancreas divisum.

Journal Article JOP · May 2004 Featured Publication CONTEXT: Pancreas divisum has been associated with recurrent acute pancreatitis, chronic abdominal pain without elevated pancreatic enzymes, and chronic pancreatitis. Prior studies suggest that endoscopic minor papillotomy benefits certain symptomatic panc ... Link to item Cite

Iron and HFE or TfR1 mutations as comorbid factors for development and progression of chronic hepatitis C.

Journal Article J Hepatol · December 2002 BACKGROUND/AIMS: Recent evidence implicates iron as a comorbid factor for development of non-hemochromatotic liver diseases. Mutations or polymorphisms in the HFE gene or the TfR1 gene may influence the accumulation of iron in the liver or other tissues or ... Full text Link to item Cite

Upper gastrointestinal bleeding of nonvariceal origin in the ICU setting

Journal Article Journal of Intensive Care Medicine · May 1, 2001 Upper gastrointestinal bleeding (UGI) is a common medical emergency in the intensive care unit (ICU). Although it can be caused by a number of gastrointestinal disorders, its management usually follows a few simple management rules. Prior to endoscopy, the ... Full text Cite

6973 Gender difference on adequacy of unsedated flexible sigmoidoscopies.

Journal Article Gastrointestinal Endoscopy · April 2000 Full text Cite

Role of HFE gene mutations in liver diseases other than hereditary hemochromatosis.

Journal Article Curr Gastroenterol Rep · 1999 Featured Publication Heavy iron overload, as occurs in primary and secondary hemochromatosis, may cause fibrosis of parenchymal organs, including the heart, liver, and pancreas, and it is a risk factor for the development of hepatocellular carcinoma. Recent evidence indicates ... Full text Link to item Cite

Porphyria cutanea tarda, hepatitis C, and HFE gene mutations in North America.

Journal Article Hepatology · June 1998 In some, but not all countries, porphyria cutanea tarda (PCT) has been associated with chronic infection with the hepatitis C virus (HCV). Recently, PCT has also been associated with mutations in the HFE gene that are associated with HLA-linked hereditary ... Full text Link to item Cite