Joseph P. Mathew | Scholars@Duke

Joseph P. Mathew
Jerry Reves, M.D. Professor of Cardiac Anesthesiology

Current research interests include:
1. The relationship between white matter patency, functional connectivity (fMRI) and neurocognitive function following cardiac surgery.
2. The relationship between global and regional cortical beta-amyloid deposition and postoperative cognitive decline.
3. The effect of lidocaine infusion upon neurocognitive function following cardiac surgery.
4. The association between genotype and outcome after cardiac surgery.
5. Atrial fibrillation following cardiopulmonary bypass.

Current Appointments & Affiliations

Jerry Reves, M.D. Professor of Cardiac Anesthesiology, Anesthesiology, Cardiothoracic, Anesthesiology 2011
Professor of Anesthesiology, Anesthesiology, Cardiothoracic, Anesthesiology 2007
Chair of Anesthesiology, Anesthesiology, Clinical Science Departments 2015
Core Faculty in Innovation & Entrepreneurship, Duke Innovation & Entrepreneurship, Initiatives 2018

Contact Information

2301 Erwin Road, 5692 Hafs Building, Durham, NC 27710
Box 3094 Med Ctr, Durham, NC 27710
mathe014@mc.duke.edu (919) 681-6646

Background
Education, Training, & Certifications
- M.B.A., University of Massachusetts at Amherst 2013
- M.H.S., Duke University School of Medicine 2008
- Assistant and Associate Professor, Anesthesiology, Yale University 1991 - 1998
- Fellow-Cardiovascular, Anesthesiology, Yale University 1990 - 1991
- Residency, Anesthesiology, Yale University 1987 - 1990
- M.D., University of Texas at Dallas 1986
Duke Appointment History
- Interim Chair of Anesthesiology, Anesthesiology, Clinical Science Departments 2014 - 2015
- Chief, Division of Cardiac Anesthesiology, Anesthesiology, Cardiothoracic, Anesthesiology 2003 - 2013
- Associate Professor of Anesthesiology, Anesthesiology, Cardiothoracic, Anesthesiology 2004 - 2007
- Associate Professor of Anesthesiology, Anesthesiology, Cardiothoracic, Anesthesiology 1998 - 2004
- Instructor, Temporary of Anesthesiology, Anesthesiology, Cardiothoracic, Anesthesiology 1998
Research
Selected Grants
- Neuro-inflammation in Postoperative Cognitive Dysfunction: CSF and fMRI Studies awarded by National Institutes of Health 2017 - 2022
- Cognitive Effects of Body Temperature During Hypothermic Circulatory Arrest awarded by National Institutes of Health 2016 - 2021
- The Role of Obstructive Sleep Apnea in Neuroinflammation and Postoperative Cognitive Dysfunction awarded by Foundation for Anesthesia Education and Research 2019
- Platelets as regulators of inflammation and tissue injury after cardiac surgery awarded by American Heart Association 2015 - 2019
- Network for Cardiothoracic Surgical Investigations in Cardiovascular Medicine-Consortium Agreement awarded by Mount Sinai School of Medicine 2013 - 2019
- The Significance of Perioperative Changes in CSF tau levels in the Elderly awarded by National Institutes of Health 2015 - 2018
- Core Clinical Centers for the CTSN awarded by National Institutes of Health 2007 - 2018
- AA Contract: Innovative Educational Programs awarded by Mednax, Inc. 2015 - 2018
- The trajectory and significance of perioperative changes in AD biomarkers awarded by International Anesthesia Research Society 2014 - 2018
- Platelet/Mast Cell Interactions as Determinants of End-Organ Injury in Cardiac Surgery awarded by National Institutes of Health 2015 - 2017
- Lidocaine for Neuroprotection During Cardiac Surgery awarded by National Institutes of Health 2009 - 2016
- Functional connectivity changes in attention networks after cardiac surgery awarded by National Institutes of Health 2012 - 2015
- Cortical Beta-amyloid Levels and Neurocognitive Performance After Cardiac Surgery awarded by National Institutes of Health 2011 - 2014
- Pilot Study of the Feasibility of Multicenter NIRS Data Collection and Interventions for Desaturation in Cardiac Surgery awarded by Johns Hopkins University 2013 - 2014
- PeriOperative Interventional Neuroprotection Trial POINT awarded by National Institutes of Health 2001 - 2008
- Genetics, Inflammation & Post-op Cognitive Dysfunction awarded by National Institutes of Health 1999 - 2006
- Aging And Cognition After Cardiac Surgery awarded by National Institutes of Health 1999 - 2004
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Waldron, NH, Cooter, M, Haney, JC, Schroder, JN, Gaca, JG, Lin, SS, Sigurdsson, MI, Fudim, M, Podgoreanu, MV, Stafford-Smith, M, Milano, CA, Piccini, JP, and Mathew, JP. "Temporary autonomic modulation with botulinum toxin type A to reduce atrial fibrillation after cardiac surgery." Heart Rhythm 16, no. 2 (February 2019): 178-184. Full Text
  - Berger, M, Oyeyemi, D, Olurinde, MO, Whitson, HE, Weinhold, KJ, Woldorff, MG, Lipsitz, LA, Moretti, E, Giattino, CM, Roberts, KC, Zhou, J, Bunning, T, Ferrandino, M, Scheri, RP, Cooter, M, Chan, C, Cabeza, R, Browndyke, JN, Murdoch, DM, Devinney, MJ, Shaw, LM, Cohen, HJ, Mathew, JP, and INTUIT Investigators, . "The INTUIT Study: Investigating Neuroinflammation Underlying Postoperative Cognitive Dysfunction." Journal of the American Geriatrics Society (January 23, 2019). Full Text Open Access Copy
  - Grantham, A, Hauck, J, Stafford-Smith, M, Mathew, JP, and Thompson, A. "Implementation of an Innovative Residency Leadership Development Curriculum." A&A Practice (January 11, 2019). Full Text
  - Blackstone, EH, Chang, HL, Rajeswaran, J, Parides, MK, Ishwaran, H, Li, L, Ehrlinger, J, Gelijns, AC, Moskowitz, AJ, Argenziano, M, DeRose, JJ, Couderc, J-P, Balda, D, Dagenais, F, Mack, MJ, Ailawadi, G, Smith, PK, Acker, MA, O'Gara, PT, Gillinov, AM, and Cardiothoracic Surgical Trials Network Investigators, . "Biatrial maze procedure versus pulmonary vein isolation for atrial fibrillation during mitral valve surgery: New analytical approaches and end points." The Journal of Thoracic and Cardiovascular Surgery 157, no. 1 (January 2019): 234-243.e9. Full Text
  - Muehlschlegel, JD, Burrage, PS, Ngai, JY, Prutkin, JM, Huang, C-C, Xu, X, Chae, SH, Bollen, BA, Piccini, JP, Schwann, NM, Mahajan, A, Ruel, M, Body, SC, Sellke, FW, Mathew, J, and O'Brien, B. "Society of Cardiovascular Anesthesiologists/European Association of Cardiothoracic Anaesthetists Practice Advisory for the Management of Perioperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery." Anesthesia and Analgesia 128, no. 1 (January 2019): 33-42. Full Text
  - O'Brien, B, Burrage, PS, Ngai, JY, Prutkin, JM, Huang, C-C, Xu, X, Chae, SH, Bollen, BA, Piccini, JP, Schwann, NM, Mahajan, A, Ruel, M, Body, SC, Sellke, FW, Mathew, J, and Muehlschlegel, JD. "Society of Cardiovascular Anesthesiologists/European Association of Cardiothoracic Anaesthetists Practice Advisory for the Management of Perioperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery." Journal of Cardiothoracic and Vascular Anesthesia 33, no. 1 (January 2019): 12-26. Full Text
  - Smith, PJ, Browndyke, JN, Monge, ZA, Harshbarger, TB, James, ML, Gaca, JG, Alexander, JH, Berger, MM, Newman, MF, Milano, CA, Mathew, JP, and Neurologic Outcomes Research Group (NORG), . "Longitudinal Changes in Regional Cerebral Perfusion and Cognition After Cardiac Operation." The Annals of Thoracic Surgery 107, no. 1 (January 2019): 112-118. Full Text Open Access Copy
  - Berger, M, Schenning, KJ, Brown, CH, Deiner, SG, Whittington, RA, Eckenhoff, RG, Angst, MS, Avramescu, S, Bekker, A, Brzezinski, M, Crosby, G, Culley, DJ, Eckenhoff, M, Eriksson, LI, Evered, L, Ibinson, J, Kline, RP, Kofke, A, Ma, D, Mathew, JP, Maze, M, Orser, BA, Price, CC, Scott, DA, Silbert, B, Su, D, Terrando, N, Wang, D-S, Wei, H, Xie, Z, Zuo, Z, and Perioperative Neurotoxicity Working Group, . "Best Practices for Postoperative Brain Health: Recommendations From the Fifth International Perioperative Neurotoxicity Working Group." Anesthesia and Analgesia 127, no. 6 (December 2018): 1406-1413. Full Text
  - Suarez-Roca, H, Klinger, RY, Podgoreanu, MV, Ji, R-R, Sigurdsson, MI, Waldron, N, Mathew, JP, and Maixner, W. "Contribution of Baroreceptor Function to Pain Perception and Perioperative Outcomes." Anesthesiology (November 5, 2018). Full Text
  - Berger, M, Terrando, N, Smith, SK, Browndyke, JN, Newman, MF, and Mathew, JP. "Neurocognitive Function after Cardiac Surgery: From Phenotypes to Mechanisms." Anesthesiology 129, no. 4 (October 2018): 829-851. Full Text
  - Devinney, MJ, Mathew, JP, and Berger, M. "Postoperative Delirium and Postoperative Cognitive Dysfunction: Two Sides of the Same Coin?." Anesthesiology 129, no. 3 (September 2018): 389-391. Full Text
  - Waldron, NH, Cooter, M, Piccini, JP, Anstrom, KJ, Klinger, RY, Kertai, MD, Podgoreanu, MV, Stafford-Smith, M, Newman, MF, and Mathew, JP. "Predictive ability of perioperative atrial fibrillation risk indices in cardiac surgery patients: a retrospective cohort study." Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie 65, no. 7 (July 2018): 786-796. Full Text
  - Gulack, BC, Kirkwood, KA, Shi, W, Smith, PK, Alexander, JH, Burks, SG, Gelijns, AC, Thourani, VH, Bell, D, Greenberg, A, Goldfarb, SD, Mayer, ML, Bowdish, ME, and Cardiothoracic Surgical Trials Network (CTSN), . "Secondary surgical-site infection after coronary artery bypass grafting: A multi-institutional prospective cohort study." The Journal of Thoracic and Cardiovascular Surgery 155, no. 4 (April 2018): 1555-1562.e1. Full Text
  - Klinger, RY, James, OG, Borges-Neto, S, Bisanar, T, Li, Y-J, Qi, W, Berger, M, Terrando, N, Newman, MF, Doraiswamy, PM, Mathew, JP, Alzheimer’s Disease Neuroimaging Initiative (ADNI) Study Group, , and Neurologic Outcomes Research Group (NORG), . "18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery." Anesthesiology 128, no. 4 (April 2018): 728-744. Full Text
  - Browndyke, JN, Berger, M, Smith, PJ, Harshbarger, TB, Monge, ZA, Panchal, V, Bisanar, TL, Glower, DD, Alexander, JH, Cabeza, R, Welsh-Bohmer, K, Newman, MF, Mathew, JP, and Duke Neurologic Outcomes Research Group (NORG), . "Task-related changes in degree centrality and local coherence of the posterior cingulate cortex after major cardiac surgery in older adults." Human Brain Mapping 39, no. 2 (February 2018): 985-1003. Full Text Open Access Copy
  - Fudim, M, Boortz-Marx, R, Ganesh, A, Waldron, NH, Qadri, YJ, Patel, CB, Milano, CA, Sun, AY, Mathew, JP, and Piccini, JP. "Stellate ganglion blockade for the treatment of refractory ventricular arrhythmias: A systematic review and meta-analysis." Journal of Cardiovascular Electrophysiology 28, no. 12 (December 2017): 1460-1467. (Review) Full Text
  - Kertai, MD, Cooter, M, Pollard, RJ, Buhrman, W, Aronson, S, Mathew, JP, and Stafford-Smith, M. "Is Compliance With Surgical Care Improvement Project Cardiac (SCIP-Card-2) Measures for Perioperative β-Blockers Associated With Reduced Incidence of Mortality and Cardiovascular-Related Critical Quality Indicators After Noncardiac Surgery?." Anesthesia and analgesia (November 30, 2017). Full Text
  - Schroeder, RA, Pollard, R, Dhakal, I, Cooter, M, Aronson, S, Grichnik, K, Buhrman, W, Kertai, MD, Mathew, JP, and Stafford-Smith, M. "Temporal Trends in Difficult and Failed Tracheal Intubation in a Regional Community Anesthetic Practice." Anesthesiology (November 20, 2017). Full Text
  - Karhausen, JA, Smeltz, AM, Akushevich, I, Cooter, M, Podgoreanu, MV, Stafford-Smith, M, Martinelli, SM, Fontes, ML, and Kertai, MD. "Platelet Counts and Postoperative Stroke After Coronary Artery Bypass Grafting Surgery." Anesthesia and Analgesia 125, no. 4 (October 2017): 1129-1139. Full Text Open Access Copy
  - Englum, BR, He, X, Gulack, BC, Ganapathi, AM, Mathew, JP, Brennan, JM, Reece, TB, Keeling, WB, Leshnower, BG, Chen, EP, Jacobs, JP, Thourani, VH, and Hughes, GC. "Hypothermia and cerebral protection strategies in aortic arch surgery: a comparative effectiveness analysis from the STS Adult Cardiac Surgery Database." European Journal of Cardio Thoracic Surgery : Official Journal of the European Association for Cardio Thoracic Surgery 52, no. 3 (September 2017): 492-498. Full Text
  - Manning, MW, Cooter, M, Mathew, J, Alexander, J, Peterson, E, Ferguson, TB, Lopes, R, and Podgoreanu, M. "Angiotensin Receptor Blockade Improves Cardiac Surgical Outcomes in Patients With Metabolic Syndrome." The Annals of Thoracic Surgery 104, no. 1 (July 2017): 98-105. Full Text
  - Waldron, NH, Klinger, RY, Hartwig, MG, Snyder, LD, Daubert, JP, and Mathew, JP. "Adverse outcomes associated with postoperative atrial arrhythmias after lung transplantation: A meta-analysis and systematic review of the literature." Clinical transplantation 31, no. 4 (April 2017). (Review) Full Text
  - Smith, PJ, Blumenthal, JA, Snyder, LD, Mathew, JP, Durheim, MT, Hoffman, BM, Rivelli, SK, and Palmer, SM. "Depressive symptoms and early mortality following lung transplantation: A pilot study." Clinical Transplantation 31, no. 2 (February 2017). Full Text
  - Berger, M, Ponnusamy, V, Greene, N, Cooter, M, Nadler, JW, Friedman, A, McDonagh, DL, Laskowitz, DT, Newman, MF, Shaw, LM, Warner, DS, Mathew, JP, James, ML, and MAD-PIA Investigators, . "The Effect of Propofol vs. Isoflurane Anesthesia on Postoperative Changes in Cerebrospinal Fluid Cytokine Levels: Results from a Randomized Trial." Frontiers in Immunology 8 (January 2017): 1528-null. Full Text
  - Browndyke, JN, Berger, M, Harshbarger, TB, Smith, PJ, White, W, Bisanar, TL, Alexander, JH, Gaca, JG, Welsh-Bohmer, K, Newman, MF, and Mathew, JP. "Resting-State Functional Connectivity and Cognition After Major Cardiac Surgery in Older Adults without Preoperative Cognitive Impairment: Preliminary Findings." Journal of the American Geriatrics Society 65, no. 1 (January 2017): e6-e12. Full Text Open Access Copy
  - Giattino, CM, Gardner, JE, Sbahi, FM, Roberts, KC, Cooter, M, Moretti, E, Browndyke, JN, Mathew, JP, Woldorff, MG, Berger, M, and MADCO-PC Investigators, . "Intraoperative Frontal Alpha-Band Power Correlates with Preoperative Neurocognitive Function in Older Adults." Frontiers in Systems Neuroscience 11 (January 2017): 24-null. Full Text Open Access Copy
  - Kertai, MD, Cheruku, S, Qi, W, Li, Y-J, Hughes, GC, Mathew, JP, and Karhausen, JA. "Mast cell activation and arterial hypotension during proximal aortic repair requiring hypothermic circulatory arrest." The Journal of thoracic and cardiovascular surgery 153, no. 1 (January 2017): 68-76.e2. Full Text Open Access Copy
  - Zhang, Z, Ma, Q, Shah, B, Mackensen, GB, Lo, DC, Mathew, JP, Podgoreanu, MV, and Terrando, N. "Neuroprotective Effects of Annexin A1 Tripeptide after Deep Hypothermic Circulatory Arrest in Rats." Frontiers in Immunology 8 (January 2017): 1050-null. Full Text
  - Klinger, RY, Cooter, M, Berger, M, Podgoreanu, MV, Stafford-Smith, M, Ortel, TL, Welsby, IJ, Levy, JH, Rinder, HM, Newman, MF, Mathew, JP, and Neurologic Outcomes Research Group (NORG) of The Duke Heart Center, . "Effect of intravenous lidocaine on the transcerebral inflammatory response during cardiac surgery: a randomized-controlled trial." Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie 63, no. 11 (November 2016): 1223-1232. Full Text
  - Zhang, M-D, Barde, S, Yang, T, Lei, B, Eriksson, LI, Mathew, JP, Andreska, T, Akassoglou, K, Harkany, T, Hökfelt, TGM, and Terrando, N. "Orthopedic surgery modulates neuropeptides and BDNF expression at the spinal and hippocampal levels." Proceedings of the National Academy of Sciences of the United States of America 113, no. 43 (October 10, 2016): E6686-E6695. Full Text
  - Kertai, MD, Zhou, S, Karhausen, JA, Cooter, M, Jooste, E, Li, Y-J, White, WD, Aronson, S, Podgoreanu, MV, Gaca, J, Welsby, IJ, Levy, JH, Stafford-Smith, M, Mathew, JP, and Fontes, ML. "In Reply." Anesthesiology 125, no. 2 (August 2016): 438-439. (Letter) Full Text
  - Berger, M, Nadler, JW, Friedman, A, McDonagh, DL, Bennett, ER, Cooter, M, Qi, W, Laskowitz, DT, Ponnusamy, V, Newman, MF, Shaw, LM, Warner, DS, Mathew, JP, James, ML, and MAD-PIA trial team, . "The Effect of Propofol Versus Isoflurane Anesthesia on Human Cerebrospinal Fluid Markers of Alzheimer's Disease: Results of a Randomized Trial." Journal of Alzheimer'S Disease : Jad 52, no. 4 (April 2016): 1299-1310. Full Text Open Access Copy
  - Kertai, MD, Ji, Y, Li, Y-J, Mathew, JP, Daubert, JP, Podgoreanu, MV, and PEGASUS Investigative Team, . "Interleukin-1β gene variants are associated with QTc interval prolongation following cardiac surgery: a prospective observational study." Canadian journal of anaesthesia = Journal canadien d'anesthesie 63, no. 4 (April 2016): 397-410. Full Text
  - Kertai, MD, Qi, W, Li, Y-J, Lombard, FW, Liu, Y, Smith, MP, Stafford-Smith, M, Newman, MF, Milano, CA, Mathew, JP, Podgoreanu, MV, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "Gene signatures of postoperative atrial fibrillation in atrial tissue after coronary artery bypass grafting surgery in patients receiving β-blockers." Journal of Molecular and Cellular Cardiology 92 (March 2016): 109-115. Full Text
  - Keenan, JE, Wang, H, Ganapathi, AM, Englum, BR, Kale, E, Mathew, JP, Husain, AM, and Hughes, GC. "Electroencephalography During Hemiarch Replacement With Moderate Hypothermic Circulatory Arrest." The Annals of Thoracic Surgery 101, no. 2 (February 2016): 631-637. Full Text
  - Kertai, MD, Zhou, S, Karhausen, JA, Cooter, M, Jooste, E, Li, Y-J, White, WD, Aronson, S, Podgoreanu, MV, Gaca, J, Welsby, IJ, Levy, JH, Stafford-Smith, M, Mathew, JP, and Fontes, ML. "Platelet Counts, Acute Kidney Injury, and Mortality after Coronary Artery Bypass Grafting Surgery." Anesthesiology 124, no. 2 (February 2016): 339-352. Full Text Open Access Copy
  - Smith, PJ, Blumenthal, JA, Hoffman, BM, Rivelli, SK, Palmer, SM, Davis, RD, and Mathew, JP. "Reduced Cerebral Perfusion Pressure during Lung Transplant Surgery Is Associated with Risk, Duration, and Severity of Postoperative Delirium." Annals of the American Thoracic Society 13, no. 2 (February 2016): 180-187. Full Text
  - Klinger, RY, Thunberg, CA, White, WD, Fontes, M, Waldron, NH, Piccini, JP, Hughes, GC, Podgoreanu, MV, Stafford-Smith, M, Newman, MF, and Mathew, JP. "Intraoperative Magnesium Administration Does Not Reduce Postoperative Atrial Fibrillation After Cardiac Surgery." Anesthesia and Analgesia 121, no. 4 (October 2015): 861-867. Full Text
  - Stafford-Smith, M, Li, Y-J, Mathew, JP, Li, Y-W, Ji, Y, Phillips-Bute, BG, Milano, CA, Newman, MF, Kraus, WE, Kertai, MD, Shah, SH, Podgoreanu, MV, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "Genome-wide association study of acute kidney injury after coronary bypass graft surgery identifies susceptibility loci." Kidney international 88, no. 4 (October 2015): 823-832. Full Text Open Access Copy
  - Berger, M, Nadler, JW, Browndyke, J, Terrando, N, Ponnusamy, V, Cohen, HJ, Whitson, HE, and Mathew, JP. "Postoperative Cognitive Dysfunction: Minding the Gaps in Our Knowledge of a Common Postoperative Complication in the Elderly." Anesthesiology Clinics 33, no. 3 (September 2015): 517-550. (Review) Full Text
  - Kertai, MD, Li, Y-J, Ji, Y, Qi, W, Lombard, FW, Shah, SH, Kraus, WE, Stafford-Smith, M, Newman, MF, Milano, CA, Waldron, N, Podgoreanu, MV, Mathew, JP, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "Genome-wide association study of new-onset atrial fibrillation after coronary artery bypass grafting surgery." American heart journal 170, no. 3 (September 2015): 580-90.e28. Full Text
  - Bartels, K, Li, Y-J, Li, Y-W, White, WD, Laskowitz, DT, Kertai, MD, Stafford-Smith, M, Podgoreanu, MV, Newman, MF, and Mathew, JP. "Apolipoprotein epsilon 4 genotype is associated with less improvement in cognitive function five years after cardiac surgery: a retrospective cohort study." Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie 62, no. 6 (June 2015): 618-626. Full Text
  - Berger, M, Browndyke, J, and Mathew, JP. "Intraoperative Glycemic Control to Prevent Delirium after Cardiac Surgery: Steering a Course between Scylla and Charybdis." Anesthesiology 122, no. 6 (June 2015): 1186-1188. Full Text
  - Kertai, MD, Li, Y-J, Li, Y-W, Ji, Y, Alexander, J, Newman, MF, Smith, PK, Joseph, D, Mathew, JP, Podgoreanu, MV, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "Genome-wide association study of perioperative myocardial infarction after coronary artery bypass surgery." BMJ open 5, no. 5 (May 6, 2015): e006920-. Full Text Open Access Copy
  - Smith, PJ, Rivelli, SK, Waters, AM, Hoyle, A, Durheim, MT, Reynolds, JM, Flowers, M, Davis, RD, Palmer, SM, Mathew, JP, and Blumenthal, JA. "Delirium affects length of hospital stay after lung transplantation." Journal of critical care 30, no. 1 (February 2015): 126-129. Full Text
  - Smith, PJ, Rivelli, SK, Waters, AM, Hoyle, A, Durheim, MT, Reynolds, JM, Flowers, M, Davis, RD, Palmer, SM, Mathew, JP, and Blumenthal, JA. "Delirium affects length of hospital stay after lung transplantation." Journal of Critical Care 30, no. 1 (January 1, 2015): 126-129. Full Text
  - Berger, M, Burke, J, Eckenhoff, R, and Mathew, J. "Alzheimer's disease, anesthesia, and surgery: a clinically focused review." Journal of Cardiothoracic and Vascular Anesthesia 28, no. 6 (December 2014): 1609-1623. (Review) Full Text
  - Hauck, J, Osho, A, Castleberry, A, Hartwig, M, Reddy, L, Phillips-Bute, B, Swaminathan, M, Mathew, J, and Stafford-Smith, M. "Acute kidney injury after ex vivo lung perfusion (EVLP)." Transplantation proceedings 46, no. 10 (December 2014): 3598-3602. Full Text
  - Nicoara, A, Holmquist, F, Raggains, C, and Mathew, JP. "Anesthesia for catheter ablation procedures." Journal of Cardiothoracic and Vascular Anesthesia 28, no. 6 (December 2014): 1589-1603. (Review) Full Text
  - Smith, PJ, Rivelli, S, Waters, A, Reynolds, J, Hoyle, A, Flowers, M, Davis, RD, Palmer, SM, Mathew, J, Durheim, M, and Blumenthal, JA. "Neurocognitive changes after lung transplantation." Annals of the American Thoracic Society 11, no. 10 (December 2014): 1520-1527. Full Text
  - Bartels, K, Ma, Q, Venkatraman, TN, Campos, CR, Smith, L, Cannon, RE, Podgoreanu, MV, Lascola, CD, Miller, DS, and Mathew, JP. "Effects of deep hypothermic circulatory arrest on the blood brain barrier in a cardiopulmonary bypass model--a pilot study." Heart, Lung & Circulation 23, no. 10 (October 2014): 981-984. Full Text
  - Welsby, IJ, Phillips-Bute, B, Mathew, JP, Newman, MF, Becker, R, Rao, S, Milano, CA, and Stafford-Smith, M. "ABO blood group influences transfusion and survival after cardiac surgery." Journal of thrombosis and thrombolysis 38, no. 3 (October 2014): 402-408. Full Text
  - Castleberry, AW, Williams, JB, Daneshmand, MA, Honeycutt, E, Shaw, LK, Samad, Z, Lopes, RD, Alexander, JH, Mathew, JP, Velazquez, EJ, Milano, CA, and Smith, PK. "Surgical revascularization is associated with maximal survival in patients with ischemic mitral regurgitation: A 20-year experience." Circulation 129, no. 24 (June 17, 2014): 2547-2556. Full Text
  - Castleberry, AW, Williams, JB, Daneshmand, MA, Honeycutt, E, Shaw, LK, Samad, Z, Lopes, RD, Alexander, JH, Mathew, JP, Velazquez, EJ, Milano, CA, and Smith, PK. "Surgical revascularization is associated with maximal survival in patients with ischemic mitral regurgitation: a 20-year experience." Circulation 129, no. 24 (June 2014): 2547-2556. Full Text
  - Cobey, FC, Swaminathan, M, Phillips-Bute, B, Hyca, M, Glower, DD, Douglas, PS, Shaw, AD, Mathew, JP, and Mackensen, GB. "Quantitative assessment of mitral valve coaptation using three-dimensional transesophageal echocardiography." The Annals of thoracic surgery 97, no. 6 (June 2014): 1998-2004. Full Text
  - Fontes, MT, McDonagh, DL, Phillips-Bute, B, Welsby, IJ, Podgoreanu, MV, Fontes, ML, Stafford-Smith, M, Newman, MF, Mathew, JP, and Neurologic Outcome Research Group (NORG) of the Duke Heart Center, . "Arterial hyperoxia during cardiopulmonary bypass and postoperative cognitive dysfunction." J Cardiothorac Vasc Anesth 28, no. 3 (June 2014): 462-466. Full Text Link to Item
  - Aronson, S, Mathew, JP, Cheung, AT, Shore-Lesserson, L, Troianos, CA, and Reeves, S. "The rationale and development of an adult cardiac anesthesia module to supplement the society of thoracic surgeons national database: using data to drive quality." Anesthesia and Analgesia 118, no. 5 (May 2014): 925-932. (Review) Full Text
  - McDonagh, DL, Berger, M, Mathew, JP, Graffagnino, C, Milano, CA, and Newman, MF. "Neurological complications of cardiac surgery." The Lancet. Neurology 13, no. 5 (May 2014): 490-502. (Review) Full Text
  - Berger, M, Nadler, J, and Mathew, JP. "Preventing delirium after cardiothoracic surgery: provocative but preliminary evidence for bispectral index monitoring." Anesthesia and Analgesia 118, no. 4 (April 2014): 706-707. Full Text
  - Kertai, MD, Esper, SA, Akushevich, I, Voora, D, Ginsburg, GS, Stafford-Smith, M, Grichnik, K, Newman, MF, Fontes, ML, Smith, P, Podgoreanu, MV, Mathew, JP, and Cardiothoracic Anesthesia Research Endeavors (CARE) Group, . "Preoperative CYP2D6 metabolism-dependent β-blocker use and mortality after coronary artery bypass grafting surgery." The Journal of thoracic and cardiovascular surgery 147, no. 4 (April 2014): 1368-1375.e3. Full Text Open Access Copy
  - Yan, TD, Tian, DH, LeMaire, SA, Hughes, GC, Chen, EP, Misfeld, M, Griepp, RB, Kazui, T, Bannon, PG, Coselli, JS, Elefteriades, JA, Kouchoukos, NT, Underwood, MJ, Mathew, JP, Mohr, F-W, Oo, A, Sundt, TM, Bavaria, JE, Di Bartolomeo, R, Di Eusanio, M, Trimarchi, S, and International Aortic Arch Surgery Study Group, . "Standardizing clinical end points in aortic arch surgery: a consensus statement from the International Aortic Arch Surgery Study Group." Circulation 129, no. 15 (April 2014): 1610-1616. Full Text
  - Zeng, X, Nunes, MCP, Dent, J, Gillam, L, Mathew, JP, Gammie, JS, Ascheim, DD, Moquete, E, and Hung, J. "Asymmetric versus symmetric tethering patterns in ischemic mitral regurgitation: geometric differences from three-dimensional transesophageal echocardiography." Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 27, no. 4 (April 2014): 367-375. Full Text
  - Mathew, JP, Laskowitz, DT, and Newman, MF. "Response to letter regarding article, "Intraoperative magnesium administration does not improve neurocognitive function after cardiac surgery"." Stroke 45, no. 3 (March 2014): e45-. (Letter) Full Text
  - Sickeler, R, Phillips-Bute, B, Kertai, MD, Schroder, J, Mathew, JP, Swaminathan, M, and Stafford-Smith, M. "The risk of acute kidney injury with co-occurrence of anemia and hypotension during cardiopulmonary bypass relative to anemia alone." Ann Thorac Surg 97, no. 3 (March 2014): 865-871. Full Text Link to Item
  - Sickeler, R, Phillips-Bute, B, Kertai, MD, Schroder, J, Mathew, JP, Swaminathan, M, and Stafford-Smith, M. "The risk of acute kidney injury with co-occurrence of anemia and hypotension during cardiopulmonary bypass relative to anemia alone." Annals of Thoracic Surgery 97, no. 3 (March 1, 2014): 865-871. Full Text
  - "Preoperative CYP2D6 metabolism-dependent β-blocker use and mortality after coronary artery bypass grafting surgery." Journal of Thoracic and Cardiovascular Surgery 147, no. 4 (January 1, 2014). Full Text
  - "Effects of deep hypothermic circulatory arrest on the blood brain barrier in a cardiopulmonary bypass model - a pilot study." Heart Lung and Circulation 23, no. 10 (January 1, 2014): 981-984. Full Text
  - Cobey, FC, Swaminathan, M, Phillips-Bute, B, Hyca, M, Glower, DD, Douglas, PS, Shaw, AD, Mathew, JP, and Mackensen, GB. "Quantitative assessment of mitral valve coaptation using three-dimensional transesophageal echocardiography." Annals of Thoracic Surgery 97, no. 6 (January 1, 2014): 1998-2004. Full Text
  - Fontes, MT, McDonagh, DL, Phillips-Bute, B, Welsby, IJ, Podgoreanu, MV, Fontes, ML, Stafford-Smith, M, Newman, MF, and Mathew, JP. "Arterial hyperoxia during cardiopulmonary bypass and postoperative cognitive dysfunction." Journal of Cardiothoracic and Vascular Anesthesia 28, no. 3 (January 1, 2014): 462-466. Full Text
  - Mathew, JP, Laskowitz, DT, and Newman, MF. "Response to letter regarding article, "Intraoperative magnesium administration does not improve neurocognitive function after cardiac surgery"." Stroke; a Journal of Cerebral Circulation 45, no. 3 (January 1, 2014). Full Text
  - McDonagh, DL, Berger, M, Mathew, JP, Graffagnino, C, Milano, CA, and Newman, MF. "Neurological complications of cardiac surgery." The Lancet Neurology 13, no. 5 (January 1, 2014): 490-502. (Review) Full Text
  - Sickeler, R, Phillips-Bute, B, Kertai, MD, Schroder, J, Mathew, JP, Swaminathan, M, and Stafford-Smith, M. "The risk of acute kidney injury with co-occurrence of anemia and hypotension during cardiopulmonary bypass relative to anemia alone." Annals of Thoracic Surgery 97, no. 3 (2014): 865-871.
  - Welsby, IJ, Phillips-Bute, B, Mathew, JP, Newman, MF, Becker, R, Rao, S, Milano, CA, and Stafford-Smith, M. "ABO blood group influences transfusion and survival after cardiac surgery." Journal of Thrombosis and Thrombolysis 38, no. 3 (January 1, 2014): 402-408. Full Text
  - Zeng, X, Nunes, MCP, Dent, J, Gillam, L, Mathew, JP, Gammie, JS, Ascheim, DD, Moquete, E, and Hung, J. "Asymmetric versus symmetric tethering patterns in ischemic mitral regurgitation: Geometric differences from three-dimensional transesophageal echocardiography." Journal of the American Society of Echocardiography 27, no. 4 (January 1, 2014): 367-375. Full Text
  - Browndyke, JN, and Mathew, JP. "Neurological injury after transcatheter aortic valve implantation: are the trees falling silently or is our hearing impaired?." Circ Cardiovasc Interv 6, no. 6 (December 2013): 599-601. Full Text Open Access Copy Link to Item
  - Browndyke, JN, and Mathew, JP. "Neurological Injury After Transcatheter Aortic Valve Implantation Are the Trees Falling Silently or Is Our Hearing Impaired?." CIRCULATION-CARDIOVASCULAR INTERVENTIONS 6, no. 6 (December 2013): 599-601. Full Text Link to Item
  - Mathew, JP, White, WD, Schinderle, DB, Podgoreanu, MV, Berger, M, Milano, CA, Laskowitz, DT, Stafford-Smith, M, Blumenthal, JA, Newman, MF, and Neurologic Outcome Research Group (NORG) of The Duke Heart Center, . "Intraoperative magnesium administration does not improve neurocognitive function after cardiac surgery." Stroke 44, no. 12 (December 2013): 3407-3413. Full Text
  - Piccini, JP, Zhao, Y, Steinberg, BA, He, X, Mathew, JP, Fullerton, DA, Hegland, DD, Hernandez, AF, Mills, RM, Klaskala, W, and Peterson, ED. "Comparative effectiveness of pharmacotherapies for prevention of atrial fibrillation following coronary artery bypass surgery." The American Journal of Cardiology 112, no. 7 (October 2013): 954-960. Full Text
  - Klinger, RY, James, OG, Wong, TZ, Newman, MF, Doraiswamy, PM, and Mathew, JP. "Cortical β-amyloid levels and neurocognitive performance after cardiac surgery. (Published online)" BMJ Open 3, no. 9 (September 20, 2013): e003669-. Full Text Open Access Copy Link to Item
  - Newman, MF, Mathew, JP, and Aronson, S. "The evolution of anesthesiology and perioperative medicine." Anesthesiology 118, no. 5 (May 2013): 1005-1007. Full Text Link to Item
  - Bartels, K, Daneshmand, MA, Mathew, JP, Glower, DD, Swaminathan, M, and Nicoara, A. "Delayed postmyectomy ventricular septal defect." J Cardiothorac Vasc Anesth 27, no. 2 (April 2013): 381-384. Full Text Link to Item
  - Englum, BR, Andersen, ND, Husain, AM, Mathew, JP, and Hughes, GC. "Degree of hypothermia in aortic arch surgery - optimal temperature for cerebral and spinal protection: deep hypothermia remains the gold standard in the absence of randomized data." Annals of Cardiothoracic Surgery 2, no. 2 (March 2013): 184-193. Full Text
  - Balajonda, N, Bisanar, TL, Mathew, JP, Pang, H, and Voils, CI. "Determinants of a subject's decision to participate in clinical anesthesia research." Anesth Analg 116, no. 2 (February 2013): 448-454. Full Text Link to Item
  - Bartels, K, McDonagh, DL, Newman, MF, and Mathew, JP. "Neurocognitive outcomes after cardiac surgery." Current Opinion in Anaesthesiology 26, no. 1 (February 2013): 91-97. (Review) Full Text
  - Fontes, MT, Swift, RC, Phillips-Bute, B, Podgoreanu, MV, Stafford-Smith, M, Newman, MF, Mathew, JP, and Neurologic Outcome Research Group of the Duke Heart Center, . "Predictors of cognitive recovery after cardiac surgery." Anesthesia and Analgesia 116, no. 2 (February 2013): 435-442. Full Text
  - Aronson, S, Phillips-Bute, B, Stafford-Smith, M, Fontes, M, Gaca, J, Mathew, JP, and Newman, MF. "The association of postcardiac surgery acute kidney injury with intraoperative systolic blood pressure hypotension." Anesthesiol Res Pract 2013 (2013): 174091-. Full Text Open Access Copy Link to Item
  - Balajonda, N, Bisanar, TL, Mathew, JP, Pang, H, and Voils, CI. "Determinants of a subject's decision to participate in clinical anesthesia research." Anesthesia and Analgesia 116, no. 2 (2013): 448-454. Full Text
  - Fontes, MT, Swift, RC, Phillips-Bute, B, Podgoreanu, MV, Stafford-Smith, M, Newman, MF, and Mathew, JP. "Predictors of cognitive recovery after cardiac surgery." Anesthesia and Analgesia 116, no. 2 (2013): 435-442. Full Text
  - Piccini, JP, Zhao, Y, Steinberg, BA, He, X, Mathew, JP, Fullerton, DA, Hegland, DD, Hernandez, AF, Mills, RM, Klaskala, W, and Peterson, ED. "Comparative effectiveness of pharmacotherapies for prevention of atrial fibrillation following coronary artery bypass surgery." American Journal of Cardiology 112, no. 7 (2013): 954-960. Full Text
  - Hoffman, BM, Blumenthal, JA, Carney, RC, O'Hayer, CVF, Freedland, K, Smith, PJ, Babyak, MA, Davis, RD, Mathew, JP, Martinu, T, and Palmer, S. "Changes in neurocognitive functioning following lung transplantation." Am J Transplant 12, no. 9 (September 2012): 2519-2525. Full Text Link to Item
  - Perrault, LP, Moskowitz, AJ, Kron, IL, Acker, MA, Miller, MA, Horvath, KA, Thourani, VH, Argenziano, M, D'Alessandro, DA, Blackstone, EH, Moy, CS, Mathew, JP, Hung, J, Gardner, TJ, and Parides, MK. "Optimal surgical management of severe ischemic mitral regurgitation: to repair or to replace?." The Journal of Thoracic and Cardiovascular Surgery 143, no. 6 (June 2012): 1396-1403. Full Text
  - Marcucci, CE, Samad, Z, Rivera, J, Adams, DB, Philips-Bute, BG, Mahajan, A, Douglas, PS, Aronson, S, Mackensen, GB, Podgoreanu, MV, Mathew, JP, and Swaminathan, M. "A comparative evaluation of transesophageal and transthoracic echocardiography for measurement of left ventricular systolic strain using speckle tracking." J Cardiothorac Vasc Anesth 26, no. 1 (February 2012): 17-25. Full Text Link to Item
  - Drenger, B, Fontes, ML, Miao, Y, Mathew, JP, Gozal, Y, Aronson, S, Dietzel, C, and Mangano, DT. "Patterns of use of perioperative angiotensin-converting enzyme inhibitors in coronary artery bypass graft surgery with cardiopulmonary bypass: Effects on in-hospital morbidity and mortality." Circulation 126, no. 3 (2012): 261-269. Full Text
  - Lobato, RL, White, WD, Mathew, JP, Newman, MF, Smith, PK, McCants, CB, Alexander, JH, Podgoreanu, MV, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "Thrombomodulin gene variants are associated with increased mortality after coronary artery bypass surgery in replicated analyses." Circulation 124, no. 11 Suppl (September 2011): S143-S148. Full Text
  - Qing, M, Shim, J-K, Grocott, HP, Sheng, H, Mathew, JP, and Mackensen, GB. "The effect of blood pressure on cerebral outcome in a rat model of cerebral air embolism during cardiopulmonary bypass." J Thorac Cardiovasc Surg 142, no. 2 (August 2011): 424-429. Full Text Link to Item
  - McDonagh, DL, and Mathew, JP. "Perioperative stroke: where do we go from here?." Anesthesiology 114, no. 6 (June 2011): 1263-1264. Full Text Link to Item
  - Swaminathan, M, Nicoara, A, Phillips-Bute, BG, Aeschlimann, N, Milano, CA, Mackensen, GB, Podgoreanu, MV, Velazquez, EJ, Stafford-Smith, M, Mathew, JP, and Cardiothoracic Anesthesia Research Endeavors (CARE) Group, . "Utility of a simple algorithm to grade diastolic dysfunction and predict outcome after coronary artery bypass graft surgery." Ann Thorac Surg 91, no. 6 (June 2011): 1844-1850. Full Text Link to Item
  - Hsu, Y-W, Somma, J, Newman, MF, and Mathew, JP. "Population pharmacokinetics of lidocaine administered during and after cardiac surgery." Journal of Cardiothoracic and Vascular Anesthesia 25, no. 6 (2011): 931-936. Full Text
  - Welsby, IJ, Troughton, M, Phillips-Bute, B, Ramsey, R, Campbell, ML, Bandarenko, N, Mathew, JP, Stafford-Smith, M, and Cardiothoracic Anesthesiology Research Endeavors, . "The relationship of plasma transfusion from female and male donors with outcome after cardiac surgery." J Thorac Cardiovasc Surg 140, no. 6 (December 2010): 1353-1360. Full Text Link to Item
  - Lobato, RL, White, WD, Mathew, JP, Newman, MF, Alexander, JH, and Podgoreanu, MV. "Thrombomodulin Variants are Associated with Increased Mortality following CABG Surgery in Replicated Analyses." CIRCULATION 122, no. 21 (November 23, 2010). Link to Item
  - McDonagh, DL, Mathew, JP, White, WD, and Newman, MF. "In reply." Anesthesiology 113, no. 5 (November 1, 2010): 1248-1250. (Letter) Full Text
  - McDonagh, DL, Mathew, JP, White, WD, and Newman, MF. "Postoperative Cognitive Decline: The Unsubstantiated Phenotype." Anesthesiology 113, no. 5 (November 2010): 1248-1250. Full Text
  - Welsby, IJ, Lockhart, E, Phillips-Bute, B, Campbell, ML, Mathew, JP, Newman, MF, Peterson, E, Milano, CA, Mark Stafford-Smith for members of the Cardiothoracic Anesthesiology Research Endeavors (C.A.R.E.), Department of Anesthesiology, and Duke University Medical Center, . "Storage age of transfused platelets and outcomes after cardiac surgery." Transfusion 50, no. 11 (November 2010): 2311-2317. Full Text
  - Hudson, CCC, Welsby, IJ, Phillips-Bute, B, Mathew, JP, Lutz, A, Chad Hughes, G, Stafford-Smith, M, and Cardiothoracic Anesthesiology Research Endeavors (C.A.R.E.) Group, . "Glycosylated hemoglobin levels and outcome in non-diabetic cardiac surgery patients." Can J Anaesth 57, no. 6 (June 2010): 565-572. Full Text Link to Item
  - Lombard, FW, and Mathew, JP. "Neurocognitive dysfunction following cardiac surgery." Semin Cardiothorac Vasc Anesth 14, no. 2 (June 2010): 102-110. (Review) Full Text Link to Item
  - Mackensen, GB, Swaminathan, M, and Mathew, JP. "PRO editorial: PRO: three-dimensional transesophageal echocardiography is a major advance for intraoperative clinical management of patients undergoing cardiac surgery." Anesth Analg 110, no. 6 (June 1, 2010): 1574-1578. Full Text Link to Item
  - Welsby, IJ, Podgoreanu, MV, Phillips-Bute, B, Morris, R, Mathew, JP, Smith, PK, Newman, MF, Schwinn, DA, Stafford-Smith, M, and Perioperative Genetics and Safety Outcomes Study Investigative Team, . "Association of the 98T ELAM-1 polymorphism with increased bleeding after cardiac surgery." J Cardiothorac Vasc Anesth 24, no. 3 (June 2010): 427-433. Full Text Link to Item
  - Swaminathan, M, Hudson, CCC, Phillips-Bute, BG, Patel, UD, Mathew, JP, Newman, MF, Milano, CA, Shaw, AD, and Stafford-Smith, M. "Impact of early renal recovery on survival after cardiac surgery-associated acute kidney injury." Ann Thorac Surg 89, no. 4 (April 2010): 1098-1104. Full Text Link to Item
  - Nikolov, NM, Fontes, ML, White, WD, Aronson, S, Bar-Yosef, S, Gaca, JG, Podgoreanu, MV, Stafford-Smith, M, Newman, MF, and Mathew, JP. "Pulse pressure and long-term survival after coronary artery bypass graft surgery." Anesthesia and Analgesia 110, no. 2 (February 2010): 335-340. Full Text
  - Swaminathan, M, Phillips-Bute, BG, Patel, UD, Shaw, AD, Stafford-Smith, M, Douglas, PS, Archer, LE, Smith, PK, and Mathew, JP. "Increasing healthcare resource utilization after coronary artery bypass graft surgery in the United States." Circulation. Cardiovascular Quality and Outcomes 2, no. 4 (July 2009): 305-312. Full Text
  - Turer, AT, Stevens, RD, Bain, JR, Muehlbauer, MJ, van der Westhuizen, J, Mathew, JP, Schwinn, DA, Glower, DD, Newgard, CB, and Podgoreanu, MV. "Metabolomic profiling reveals distinct patterns of myocardial substrate use in humans with coronary artery disease or left ventricular dysfunction during surgical ischemia/reperfusion." Circulation 119, no. 13 (April 2009): 1736-1746. Full Text
  - Mathew, JP, Mackensen, GB, Phillips-Bute, B, Grocott, HP, Glower, DD, Laskowitz, DT, Blumenthal, JA, Newman, MF, and Neurologic Outcome Research Group (NORG) of the Duke Heart Center, . "Randomized, double-blinded, placebo controlled study of neuroprotection with lidocaine in cardiac surgery." Stroke 40, no. 3 (March 2009): 880-887. Full Text
  - Jungwirth, B, Adams, DB, Mathew, JP, Swaminathan, M, Glower, DD, and Mackensen, GB. "Mitral valve prolapse and systolic anterior motion illustrated by real time three-dimensional transesophageal echocardiography." Anesth Analg 107, no. 6 (December 2008): 1822-1824. Full Text Link to Item
  - Mulvagh, SL, Rakowski, H, Vannan, MA, Abdelmoneim, SS, Becher, H, Bierig, SM, Burns, PN, Castello, R, Coon, PD, Hagen, ME, Jollis, JG, Kimball, TR, Kitzman, DW, Kronzon, I, Labovitz, AJ, Lang, RM, Mathew, J, Moir, WS, Nagueh, SF, Pearlman, AS, Perez, JE, Porter, TR, Rosenbloom, J, Strachan, GM, Thanigaraj, S, Wei, K, Woo, A, Yu, EHC, Zoghbi, WA, and American Society of Echocardiography, . "American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography." Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography 21, no. 11 (November 2008): 1179-1281. Full Text
  - Phillips-Bute, B, Mathew, JP, Blumenthal, JA, Morris, RW, Podgoreanu, MV, Smith, M, Stafford-Smith, M, Grocott, HP, Schwinn, DA, Newman, MF, and Perioperative Genetics and Safety Outcomes Investigative Team, . "Relationship of genetic variability and depressive symptoms to adverse events after coronary artery bypass graft surgery." Psychosomatic Medicine 70, no. 9 (November 2008): 953-959. Full Text
  - Phillips-Bute, B, and Mathew, JP. "Cognitive outcomes analyses: two steps forward, one step back?." J Cardiothorac Vasc Anesth 22, no. 4 (August 2008): 513-514. Full Text Link to Item
  - Martinelli, SM, Mitchell, JD, McCann, RL, Podgoreanu, MV, Mathew, JP, and Swaminathan, M. "Intraoperative transesophageal echocardiography diagnosis of residual tumor fragment after surgical removal of renal cell carcinoma." Anesth Analg 106, no. 6 (June 2008): 1633-1635. Full Text Link to Item
  - Glas, KE, Swaminathan, M, Reeves, ST, Shanewise, JS, Rubenson, D, Smith, PK, Mathew, JP, Shernan, SK, Council for Intraoperative Echocardiography of the American Society of Echocardiography, , Society of Cardiovascular Anesthesiologists, , and Society of Thoracic Surgeons, . "Guidelines for the performance of a comprehensive intraoperative epiaortic ultrasonographic examination: recommendations of the American Society of Echocardiography and the Society of Cardiovascular Anesthesiologists; endorsed by the Society of Thoracic Surgeons." Anesth Analg 106, no. 5 (May 2008): 1376-1384. Full Text Link to Item
  - Shaw, AD, Stafford-Smith, M, White, WD, Phillips-Bute, B, Swaminathan, M, Milano, C, Welsby, IJ, Aronson, S, Mathew, JP, Peterson, ED, and Newman, MF. "The effect of aprotinin on outcome after coronary-artery bypass grafting." The New England Journal of Medicine 358, no. 8 (February 2008): 784-793. Full Text
  - Fontes, ML, Aronson, S, Mathew, JP, Miao, Y, Drenger, B, Barash, PG, and Mangano, DT. "Pulse pressure and risk of adverse outcome in coronary bypass surgery." Anesthesia and Analgesia 107, no. 4 (2008): 1122-1129. Full Text
  - Nicoara, A, Mackensen, GB, Podgoreanu, MV, Milano, CA, Mathew, JP, and Swaminathan, M. "Malpositioned left ventricular assist device cannula: diagnosis and management with transesophageal echocardiography guidance." Anesth Analg 105, no. 6 (December 2007): 1574-1576. Full Text Link to Item
  - Welsby, IJ, Jones, R, Pylman, J, Mark, JB, Brudney, CS, Phillips-Bute, B, Mathew, JP, Campbell, ML, Stafford-Smith, M, Cardiothoracic Anesthesiology Research Endeavours (C.A.R.E.), Department of Anesthesiology, and Duke University Medical Center, . "ABO blood group and bleeding after coronary artery bypass graft surgery." Blood Coagul Fibrinolysis 18, no. 8 (December 2007): 781-785. Full Text Link to Item
  - Glas, KE, Swaminathan, M, Reeves, ST, Shanewise, JS, Rubenson, D, Smith, PK, Mathew, JP, Shernan, SK, Council for Intraoperative Echocardiography of the American Society of Echocardiography, , and Society of Cardiovascular Anesthesiologists, . "Guidelines for the performance of a comprehensive intraoperative epiaortic ultrasonographic examination: recommendations of the American Society of Echocardiography and the Society of Cardiovascular Anesthesiologists; endorsed by the Society of Thoracic Surgeons." J Am Soc Echocardiogr 20, no. 11 (November 2007): 1227-1235. Full Text Link to Item
  - Puskas, F, Grocott, HP, White, WD, Mathew, JP, Newman, MF, and Bar-Yosef, S. "Intraoperative hyperglycemia and cognitive decline after CABG." Ann Thorac Surg 84, no. 5 (November 2007): 1467-1473. Full Text Link to Item
  - Swaminathan, M, Morris, RW, De Meyts, DD, Podgoreanu, MV, Jollis, JG, Grocott, HP, Milano, CA, Newman, MF, and Mathew, JP. "Deterioration of regional wall motion immediately after coronary artery bypass graft surgery is associated with long-term major adverse cardiac events." Anesthesiology 107, no. 5 (November 2007): 739-745. Full Text Link to Item
  - Mathew, JP, Mackensen, GB, Phillips-Bute, B, Stafford-Smith, M, Podgoreanu, MV, Grocott, HP, Hill, SE, Smith, PK, Blumenthal, JA, Reves, JG, Newman, MF, and Neurologic Outcome Research Group (NORG) of the Duke Heart Center, . "Effects of extreme hemodilution during cardiac surgery on cognitive function in the elderly." Anesthesiology 107, no. 4 (October 2007): 577-584. Full Text
  - Swaminathan, M, Grocott, HP, Mackensen, GB, Podgoreanu, MV, Glower, DD, and Mathew, JP. "The "sandblasting" effect of aortic cannula on arch atheroma during cardiopulmonary bypass." Anesth Analg 104, no. 6 (June 2007): 1350-1351. Full Text Link to Item
  - Mathew, JP, Podgoreanu, MV, Grocott, HP, White, WD, Morris, RW, Stafford-Smith, M, Mackensen, GB, Rinder, CS, Blumenthal, JA, Schwinn, DA, Newman, MF, and PEGASUS Investigative Team, . "Genetic variants in P-selectin and C-reactive protein influence susceptibility to cognitive decline after cardiac surgery." Journal of the American College of Cardiology 49, no. 19 (May 2007): 1934-1942. Full Text
  - Swaminathan, M, Mackensen, GB, Podgoreanu, MV, McCann, RL, Mathew, JP, and Hughes, GC. "Spontaneous echocardiographic contrast indicating successful endoleak management." Anesth Analg 104, no. 5 (May 2007): 1037-1039. Full Text Link to Item
  - Mitchell, JD, Grocott, HP, Phillips-Bute, B, Mathew, JP, Newman, MF, and Bar-Yosef, S. "Cytokine secretion after cardiac surgery and its relationship to postoperative fever." Cytokine 38, no. 1 (April 2007): 37-42. Full Text Link to Item
  - Bar-Yosef, S, Cozart, HB, Phillips-Bute, B, Mathew, JP, and Grocott, HP. "Preoperative low molecular weight heparin reduces heparin responsiveness during cardiac surgery." Can J Anaesth 54, no. 2 (February 2007): 107-113. Full Text Link to Item
  - Doraiswamy, PM, Babyak, MA, Hennig, T, Trivedi, R, White, WD, Mathew, JP, Newman, MF, and Blumenthal, JA. "Donepezil for cognitive decline following coronary artery bypass surgery: a pilot randomized controlled trial." Psychopharmacology Bulletin 40, no. 2 (January 2007): 54-62.
  - Reeves, ST, Glas, KE, Eltzschig, H, Mathew, JP, Rubenson, DS, Hartman, GS, and Shernan, SK. "Guidelines for performing a comprehensive epicardial echocardiography examination: Recommendations of the american society of echocardiography and the society of cardiovascular anesthesiologists." Anesthesia and Analgesia 105, no. 1 (2007): 22-28. Full Text
  - Reeves, ST, Glas, KE, Eltzschig, H, Mathew, JP, Rubenson, DS, Hartman, GS, and Shernan, SK. "Guidelines for Performing a Comprehensive Epicardial Echocardiography Examination: Recommendations of the American Society of Echocardiography and the Society of Cardiovascular Anesthesiologists." Journal of the American Society of Echocardiography 20, no. 4 (2007): 427-437. Full Text
  - Vaitkeviciute, I, Mathew, JP, and Barash, PG. "Mitral valve replacement." Decision Making in Anesthesiology (2007): 292-295. Full Text
  - Mathew, JP, Glas, K, Troianos, CA, Sears-Rogan, P, Savage, R, Shanewise, J, Kisslo, J, Aronson, S, Shernan, S, American Society of Echocardiography, , and Society of Cardiovascular Anesthesiologists, . "American Society of Echocardiography/Society of Cardiovascular Anesthesiologists recommendations and guidelines for continuous quality improvement in perioperative echocardiography." J Am Soc Echocardiogr 19, no. 11 (November 2006): 1303-1313. Full Text Link to Item
  - Newman, MF, Mathew, JP, Grocott, HP, Mackensen, GB, Monk, T, Welsh-Bohmer, KA, Blumenthal, JA, Laskowitz, DT, and Mark, DB. "Central nervous system injury associated with cardiac surgery." Lancet (London, England) 368, no. 9536 (August 2006): 694-703. (Review) Full Text
  - Izrailtyan, I, Clark, J, Swaminathan, M, Podgoreanu, MV, Mackensen, B, Davis, RD, and Mathew, JP. "Case report: optimizing intraoperative detection of pulmonary embolism using contrast-enhanced echocardiography." Can J Anaesth 53, no. 7 (July 2006): 711-715. Full Text Link to Item
  - Izrailtyan, I, Clark, J, Swaminathan, M, Podgoreanu, MV, Mackensen, B, Davis, RD, and Mathew, JP. "Case report: Optimizing intraoperative detection of pulmonary embolism echocardiography." CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE 53, no. 7 (July 2006): 711-715. Full Text Link to Item
  - Podgoreanu, MV, White, WD, Morris, RW, Mathew, JP, Stafford-Smith, M, Welsby, IJ, Grocott, HP, Milano, CA, Newman, MF, Schwinn, DA, and Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team, . "Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery." Circulation 114, no. 1 Suppl (July 2006): I275-I281. Full Text
  - Mathew, JP, Rinder, HM, Smith, BR, Newman, MF, and Rinder, CS. "Transcerebral platelet activation after aortic cross-clamp release is linked to neurocognitive decline." The Annals of Thoracic Surgery 81, no. 5 (May 2006): 1644-1649. Full Text
  - Phillips-Bute, B, Mathew, JP, Blumenthal, JA, Grocott, HP, Laskowitz, DT, Jones, RH, Mark, DB, and Newman, MF. "Association of neurocognitive function and quality of life 1 year after coronary artery bypass graft (CABG) surgery." Psychosomatic Medicine 68, no. 3 (May 2006): 369-375. Full Text
  - Mathew, JP, Glas, K, Troianos, CA, Sears-Rogan, P, Savage, R, Shanewise, J, Kisslo, J, Aronson, S, and Shernan, S. "ASE/SCA recommendations and guidelines for continuous quality improvement in perioperative echocardiography." Anesthesia and Analgesia 103, no. 6 (2006): 1416-1425. Full Text
  - Podgoreanu, MV, and Mathew, JP. "Prophylaxis against postoperative atrial fibrillation: current progress and future directions." JAMA 294, no. 24 (December 28, 2005): 3140-3142. Full Text Link to Item
  - Grocott, HP, White, WD, Morris, RW, Podgoreanu, MV, Mathew, JP, Nielsen, DM, Schwinn, DA, Newman, MF, and Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team, . "Genetic polymorphisms and the risk of stroke after cardiac surgery." Stroke 36, no. 9 (September 2005): 1854-1858. Full Text Link to Item
  - Podgoreanu, MV, Michelotti, GA, Sato, Y, Smith, MP, Lin, S, Morris, RW, Grocott, HP, Mathew, JP, and Schwinn, DA. "Differential cardiac gene expression during cardiopulmonary bypass: ischemia-independent upregulation of proinflammatory genes." J Thorac Cardiovasc Surg 130, no. 2 (August 2005): 330-339. Full Text Link to Item
  - Schroder, JN, Williams, ML, Hata, JA, Muhlbaier, LH, Swaminathan, M, Mathew, JP, Glower, DD, O'Connor, CM, Smith, PK, and Milano, CA. "Impact of mitral valve regurgitation evaluated by intraoperative transesophageal echocardiography on long-term outcomes after coronary artery bypass grafting." Circulation 112, no. 9 Suppl (August 2005): I293-I298. Full Text
  - Fontes, ML, Mathew, JP, Rinder, HM, Zelterman, D, Smith, BR, Rinder, CS, and Multicenter Study of Perioperative Ischemia (McSPI) Research Group, . "Atrial fibrillation after cardiac surgery/cardiopulmonary bypass is associated with monocyte activation." Anesthesia and Analgesia 101, no. 1 (July 2005): 17-23. Full Text
  - Corkey, WB, Phillips-Bute, B, Baudet, B, Mathew, JP, Newman, MF, and Grocott, HP. "Brief report: The declining incidence of cerebral hyperthermia during cardiac surgery: a seven-year experience in 6,334 patients." Can J Anaesth 52, no. 6 (June 2005): 626-629. Link to Item
  - Mathew, JP, Grocott, HP, McCurdy, JR, Ti, LK, Davis, RD, Laskowitz, DT, Podgoreanu, MV, Swaminathan, M, Lynch, J, Stafford-Smith, M, White, WD, and Newman, MF. "Preoperative statin therapy does not reduce cognitive dysfunction after cardiopulmonary bypass." Journal of Cardiothoracic and Vascular Anesthesia 19, no. 3 (June 2005): 294-299. Full Text
  - Welsby, IJ, Podgoreanu, MV, Phillips-Bute, B, Mathew, JP, Smith, PK, Newman, MF, Schwinn, DA, Stafford-Smith, M, and Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team, . "Genetic factors contribute to bleeding after cardiac surgery." J Thromb Haemost 3, no. 6 (June 2005): 1206-1212. Full Text Link to Item
  - Stafford-Smith, M, Podgoreanu, M, Swaminathan, M, Phillips-Bute, B, Mathew, JP, Hauser, EH, Winn, MP, Milano, C, Nielsen, DM, Smith, M, Morris, R, Newman, MF, Schwinn, DA, and Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team, . "Association of genetic polymorphisms with risk of renal injury after coronary bypass graft surgery." Am J Kidney Dis 45, no. 3 (March 2005): 519-530. Full Text Link to Item
  - Bar-Yosef, S, Anders, M, Mackensen, GB, Ti, LK, Mathew, JP, Phillips-Bute, B, Messier, RH, Grocott, HP, and Neurological Outcome Research Group and CARE Investigators of the Duke Heart Center, . "Aortic atheroma burden and cognitive dysfunction after coronary artery bypass graft surgery." Ann Thorac Surg 78, no. 5 (November 2004): 1556-1562. Full Text Link to Item
  - Mathew, JP, Shernan, SK, White, WD, Fitch, JCK, Chen, JC, Bell, L, and Newman, MF. "Preliminary report of the effects of complement suppression with pexelizumab on neurocognitive decline after coronary artery bypass graft surgery." Stroke 35, no. 10 (October 2004): 2335-2339. Full Text Link to Item
  - Bar-Yosef, S, Mathew, JP, Newman, MF, Landolfo, KP, Grocott, HP, Neurological Outcome Research Group, , and C A R E Investigators of the Duke Heart Center, . "Prevention of cerebral hyperthermia during cardiac surgery by limiting on-bypass rewarming in combination with post-bypass body surface warming: a feasibility study." Anesth Analg 99, no. 3 (September 2004): 641-646. Full Text Link to Item
  - MacKensen, GB, Swaminathan, M, Ti, LK, Grocott, HP, Phillips-Bute, BG, Mathew, JP, Newman, MF, Milano, CA, Stafford-Smith, M, Perioperative Outcomes Research Group, , and Cardiothoracic Anesthesiology Research Endeavors (C.A.R.E.) Investigators of the Duke Heart Center, . "Preliminary report on the interaction of apolipoprotein E polymorphism with aortic atherosclerosis and acute nephropathy after CABG." Ann Thorac Surg 78, no. 2 (August 2004): 520-526. Full Text Link to Item
  - McKinlay, KH, Schinderle, DB, Swaminathan, M, Podgoreanu, MV, Milano, CA, Messier, RH, El-Moalem, H, Newman, MF, Clements, FM, and Mathew, JP. "Predictors of inotrope use during separation from cardiopulmonary bypass." J Cardiothorac Vasc Anesth 18, no. 4 (August 2004): 404-408. Link to Item
  - Mathew, JP, Fontes, ML, and Mangano, DT. "Atrial fibrillation and risk of postoperative complications - Reply." JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 292, no. 1 (July 7, 2004): 41-42. Full Text Link to Item
  - Mathew, JP, Fontes, ML, Tudor, IC, Ramsay, J, Duke, P, Mazer, CD, Barash, PG, Hsu, PH, Mangano, DT, Investigators of the Ischemia Research and Education Foundation, , and Multicenter Study of Perioperative Ischemia Research Group, . "A multicenter risk index for atrial fibrillation after cardiac surgery." Jama 291, no. 14 (April 2004): 1720-1729. Full Text
  - Djaiani, G, Phillips-Bute, B, Podgoreanu, M, Messier, RH, Mathew, JP, Clements, F, and Newman, MF. "The association of patent foramen ovale and atrial fibrillation after coronary artery bypass graft surgery." Anesth Analg 98, no. 3 (March 2004): 585-589. Link to Item
  - Grocott, HP, Mathew, JP, Carver, EH, Phillips-Bute, B, Landolfo, KP, Newman, MF, and Duke Heart Center Neurologic Outcome Research Group, . "A randomized controlled trial of the Arctic Sun Temperature Management System versus conventional methods for preventing hypothermia during off-pump cardiac surgery." Anesthesia and Analgesia 98, no. 2 (February 2004): 298-302. Full Text
  - Auer, J, Weber, T, Eber, B, Mathew, JP, Fontes, ML, and Mangano, DT. "Atria fibrillation and risk of postoperative complications [4] (multiple letters)." Journal of the American Medical Association 292, no. 1 (2004): 41-42.
  - Swaminathan, M, Lineberger, CK, McCann, RL, and Mathew, JP. "The importance of intraoperative transesophageal echocardiography in endovascular repair of thoracic aortic aneurysms." Anesth Analg 97, no. 6 (December 2003): 1566-1572. Link to Item
  - Kilts, JD, Akazawa, T, El-Moalem, HE, Mathew, JP, Newman, MF, and Kwatra, MM. "Age increases expression and receptor-mediated activation of G alpha i in human atria." Journal of Cardiovascular Pharmacology 42, no. 5 (November 2003): 662-670. Full Text
  - Phillips Bute, B, Mathew, J, Blumenthal, JA, Welsh-Bohmer, K, White, WD, Mark, D, Landolfo, K, and Newman, MF. "Female gender is associated with impaired quality of life 1 year after coronary artery bypass surgery." Psychosom Med 65, no. 6 (November 2003): 944-951. Link to Item
  - Scarborough, JE, White, W, Derilus, FE, Mathew, JP, Newman, MF, Landolfo, KP, and Neurological Outcome Research Group, . "Combined use of off-pump techniques and a sutureless proximal aortic anastomotic device reduces cerebral microemboli generation during coronary artery bypass grafting." The Journal of Thoracic and Cardiovascular Surgery 126, no. 5 (November 2003): 1561-1567. Full Text
  - Koch, CG, Weng, Y-S, Zhou, SX, Savino, JS, Mathew, JP, Hsu, PH, Saidman, LJ, Mangano, DT, Ischemia Research and Education Foundation, , and Multicenter Study of Perioperative Ischemia Research Group, . "Prevalence of risk factors, and not gender per se, determines short- and long-term survival after coronary artery bypass surgery." J Cardiothorac Vasc Anesth 17, no. 5 (October 2003): 585-593. (Review) Link to Item
  - Swaminathan, M, Phillips-Bute, BG, and Mathew, JP. "An assessment of two different methods of left ventricular ejection time measurement by transesophageal echocardiography." Anesth Analg 97, no. 3 (September 2003): 642-647. Link to Item
  - Blumenthal, JA, Lett, HS, Babyak, MA, White, W, Smith, PK, Mark, DB, Jones, R, Mathew, JP, Newman, MF, and NORG Investigators, . "Depression as a risk factor for mortality after coronary artery bypass surgery." Lancet 362, no. 9384 (August 23, 2003): 604-609. Full Text Link to Item
  - Booth, JV, Phillips-Bute, B, McCants, CB, Podgoreanu, MV, Smith, PK, Mathew, JP, and Newman, MF. "Low serum magnesium level predicts major adverse cardiac events after coronary artery bypass graft surgery." Am Heart J 145, no. 6 (June 2003): 1108-1113. Full Text Link to Item
  - Podgoreanu, MV, Djaiani, GN, Davis, E, Phillips-Bute, B, and Mathew, JP. "Quantitative echocardiographic assessment of regional wall motion and left ventricular asynchrony with color kinesis in cardiac surgery patients." Anesth Analg 96, no. 5 (May 2003): 1294-1300. Link to Item
  - Stanley, TO, Grocott, HP, Phillips-Bute, B, Mathew, JP, Landolfo, KP, Newman, MF, Neurologic Outcome Research Group C.A.R.E, , and Investigators of the Duke Heart Center, . "Preliminary evaluation of the Arctic Sun temperature-controlling system during off-pump coronary artery bypass surgery." Ann Thorac Surg 75, no. 4 (April 2003): 1140-1144. Link to Item
  - Albahrani, MJ, Swaminathan, M, Phillips-Bute, B, Smith, PK, Newman, MF, Mathew, JP, and Stafford-Smith, M. "Postcardiac surgery complications: association of acute renal dysfunction and atrial fibrillation." Anesthesia and Analgesia 96, no. 3 (March 2003): 637-643. Full Text
  - Rinder, CS, Fontes, M, Mathew, JP, Rinder, HM, Smith, BR, and Multicenter Study of Perioperative Ischemia Research Group, . "Neutrophil CD11b upregulation during cardiopulmonary bypass is associated with postoperative renal injury." Ann Thorac Surg 75, no. 3 (March 2003): 899-905. Link to Item
  - Hagen, SA, Kondyra, AL, Grocott, HP, El-Moalem, H, Bainbridge, D, Mathew, JP, Newman, MF, Reves, JG, Schwinn, DA, and Kwatra, MM. "Cardiopulmonary bypass decreases G protein-coupled receptor kinase activity and expression in human peripheral blood mononuclear cells." Anesthesiology 98, no. 2 (February 2003): 343-348. Full Text
  - Mathew, JP, Grocott, HP, Phillips-Bute, B, Stafford-Smith, M, Laskowitz, DT, Rossignol, D, Blumenthal, JA, Newman, MF, Neurologic Outcome Research Group of the Duke Heart Center, , and Cardiothoracic Anesthesiology Research Endeavors Investigators of the Duke Heart Center, . "Lower endotoxin immunity predicts increased cognitive dysfunction in elderly patients after cardiac surgery." Stroke 34, no. 2 (February 2003): 508-513. Full Text
  - Mathew, JP. "Research in cardiovascular anesthesia: Preparing the subspecialty for a bright future." Current Opinion in Anaesthesiology 16, no. 1 (February 1, 2003): 1-2. Full Text
  - Scarborough, JE, White, W, Derilus, FE, Mathew, JP, Newman, MF, and Landolfo, KP. "Neurologic outcomes after coronary artery bypass grafting with and without cardiopulmonary bypass." Semin Thorac Cardiovasc Surg 15, no. 1 (January 2003): 52-62. (Review) Link to Item
  - Ti, LK, Mackensen, GB, Grocott, HP, Laskowitz, DT, Phillips-Bute, BG, Milano, CA, Hilton, AK, Newman, MF, Mathew, JP, and Neurologic Outcome Research Group, . "Apolipoprotein E4 increases aortic atheroma burden in cardiac surgical patients." The Journal of Thoracic and Cardiovascular Surgery 125, no. 1 (January 2003): 211-213. Full Text
  - Rinder, CS, Mathew, JP, Rinder, HM, Greg Howe, J, Fontes, M, Crouch, J, Pfau, S, Patel, P, Smith, BR, and Multicenter Study of Perioperative Ischemia Research Group, . "Platelet PlA2 polymorphism and platelet activation are associated with increased troponin I release after cardiopulmonary bypass." Anesthesiology 97, no. 5 (November 2002): 1118-1122. Link to Item
  - Djaiani, GN, McCreath, BJ, Ti, LK, Mackensen, BG, Podgoreanu, M, Phillips-Bute, B, and Mathew, JP. "Mitral flow propagation velocity identifies patients with abnormal diastolic function during coronary artery bypass graft surgery." Anesth Analg 95, no. 3 (September 2002): 524-530. Link to Item
  - Swaminathan, M, Debruijn, NP, Glower, DD, and Mathew, JP. "Unexpected transesophageal echocardiographic finding after septal myectomy." J Cardiothorac Vasc Anesth 16, no. 3 (June 2002): 384-385. Link to Item
  - Savino, JS, Ley, C, Boisvert, D, Friedman, A, Mathew, J, Koch, C, Starr, N, Mangano, CM, Herskowitz, A, Browner, WS, Mangano, DT, Multicenter Study of Perioperative Ischemia (McSPI) Research Group, , and Ischemia Research and Education Foundation (IREF), . "Practice pattern variability for myocardial revascularization: impact on resource use across 24 centers." J Cardiothorac Vasc Anesth 16, no. 2 (April 2002): 149-156. Link to Item
  - Grocott, HP, Mackensen, GB, Grigore, AM, Mathew, J, Reves, JG, Phillips-Bute, B, Smith, PK, Newman, MF, Neurologic Outcome Research Group (NORG), , and Cardiothoracic Anesthesiology Research Endeavors (CARE) Investigators' of the Duke Heart Center, . "Postoperative hyperthermia is associated with cognitive dysfunction after coronary artery bypass graft surgery." Stroke 33, no. 2 (February 2002): 537-541. Full Text
  - Mathew, JP, Fontes, ML, Garwood, S, Davis, E, White, WD, McCloskey, G, Fitch, JCK, Afifi, S, Lee, DL, Kraker, P, Rafferty, TD, Barash, PG, Gillam, L, and Prokop, E. "Transesophageal echocardiography interpretation: a comparative analysis between cardiac anesthesiologists and primary echocardiographers." Anesth Analg 94, no. 2 (February 2002): 302-309. Link to Item
  - Mathew, JP. "Intraoperative transesophageal echocardiography in the new millennium: still following the ‘dancing doughnut’?." Current Opinion in Anaesthesiology 15, no. 1 (February 2002): 1-2. Full Text
  - Stanley, TO, Mackensen, GB, Grocott, HP, White, WD, Blumenthal, JA, Laskowitz, DT, Landolfo, KP, Reves, JG, Mathew, JP, Newman, MF, Neurological Outcome Research Group, , and CARE Investigators of the Duke Heart Center, . "The impact of postoperative atrial fibrillation on neurocognitive outcome after coronary artery bypass graft surgery." Anesthesia and Analgesia 94, no. 2 (February 2002): 290-295. Full Text
  - Newman, MF, Grocott, HP, Mathew, JP, White, WD, Landolfo, K, Reves, JG, Laskowitz, DT, Mark, DB, Blumenthal, JA, and Neurologic Outcome Research Group and the Cardiothoracic Anesthesia Research Endeavors (CARE) Investigators of the Duke Heart Center, . "Report of the substudy assessing the impact of neurocognitive function on quality of life 5 years after cardiac surgery." Stroke 32, no. 12 (December 2001): 2874-2881. Full Text
  - Grigore, AM, Mathew, J, Grocott, HP, Reves, JG, Blumenthal, JA, White, WD, Smith, PK, Jones, RH, Kirchner, JL, Mark, DB, Newman, MF, Neurological Outcome Research Group, , and CARE Investigators of the Duke Heart Center. Cardiothoracic Anesthesia Research Endeavors, . "Prospective randomized trial of normothermic versus hypothermic cardiopulmonary bypass on cognitive function after coronary artery bypass graft surgery." Anesthesiology 95, no. 5 (November 2001): 1110-1119. Link to Item
  - Ti, LK, Mathew, JP, Mackensen, GB, Grocott, HP, White, WD, Reves, JG, and Newman, MF. "Effect of apolipoprotein E genotype on cerebral autoregulation during cardiopulmonary bypass." Stroke 32, no. 7 (July 2001): 1514-1519. Link to Item
  - Mathew, JP, Weatherwax, KJ, East, CJ, White, WD, and Reves, JG. "Bispectral analysis during cardiopulmonary bypass: the effect of hypothermia on the hypnotic state." J Clin Anesth 13, no. 4 (June 2001): 301-305. Link to Item
  - Mathew, JP, Rinder, CS, Howe, JG, Fontes, M, Crouch, J, Newman, MF, Phillips-Bute, B, and Smith, BR. "Platelet PlA2 polymorphism enhances risk of neurocognitive decline after cardiopulmonary bypass. Multicenter Study of Perioperative Ischemia (McSPI) Research Group." Ann Thorac Surg 71, no. 2 (February 2001): 663-666. Link to Item
  - Mathew, JP, Rinder, CS, Howe, JG, Fontes, M, Crouch, J, Newman, MF, Phillips-Bute, B, and Smith, BR. "Platelet p1^A2 polymorphism enhances risk of neurocognitive decline after cardiopulmonary bypass." Annals of Thoracic Surgery 71, no. 2 (January 1, 2001): 663-666. Full Text
  - Newman, MF, Booth, JV, Laskowitz, DT, Schwinn, DA, Grocott, HP, and Mathew, JP. "Genetic predictors of perioperative neurological and cognitive injury and recovery." Best Practice and Research: Clinical Anaesthesiology 15, no. 2 (January 1, 2001): 247-276. Full Text
  - Ti, LK, Mackensen, GB, Grocott, HP, Phillips-Bute, BG, and Mathew, JP. "The clinical significance of routine TEE in patients undergoing CABG with normal LV function." ANESTHESIOLOGY 93, no. 3A (September 2000): U149-U149. Link to Item
  - Ti, LK, Mackensen, GB, Grocott, HP, Phillips-Bute, BG, and Mathew, JP. "Apolipoprotein E4 increases atheroma burden in cardiac surgical patients." ANESTHESIOLOGY 93, no. 3A (September 2000): U153-U153. Link to Item
  - Grigore, AM, and Mathew, JP. "Con: Magnesium should not be administered to all coronary artery bypass graft surgery patients undergoing cardiopulmonary bypass." J Cardiothorac Vasc Anesth 14, no. 3 (June 2000): 344-346. Link to Item
  - Hilton, AK, Jaggers, J, and Mathew, J. "An unexpected flow abnormality." J Cardiothorac Vasc Anesth 14, no. 3 (June 2000): 347-349. Link to Item
  - East, CJ, Clements, F, Mathew, J, and Slaughter, TF. "Antiphospholipid syndrome and cardiac surgery: management of anticoagulation in two patients." Anesth Analg 90, no. 5 (May 2000): 1098-1101. Link to Item
  - Stanley, TO, Grocott, HP, Phillips-Bute, B, Laskowitz, D, Hilton, AK, Mathew, JP, Debruijn, N, and Newman, MF. "Aortic atheroma and the risk of stroke and encephalopathy after cardiac surgery." ANESTHESIA AND ANALGESIA 90, no. 4 (April 2000): SCA38-SCA38. Link to Item
  - Grigore, AM, and Mathew, JR. "Con magnesium should not be administered to all coronary artery bypass graft surgery patients undergoing cardiopulmonary bypass." Journal of Cardiothoracic and Vascular Anesthesia 14, no. 3 SUPPL. (January 1, 2000): 344-346. Full Text
  - Shanewise, JS, Cheung, AT, Aronson, S, Stewart, WJ, Weiss, RL, Mark, JB, Savage, RM, Sears-Rogan, P, Mathew, JP, Quiñones, MA, Cahalan, MK, and Savino, JS. "ASE/SCA guidelines for performing a comprehensive intraoperative multiplane transesophageal echocardiography examination: recommendations of the American Society of Echocardiography Council for Intraoperative Echocardiography and the Society of Cardiovascular Anesthesiologists Task Force for Certification in Perioperative Transesophageal Echocardiography." J Am Soc Echocardiogr 12, no. 10 (October 1999): 884-900. Link to Item
  - Shanewise, JS, Cheung, AT, Aronson, S, Stewart, WJ, Weiss, RL, Mark, JB, Savage, RM, Sears-Rogan, P, Mathew, JP, Quiñones, MA, Cahalan, MK, and Savino, JS. "ASE/SCA guidelines for performing a comprehensive intraoperative multiplane transesophageal echocardiography examination: recommendations of the American Society of Echocardiography Council for Intraoperative Echocardiography and the Society of Cardiovascular Anesthesiologists Task Force for Certification in Perioperative Transesophageal Echocardiography." Anesthesia and Analgesia 89, no. 4 (October 1999): 870-884. Full Text
  - East, CJ, Weatherwax, K, White, WD, Mathew, JP, and Reves, JG. "Bispectral (BIS) analysis during cardiopulmonary bypass (CPB): The impact of hypothermia on the hypnotic state." ANESTHESIOLOGY 91, no. 3A (September 1999): U288-U288. Link to Item
  - Harris, SN, Davis, E, Garwood, S, Fontes, ML, Mathew, JP, and Siravajian, M. "Gender differences in the incidence of aortic atheromatous disease detected by transesophageal echocardiography (TEE)." ANESTHESIA AND ANALGESIA 88, no. 4 (April 1999): U13-U13. Link to Item
  - Comunale, ME, Body, SC, Ley, C, Koch, C, Roach, G, Mathew, JP, Herskowitz, A, and Mangano, DT. "The concordance of intraoperative left ventricular wall-motion abnormalities and electrocardiographic S-T segment changes: association with outcome after coronary revascularization. Multicenter Study of Perioperative Ischemia (McSPI) Research Group." Anesthesiology 88, no. 4 (April 1998): 945-954. Link to Item
  - Fontes, ML, Mathew, J, Johnson, K, and Rafferty, T. "Bicuspid noncalcific aortic stenosis: diagnostic limitations of intraoperative transesophageal echocardiography." J Cardiothorac Vasc Anesth 12, no. 1 (February 1998): 58-60. Link to Item
  - Comunale, ME, Body, SC, Ley, C, Koch, C, Roach, G, Mathew, JP, Herskowitz, A, and Mangano, DT. "The concordance of intraoperative left ventricular wall-motion abnormalities and electrocardiographic S-T segment changes: Association with outcome after coronary revascularization." Anesthesiology 88, no. 4 (1998): 945-954. Full Text
  - Fontes, ML, Adams, J, Rosow, E, Mathew, J, and Degraff, AC. "Non-invasive cardiopulmonary function assessment system." Journal of Clinical Monitoring 13, no. 6 (December 1, 1997): 412-413.
  - Mathew, JP, Adam, J, Rosow, E, Fontes, ML, Davis, L, Barash, PG, and Gillam, MDL. "Cardiovascular pressure-dimension analysis system." Journal of Clinical Monitoring 13, no. 6 (December 1, 1997): 422-null.
  - Rinder, CS, Mathew, JP, Rinder, HM, Tracey, JB, Davis, E, and Smith, BR. "Lymphocyte and monocyte subset changes during cardiopulmonary bypass: effects of aging and gender." J Lab Clin Med 129, no. 6 (June 1997): 592-602. Link to Item
  - Jain, U, Body, SC, Bellows, W, Wolman, R, Mangano, CM, Mathew, J, Youngs, E, Wilson, R, Zhang, A, and Mangano, DT. "Multicenter study of target-controlled infusion of propofol-sufentanil or sufentanil-midazolam for coronary artery bypass graft surgery. Multicenter Study of Perioperative Ischemia (McSPI) Research Group." Anesthesiology 85, no. 3 (September 1996): 522-535. Link to Item
  - Mathew, JP, Parks, R, Savino, JS, Friedman, AS, Koch, C, Mangano, DT, and Browner, WS. "Atrial fibrillation following coronary artery bypass graft surgery: predictors, outcomes, and resource utilization. MultiCenter Study of Perioperative Ischemia Research Group." Jama 276, no. 4 (July 1996): 300-306. Full Text
  - Cheng, TO, Khan, SS, Mathew, JP, Parks, R, and Browner, WS. "Atrial fibrillation following coronary artery bypass graft surgery [1]." Journal of the American Medical Association 276, no. 21 (1996): 1719-1720.
  - Jain, U, Body, SC, Bellows, W, Wolman, R, Mangano, CM, Mathew, J, Youngs, E, Wilson, R, Zhang, A, and Mangano, DT. "Multicenter study of target-controlled infusion of propofol-sufentanil or sufentanil-midazolam for coronary artery bypass graft surgery." Anesthesiology 85, no. 3 (January 1, 1996): 522-535. Full Text
  - Mathew, JP, Parks, R, Savino, JS, Friedman, AS, Koch, C, Mangano, DT, and Browner, WS. "Atrial fibrillation following coronary artery bypass graft surgery: Predictors, outcomes, and resource utilization." Journal of the American Medical Association 276, no. 4 (1996): 300-306. Full Text
  - Mathew, JP, Rinder, CS, Tracey, JB, Auszura, LA, O'Connor, T, Davis, E, and Smith, BR. "Acadesine inhibits neutrophil CD11b up-regulation in vitro and during in vivo cardiopulmonary bypass." J Thorac Cardiovasc Surg 109, no. 3 (March 1995): 448-456. Full Text Link to Item
  - Mathew, J, Hines, JE, Toole, K, Johnson, SJ, James, OF, and Burt, AD. "Quantitative analysis of macrophages and perisinusoidal cells in primary biliary cirrhosis." Histopathology 25, no. 1 (July 1994): 65-70. Link to Item
  - Mathew, J, Hines, JE, James, OF, and Burt, AD. "Non-parenchymal cell responses in paracetamol (acetaminophen)-induced liver injury." J Hepatol 20, no. 4 (April 1994): 537-541. Link to Item
  - Leung, JM, Stanley, T, Mathew, J, Curling, P, Barash, P, Salmenpera, M, Reves, JG, Hollenberg, M, and Mangano, DT. "An initial multicenter, randomized controlled trial on the safety and efficacy of acadesine in patients undergoing coronary artery bypass graft surgery. SPI Research Group." Anesth Analg 78, no. 3 (March 1994): 420-434. Link to Item
  - Kleinman, B, Mathew, JP, and Fleisher, LA. "Electrocardiographic changes during cesarean section [8]." Anesthesiology 78, no. 5 (1993): 997-998.
  - Mathew, JP, Fleisher, LA, Rinehouse, JA, Sevarino, FB, Sinatra, RS, Nelson, AH, Prokop, EK, and Rosenbaum, SH. "ST segment depression during labor and delivery." Anesthesiology 77, no. 4 (October 1992): 635-641. Link to Item
  - Rinder, CS, Bonan, JL, Rinder, HM, Mathew, J, Hines, R, and Smith, BR. "Cardiopulmonary bypass induces leukocyte-platelet adhesion." Blood 79, no. 5 (March 1, 1992): 1201-1205. Link to Item
  - Hines, RL, Mathew, J, and McCloskey, G. "Hemodynamic monitoring: Past, present, and future." Seminars in Anesthesia 11, no. 2 (January 1, 1992): 138-149. (Review)
  - Rinder, CS, Mathew, JP, Rinder, HM, Bonan, J, Ault, KA, and Smith, BR. "Modulation of platelet surface adhesion receptors during cardiopulmonary bypass." Anesthesiology 75, no. 4 (October 1991): 563-570. Link to Item
  - Mathew, JP, Rosenbaum, SH, O'Connor, T, and Barash, PG. "Emergency tracheal intubation in the postanesthesia care unit: physician error or patient disease?." Anesth Analg 71, no. 6 (December 1990): 691-697. Link to Item
  - Ti, LK, Mathew, JP, Mackensen, GB, Grocott, HP, Saunders, AM, White, WD, Reves, JG, and Newman, MF. "Erratum: Effect of apolipoprotein E genotype on cerebral autoregulation during cardiopulmonary bypass (Store (July 2000) 32:7 (1514-1519))." Stroke 32, no. 11 (November 24, 2001): 2727-null.
- Book Sections
  - Friede, K, Mathew, JP, and Podgoreanu, MV. "Genomic basis of perioperative medicine." In Clinical Anesthesia: Seventh Edition. March 1, 2013.
- Other Articles
  - Hughes, GC, and Mathew, JP. "Invited Commentary." The Annals of thoracic surgery 101, no. 1 (January 2016): 152-153. Full Text
  - Castleberry, AW, Williams, JB, Daneshmand, MA, Honeycutt, E, Shaw, LK, Samad, Z, Lopes, RD, Alexander, JH, Mathew, JP, Velazquez, EJ, Milano, CA, and Smith, PK. "Response to letter regarding article, "surgical revascularization is associated with maximal survival in patients with ischemic mitral regurgitation: a 20-year experience"." Circulation 131, no. 11 (March 2015): e378-e379. (Letter) Full Text
  - Kertai, MD, Li, Y-W, Li, Y-J, Shah, SH, Kraus, WE, Fontes, ML, Stafford-Smith, M, Newman, MF, Podgoreanu, MV, Mathew, JP, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "G protein-coupled receptor kinase 5 gene polymorphisms are associated with postoperative atrial fibrillation after coronary artery bypass grafting in patients receiving β-blockers." Circulation. Cardiovascular Genetics 7, no. 5 (October 2014): 625-633. Full Text
  - McDonagh, DL, Mathew, JP, White, WD, Phillips-Bute, B, Laskowitz, DT, Podgoreanu, MV, Newman, MF, and Neurologic Outcome Research Group, . "Cognitive function after major noncardiac surgery, apolipoprotein E4 genotype, and biomarkers of brain injury." Anesthesiology 112, no. 4 (April 2010): 852-859. Full Text
  - Mackensen, GB, Ti, LK, Phillips-Bute, BG, Mathew, JP, Newman, MF, Grocott, HP, and Neurologic Outcome Research Group (NORG), . "Cerebral embolization during cardiac surgery: impact of aortic atheroma burden." Bja: British Journal of Anaesthesia 91, no. 5 (November 2003): 656-661. Full Text
  - Swaminathan, M, McCreath, BJ, Phillips-Bute, BG, Newman, MF, Mathew, JP, Smith, PK, Blumenthal, JA, Stafford-Smith, M, and Perioperative Outcomes Research Group, . "Serum creatinine patterns in coronary bypass surgery patients with and without postoperative cognitive dysfunction." Anesth Analg 95, no. 1 (July 2002): 1-8. Link to Item
  - Grigore, AM, Grocott, HP, Mathew, JP, Phillips-Bute, B, Stanley, TO, Butler, A, Landolfo, KP, Reves, JG, Blumenthal, JA, Newman, MF, and Neurologic Outcome Research Group of the Duke Heart Center, . "The rewarming rate and increased peak temperature alter neurocognitive outcome after cardiac surgery." Anesthesia and Analgesia 94, no. 1 (January 2002): 4-10. Full Text
- Conference Papers
  - Karhausen, JA, Qi, W, Smeltz, AM, Li, Y-J, Shah, SH, Kraus, WE, Mathew, JP, Podgoreanu, MV, Kertai, MD, and Duke Perioperative Genetics Safety Outcomes (PEGASUS) Investigative Team, . "Genome-Wide Association Study Links Receptor Tyrosine Kinase Inhibitor Sprouty 2 to Thrombocytopenia after Coronary Artery Bypass Surgery." September 2018. Full Text
  - Waldron, NH, Cooter, M, Haney, JC, Schroder, JN, Milano, CA, Piccini, JP, and Mathew, JP. "Temporary Neurotoxin Treatment to Prevent Postoperative Atrial Fibrillation." December 12, 2017. Link to Item
  - Piccini, JP, Browndyke, J, Cooter, M, Bisanar, T, Flynn, A, Fudim, M, Waldron, NH, Newman, MF, Daubert, JP, and Mathew, JP. "Neurocognitive Function in Atrial Fibrillation: Catheter Ablation versus Medical Management." Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium. Anaheim, CA. November 11, 2017 - November 15, 2017.: LIPPINCOTT WILLIAMS & WILKINS, November 14, 2017. Link to Item
  - Sigurdsson, MI, Waldron, NH, Manning, MW, Quinones, QJ, Mathew, JP, and Podgoreanu, MV. "Genomic Classification of Permanent versus New-onset Postoperative Atrial Fibrillation Using Atrial Myocardial Gene Expression Profiling." Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium. Anaheim, CA. November 11, 2017 - November 15, 2017.: LIPPINCOTT WILLIAMS & WILKINS, November 14, 2017. Link to Item
  - Grant, SA, Van de Ven, TJ, Grichnik, K, Scouras, M, Gadsden, J, Martin, G, and Mathew, JP. "A Dose Finding Study of the Ideal Analgesic Dose of Intravenous Dexamethasone for Total Knee Arthroplasty." Annual Meeting and International Science Symposium of the International-Anesthesia-Research-Society. Washington, DC. May 6, 2017 - May 9, 2017.: LIPPINCOTT WILLIAMS & WILKINS, May 1, 2017. Link to Item
  - Cheruku, S, Kertai, MD, Qi, W, Li, Y-J, Hughes, GC, Mathew, JP, and Karhausen, J. "Mast Cell Activation During Aortic Repair Requiring Circulatory Arrest is Associated With Hemodynamic Instability and Indications of End-Organ Injury." November 10, 2015. Link to Item
  - Povsic, TJ, Swaminathan, M, Kelly, F, Zavodni, KL, Adams, SD, Milano, CA, Newman, MF, Mathew, JP, Goldschmidt-Clermont, PJ, and Peterson, ED. "Bone marrow progenitor cell stores impact circulating EPC levels and are depleted in elderly subjects." 57th Annual Scientific Session of the American-College-of-Cardiology. Chicago, IL. March 29, 2008 - April 1, 2008.: ELSEVIER SCIENCE INC, March 11, 2008. Link to Item
  - Podgoreanu, MV, White, WD, Mathew, JP, Stafford-Smith, M, Welsby, IJ, Newman, MF, and Schwinn, DA. "Inflammatory gene polymorphisms and risk of postoperative myocardial infarction following cardiac surgery." October 25, 2005. Link to Item
  - Podgoreanu, MV, White, WD, Mathew, JP, Stafford-Smith, M, Welsby, IJ, Newman, MF, and Schwinn, DA. "Inflammatory gene polymorphisms and risk of postoperative myocardial infarction following cardiac surgery." October 25, 2005. Link to Item
  - Brzezinski, M, Michelotti, GA, Sharpe-Kass, M, Mathew, JP, and Schwinn, DA. "Differential protein expression in patients with atrial fibrillation." March 23, 2004. Link to Item
  - Mathew, JP, Fontes, MA, Tudor, LC, Duke, P, Hsu, PH, and Mangano, DT. "Natural history of atrial fibrillation after coronary artery bypass grafting." October 28, 2003. Link to Item
  - Mathew, JP, Fontes, MA, Tudor, LC, Ramsay, J, Hsu, PH, and Mangano, DT. "A Multicenter risk index for atrial fibrillation after coronary artery bypass graft surgery." October 28, 2003. Link to Item
  - Podgoreanu, MV, Booth, JV, White, WD, Phillips-Bute, B, Michelotti, GA, Mathew, JP, Newman, MF, and Schwinn, DA. "Beta adrenergic receptor polymorphisms and risk of adverse events following cardiac surgery." October 28, 2003. Link to Item
  - Booth, JV, Phillips-Bute, B, McCants, CC, Smith, PK, Mathew, JP, and Newman, MF. "Low serum magnesium levels predict decreased event-free survival at 6 months and 1 year following coronary artery bypass graft surgery." October 23, 2001. Link to Item

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