Scholars@Duke
Maria J. Marquine

Maria J. Marquine

Associate Professor in Medicine
Medicine, Geriatrics and Palliative Care
maria.marquine@duke.edu
Box 3003 Med Ctr, Durham, NC 27710
40 Duke Medicine Circle, Duke Aging Center, Durham, NC 27710

Selected Publications

Spanish Translation and Cultural Adaptation of the Intensive Care Unit Delirium Playbook

Journal Article ATS Scholar · June 1, 2024 Background: A lack of high-quality provider education hinders the delivery of standard-of-care delirium detection and prevention practices in the intensive care unit (ICU). To fill this gap, we developed and validated an e-learning ICU Delirium Playbook co ... Full text Cite

Disparities in Metabolic Syndrome and Neurocognitive Function Among Older Hispanics/Latinos with Human Immunodeficiency Virus.

Journal Article AIDS Patient Care STDS · May 2024 Neurocognitive impairment and metabolic syndrome (MetS) are prevalent in persons with HIV (PWH). We examined disparities in HIV-associated neurocognitive function between Hispanic and non-Hispanic White older PWH, and the role of MetS in explaining these d ... Full text Link to item Cite

Differences in metabolic biomarkers in people with schizophrenia who are of Mexican descent compared to non-Hispanic whites.

Journal Article Psychiatry Res · April 2024 Metabolic dysfunction is highly prevalent and contributes to premature mortality among people with schizophrenia (PwS), especially in Hispanic/Latino/a/x/e PwS, compared to non-Hispanic White (NHW) PwS. This study evaluated the relative contributions of Me ... Full text Link to item Cite

Emotional health and its association with neurocognition in Hispanic and non-Hispanic White people with HIV.

Journal Article J Int Neuropsychol Soc · January 2024 OBJECTIVE: Emotional functioning is linked to HIV-associated neurocognitive impairment, yet research on this association among diverse people with HIV (PWH) is scant. We examined emotional health and its association with neurocognition in Hispanic and Whit ... Full text Link to item Cite

Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management.

Journal Article Nat Rev Neurol · November 2023 People living with HIV are affected by the chronic consequences of neurocognitive impairment (NCI) despite antiretroviral therapies that suppress viral replication, improve health and extend life. Furthermore, viral suppression does not eliminate the virus ... Full text Link to item Cite

B - 45 Differences in the Association between Social Activity and Neurocognition between Latino and Non-Hispanic White Older Adults with HIV

Journal Article Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · October 20, 2023 OBJECTIVE: Older Hispanics/Latinos/as/x (henceforth Latinos) are disproportionately affected by HIV-associated neurocognitive impairment compared to their non-Hispanic White counterparts. We examined social activity as a possible protective factor against ... Full text Cite

Demographically-adjusted normative data among Latinos for the version 3 of the Alzheimer's Disease Centers' Neuropsychological Test Battery in the Uniform Data Set.

Journal Article Alzheimers Dement · September 2023 INTRODUCTION: We developed demographically-adjusted normative data for Spanish- and English-speaking Latinos on the Version 3.0 of the National Alzheimer's Coordinating Center Uniform Data Set Neuropsychological Battery (UDS3-NB). METHODS: Healthy Latino a ... Full text Link to item Cite

An Examination of Racial/Ethnic Differences on the Neurobehavioral Symptom Inventory Among Veterans Completing the Comprehensive Traumatic Brain Injury Evaluation: A Veterans Affairs Million Veteran Program Study.

Journal Article Arch Clin Neuropsychol · August 24, 2023 OBJECTIVE: The purpose of this study was to explore racial/ethnic differences in neurobehavioral symptom reporting and symptom validity testing among military veterans with a history of traumatic brain injury (TBI). METHOD: Participants of this observation ... Full text Link to item Cite

Association Between VACS Index and Health-Related Quality of Life in Persons with HIV: Moderating Role of Fruit and Vegetable Consumption.

Journal Article Int J Behav Med · June 2023 BACKGROUND: The health status of people with HIV (PWH) influences their health-related quality of life (HRQOL). Modifiable lifestyle factors may improve HRQOL. This study (1) explores the association between modifiable lifestyle factors (physical activity ... Full text Link to item Cite

Cognitive Impairment After Ischemic and Hemorrhagic Stroke: A Scientific Statement From the American Heart Association/American Stroke Association.

Journal Article Stroke · June 2023 PURPOSE: Cognitive impairment is a common consequence of stroke and has direct implications for poststroke functioning and quality of life, including the ability to maintain a job, live independently, sustain interpersonal relationships, and drive a vehicl ... Full text Link to item Cite

Concurrent validity and reliability of at-home teleneuropsychological evaluations among people with and without HIV.

Journal Article J Int Neuropsychol Soc · February 2023 OBJECTIVE: To determine the reliability of teleneuropsychological (TNP) compared to in-person assessments (IPA) in people with HIV (PWH) and without HIV (HIV-). METHODS: Participants included 80 PWH (Mage = 58.7, SDage = 11.0) and 23 HIV- (Mage = 61.9, SDa ... Full text Link to item Cite

High Psychosocial Burden Relates to Poorer Antiretroviral Treatment Adherence Among Black/African American People with HIV.

Journal Article AIDS Patient Care STDS · February 2023 Black/African American communities continue to be disproportionately impacted by HIV with Black people with HIV (PWH) exhibiting poorer outcomes along the HIV treatment cascade. Psychosocial burden may, in part, explain these health disparities among PWH. ... Full text Link to item Cite

Migration and Cognitive Health Disparities: The Arab American and Refugee Case.

Journal Article J Gerontol B Psychol Sci Soc Sci · January 28, 2023 OBJECTIVES: This study investigates whether the year of arrival to the United States (U.S.) and birthplace relate to postmigration cognitive difficulties among foreign- and U.S.-born Arab Americans in later life. METHODS: We analyzed 19 years (2000-2019) o ... Full text Link to item Cite

NIH Toolbox Emotion Battery Findings Among People with HIV: Normative Comparisons and Clinical Associations.

Journal Article Patient Relat Outcome Meas · 2023 PURPOSE: Depression and other aspects of emotional health in people with HIV (PWH) can affect functional independence, disease progression, and overall life quality. This study used the NIH Toolbox Emotion Battery (NIHTB-EB), which assesses many features o ... Full text Link to item Cite

Influence of Educational Background, Childhood Socioeconomic Environment, and Language Use on Cognition among Spanish-Speaking Latinos Living Near the US-Mexico Border.

Journal Article J Int Neuropsychol Soc · September 2022 OBJECTIVES: We investigated the impact of culturally relevant social, educational, and language factors on cognitive test performance among Spanish speakers living near the US-Mexico border. METHODS: Participants included 254 healthy native Spanish speaker ... Full text Link to item Cite

Higher religiosity and spirituality are associated with ethnic group membership among middle-aged and older adults living with HIV.

Journal Article HIV Res Clin Pract · August 16, 2022 Background: HIV is a chronic illness that impacts the lives of more than 1 million people in the United States. As persons living with HIV (PWH) are living longer, it is important to understand the influence that religiosity/spirituality has among middle-a ... Link to item Cite

The association between benzodiazepine use and greater risk of neurocognitive impairment is moderated by medical burden in people with HIV.

Journal Article J Neurovirol · June 2022 Benzodiazepine use is linked to neurocognitive impairment (NCI) in the general population and people with HIV (PWH); however, this relationship may depend on age-related factors such as medical comorbidities, which occur at an elevated rate and manifest ea ... Full text Link to item Cite

The Association of Stress, Metabolic Syndrome, and Systemic Inflammation With Neurocognitive Function in the Hispanic Community Health Study/Study of Latinos and Its Sociocultural Ancillary Study.

Journal Article J Gerontol B Psychol Sci Soc Sci · May 5, 2022 OBJECTIVES: Identifying sociocultural correlates of neurocognitive dysfunction among Hispanics/Latinos, and their underlying biological pathways, is crucial for understanding disparities in Alzheimer's disease and related dementias. We examined cross-secti ... Full text Link to item Cite

Ethnic/Racial Disparities in Longitudinal Neurocognitive Decline in People With HIV.

Journal Article J Acquir Immune Defic Syndr · May 1, 2022 BACKGROUND: To examine longitudinal neurocognitive decline among Latino, non-Latino Black, and non-Latino White people with HIV (PWH) and factors that may explain ethnic/racial disparities in neurocognitive decline. METHODS: Four hundred ninety nine PWH (1 ... Full text Link to item Cite

Concordance Between Self-Reported Medical Diagnosis of Mild Cognitive Impairment/Dementia and Neurocognitive Function Among Middle-Aged and Older Hispanic/Latino Adults: Results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) and the Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA).

Journal Article J Alzheimers Dis · 2022 BACKGROUND: Population-based studies typically rely on self-reported medical diagnosis (SRMD) of mild cognitive impairment (MCI)/dementia; however, links to objective neurocognitive function have not been established. OBJECTIVE: Examine the association bet ... Full text Link to item Cite

A Cross-Sectional Study to Evaluate the Effects of Age and Duration of HIV Infection on Anxiety and Depression in Cisgender Men.

Journal Article AIDS Behav · January 2022 This observational cross-sectional study of 152 people with HIV (PWH) examined the effects of age and estimated duration of HIV infection (EDI) on depressive and anxiety symptoms. All participants were cisgender men and completed the Profile of Moods State ... Full text Link to item Cite

Subjective cognitive decline and objective cognition among diverse U.S. Hispanics/Latinos: Results from the Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA).

Journal Article Alzheimers Dement · January 2022 INTRODUCTION: Despite increased risk of cognitive decline in Hispanics/Latinos, research on early risk markers of Alzheimer's disease in this group is lacking. Subjective cognitive decline (SCD) may be an early risk marker of pathological aging. We investi ... Full text Link to item Cite

Blood metabolites predicting mild cognitive impairment in the study of Latinos-investigation of neurocognitive aging (HCHS/SOL)

Journal Article Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring · January 1, 2022 Introduction: Blood metabolomics-based biomarkers may be useful to predict measures of neurocognitive aging. Methods: We tested the association between 707 blood metabolites measured in 1451 participants from the Hispanic Community Health Study/Study of La ... Full text Cite

Self-reported subjective cognitive decline is associated with global cognition in a community sample of Latinos/as/x living in the United States.

Journal Article J Clin Exp Neuropsychol · September 2021 INTRODUCTION: Although subjective cognitive decline (SCD) may be an early risk marker of Alzheimer's Disease (AD), research on SCD among Hispanics/Latinos/as/x (henceforth Latinos/as) living in the U.S. is lacking. We investigated if the cross-sectional re ... Full text Link to item Cite

Emotional health outcomes are influenced by sexual minority identity and HIV serostatus.

Journal Article AIDS Care · September 2021 For people living with HIV (PLWH) and sexual minorities (SM), the intersection of identities can compound experiences like stigma and discrimination resulting in poor emotional health. We investigated the separate and interactive associations of HIV serost ... Full text Link to item Cite

Increased Social Interactions Reduce the Association Between Constricted Life-Space and Lower Daily Happiness in Older Adults With and Without HIV: A GPS and Ecological Momentary Assessment Study.

Journal Article Am J Geriatr Psychiatry · August 2021 OBJECTIVE: Older persons with human immunodeficiency virus (HIV) (PWH) are particularly susceptible to life-space restrictions. The aims of this study included: 1) using global positioning system (GPS) derived indicators as an assessment of time spent at h ... Full text Link to item Cite

Characterization of HIV-Associated Neurocognitive Impairment in Middle-Aged and Older Persons With HIV in Lima, Peru

Journal Article Frontiers in Neurology · June 17, 2021 Background: With widespread use of antiretroviral medications, people living with HIV (PWH) are living longer worldwide, increasing their risk of developing neurocognitive impairment (NCI). The proportion of Peruvians over age 60 is expected to increase to ... Full text Cite

The impact of COVID-19 on the well-being and cognition of older adults living in the United States and Latin America

Journal Article EClinicalMedicine · May 1, 2021 Background: In the COVID-19 pandemic, older adults from vulnerable ethnoracial groups are at high risk of infection, hospitalization, and death. We aimed to explore the pandemic's impact on the well-being and cognition of older adults living in the United ... Full text Cite

Gut microbiota dysbiosis is associated with worse emotional states in HIV infection.

Journal Article J Neurovirol · April 2021 The biological mechanisms underlying emotional distress in HIV infection are likely to be complex but remain understudied. We investigated whether dysbiotic signatures in the gut microbiome of persons living with HIV (PLWH) are associated with their emotio ... Full text Link to item Cite

Native Spanish-speaker's test performance and the effects of Spanish-English bilingualism: results from the neuropsychological norms for the U.S.-Mexico Border Region in Spanish (NP-NUMBRS) project.

Journal Article Clin Neuropsychol · February 2021 Objective: We aimed to investigate whether or not demographically-corrected test scores derived from the Neuropsychological Norms for the U.S.-Mexico Border Region in Spanish (NP-NUMBRS) would be less accurate if applied to Spanish-speakers with various de ... Full text Link to item Cite

Updated demographically adjusted norms for the Brief Visuospatial Memory Test-revised and Hopkins Verbal Learning Test-revised in Spanish-speakers from the U.S.-Mexico border region: The NP-NUMBRS project.

Journal Article Clin Neuropsychol · February 2021 We generated demographically adjusted norms for the Brief Visuospatial Memory Test-revised (BVMT-R) and the Hopkins Verbal Learning Test-revised (HVLT-R) for Spanish-speakers from the U.S.-Mexico border region as part of a larger normative project. Methods ... Full text Link to item Cite

Demographically adjusted norms for the Trail Making Test in native Spanish speakers: Results from the neuropsychological norms for the US-Mexico border region in Spanish (NP-NUMBRS) project.

Journal Article Clin Neuropsychol · February 2021 OBJECTIVE: Despite the wide use of the Trail Making Test (TMT), there is a lack of normative data for Spanish speakers living in the USA. Here we describe the development of regional norms for the TMT for native Spanish speakers residing in the Southwest M ... Full text Link to item Cite

The Neuropsychological Norms for the U.S.-Mexico Border Region in Spanish (NP-NUMBRS) Project: Overview and considerations for life span research and evidence-based practice.

Journal Article Clin Neuropsychol · February 2021 OBJECTIVE: This paper summarizes the findings of the Neuropsychological Norms for the U.S.-Mexico Border Region in Spanish (NP-NUMBRS) Project and offers a roadmap for future research. METHODS: The NP-NUMBRS project represents the largest and most comprehe ... Full text Link to item Cite

Demographically-adjusted norms for selected tests of verbal fluency: Results from the Neuropsychological Norms for the US-Mexico Border Region in Spanish (NP-NUMBRS) project.

Journal Article Clin Neuropsychol · February 2021 OBJECTIVE: Verbal fluency tests are sensitive to various disorders affecting the central nervous system and are commonly included in neuropsychological evaluations. We aimed to develop normative data for two verbal fluency tests in a sample of native Spani ... Full text Link to item Cite

Introduction to the Neuropsychological Norms for the US-Mexico Border Region in Spanish (NP-NUMBRS) Project.

Journal Article Clin Neuropsychol · February 2021 OBJECTIVE: The present introduction to the Neuropsychological Norms for the U.S.-Mexico Border Region in Spanish (NP-NUMBRS) project aims to provide an overview of the conceptual framework and rationale that guided the development of this project. METHODS: ... Full text Link to item Cite

Demographically-adjusted norms for the processing speed subtests of the WAIS-III in a Spanish-speaking adult population: Results from the Neuropsychological Norms for the U.S.-Mexico Border Region in Spanish (NP-NUMBRS) project.

Journal Article Clin Neuropsychol · February 2021 OBJECTIVE: The Wechsler Adult Intelligence Scale (WAIS) processing speed subtests are among the most ubiquitous indices of processing speed in the field. The aim of this study was to develop and examine demographically-adjusted normative data for Spanish l ... Full text Link to item Cite

Demographically-adjusted norms for the Grooved Pegboard and Finger Tapping tests in Spanish-speaking adults: Results from the Neuropsychological Norms for the U.S.-Mexico Border Region in Spanish (NP-NUMBRS) Project.

Journal Article Clin Neuropsychol · February 2021 OBJECTIVE: We developed demographically-corrected norms for Spanish-speakers from the U.S.-Mexico border regions of California and Arizona on two tests of motor skills - the Grooved Pegboard Test (Pegboard) and Finger Tapping Test (Tapping) - as part of a ... Full text Link to item Cite

Demographically-adjusted norms for the WAIS-R Block Design and Arithmetic subtests: Results from the Neuropsychological Norms for the US-Mexico Border Region in Spanish (NP-NUMBRS) project.

Journal Article Clin Neuropsychol · February 2021 OBJECTIVE: Wechsler Adult Intelligence Scale (WAIS) Block Design and Arithmetic subtests are frequently used as measures of visuospatial construction and verbal working memory, respectively. As part of a larger test adaptation and norming effort for this p ... Full text Link to item Cite

Demographically-adjusted norms for the paced auditory serial addition test and letter number sequencing test in Spanish-speaking adults: Results from the neuropsychological norms for the U.S.-Mexico border region in Spanish (NP-NUMBRS) Project.

Journal Article Clin Neuropsychol · February 2021 OBJECTIVE: The Paced Auditory Serial Addition Test (PASAT) and Wechsler Adult Intelligence Scale Letter Number Sequencing subtest (LNS) are two commonly used measures of working memory. Demographic variables (age, education, ethnicity, etc.) can impact per ... Full text Link to item Cite

Demographically adjusted normative data for the Halstead category test in a Spanish-speaking adult population: Results from the Neuropsychological Norms for the U.S.-Mexico Border Region in Spanish (NP-NUMBRS).

Journal Article Clin Neuropsychol · February 2021 OBJECTIVE: The present study aimed to develop norms applicable to Spanish-speakers living in the United States (U.S.)- Mexico border region for the Halstead Category Test (HCT), a test of executive function. METHODS: Healthy native Spanish-speakers (N = 25 ... Full text Link to item Cite

The state of neuropsychological test norms for Spanish-speaking adults in the United States.

Journal Article Clin Neuropsychol · February 2021 Objective: The present review paper aimed to identify published neuropsychological test norms developed for Spanish-speakers living in the United States (U.S.). Methods: We conducted a systematic review of the literature via an electronic search on PubMed ... Full text Link to item Cite

Neuropsychological Norms for the U.S.-Mexico Border Region in Spanish (NP-NUMBRS) Project: Methodology and sample characteristics.

Journal Article Clin Neuropsychol · February 2021 OBJECTIVE: The present paper describes the methodology and sample characteristics of the Neuropsychological Norms for the U.S.-Mexico Border Region in Spanish (NP-NUMBRS) Project, which aimed to generate demographically-adjusted norms for a battery of neur ... Full text Link to item Cite

Demographically adjusted normative data for the Wisconsin Card Sorting Test-64 item: Results from the Neuropsychological Norms for the U.S.-Mexico Border Region in Spanish (NP-NUMBRS) project.

Journal Article Clin Neuropsychol · February 2021 OBJECTIVE: The Wisconsin Card Sorting Test (WCST) is among the most commonly used tests of executive functioning. We aimed to generate normative data on the 64-item version of this test (WCST-64) for Spanish-speakers living in the U.S.-Mexico Border region ... Full text Link to item Cite

Neurocognitive impairment in Spanish-speaking Latinos living with HIV in the US: Application of the neuropsychological norms for the US-Mexico border region in Spanish (NP-NUMBRS).

Journal Article Clin Neuropsychol · February 2021 Objective Latinos in the US are at increased risk for HIV-associated neurocognitive impairment (NCI). Most studies of US Latinos living with HIV have included primarily English-speakers only. We investigated the rate, pattern, and correlates of HIV-associa ... Full text Link to item Cite

Normative data for the Brief Spanish-English Verbal Learning Test for representative and diverse Hispanics/Latinos: Results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Journal Article Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring · January 1, 2021 Introduction: Episodic learning and memory performance are crucial components of cognitive assessment. To meet the needs of a diverse Hispanic/Latino population, we aimed to provide normative data on the Brief Spanish-English Verbal Learning Test (B-SEVLT) ... Full text Cite

Psychosocial Factors Associated with Cognitive Function Among Middle-Aged and Older Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos and its Sociocultural Ancillary Study.

Journal Article J Alzheimers Dis · 2021 BACKGROUND: Evidence suggests that psychosocial factors are associated with cognitive health in older adults; however, associations of psychosocial factors with cognition remain largely unexamined in middle-aged and older Hispanics/Latinos. OBJECTIVE: To e ... Full text Link to item Cite

A Culturally Adapted SMS Text Messaging Intervention to Promote Antiretroviral Therapy Adherence Among African Americans: Protocol for a Single-Arm Trial.

Journal Article JMIR Res Protoc · December 10, 2020 BACKGROUND: African Americans are disproportionally affected by HIV and have poorer rates of antiretroviral therapy (ART) adherence compared to other racial or ethnic groups in the United States. Factors associated with poor HIV disease outcomes are common ... Full text Link to item Cite

HIV and three dimensions of Wisdom: Association with cognitive function and physical and mental well-being: For: Psychiatry Research.

Journal Article Psychiatry Res · December 2020 Wisdom is a unique human personality trait with cognitive, affective or compassionate, and reflective dimensions. We evaluated relationships of three specific dimensions of wisdom with cognitive function and physical and mental well-being in people with HI ... Full text Link to item Cite

Association of HIV serostatus and metabolic syndrome with neurobehavioral disturbances.

Journal Article J Neurovirol · December 2020 Metabolic syndrome (MetS), a constellation of related metabolic risk factors, is a common comorbidity associated with cognitive difficulty in people living with HIV (PLWH). Neurobehavioral disturbances (e.g., behavioral manifestations of frontal-subcortica ... Full text Link to item Cite

Older Latino Mental Health: A Complicated Picture

Journal Article Innovation in Aging · January 1, 2020 The aggregation of Latino subgroups in national studies creates an overly simplistic narrative that Latinos are at lower risk of mental illness and that foreign nativity seems protective against mental illness (i.e., immigrant paradox). This broad generali ... Full text Cite

Cognition and Daily Functioning: Results from the Hispanic Community Health Study/Study of Latinos (SOL) and Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA).

Journal Article J Alzheimers Dis · 2020 BACKGROUND: Among older adults, poorer cognitive functioning has been associated with impairments in instrumental activities of daily living (IADLs). However, IADL impairments among older Hispanics/Latinos is poorly understood. OBJECTIVE: To characterize t ... Full text Link to item Cite

Tailoring a mobile health text-messaging intervention to promote antiretroviral therapy adherence among African Americans: A qualitative study.

Journal Article PLoS One · 2020 African Americans are disproportionately affected by HIV and socio-structural barriers that impact antiretroviral (ART) adherence. Two-way text-messaging interventions have shown promise in supporting adherence in US studies of mostly White people living w ... Full text Link to item Cite

Frailty and Neurocognitive Impairment: Impacts on Quality of Life in HIV.

Journal Article J Assoc Nurses AIDS Care · 2020 Little is known about the effects of aging-related conditions on health-related quality of life (HRQOL) among people living with HIV (PLWH). The purpose of our study was to examine the independent effects of neurocognitive impairment (NCI) and frailty and ... Full text Link to item Cite

COMT Val158Met Polymorphism, Cardiometabolic Risk, and Nadir CD4 Synergistically Increase Risk of Neurocognitive Impairment in Men Living With HIV.

Conference J Acquir Immune Defic Syndr · August 15, 2019 OBJECTIVE: The Val allele of the Val158Met single-nucleotide polymorphism of the catechol-o-methyltransferase gene (COMT) results in faster metabolism and reduced bioavailability of dopamine (DA). Among persons living with HIV, Val carriers display neuroco ... Full text Link to item Cite

Metabolic Syndrome and Neurocognitive Deficits in HIV Infection.

Journal Article J Acquir Immune Defic Syndr · May 1, 2019 BACKGROUND: The adverse consequences of HIV and related comorbidities on the central nervous system remain prevalent in the era of combination antiretroviral therapy. Metabolic syndrome (MetS) is a common comorbidity in HIV and has been linked to increased ... Full text Link to item Cite

The cross-sectional association of cognitive stimulation factors and cognitive function among Latino adults in Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Journal Article Alzheimer's and Dementia: Translational Research and Clinical Interventions · January 1, 2019 Introduction: Higher cognitive stimulation (CS) is associated with improved cognition. Sources of CS among Hispanics/Latinos are understudied. Methods: In the Hispanic Community Health Study/Study of Latinos 2008 to 2011 (n = 9438), we used finite mixture ... Full text Cite

Psychosocial Correlates of Frailty Among HIV-Infected and HIV-Uninfected Adults.

Journal Article Behav Med · 2019 Frailty is a geriatric condition characterized by increased vulnerability to physical impairments and limitations that may lead to disabilities and mortality. Although studies in the general population suggest that psychosocial factors affect frailty, less ... Full text Link to item Cite

Alterations in brain TREM2 and Amyloid-β levels are associated with neurocognitive impairment in HIV-infected persons on antiretroviral therapy.

Journal Article J Neurochem · December 2018 Neuroinflammation is a common pathological correlate of HIV-associated neurocognitive disorders (HAND) in individuals on antiretroviral therapy (ART). Triggering receptor expressed on myeloid cells 2 (TREM2) regulates neuroinflammation, clears extracellula ... Full text Link to item Cite

A composite of multisystem injury and neurocognitive impairment in HIV infection: association with everyday functioning.

Journal Article J Neurovirol · October 2018 The Veterans Aging Cohort Study (VACS) Index is a composite marker of multisystem injury among HIV-infected persons. We aimed to examine its cross-sectional association with functional outcomes, after considering neurocognitive impairment (NCI) and other w ... Full text Link to item Cite

Grit and Ambition are Associated with Better Neurocognitive and Everyday Functioning Among Adults Living with HIV.

Journal Article AIDS Behav · October 2018 Grit and ambition are psychological factors that may protect neurocognitive function among persons living with HIV (PLWH). We examined associations between grit, ambition, premorbid verbal intellectual function, and current neurocognitive and everyday func ... Full text Link to item Cite

A Longitudinal Analysis of the Impact of Physical Activity on Neurocognitive Functioning Among HIV-Infected Adults.

Journal Article AIDS Behav · May 2018 Higher levels of physical activity (PA) have been linked to better neurocognitive functioning in many populations. The current study examines the longitudinal association between PA and neurocognitive functioning among HIV-infected and HIV-uninfected perso ... Full text Link to item Cite

Differences in Neurocognitive Impairment Among HIV-Infected Latinos in the United States.

Journal Article J Int Neuropsychol Soc · February 2018 OBJECTIVES: Human immunodeficiency virus (HIV) disproportionately affects Hispanics/Latinos in the United States, yet little is known about neurocognitive impairment (NCI) in this group. We compared the rates of NCI in large well-characterized samples of H ... Full text Link to item Cite

Redefining Aging in HIV Infection Using Phenotypes.

Journal Article Curr HIV/AIDS Rep · October 2017 PURPOSE OF REVIEW: This article critically reviews the utility of "phenotypes" as behavioral descriptors in aging/HIV research that inform biological underpinnings and treatment development. We adopt a phenotypic redefinition of aging conceptualized within ... Full text Link to item Cite

Racial Differences in Neurocognitive Outcomes Post-Stroke: The Impact of Healthcare Variables.

Journal Article J Int Neuropsychol Soc · September 2017 OBJECTIVES: The present study examined differences in neurocognitive outcomes among non-Hispanic Black and White stroke survivors using the NIH Toolbox-Cognition Battery (NIHTB-CB), and investigated the roles of healthcare variables in explaining racial di ... Full text Link to item Cite

Performance of Hispanics and Non-Hispanic Whites on the NIH Toolbox Cognition Battery: the roles of ethnicity and language backgrounds.

Journal Article Clin Neuropsychol · May 2017 OBJECTIVE: This study examined the influence of Hispanic ethnicity and language/cultural background on performance on the NIH Toolbox Cognition Battery (NIHTB-CB). METHOD: Participants included healthy, primarily English-speaking Hispanic (n = 93; Hispanic ... Full text Link to item Cite

Predictors and Barriers to Mental Health Treatment Utilization Among Older Veterans Living With HIV.

Journal Article Prim Care Companion CNS Disord · February 2, 2017 OBJECTIVE: To identify key mood, social, and functional correlates of current participation in mental health treatment and barriers to participation in mental health treatment among older HIV infected (HIV+) veterans. METHODS: HIV+ veterans (N = 150) aged ... Full text Link to item Cite

Managing Depression among Diverse Older Adults in Primary Care: The BRIGHTEN Program.

Journal Article Clin Gerontol · 2017 OBJECTIVES: A variety of specific cultural adaptations have been proposed for older adult and minority mental health interventions. The objective of this study was to determine whether the BRIGHTEN Program, an individually tailored, interdisciplinary "virt ... Full text Link to item Cite

The Veterans Aging Cohort Study (VACS) Index and Neurocognitive Change: A Longitudinal Study.

Journal Article Clin Infect Dis · September 1, 2016 BACKGROUND: The Veterans Aging Cohort Study (VACS) Index, a composite marker of disease severity among human immunodeficiency virus (HIV)-infected persons, has been associated with concurrent risk for neurocognitive impairment (NCI). The present study exam ... Full text Link to item Cite

Impaired personal trait knowledge, but spared other-person trait knowledge, in an individual with bilateral damage to the medial prefrontal cortex.

Journal Article Neuropsychologia · August 2016 Functional neuroimaging has revealed that in healthy adults retrieval of personal trait knowledge is associated with increased activation in the medial prefrontal cortex (mPFC). Separately, neuropsychology has shown that the self-referential nature of memo ... Full text Link to item Cite

The impact of ethnicity/race on the association between the Veterans Aging Cohort Study (VACS) Index and neurocognitive function among HIV-infected persons.

Journal Article J Neurovirol · August 2016 The Veterans Aging Cohort Study (VACS) Index was developed as a risk index for health outcomes in HIV, and it has been consistently associated with mortality. It shows a significant, yet relatively weak, association with neurocognitive impairment, and litt ... Full text Link to item Cite

Demographically Corrected Normative Standards for the Spanish Language Version of the NIH Toolbox Cognition Battery.

Journal Article J Int Neuropsychol Soc · March 2016 Hispanics are the fastest growing ethnicity in the United States, yet there are limited well-validated neuropsychological tools in Spanish, and an even greater paucity of normative standards representing this population. The Spanish NIH Toolbox Cognition B ... Full text Link to item Cite

Predictors of attrition in a cohort study of HIV infection and methamphetamine dependence

Journal Article Journal of Substance Use · November 2, 2015 Longitudinal cohort studies of HIV and substance use disorders play an important role in understanding these conditions, but high rates of attrition can threaten their integrity and generalizability. This study aimed to identify factors associated with att ... Full text Cite

Physical Activity is Associated with Better Neurocognitive and Everyday Functioning Among Older Adults with HIV Disease.

Journal Article AIDS Behav · August 2015 We examined the association between physical activity (PA), neurocognitive impairment (NCI), and instrumental activities of daily living (IADLs) among older HIV+ persons. One hundred older HIV+ adults completed the International Physical Activity Questionn ... Full text Link to item Cite

Early life development in a multiethnic sample and the relation to late life cognition.

Journal Article J Gerontol B Psychol Sci Soc Sci · July 2015 OBJECTIVES: Poor quality of early life conditions has been associated with poorer late life cognition and increased risk of dementia. Early life physical development can be captured using adult measures of height and head circumference. Availability of res ... Full text Link to item Cite

Reply to Haddow et al.

Journal Article Clin Infect Dis · May 1, 2015 Full text Link to item Cite

Neurocognitive change in the era of HIV combination antiretroviral therapy: the longitudinal CHARTER study.

Journal Article Clin Infect Dis · February 1, 2015 BACKGROUND: Human immunodeficiency virus (HIV)-associated neurocognitive disorders (HAND) can show variable clinical trajectories. Previous longitudinal studies of HAND typically have been brief, did not use adequate normative standards, or were conducted ... Full text Link to item Cite

Differences in life satisfaction among older community-dwelling Hispanics and non-Hispanic Whites.

Journal Article Aging Ment Health · 2015 OBJECTIVES: Hispanics are the fastest growing ethnic/racial group of the older adult population in the United States, yet little is known about positive mental health in this group. We examined differences in life satisfaction between demographically match ... Full text Link to item Cite

Life experience and demographic influences on cognitive function in older adults.

Journal Article Neuropsychology · November 2014 OBJECTIVE: We examined the influence of a broad spectrum of life experiences on longitudinal cognitive trajectories in a demographically diverse sample of older adults. METHOD: Participants were 333 educationally, ethnically, and cognitively diverse older ... Full text Link to item Cite

The veterans aging cohort study index is associated with concurrent risk for neurocognitive impairment.

Journal Article J Acquir Immune Defic Syndr · February 1, 2014 OBJECTIVE: The Veterans Aging Cohort Study (VACS) Index is predictive of mortality and combines age, traditional HIV biomarkers (HIV-1 plasma RNA and current CD4 count), and non-HIV biomarkers (indicators of renal and liver function, anemia, and hepatitis ... Full text Link to item Cite

"Frontal systems" behaviors in comorbid human immunodeficiency virus infection and methamphetamine dependency.

Journal Article Psychiatry Res · January 30, 2014 Human immunodeficiency virus (HIV) infection and methamphetamine (MA) dependence are associated with neural injury preferentially involving frontostriatal circuits. Little is known, however, about how these commonly comorbid conditions impact behavioral pr ... Full text Link to item Cite

Attention-deficit/hyperactivity disorder among chronic methamphetamine users: frequency, persistence, and adverse effects on everyday functioning.

Journal Article Addict Behav · December 2013 AIMS: Attention-Deficit/Hyperactivity Disorder (ADHD) is widely regarded as a common comorbidity of methamphetamine (MA) dependence, but the frequency, persistence, and real-world impact of ADHD among MA users are not known. METHODS: Four hundred individua ... Full text Link to item Cite

Physical exercise is associated with less neurocognitive impairment among HIV-infected adults.

Journal Article J Neurovirol · October 2013 Neurocognitive impairment (NCI) remains prevalent in HIV infection. Randomized trials have shown that physical exercise improves NCI in non-HIV-infected adults, but data on HIV-infected populations are limited. Community-dwelling HIV-infected participants ... Full text Link to item Cite

Association between cognitive activity and cognitive function in older Hispanics.

Journal Article J Int Neuropsychol Soc · November 2012 There is limited research on the association between participation in cognitively stimulating activity and cognitive function in older Hispanics. The main purpose of the present study was to explore whether frequency of cognitive activity and its associati ... Full text Link to item Cite

Community long-term care teams: Assessing team fitness

Journal Article Clinical Gerontologist · October 1, 2011 Although long-term care is often conceptualized as institutional living, the majority of long-term care is provided in the community through primary care. The BRIGHTEN program (Bridging Resources of an Interdisciplinary Geriatric Health Team via Electronic ... Full text Cite

Differential patterns of cognitive decline in anterior and posterior white matter hyperintensity progression.

Journal Article Stroke · September 2010 BACKGROUND AND PURPOSE: White matter hyperintensities (WMHs) found on brain MRI in elderly individuals are largely thought to be due to microvascular disease, and its progression has been associated with cognitive decline. The present study sought to deter ... Full text Link to item Cite

Repeatable battery for the assessment of neuropsychological status effort index performance in a medically ill geriatric sample.

Journal Article Arch Clin Neuropsychol · May 2009 Using a sample of 44 clinically referred, non-litigating, older adults, we evaluated the Repeatable Battery for the Assessment of Neuropsychological Status Effort Index [RBANS EI; Silverberg, N. D., Wertheimer, J. C., & Fichtenberg, N. L. (2007). An effort ... Full text Link to item Cite

Semantic and self-referential processing of positive and negative trait adjectives in older adults.

Journal Article Memory · February 2009 The beneficial effects of self-referential processing on memory have been demonstrated in numerous experiments with younger adults but have rarely been studied in older individuals. In the present study we tested young people, younger-older adults, and old ... Full text Link to item Cite