John H. Willis | Scholars@Duke

John H. Willis
Professor of Biology

We conduct research on broad issues in evolutionary genetics, and we are currently addressing questions relating to the evolution of adaptation, reproductive isolation, breeding systems, inbreeding depression, and floral traits in natural plant populations. Please see our lab web page for more information.

Current Appointments & Affiliations

Professor of Biology, Biology, Trinity College of Arts & Sciences 2009

Contact Information

3314 French Science Center, Science Drive, Durham, NC 27708
Box 90338, Department Of Biology, Durham, NC 27708-0338
jwillis@duke.edu (919) 660-7340
Willis Lab homepage

Background
Education, Training, & Certifications
- Ph.D., University of Chicago 1991
Duke Appointment History
- Associate Professor of Biology, Biology, Trinity College of Arts & Sciences 2000 - 2008
Research
Selected Grants
- Collaborative Research: Hybrid Seed Inviability and the Evolution of Endosperm Development in Mimulus awarded by National Science Foundation 2016 - 2019
- DISSERTATION RESEARCH: Understanding the Role of Chromosomal Inversions in Life History Divergence and Local Adaptation in Mimulus awarded by National Science Foundation 2015 - 2018
- Collaborative Proposal: The ecological genomic basis of parallel serpentine adaptation in Mimulus awarded by National Science Foundation 2014 - 2018
- DISSERTATION RESEARCH: Genetic Basis of Population Divergence in the Threshold of Environmental Induction of a Floral Po awarded by National Science Foundation 2014 - 2018
- DISSERTATION RESEARCH: Shedding Light on the Complex Relationship Between Circadian Clock Variation and the Trade-off Be awarded by National Science Foundation 2015 - 2017
- DISSERTATION RESEARCH: Genetic Basis and Adaptive Significance of Key Developmental Traits Underlying awarded by National Science Foundation 2014 - 2017
- A Genomic Analysis of Complex Trait Variation in Mimulus awarded by University of Kansas 2012 - 2016
- LiT: Genomic Analysis of Life-history Adaptation awarded by National Science Foundation 2010 - 2014
- DISSERTATION RESEARCH: The Genetics of Adaptation to a Novel Stressful Environment in Mimulus awarded by National Science Foundation 2012 - 2014
- DISSERTATION RESEARCH: The Genetic Basis of Local Adaptation: Serpentine Tolerance in Mimulus guttatus awarded by National Science Foundation 2011 - 2013
- DISSERTATION RESEARCH: The evolution of phenotypic and genomic changes in allotetraploid Mimulus awarded by National Science Foundation 2010 - 2013
- Do Parental Conflict and Genomic Imprinting Cause Hybrid Lethality in Mimulus? awarded by National Institutes of Health 2011 - 2012
- Discovering Genome Evolution in a Model System for Plant Ecological Genomics awarded by National Institutes of Health 2010 - 2012
- Ecological Genomics of Drought Adaptation in Mimulus awarded by National Science Foundation 2007 - 2011
- FIBR: Integrated Ecological and Genomic Analysis of Speciation in Mimulus awarded by National Science Foundation 2003 - 2010
- DISSERTATION RESEARCH: The geographic mode, ecological mechanisms, as well as genetic basis of local adaptation and ecol awarded by National Science Foundation 2007 - 2010
- DISSERTATION RESEARCH: Evolution of Copper Tolerance in Mimulus guttatus awarded by National Science Foundation 2007 - 2010
- DISSERTATION RESEARCH: Genetics and evolutionary ecology of a flower color diversification in Chilean Mimulus awarded by National Science Foundation 2005 - 2008
- DISSERTATION RESEARCH: Identification and characterization of incompatibility genes that contribute to postzygotic repro awarded by National Science Foundation 2004 - 2006
- REU (Supplement): A genome-wide investigation of factors causing postzygotic isolation awarded by National Science Foundation 2003 - 2004
- A genome-wide investigation of factors causing postzygotic isolation between two Mimulus species awarded by National Science Foundation 2000 - 2004
- Dissertation Research: Ecological genetics of life-history evolution in Mimulus guttatus awarded by National Science Foundation 2001 - 2003
- Doctoral Dissertation: Barriers to genetic exchange between two species of Mimulus awarded by National Science Foundation 2000 - 2002
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Selby, JP, and Willis, JH. "Major QTL controls adaptation to serpentine soils in Mimulus guttatus." Molecular Ecology 27, no. 24 (December 18, 2018): 5073-5087. Full Text
  - Toll, K, and Willis, JH. "Hybrid inviability and differential submergence tolerance drive habitat segregation between two congeneric monkeyflowers." Ecology (October 26, 2018). Full Text
  - Troth, A, Puzey, JR, Kim, RS, Willis, JH, and Kelly, JK. "Selective trade-offs maintain alleles underpinning complex trait variation in plants." Science (New York, N.Y.) 361, no. 6401 (August 2018): 475-478. Full Text
  - Coughlan, JM, and Willis, JH. "Dissecting the role of a large chromosomal inversion in life history divergence throughout the Mimulus guttatus species complex." Molecular Ecology (July 20, 2018). Full Text
  - Ferris, KG, and Willis, JH. "Differential adaptation to a harsh granite outcrop habitat between sympatric Mimulus species." Evolution; International Journal of Organic Evolution 72, no. 6 (June 2018): 1225-1241. Full Text
  - Barnett, LL, Troth, A, and Willis, JH. "Plastic breeding system response to day length in the California wildflower Mimulus douglasii." American Journal of Botany 105, no. 4 (April 25, 2018): 779-787. Full Text
  - Aeschbacher, S, Selby, JP, Willis, JH, and Coop, G. "Population-genomic inference of the strength and timing of selection against gene flow." Proceedings of the National Academy of Sciences of the United States of America 114, no. 27 (July 2017): 7061-7066. Full Text
  - Greenham, K, Lou, P, Puzey, JR, Kumar, G, Arnevik, C, Farid, H, Willis, JH, and McClung, CR. "Geographic Variation of Plant Circadian Clock Function in Natural and Agricultural Settings." Journal of Biological Rhythms 32, no. 1 (February 2017): 26-34. Full Text
  - Ferris, KG, Barnett, LL, Blackman, BK, and Willis, JH. "The genetic architecture of local adaptation and reproductive isolation in sympatry within the Mimulus guttatus species complex." Molecular ecology 26, no. 1 (January 2017): 208-224. Full Text
  - Fierst, JL, Murdock, DA, Thanthiriwatte, C, Willis, JH, and Phillips, PC. "Metagenomeassembled draft genome sequence of a novel microbial Stenotrophomonas maltophilia strain isolated from Caenorhabditis remanei tissue." Genome Announcements 5, no. 7 (January 1, 2017). Full Text
  - Puzey, JR, Willis, JH, and Kelly, JK. "Population structure and local selection yield high genomic variation in Mimulus guttatus." Molecular Ecology 26, no. 2 (January 2017): 519-535. Full Text
  - Oneal, E, Willis, JH, and Franks, RG. "Disruption of endosperm development is a major cause of hybrid seed inviability between Mimulus guttatus and Mimulus nudatus." The New Phytologist 210, no. 3 (May 2016): 1107-1120. Full Text
  - Lee, YW, Fishman, L, Kelly, JK, and Willis, JH. "A Segregating Inversion Generates Fitness Variation in Yellow Monkeyflower (Mimulus guttatus)." Genetics 202, no. 4 (April 2016): 1473-1484. Full Text
  - Fierst, JL, Willis, JH, Thomas, CG, Wang, W, Reynolds, RM, Ahearne, TE, Cutter, AD, and Phillips, PC. "Erratum to: Reproductive Mode and the Evolution of Genome Size and Structure in Caenorhabditis Nematodes (PLoS Genet, (2015), 11, 9)." Plos Genetics 11, no. 9 (September 22, 2015). Full Text
  - Ferris, KG, Rushton, T, Greenlee, AB, Toll, K, Blackman, BK, and Willis, JH. "Leaf shape evolution has a similar genetic architecture in three edaphic specialists within the Mimulus guttatus species complex." Annals of Botany 116, no. 2 (August 2015): 213-223. Full Text
  - Fierst, JL, Willis, JH, Thomas, CG, Wang, W, Reynolds, RM, Ahearne, TE, Cutter, AD, and Phillips, PC. "Reproductive Mode and the Evolution of Genome Size and Structure in Caenorhabditis Nematodes." Plos Genetics 11, no. 6 (June 26, 2015): e1005323-null. Full Text
  - Friedman, J, Twyford, AD, Willis, JH, and Blackman, BK. "The extent and genetic basis of phenotypic divergence in life history traits in Mimulus guttatus." Molecular ecology 24, no. 1 (January 2015): 111-122. Full Text
  - Ferris, KG, Sexton, JP, and Willis, JH. "Speciation on a local geographic scale: the evolution of a rare rock outcrop specialist in Mimulus." Philosophical transactions of the Royal Society of London. Series B, Biological sciences 369, no. 1648 (August 2014). Full Text
  - Oneal, E, Lowry, DB, Wright, KM, Zhu, Z, and Willis, JH. "Divergent population structure and climate associations of a chromosomal inversion polymorphism across the Mimulus guttatus species complex." Molecular ecology 23, no. 11 (June 2014): 2844-2860. Full Text
  - Fishman, L, Willis, JH, Wu, CA, and Lee, Y-W. "Comparative linkage maps suggest that fission, not polyploidy, underlies near-doubling of chromosome number within monkeyflowers (Mimulus; Phrymaceae)." Heredity (Edinb) 112, no. 5 (May 2014): 562-568. Full Text Link to Item
  - Fishman, L, Willis, JH, Wu, CA, and Lee, YW. "Comparative linkage maps suggest that fission, not polyploidy, underlies near-doubling of chromosome number within monkeyflowers (Mimulus; Phrymaceae)." Heredity 112, no. 5 (January 1, 2014): 562-568. Full Text
  - Flagel, LE, Willis, JH, and Vision, TJ. "The standing pool of genomic structural variation in a natural population of Mimulus guttatus." Genome Biology and Evolution 6, no. 1 (January 2014): 53-64. Full Text
  - Hellsten, U, Wright, KM, Jenkins, J, Shu, S, Yuan, Y, Wessler, SR, Schmutz, J, Willis, JH, and Rokhsar, DS. "Fine-scale variation in meiotic recombination in Mimulus inferred from population shotgun sequencing." Proceedings of the National Academy of Sciences of the United States of America 110, no. 48 (November 13, 2013): 19478-19482. Full Text
  - Friedman, J, and Willis, JH. "Major QTLs for critical photoperiod and vernalization underlie extensive variation in flowering in the Mimulus guttatus species complex." The New Phytologist 199, no. 2 (July 2013): 571-583. Full Text
  - Friedman, J, and Willis, JH. "Major QTLs for critical photoperiod and vernalization underlie extensive variation in flowering in the Mimulus guttatus species complex." New Phytologist 199, no. 2 (2013): 571-583. Full Text
  - Wright, KM, Lloyd, D, Lowry, DB, Macnair, MR, and Willis, JH. "Indirect evolution of hybrid lethality due to linkage with selected locus in Mimulus guttatus." Plos Biology 11, no. 2 (January 2013): e1001497-null. Full Text
  - Sweigart, AL, and Willis, JH. "Molecular evolution and genetics of postzygotic reproductive isolation in plants." F1000 Biology Reports 4, no. 1 (December 3, 2012). Full Text
  - Modliszewski, JL, and Willis, JH. "Allotetraploid Mimulus sookensis are highly interfertile despite independent origins." Molecular Ecology 21, no. 21 (November 2012): 5280-5298. Full Text
  - Mojica, JP, Lee, YW, Willis, JH, and Kelly, JK. "Spatially and temporally varying selection on intrapopulation quantitative trait loci for a life history trade-off in Mimulus guttatus." Molecular Ecology 21, no. 15 (August 2012): 3718-3728. Full Text
  - Strasburg, JL, Sherman, NA, Wright, KM, Moyle, LC, Willis, JH, and Rieseberg, LH. "What can patterns of differentiation across plant genomes tell us about adaptation and speciation?." Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 367, no. 1587 (February 2012): 364-373. (Review) Full Text
  - Benedict, BG, Modliszewski, JL, Sweigart, AL, Martin, NH, Ganders, FR, and Willis, JH. "Mimulus sookensis (Phyrmaceae), a new allotetraploid species derived from Mimulus guttatus and Mimulus nasutus." Madrono 59 (2012): 29-43. (Academic Article)
  - Lowry, DB, Sheng, CC, Lasky, JR, and Willis, JH. "Five anthocyanin polymorphisms are associated with an R2R3-MYB cluster in Mimulus guttatus (Phrymaceae)." Am J Bot 99, no. 1 (January 2012): 82-91. Full Text Link to Item
  - Lowry, DB, Sheng, CC, Zhu, Z, Juenger, TE, Lahner, B, Salt, DE, and Willis, JH. "Mapping of ionomic traits in Mimulus guttatus reveals Mo and Cd QTLs that colocalize with MOT1 homologues." PLoS One 7, no. 1 (2012): e30730-. Full Text Link to Item
  - Modliszewski, JL, and Willis, JH. "Near-Absent Levels Of Segregational Variation Suggest Limited Opportunities For The introduction of genetic variation via homeologous chromosome pairing In synthetic neoallotetraploid Mimulus. (Submitted)" Genetics (2012). (Academic Article)
  - Moran, EV, Willis, J, and Clark, JS. "Genetic evidence for hybridization in red oaks (Quercus sect. Lobatae, Fagaceae)." American Journal of Botany 99, no. 1 (January 2012): 92-100. Full Text
  - Mower, JP, Case, AL, Floro, ER, and Willis, JH. "Evidence against equimolarity of large repeat arrangements and a predominant master circle structure of the mitochondrial genome from a monkeyflower (Mimulus guttatus) lineage with cryptic CMS." Genome Biology and Evolution 4, no. 5 (2012): 670-686. Full Text
  - Magwene, PM, Willis, JH, and Kelly, JK. "The statistics of bulk segregant analysis using next generation sequencing." Plos Comput Biol 7, no. 11 (November 2011): e1002255-null. Full Text Link to Item
  - Anderson, JT, Willis, JH, and Mitchell-Olds, T. "Evolutionary genetics of plant adaptation." Trends in Genetics : Tig 27, no. 7 (July 2011): 258-266. (Review) Full Text
  - Cooley, AM, Modliszewski, JL, Rommel, ML, and Willis, JH. "Gene duplication in Mimulus underlies parallel floral evolution via independent trans-regulatory changes." Current Biology : Cb 21, no. 8 (April 7, 2011): 700-704. Full Text
  - Scoville, AG, Lee, YW, Willis, JH, and Kelly, JK. "Explaining the heritability of an ecologically significant trait in terms of individual quantitative trait loci." Biology Letters 7, no. 6 (2011): 896-898. Full Text
  - Willis, JH, Fishman, L, and Sweigart, A. "The ecology and genetics of Mimulus." Annual Review of Ecology, Evolution, and Systematics 42 (January 1, 2011). Full Text
  - Martin, NH, and Willis, JH. "Erratum: Geographical variation in postzygotic isolation and its genetic basis within and between two Mimulus species (Philosophical Transactions of the Royal Society B: Biological Sciences (2010) 365 (2469-2478) DOI: 10.1098/rstb.2010.0030)." Philosophical Transactions of the Royal Society B: Biological Sciences 365, no. 1555 (October 12, 2010): 3261-null. Full Text
  - Lowry, DB, and Willis, JH. "A widespread chromosomal inversion polymorphism contributes to a major life-history transition, local adaptation, and reproductive isolation." Plos Biology 8, no. 9 (September 28, 2010). Full Text Open Access Copy
  - Martin, NH, and Willis, JH. "Geographical variation in postzygotic isolation and its genetic basis within and between two Mimulus species." Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 365, no. 1552 (August 2010): 2469-2478. Full Text
  - Hall, MC, Lowry, DB, and Willis, JH. "Is local adaptation in Mimulus guttatus caused by trade-offs at individual loci?." Molecular Ecology 19, no. 13 (2010): 2739-2753. Full Text
  - Wu, CA, Lowry, DB, Nutter, LI, and Willis, JH. "Natural variation for drought-response traits in the Mimulus guttatus species complex." Oecologia 162, no. 1 (January 2010): 23-33. Full Text
  - Charlesworth, D, and Willis, JH. "The genetics of inbreeding depression." Nature Reviews. Genetics 10, no. 11 (November 2009): 783-796. (Review) Full Text
  - Cooley, AM, and Willis, JH. "Genetic divergence causes parallel evolution of flower color in Chilean Mimulus." The New Phytologist 183, no. 3 (August 2009): 729-739. Full Text
  - Lowry, DB, Hall, MC, Salt, DE, and Willis, JH. "Genetic and physiological basis of adaptive salt tolerance divergence between coastal and inland Mimulus guttatus." The New Phytologist 183, no. 3 (August 2009): 776-788. Full Text
  - Willis, JH. "Genetics. Origin of species in overdrive." Science 323, no. 5912 (January 16, 2009): 350-351. Full Text Link to Item
  - Scoville, A, Lee, YW, Willis, JH, and Kelly, JK. "Contribution of chromosomal polymorphisms to the G-matrix of Mimulus guttatus." New Phytologist 183, no. 3 (2009): 803-815. Full Text
  - Willis, JH. "Origin of species in overdrive." Science 323 (2009): 350-351. (Academic Article)
  - Lowry, DB, Modliszewski, JL, Wright, KM, Wu, CA, and Willis, JH. "Review. The strength and genetic basis of reproductive isolating barriers in flowering plants." Philos Trans R Soc Lond B Biol Sci 363, no. 1506 (September 27, 2008): 3009-3021. (Review) Full Text Link to Item
  - Lowry, DB, Modliszewski, JL, Wright, KM, Wu, CA, and Willis, JH. "Review. The strength and genetic basis of reproductive isolating barriers in flowering plants." Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 363, no. 1506 (September 2008): 3009-3021. (Review) Full Text
  - Lowry, DB, Rockwood, RC, and Willis, JH. "Ecological reproductive isolation of coast and inland races of Mimulus guttatus." Evolution; International Journal of Organic Evolution 62, no. 9 (September 2008): 2196-2214. Full Text
  - McDaniel, SF, Willis, JH, and Shaw, AJ. "The genetic basis of developmental abnormalities in interpopulation hybrids of the moss Ceratodon purpureus." Genetics 179, no. 3 (July 2008): 1425-1435. Full Text
  - Case, AL, and Willis, JH. "Hybrid male sterility in Mimulus (Phrymaceae) is associated with a geographically restricted mitochondrial rearrangement." Evolution; International Journal of Organic Evolution 62, no. 5 (May 2008): 1026-1039. Full Text
  - Cooley, AM, Carvallo, G, and Willis, JH. "Is floral diversification associated with pollinator divergence? Flower shape, flower colour and pollinator preference in Chilean Mimulus." Annals of Botany 101, no. 5 (April 2008): 641-650. Full Text
  - Wu, CA, Lowry, DB, Cooley, AM, Wright, KM, Lee, YW, and Willis, JH. "Mimulus is an emerging model system for the integration of ecological and genomic studies." Heredity (Edinb) 100, no. 2 (February 2008): 220-230. (Review) Full Text Link to Item
  - Fishman, L, and Willis, JH. "Pollen limitation and natural selection on floral characters in the yellow monkeyflower, Mimulus guttatus." The New Phytologist 177, no. 3 (January 2008): 802-810. Full Text
  - Sweigart, AL, Martin, NH, and Willis, JH. "Patterns of nucleotide variation and reproductive isolation between a Mimulus allotetraploid and its progenitor species." Molecular Ecology 17, no. 8 (2008): 2089-2100. Full Text
  - Mitchell-Olds, T, Willis, JH, and Goldstein, DB. "Which evolutionary processes influence natural genetic variation for phenotypic traits?." Nature Reviews. Genetics 8, no. 11 (November 2007): 845-856. (Review) Full Text
  - McDaniel, SF, Willis, JH, and Shaw, AJ. "A linkage map reveals a complex basis for segregation distortion in an interpopulation cross in the moss Ceratodon purpureus." Genetics 176, no. 4 (August 2007): 2489-2500. Full Text
  - Rieseberg, LH, and Willis, JH. "Plant speciation." Science (New York, N.Y.) 317, no. 5840 (August 2007): 910-914. (Review) Full Text
  - Martin, NH, and Willis, JH. "Ecological divergence associated with mating system causes nearly complete reproductive isolation between sympatric Mimulus species." Evolution; International Journal of Organic Evolution 61, no. 1 (January 2007): 68-82. Full Text
  - Mitchell Olds, T, Willis, JH, and Goldstein, D. "What evolutionary processes influence natural genetic variation for phenotypic traits?." Nature Reviews Genetics 8 (2007): 845-856. (Academic Article)
  - Sweigart, AL, Mason, AR, and Willis, JH. "Natural variation for a hybrid incompatibility between two species of Mimulus." Evolution; International Journal of Organic Evolution 61, no. 1 (January 2007): 141-151. Full Text
  - Hall, MC, and Willis, JH. "Divergent selection on flowering time contributes to local adaptation in Mimulus guttatus populations." Evolution; International Journal of Organic Evolution 60, no. 12 (December 2006): 2466-2477. Full Text
  - Aagaard, JE, Willis, JH, and Phillips, PC. "Relaxed selection among duplicate floral regulatory genes in Lamiales." Journal of Molecular Evolution 63, no. 4 (October 4, 2006): 493-503. Full Text
  - Sweigart, AL, Fishman, L, and Willis, JH. "A simple genetic incompatibility causes hybrid male sterility in mimulus." Genetics 172, no. 4 (April 2006): 2465-2479. Full Text Link to Item
  - Hall, MC, Basten, CJ, and Willis, JH. "Pleiotropic quantitative trait loci contribute to population divergence in traits associated with life-history variation in Mimulus guttatus." Genetics 172, no. 3 (March 2006): 1829-1844. Full Text
  - Fishman, L, and Willis, JH. "A cytonuclear incompatibility causes anther sterility in Mimulus hybrids." Evolution 60, no. 7 (2006): 1372-1381. Full Text
  - Hall, MC, and Willis, JH. "Transmission ratio distortion in intraspecific hybrids of Mimulus guttatus: implications for genomic divergence." Genetics 170, no. 1 (May 2005): 375-386. Full Text Link to Item
  - Aagaard, JE, Olmstead, RG, Willis, JH, and Phillips, PC. "Duplication of floral regulatory genes in the Lamiales." American Journal of Botany 92, no. 8 (2005): 1284-1293. Full Text
  - Fishman, L, and Willis, JH. "A novel meiotic drive locus almost completely distorts segregation in mimulus (monkeyflower) hybrids." Genetics 169, no. 1 (January 2005): 347-353. Full Text
  - Sweigart, AL, and Willis, JH. "Patterns of nucleotide diversity are affected by mating system and asymmetric introgression in two species of Mimulus." Evolution 57 (November 2003): 2490-2506. (Academic Article)
  - Sweigart, AL, and Willis, JH. "Patterns of nucleotide diversity in two species of Mimulus are affected by mating system and asymmetric introgression." Evolution 57, no. 11 (November 2003): 2490-2506. Link to Item
  - Fishman, L, Kelly, AJ, and Willis, JH. "Minor quantitative trait loci underlie floral traits associated with mating system divergence in Mimulus." Evolution; International Journal of Organic Evolution 56, no. 11 (November 2002): 2138-2155. Full Text
  - Fishman, L, Kelly, AJ, and Willis, JH. "Minor QTLs underlie floral characters associated with mating system divergence in Mimulus." Evolution 56 (2002): 2138-2155. (Academic Article)
  - Kelly, JK, and Willis, JH. "A manipulative experiment to estimate biparental inbreeding in monkeyflowers." International Journal of Plant Sciences 163, no. 4 (January 1, 2002): 575-579. Full Text
  - Fishman, L, Kelly, AJ, Morgan, E, and Willis, JH. "A genetic map in the Mimulus guttatus species complex reveals transmission ratio distortion due to heterospecific interactions." Genetics 159, no. 4 (December 2001): 1701-1716. Link to Item
  - Fishman, L, and Willis, JH. "Evidence for Dobzhansky-Muller incompatibilites contributing to the sterility of hybrids between Mimulus guttatus and M. nasutus." Evolution 55, no. 10 (October 2001): 1932-1942. Link to Item
  - Kelly, JK, and Willis, JH. "Deleterious mutations and genetic variation for flower size in Mimulus guttatus." Evolution 55, no. 5 (2001): 937-942.
  - Willis, JH. "The role of genes of large effect on inbreeding depression in Mimulus guttatus." Evolution 53, no. 6 (December 1, 1999): 1678-1691.
  - Willis, JH. "Inbreeding load, average dominance and the mutation rate for mildly deleterious alleles in Mimulus guttatus." Genetics 153, no. 4 (December 1999): 1885-1898.
  - Lynch, M, Blanchard, J, Houle, D, Kibota, T, Schultz, S, Vassilieva, L, and Willis, J. "Perspective: Spontaneous deleterious mutation." Evolution 53, no. 3 (June 1, 1999): 645-663.
  - Lynch, M, Blanchard, J, Houle, D, Kibota, T, Schultz, S, Vassilieva, L, and Willis, JH. "Spontaneous deleterious mutation." Evolution 53 (1999): 645-663. (Academic Article)
  - Schultz, ST, Lynch, M, and Willis, JH. "The genomic mutation rate for fitness in Arabidopsis thaliana." Procedings of the National Academy of Science, USA 96 (1999): 11393-11398. (Academic Article)
  - Schultz, ST, Lynch, M, and Willis, JH. "Spontaneous deleterious mutation in Arabidopsis thaliana." Proceedings of the National Academy of Sciences of the United States of America 96, no. 20 (1999): 11393-11398. Full Text
  - Sweigart, A, Karoly, K, Jones, A, and Willis, JH. "The distribution of individual inbreeding coefficients and pairwise relatedness in a population of Mimulus guttatus." Heredity 83, no. 5 (January 1, 1999): 625-632. Full Text
  - Willis, JH. "The contribution of male-sterility mutations to inbreeding depression in Mimulus guttatus." Heredity 83, no. 3 (1999): 337-346.
  - Kelly, AJ, and Willis, JH. "Polymorphic microsatellite loci in Mimulus guttatus and related species." Molecular Ecology 7, no. 6 (January 1, 1998): 769-774. Full Text
  - Willis, JH. "Measures of phenotypic selection are biased by partial inbreeding." Evolution 50, no. 4 (August 1, 1996): 1501-1511.
  - Schultz, ST, and Willis, JH. "Individual variation in inbreeding depression: the roles of inbreeding history and mutation." Genetics 141, no. 3 (November 1995): 1209-1223.
  - Gimelfarb, A, and Willis, JH. "Linearity Versus nonlinearity of offspring-parent regression: an experimental study of Drosophila melanogaster." Genetics 138, no. 2 (October 1994): 343-352.
  - Gimelfarb, A, and Willis, JH. "Linearity vs. nonlinearity of offspring-parent regression: experimental study." Genetics 138 (1994): 343-352. (Academic Article)
  - Willis, JH, and Orr, HA. "Increased heritable variation following population bottlenecks: The role of dominance." Evolution 47 (1993): 949-957. (Academic Article)
  - Willis, JH. "Effects of different levels of inbreeding on fitness components in Mimulus guttatus." Evolution 47, no. 3 (January 1, 1993): 864-876.
  - Willis, JH. "Partial self-fertilization and inbreeding depression in two populations of mimulus guttatus." Heredity 71, no. 2 (January 1, 1993): 145-154. Full Text
  - Willis, JH. "Genetic analysis of inbreeding depression caused by chlorophyll-deficient lethals in mimulus guttatus." Heredity 69, no. 6 (January 1, 1992): 562-572. Full Text
  - Willis, JH, Coyne, JA, and Kirkpatrick, M. "Can one predict the evolution of quantitative traits without genetics?." Evolution 45 (1991): 441-444. (Academic Article)
  - Bergelson, JM, Willis, JH, and Robakiewicz, PE. "Variance in search time: Do groups always reduce risk?." Animal Behaviour 34, no. PART 1 (January 1, 1986): 289-291. Full Text
Teaching & Mentoring
Recent Courses
Scholarly, Clinical, & Service Activities
Presentations & Appearances
Service to the Profession
- Panel Member, Organism-Environment Interactions Program, Division of Integrated Organismal Systems, National Science Foundation. October 13, 2010 2010

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Education, Training, & Certifications

Duke Appointment History

Selected Grants

Selected Publications

Academic Articles

Recent Courses

Presentations & Appearances

Service to the Profession