Matthew Sinclair

Journal Article Adv Kidney Dis Health · January 2024 Individuals living with CKD are disproportionately burdened by a multitude of adverse clinical and person-centered outcomes. When patients transition from advanced kidney disease to kidney failure, the psychosocial effects as well as social determinants of ... Full text Link to item Cite

The diabetes cardiovascular outcomes trials and racial and ethnic minority enrollment: impact, barriers, and potential solutions.

Journal Article Front Public Health · 2024 Type 2 diabetes (T2D) affects millions of individuals worldwide and is a well-documented risk factor for cardiovascular (CV) disease and chronic kidney disease, both of which are leading causes of mortality. Racial and ethnic minority groups in the US, inc ... Full text Link to item Cite

Response to COVID-19: The Outpatient Dialysis Setting.

Journal Article Clin J Am Soc Nephrol · July 1, 2023 Full text Link to item Cite

Association of Follow-up Blood Cultures With Mortality in Patients With Gram-Negative Bloodstream Infections: A Systematic Review and Meta-analysis.

Journal Article JAMA Netw Open · September 1, 2022 IMPORTANCE: Obtaining follow-up blood cultures (FUBCs) in patients with Staphylococcus aureus bloodstream infection (BSI) is standard practice, although its utility in patients with gram-negative bacterial BSI (GN-BSI) is unclear. OBJECTIVE: To examine whe ... Full text Link to item Cite

Staphylococcus aureus Bacteremia Among Patients Receiving Maintenance Hemodialysis: Trends in Clinical Characteristics and Outcomes.

Journal Article Am J Kidney Dis · March 2022 RATIONALE & OBJECTIVE: Staphylococcus aureus (Saureus) bacteremia (SAB) is associated with morbidity and mortality in patients receiving maintenance hemodialysis (HD). We evaluated changes in clinical and bacterial characteristics, and their associations w ... Full text Open Access Link to item Cite

Bacterial genotype and clinical outcomes in solid organ transplant recipients with Staphylococcus aureus bacteremia.

Journal Article Transpl Infect Dis · December 2021 INTRODUCTION: Outcomes from Staphylococcus aureus bacteremia (SAB) in solid organ transplant (SOT) recipients are poorly understood. METHODS: This is a prospective cohort study comparing the bacterial genotype and clinical outcomes of SAB among SOT and non ... Full text Link to item Cite

Infective endocarditis and solid organ transplantation: Only worse outcomes during initial transplantation hospitalization.

Journal Article Am Heart J · October 2021 BACKGROUND: The epidemiology, and outcome of infective endocarditis (IE) among solid organ transplant (SOT) recipients is unknown. METHODS: We used data from the 2013-2018 Nationwide Readmissions Database (NRD). IE- and SOT-associated hospitalizations were ... Full text Open Access Link to item Cite

Bacteremia in solid organ transplant recipients as compared to immunocompetent patients: Acute phase cytokines and outcomes in a prospective, matched cohort study.

Journal Article Am J Transplant · June 2021 We undertook a prospective, matched cohort study of patients with Staphylococcus aureus bacteremia (SAB) and gram-negative bacteremia (GNB) to compare the characteristics, outcomes, and chemokine and cytokine response in transplant recipients to immunocomp ... Full text Open Access Link to item Cite

Renin-angiotensin system blockade in the COVID-19 pandemic.

Journal Article Clin Kidney J · March 2021 In the early months of the coronavirus disease 2019 (COVID-19) pandemic, a hypothesis emerged suggesting that pharmacologic inhibitors of the renin-angiotensin system (RAS) may increase COVID-19 severity. This hypothesis was based on the role of angiotensi ... Full text Link to item Cite

Regional and Racial Disparities in HIV-Related Kidney Disease.

Journal Article Contrib Nephrol · 2021 Clinical Background and Epidemiology: Worldwide, an estimated 38 million people are living with HIV infection. The classic kidney disease of HIV infection, commonly known as HIV-associated nephropathy, is a collapsing form of focal segmental glomeruloscler ... Full text Link to item Cite

Prescribing rates and characteristics of recipients of tenofovir-containing regimens before and after market entry of tenofovir alafenamide.

Journal Article J Manag Care Spec Pharm · December 2020 BACKGROUND: Tenofovir alafenamide (TAF) is a new formulation of tenofovir disoproxil fumarate (TDF) that was approved in 2015. While clinical trial evidence suggests that TAF has more favorable outcomes related to kidney injury and loss of bone mineral den ... Full text Link to item Cite

An international cohort study of autosomal dominant tubulointerstitial kidney disease due to REN mutations identifies distinct clinical subtypes.

Journal Article Kidney Int · December 2020 There have been few clinical or scientific reports of autosomal dominant tubulointerstitial kidney disease due to REN mutations (ADTKD-REN), limiting characterization. To further study this, we formed an international cohort characterizing 111 individuals ... Full text Link to item Cite

A Novel Curriculum to Prepare Internal Medicine Residents for Fellowship Interviews.

Journal Article J Med Educ Curric Dev · 2019 BACKGROUND: Applications to the Fellowship Match through the National Resident Matching Program (NRMP) Specialties Matching Service (SMS) are at an all-time high. Data regarding the preparedness of medical residents who go through the interview process is ... Full text Link to item Cite