Overview
Current research interests include:
1. The relationship between white matter patency, functional connectivity (fMRI) and neurocognitive function following cardiac surgery.
2. The relationship between global and regional cortical beta-amyloid deposition and postoperative cognitive decline.
3. The effect of lidocaine infusion upon neurocognitive function following cardiac surgery.
4. The association between genotype and outcome after cardiac surgery.
5. Atrial fibrillation following cardiopulmonary bypass.
1. The relationship between white matter patency, functional connectivity (fMRI) and neurocognitive function following cardiac surgery.
2. The relationship between global and regional cortical beta-amyloid deposition and postoperative cognitive decline.
3. The effect of lidocaine infusion upon neurocognitive function following cardiac surgery.
4. The association between genotype and outcome after cardiac surgery.
5. Atrial fibrillation following cardiopulmonary bypass.
Current Appointments & Affiliations
Jerry Reves, M.D. Distinguished Professor of Cardiac Anesthesiology
·
2011 - Present
Anesthesiology, Cardiothoracic,
Anesthesiology
Professor of Anesthesiology
·
2007 - Present
Anesthesiology, Cardiothoracic,
Anesthesiology
Chair of Anesthesiology
·
2015 - Present
Anesthesiology,
Clinical Science Departments
Core Faculty in Innovation & Entrepreneurship
·
2018 - Present
Duke Innovation & Entrepreneurship,
University Initiatives & Academic Support Units
Recent Publications
Associations between anaesthetic dose-adjusted intraoperative EEG alpha power, processing speed, and postoperative delirium: analysis of data from three prospective studies.
Journal Article Br J Anaesth · July 2025 BACKGROUND: We previously have shown that low intraoperative EEG alpha power is associated with impaired preoperative cognition, a delirium risk factor, and that intraoperative anaesthetic-dose-adjusted EEG bispectral index values were associated with a fo ... Full text Link to item CiteGeneral anesthesia-activated neurons in the central amygdala mediate antinociception: Distinct roles in acute versus chronic phases of nerve injury.
Journal Article Anesthesiology · May 7, 2025 BACKGROUND: General anesthesia (GA), such as isoflurane, induces analgesia (loss of pain) and loss of consciousness through mechanisms that are not fully understood. A distinct population of GABAergic neurons has been recently identified in the central amy ... Full text Link to item CiteErratum: The Role of Sleep Apnea in Postoperative Neurocognitive Disorders Among Older Noncardiac Surgery Patients: A Prospective Cohort Study.
Journal Article Anesth Analg · May 1, 2025 Full text Link to item CiteRecent Grants
Neurocognition & Greater Maintenance of Sinus Rhythm in AF (NOGGIN AF)
Clinical TrialPrincipal Investigator · Awarded by National Institute on Aging · 2021 - 2026The Role of the Aging Brain-Heart-Immune Axis in Postoperative Delirium
ResearchMentor · Awarded by National Institutes of Health · 2022 - 2025FAER GEMSSTAR Supplement (rolling deadline)
ResearchMentor · Awarded by Foundation for Anesthesia Education and Research · 2023 - 2025View All Grants
Education, Training & Certifications
University of Massachusetts, Amherst ·
2013
M.B.A.
Duke University, School of Medicine ·
2008
M.H.S.
University of Texas, Dallas ·
1986
M.D.