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Herbert Kim Lyerly

George Barth Geller Distinguished Professor of Immunology
Surgery, Surgical Sciences
Box 2606 Med Ctr, Durham, NC 27710
203 Research Drive, Rm 433B, Box 2606, Durham, NC 27710

Current Appointments & Affiliations


George Barth Geller Distinguished Professor of Immunology · 2004 - Present Surgery, Surgical Sciences, Surgery
Professor of Surgery · 2011 - Present Surgery, Surgical Sciences, Surgery
Professor in Integrative Immunobiology · 2017 - Present Integrative Immunobiology, Basic Science Departments
Professor of Pathology · 2018 - Present Pathology, Clinical Science Departments
Member of the Duke Cancer Institute · 1983 - Present Duke Cancer Institute, Institutes and Centers
Affiliate, Duke Global Health Institute · 2014 - Present Duke Global Health Institute, University Institutes and Centers
Affiliate of the Duke Regeneration Center · 2021 - Present Duke Regeneration Center, Basic Science Departments
Core Faculty Member, Duke-Margolis Institute for Health Policy · 2024 - Present Duke-Margolis Institute for Health Policy, University Institutes and Centers

In the News


Published July 13, 2021
Higher Rates of Alzheimer’s Deaths, Hospitalizations Correlate with Air Pollution
Published April 20, 2020
BRIEF-OncoSec Appoints Oncologist And Immunologist Herbert Kim Lyerly To Board Of Directors
Published December 2, 2019
Innovative Model Allows Researchers to Watch Cancer Cells Spread in Colon Before Cancer Is Even Detected

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Recent Publications


CD27 agonism enhances long-lived CD4 T cell vaccine responses critical for antitumor immunity.

Journal Article Sci Immunol · December 19, 2025 Tumor antigen vaccination represents an appealing approach for cancer but has failed to materialize as oncologic standard of care. To understand long-term vaccine efficacy, we conducted a retrospective analysis of patients with human epidermal growth recep ... Full text Link to item Cite
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Recent Grants


Duke University Program in Environmental Health

Inst. Training Prgm or CMEMentor · Awarded by National Institute of Environmental Health Sciences · 2019 - 2029

Single Cell and Spatial Analysis of Lethal Breast Cancers

ResearchPrincipal Investigator · Awarded by Department of Defense · 2024 - 2028

The paradox of obesity, tumor progression, and checkpoint inhibition in TNBC

ResearchMentor · Awarded by Susan G Komen for the Cure · 2023 - 2026

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Education, Training & Certifications


University of California, Los Angeles · 1983 M.D.