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Matthew James Hilton
Professor in Orthopaedic Surgery
Orthopaedic Surgery
matthew.hilton@duke.edu
450 Research Drive, LSRC B321C, DUMC 91009, Durham, NC 27710
91009, Durham, NC 27710
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AT A GLANCE
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Credentials
Education
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Academic Experience
Current Appointments & Affiliations
Previous Appointments & Affiliations
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Expertise
Keywords
Global Scholarship
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Research
Selected Grants
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Publications
Selected Publications
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Artistic Works / Events
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Teaching
Recent Courses
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Advising & Mentoring
Available to Mentor
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Recognition
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Professional Activities
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Selected Grants
Fibro/Adipogenic Progenitor Metabolic Reprogramming for Age-Related Muscle Fibrosis
Research
Advisor ·
Awarded by National Institutes of Health ·
2024 - 2029
Boston Children's/UCLA/Duke Next Generation Regeneration for Osteoarthritis (BUD NextGenRegen for OA)
Research
Investigator ·
Awarded by Advanced Research Projects Agency for Health ·
2024 - 2029
Role of GDF15 in genotoxic stress induced regulation of skeletal muscle fibro-adipogenic progenitor activity, fibrosis, growth, and regeneration.
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2024 - 2029
Engineering a Human Skeletal Muscle Tissue Model of LGMD2B
Research
Collaborator ·
Awarded by National Institutes of Health ·
2023 - 2028
Targeting the HIF-2 Signaling Pathway as a Radioprotective Strategy for Bone
Research
Co Investigator ·
Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases ·
2022 - 2027
More
Fibro/Adipogenic Progenitor Metabolic Reprogramming for Age-Related Muscle Fibrosis
Research
Advisor ·
Awarded by National Institutes of Health ·
2024 - 2029
Boston Children's/UCLA/Duke Next Generation Regeneration for Osteoarthritis (BUD NextGenRegen for OA)
Research
Investigator ·
Awarded by Advanced Research Projects Agency for Health ·
2024 - 2029
Role of GDF15 in genotoxic stress induced regulation of skeletal muscle fibro-adipogenic progenitor activity, fibrosis, growth, and regeneration.
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2024 - 2029
Engineering a Human Skeletal Muscle Tissue Model of LGMD2B
Research
Collaborator ·
Awarded by National Institutes of Health ·
2023 - 2028
Targeting the HIF-2 Signaling Pathway as a Radioprotective Strategy for Bone
Research
Co Investigator ·
Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases ·
2022 - 2027
Training Program in Developmental and Stem Cell Biology
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
2001 - 2027
Resorbable, Phsophorylated Poly(ester urea) Surgical Adhesive to Enhance Fracture Healing
Research
Advisor ·
Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases ·
2021 - 2026
Cell and Molecular Biology Training Program
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
2021 - 2026
Genetic and Therapeutic Approaches to Alleviate the Pathology of Massive Rotator Cuff Tears
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2024 - 2026
The role of fibro-adipogenic progenitors in the rotator cuff tear pathology
Fellowship
Principal Investigator ·
Awarded by National Institutes of Health ·
2024 - 2026
Next-gen stealth polymer for biofilm-resistant orthopedic implant coatings
Research
Co Investigator ·
Awarded by American Foundation for Surgery of the Hand ·
2023 - 2025
Genetic and Genomics Training Grant
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
2020 - 2025
CaMKK2 Signaling in Osteoarthritis
Research
Principal Investigator ·
Awarded by Indiana University ·
2020 - 2025
Duke CTSA (TL1) Year 5
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
2018 - 2024
Notch Signaling in Endochondral Bone Development
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2018 - 2023
Notch Signaling in non-myogenic mesenchymal cells regulates muscle development
Fellowship
Principal Investigator ·
Awarded by National Institutes of Health ·
2020 - 2023
Notch Signaling in Joint Cartilage Maintenance and Arthritis
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2012 - 2022
Zeiss Lightsheet Upgrade to Expand Imaging Capabilities
Equipment
Minor User ·
Awarded by National Institutes of Health ·
2021 - 2022
The role of proline metabolism during osteoblast differentiation and bone formation
Research
Principal Investigator ·
Awarded by University of Texas Southwestern Medical Center ·
2021 - 2021
Role of Glutamine Metabolism during Osteoblast Differentiation and Bone Formation
Research
Principal Investigator ·
Awarded by University of Texas Southwestern Medical Center ·
2021 - 2021
Genetics Training Grant
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
1979 - 2020
Organization and Function of Cellular Structure
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
1975 - 2020
Investigation of the roles for CaVa1.2 in non-excitable tissue during development
Research
Principal Investigator ·
Awarded by Weill Medical College of Cornell University ·
2016 - 2017
Study of Osteoblast Regulation in TNF-Mediated Bone Loss
Research
Principal Investigator ·
Awarded by University of Rochester ·
2014 - 2016
Notch Signaling in Cartilage Development
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2010 - 2015
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