Scholars@Duke
Brooks W. McCuen II

Brooks W. McCuen II

Robert Machemer Distinguished Professor Emeritus of Ophthalmology
Ophthalmology, Vitreoretinal Diseases & Surgery
mccue001@mc.duke.edu
Box 3802 Med Ctr, Durham, NC 27710
2351 Erwin Road, Durham, NC 27710

Selected Publications

Comparison of Visual Outcomes in Coats' Disease: A 20-Year Experience.

Journal Article Ophthalmology · September 2017 PURPOSE: To report differences in visual acuities among patients with Coats' disease who sought treatment at a tertiary care university-based practice. DESIGN: Single-center retrospective cohort study. PARTICIPANTS: Patients with Coats' disease diagnosed c ... Full text Link to item Cite

Dislocation of the donor graft to the posterior segment in descemet stripping automated endothelial keratoplasty.

Journal Article Am J Ophthalmol · April 2012 PURPOSE: To report a series of dislocations of the donor graft into the posterior segment associated with Descemet stripping endothelial keratoplasty (DSAEK) and to identify possible risk factors for dislocation and clinical outcomes. DESIGN: Retrospective ... Full text Link to item Cite

Vitrectomy without laser treatment or gas tamponade for macular detachment associated with an optic disc pit.

Journal Article Ophthalmology · April 2012 PURPOSE: To evaluate the clinical outcomes after vitrectomy, without gas tamponade or laser photocoagulation to the margin of the optic nerve, for the treatment of macular detachment associated with optic disc pits and to characterize retinal manifestation ... Full text Link to item Cite

Unanticipated vision loss after pars plana vitrectomy.

Journal Article Surv Ophthalmol · 2012 Although advances in vitreoretinal surgical techniques and technology have helped to minimize the risks associated with surgical manipulation of the retina, retinal pigment epithelium, and optic nerve, unanticipated or unexplained visual loss still occurs. ... Full text Link to item Cite

Intravitreal triamcinolone acetonide in the treatment of macular retinal detachment associated with morning glory anomaly.

Journal Article Retin Cases Brief Rep · 2009 PURPOSE: To report the successful treatment of a case of recurrent macular retinal detachment associated with morning glory anomaly using intravitreal triamcinolone acetonide. METHODS: A 53-year-old man with a history of bilateral morning glory anomaly and ... Full text Link to item Cite

Relationship between optical coherence tomography-measured central retinal thickness and visual acuity in diabetic macular edema.

Conference Ophthalmology · March 2007 OBJECTIVE: To compare optical coherence tomography (OCT)-measured retinal thickness and visual acuity in eyes with diabetic macular edema (DME) both before and after macular laser photocoagulation. DESIGN: Cross-sectional and longitudinal study. PARTICIPAN ... Full text Link to item Cite

Natural history of foveolar lucencies observed by optical coherence tomography after macular hole surgery.

Journal Article Retina · January 2007 PURPOSE: To describe the incidence, course, and anatomic and functional outcomes of foveolar lucencies observed by optical coherence tomography after macular hole surgery. METHODS: Retrospective chart review of all idiopathic macular hole surgeries perform ... Full text Link to item Cite

A prospective, open-label, dose-escalating study of low molecular weight heparin during repeat vitrectomy for PVR and severe diabetic retinopathy.

Journal Article Graefes Arch Clin Exp Ophthalmol · July 2005 BACKGROUND: To determine the maximum tolerated dose (MTD) of enoxaparin, a low molecular weight heparin (LMWH) was used during repeat vitrectomy for rhegmatogenous retinal detachment with proliferative vitreoretinopathy (PVR) and severe diabetic retinopath ... Full text Link to item Cite

Relaxing retinotomy in proliferative vitreoretinopathy surgery: Long term results

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · January 1, 2005 Link to item Cite

Radial optic neurotomy in the porcine eye without retinal vein occlusion.

Journal Article Arch Ophthalmol · August 2004 OBJECTIVE: To demonstrate the histopathologic changes in the porcine eye without retinal vein occlusion after radial optic neurotomy (RON). METHODS: A RON was performed in 14 normal eyes of 12 Yorkshire Cross pigs. One radial stab incision at the edge of t ... Full text Link to item Cite

Effects of indocyanine green on the retina and retinal pigment epithelium in a porcine model of retinal hole.

Journal Article Retina · April 2004 PURPOSE: This study was designed to emulate human macular hole surgery and to test the effects of indocyanine green (ICG) on the retina and retinal pigment epithelium (RPE). METHODS: Yorkshire Cross pigs (n = 23) underwent vitrectomy, separation of the pos ... Full text Link to item Cite

Foveal detachments and cysts observed by optical coherence tomography after macular hole surgery

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2004 Link to item Cite

Silicone oil versus gas tamponade: author reply

Journal Article Ophthalmology · April 2004 Full text Cite

Comparison of silicone oil versus gas tamponade in the treatment of idiopathic full-thickness macular hole.

Journal Article Ophthalmology · June 2003 PURPOSE: To compare anatomic and functional outcomes of macular hole surgery with either silicone oil or C(3)F(8) gas tamponade. DESIGN: Retrospective comparative interventional study. PARTICIPANTS: Fifty-four eyes of 51 patients underwent pars plana vitre ... Full text Link to item Cite

Traumatic macular holes: A comparison of surgical repair to natural history

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · May 1, 2003 Link to item Cite

Lensectomy and vitrectomy decrease the rate of photoreceptor loss in rhodopsin P347L transgenic pigs.

Journal Article Graefes Arch Clin Exp Ophthalmol · April 2003 BACKGROUND: Photoreceptor degeneration in retinitis pigmentosa (RP) runs an inevitable, gradually progressive course. A wide variety of growth factors of different origins have been shown to slow the rate of degeneration in some rodent models of RP. Recent ... Full text Link to item Cite

A matched study of primary scleral buckle placement during repair of posterior segment open globe injuries.

Journal Article Br J Ophthalmol · January 2003 AIMS: To compare the visual and anatomical outcomes of patients who underwent primary scleral buckle (SB) placement during posterior segment open globe repair with matched control patients who did not undergo primary SB placement. METHODS: Patients who und ... Full text Link to item Cite

RGD peptide-assisted vitrectomy to facilitate induction of a posterior vitreous detachment: a new principle in pharmacological vitreolysis.

Journal Article Curr Eye Res · December 2002 PURPOSE: To evaluate a new concept in pharmacological vitreolysis by studying the efficacy of intravitreal RGD peptide-assisted vitrectomy in facilitating the separation of the posterior cortical vitreous from the retinal surface in an animal model. METHOD ... Full text Link to item Cite

Pars plana vitrectomy, subretinal injection of tissue plasminogen activator, and fluid-gas exchange for displacement of thick submacular hemorrhage in age-related macular degeneration.

Journal Article Am J Ophthalmol · February 2001 PURPOSE: To evaluate a new procedure for displacement of large, thick submacular hemorrhage in patients with age-related macular degeneration. METHODS: Retrospective review of 11 eyes of 11 patients with age-related macular degeneration and thick submacula ... Full text Link to item Cite

Dispase facilitates posterior vitreous detachment during vitrectomy in young pigs.

Journal Article Retina · 2001 PURPOSE: To evaluate the role of intravitreal dispase in conjunction with pars plana vitrectomy to facilitate the creation of a posterior vitreous detachment (PVD) in young pig eyes. METHODS: Twenty-four eyes of 24 animals were randomized to receive an int ... Full text Link to item Cite

Primary scleral buckling in open-globe injury involving the posterior segment.

Journal Article Ophthalmology · October 2000 PURPOSE: To determine whether scleral buckle placement at the time of primary repair of open-globe injury of the posterior segment is beneficial. DESIGN: Retrospective, comparative, nonrandomized interventional study. PARTICIPANTS: One hundred twenty-five ... Full text Link to item Cite

Dispase-assisted vitrectomy facilitates posterior vitreous detachment in young porcines

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · March 15, 2000 Link to item Cite

Synaptic plasticity in mammalian retinas induced by rod-specific mutations

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · March 15, 2000 Link to item Cite

Clear lens extraction decreases the rate of photoreceptor loss in rhodopsin P347L transgenic pigs

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · March 15, 2000 Link to item Cite

Features of macular hole closure in the early postoperative period using optical coherence tomography.

Journal Article Retina · 2000 PURPOSE: Studying the retina in the early postoperative period after macular hole surgery is difficult because of the limitation of imaging of the fundus through a gas tamponade. Silicone oil was shown recently to be an effective alternative to gas for mac ... Link to item Cite

Electron immunocytochemical analysis of posterior hyaloid associated with diabetic macular edema.

Journal Article Retina · 2000 BACKGROUND: Tangential traction in the macula from a thickened posterior hyaloid of the vitreous has been implicated as a cause of diffuse diabetic macular edema. Vitrectomy with peeling of the posterior hyaloid has been shown to reduce retinovascular leak ... Full text Link to item Cite

Diagnosis of vitreoretinal adhesions in macular disease with optical coherence tomography.

Journal Article Retina · 2000 PURPOSE: To compare the relative incidence of vitreoretinal adhesions associated with partial vitreous separation within the macula diagnosed with optical coherence tomography (OCT) with that of those diagnosed with biomicroscopy. METHODS: The authors obta ... Link to item Cite

Silicone oil tamponade to seal macular holes without position restrictions.

Journal Article Ophthalmology · November 1998 OBJECTIVE: The authors performed a study to determine the effectiveness and safety of silicone oil as a substitute for gas to fill the vitreous cavity to treat macular holes. DESIGN: Multicenter, nonrandomized, interventional trial. PARTICIPANTS: Thirty-se ... Full text Link to item Cite

Peripheral retinal cryotherapy for postvitrectomy diabetic vitreous hemorrhage in phakic eyes.

Journal Article Am J Ophthalmol · July 1998 PURPOSE: To review the anatomic and visual outcomes of a consecutive series of phakic patients with postoperative diabetic vitreous hemorrhage (PDVH) who underwent revision vitrectomy with peripheral retinal cryotherapy. METHODS: We performed a retrospecti ... Full text Link to item Cite

Panretinal laser photocoagulation failed to retard degeneration in rhodopsin P347L transgentc pigs

Journal Article Investigative Ophthalmology and Visual Science · December 1, 1997 Purpose Various tines of evidence suggest that injury to the eye, or to the retina, may retard retina! degeneration in animal models, probably by causing retinal cells to release factors that may promote cell survival. In the RCS rat, preservation of retin ... Cite

Panretinal laser photocoagulation failed to retard degeneration in rhodopsin P347L transgenic pigs

Journal Article INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · March 15, 1997 Link to item Cite

Vitrectomy with silicone oil or long-acting gas in eyes with severe proliferative vitreoretinopathy: results of additional and long-term follow-up. Silicone Study report 11.

Journal Article Arch Ophthalmol · March 1997 BACKGROUND: The Silicone Study evaluated the outcomes of vitreoretinal surgery for retinal detachment with proliferative vitreoretinopathy (PVR). OBJECTIVE: To evaluate short-term (up to 36 months) outcomes in eyes randomized to silicone oil or perfluoropr ... Full text Link to item Cite

Surgical removal of subfoveal neovascularization in idiopathic juxtafoveolar retinal telangiectasis.

Journal Article Retina · 1997 PURPOSE: To investigate the efficacy of the surgical removal of subfoveal choroidal neovascularization in patients with type 2A idiopathic juxtafoveolar retinal telangiectasis. METHODS: Two patients with bilateral acquired idiopathic juxtafoveolar retinal ... Full text Link to item Cite

Subretinal hemorrhages in proliferative diabetic retinopathy.

Journal Article Retina · 1997 PURPOSE: To describe the clinical features of patients with advanced proliferative diabetic retinopathy who underwent vitrectomy and were found to have subretinal hemorrhages. METHODS: The authors conducted a retrospective study of 49 patients with complic ... Full text Link to item Cite

Visual field loss after macular hole surgery.

Journal Article Ophthalmology · July 1996 BACKGROUND: Vitrectomy has been successfully used for treating idiopathic macular holes. Although macular hole surgery has been successful and is generally regarded as a safe procedure, various complications have been reported. The authors report eight pat ... Full text Link to item Cite

Tissue plasminogen activator for preserving inferior peripheral iridectomy patency in eyes with silicone oil.

Journal Article Ophthalmology · February 1996 PURPOSE: An inferior peripheral iridectomy (IPI) was used to prevent forward migration of silicone oil in vitrectomized eyes; however, in approximately one third of eyes, the IPI closed spontaneously. Occlusion of the IPI by fibrin is believed to be an ear ... Full text Link to item Cite

Condensation on IOLs during fluid-air exchange - Reply

Journal Article OPHTHALMOLOGY · February 1, 1996 Link to item Cite

Treatment of migraine headache after ocular surgery with intravenous metoclopramide hydrochloride.

Journal Article Am J Ophthalmol · January 1996 PURPOSE: To alert ophthalmologists that prolonged or severe postoperative periocular pain and nausea may be caused by migraine. METHODS: We examined two patients who had a history of migraine and had severe episodes of prolonged periocular pain and nausea ... Full text Link to item Cite

POSTERIOR SURFACE CONDENSATION ON SILICONE IOLS - REPLY

Journal Article OPHTHALMOLOGY · October 1, 1995 Link to item Cite

Clinicopathologic correlation of surgically removed macular hole opercula.

Journal Article Am J Ophthalmol · August 1995 PURPOSE: To determine the ultrastructural characteristic of the operculum associated with macular holes. METHODS: We developed instrumentation and a technique to capture the operculum observed with macular holes. Two opercula were studied by transmission e ... Full text Link to item Cite

Visual acuity as a prognostic indicator in stage I macular holes. The Vitrectomy for Prevention of Macular Hole Study Group.

Journal Article Am J Ophthalmol · July 1995 PURPOSE/METHODS: To evaluate the role of initial visual acuity as a factor for progressive loss of vision or progression to a full-thickness macular hole in eyes with stage I macular holes (tractional foveal detachment without dehiscence). The study popula ... Full text Link to item Cite

Condensation on the posterior surface of silicone intraocular lenses during fluid-air exchange.

Journal Article Ophthalmology · May 1995 PURPOSE: Posterior chamber foldable silicone intraocular lenses (IOLs) are becoming increasingly prevalent in patients undergoing a pars plana vitrectomy with fluid-air exchange. The authors report an important limitation of foldable silicone IOLs during f ... Full text Link to item Cite

Authors' reply

Journal Article Ophthalmology · January 1, 1995 Full text Cite

Inferior peripheral iridectomy in patients receiving silicone oil. Rates of postoperative closure and effect on oil position.

Journal Article Retina · 1995 BACKGROUND: Silicone oil tamponade is used in treating retinal detachments, but silicone-associated complications remain frequent. Keratopathy and acute pupillary block glaucoma are related to migration of silicone oil into the anterior chamber. Since 1985 ... Link to item Cite

Primary intraocular lens implantation in the setting of penetrating ocular trauma.

Journal Article Ophthalmology · January 1995 PURPOSE: To evaluate the clinical outcome of patients who underwent lensectomy and intraocular lens (IOL) implantation at the time of primary repair of a penetrating ocular injury. METHODS: A review of 14 patients who sustained cataracts and lens rupture i ... Full text Link to item Cite

Removal of optic disc stalks during diabetic vitrectomy.

Journal Article Retina · 1995 BACKGROUND: The morphologic features and clinical consequences of removing residual optic disc stalks during vitrectomy for complications of diabetic retinopathy have not been described. METHODS: Twenty-four residual optic disc stalks that were surgically ... Full text Link to item Cite

The efficacy of silicone oil for complicated retinal detachments in the pediatric population.

Journal Article Arch Ophthalmol · June 1994 OBJECTIVE: To evaluate the efficacy of silicone oil as an intraocular tamponade for complicated retinal detachments in the pediatric population. DESIGN: Case series. SETTING: Referral practice at a major university hospital eye center. PATIENTS: Consecutiv ... Full text Link to item Cite

The effects of silicone oil removal. Silicone Study Report 6.

Journal Article Arch Ophthalmol · June 1994 OBJECTIVE: To evaluate the advisability of removing silicone oil from eyes after surgery for severe (with a classification of at least C-3) proliferative vitreoretinopathy. DESIGN: Subgroup analysis of the Silicone Study, a randomized, multicentered, surgi ... Full text Link to item Cite

Vitrectomy for prevention of macular holes. Results of a randomized multicenter clinical trial. Vitrectomy for Prevention of Macular Hole Study Group.

Conference Ophthalmology · June 1994 PURPOSE: The purpose of this study is to assess the benefit of vitreous surgery in preventing full-thickness macular holes in patients with impending (stage 1) macular holes. METHODS: A prospective randomized multicenter clinical trial was conducted on pat ... Full text Link to item Cite

DIABETIC-RETINOPATHY SCREENING BY PRIMARY-CARE PHYSICIANS

Journal Article INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · March 15, 1994 Link to item Cite

Treatment and pathogenesis of traumatic chorioretinal rupture (sclopetaria).

Journal Article Am J Ophthalmol · February 15, 1994 Eight eyes (seven patients) with traumatic chorioretinal rupture (sclopetaria) from severe ocular trauma were examined. All seven patients were referred with diagnoses of retinal detachment, giant retinal tear, or ruptured globe. Instead, all eyes had larg ... Full text Link to item Cite

Silicone Oil vs Perfluoropropane Gas as a Postoperative Retinal Tamponade-Reply

Journal Article Archives of Ophthalmology · January 1, 1994 Full text Cite

THE EFFICACY OF SILICONE OIL FOR COMPLICATED RETINAL DETACHMENTS IN THE PEDIATRIC POPULATION

Journal Article INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · March 15, 1993 Link to item Cite

Vitrectomy with silicone oil or perfluoropropane gas in eyes with severe proliferative vitreoretinopathy. Silicone Study Report 3.

Journal Article Retina · 1993 Between 1985 and 1990, 340 eyes with rhegmatogenous retinal detachment (RRD) and severe (stage C3 or worse) proliferative vitreoretinopathy (PVR) were treated with vitrectomy and randomly selected to receive perfluoropropane gas or silicone oil; 183 eyes h ... Full text Link to item Cite

Efficacy of fluid-air exchange for postvitrectomy diabetic vitreous hemorrhage.

Journal Article Am J Ophthalmol · October 15, 1992 We reviewed the records of 33 fluid-air exchanges to assess the efficacy of fluid-air exchange in the management of recurrent vitreous cavity hemorrhage after vitrectomy for proliferative diabetic retinopathy. Fluid-air exchange alone was successful in cle ... Full text Link to item Cite

Measurement of preretinal oxygen tension in the vitrectomized human eye using fluorine-19 magnetic resonance spectroscopy.

Journal Article Arch Ophthalmol · August 1992 We obtained oxygen measurements from a human eye that contained small preretinal droplets of perfluorotributylamine (FTBA) by using fluorine-19 magnetic resonance spectroscopy. These droplets were the remainder of a larger volume of FTBA that was used as a ... Full text Link to item Cite

Vitrectomy with silicone oil or sulfur hexafluoride gas in eyes with severe proliferative vitreoretinopathy: results of a randomized clinical trial. Silicone Study Report 1.

Journal Article Arch Ophthalmol · June 1992 Between September 1985 and September 1987, 101 eyes with rhegmatogenous retinal detachment and severe (with a classification of at least C-3) proliferative vitreoretinopathy but without prior vitrectomy were treated with vitrectomy and randomized to either ... Full text Link to item Cite

Vitrectomy with silicone oil or perfluoropropane gas in eyes with severe proliferative vitreoretinopathy: results of a randomized clinical trial. Silicone Study Report 2.

Journal Article Arch Ophthalmol · June 1992 Between September 1987 and October 1990, 265 eyes with rhegmatogenous retinal detachment and severe (with a classification of at least C-3) proliferative vitreoretinopathy were treated with vitrectomy and randomized to treatment with perfluoropropane gas o ... Full text Link to item Cite

Retinal oxygenation and laser treatment in patients with diabetic retinopathy.

Journal Article Am J Ophthalmol · January 15, 1992 The oxygen tension in the preretinal vitreous cavity was measured in human patients undergoing vitreous operations for proliferative diabetic retinopathy. The oxygen tension was significantly higher (P = .004) over areas of retina that had been treated wit ... Full text Link to item Cite

Results of penetrating keratoplasty associated with silicone oil retinal tamponade.

Journal Article Ophthalmology · August 1991 A review of 14 patients who underwent corneal transplantation after intravitreal silicone oil tamponade included an average follow-up of 28 months. Mean graft survival was 25 months (range, 2 to 61 months). Frequency of graft failure was 43% (6 of 14) with ... Full text Link to item Cite

Methods, statistical features, and baseline results of a standardized, multicentered ophthalmologic surgical trial: the Silicone Study.

Journal Article Control Clin Trials · June 1991 This article describes the trial design and baseline results for the Silicone Study, a multicenter, randomized surgical trial designed to compare the effectiveness of silicone fluid versus long-acting gas in the treatment of proliferative vitreoretinopathy ... Full text Link to item Cite

The management of retinal detachments associated with choroidal colobomas by vitreous surgery.

Journal Article Am J Ophthalmol · March 15, 1991 We used vitreous surgery to treat seven patients (eight eyes) with complicated retinal detachments associated with choroidal colobomas. All eyes had large choroidal colobomas and no evidence of peripheral retinal breaks. Small, atrophic breaks were detecte ... Full text Link to item Cite

The use of silicone oil in uveitis and hypotony.

Journal Article Retina · 1991 Profound hypotony associated with loss of vision complicating bilateral chronic uveitis was managed in five consecutive patients with vitrectomy and silicone oil injection. The use of silicone oil facilitated anatomic reattachment in three of the five eyes ... Full text Link to item Cite

Relaxing retinotomies. Analysis of anatomic and visual results.

Journal Article Ophthalmology · May 1990 The authors analyzed 100 consecutive eyes undergoing relaxing retinotomies to determine the anatomic and visual results associated with the use of this procedure. With a minimum follow-up of 6 months, 58 eyes were completely attached, 8 were partially atta ... Link to item Cite

Cyanoacrylate tissue adhesive in the management of recurrent retinal detachment caused by macular hole.

Journal Article Am J Ophthalmol · January 15, 1990 Nine eyes of nine patients with rhegmatogenous retinal detachment caused by a macular hole were treated by the transvitreal application of cyanoacrylate tissue adhesive to the macular hole. Eight of the nine eyes had previously failed conventional vitreous ... Full text Link to item Cite

A new retractable micromagnet for intraocular foreign body removal.

Journal Article Arch Ophthalmol · December 1989 We have developed a new, self-contained, small-gauge, permanent, rare-earth magnet for use in conjunction with pars plana vitrectomy in the treatment of selected magnetic intraocular foreign bodies. This magnet allows controlled grasping and releasing of t ... Full text Link to item Cite

Procoagulant effects of intraocular sodium hyaluronate (Healon) after phakic diabetic vitrectomy. A prospective, randomized study.

Journal Article Ophthalmology · October 1989 A procoagulant effect was reported previously after injection of 0.50 to 0.75 ml of sodium hyaluronate (Healon) into the vitreous cavity at the end of phakic diabetic vitrectomies. A multicenter, randomized, prospective trial was done to study this effect. ... Full text Link to item Cite

Results of silicone oil removal in advanced proliferative vitreoretinopathy.

Journal Article Am J Ophthalmol · July 15, 1989 We reviewed the results of silicone oil removal after vitreous surgery for recurrent retinal detachment with proliferative vitreoretinopathy in 55 eyes. The minimum follow-up period was six months. Retinal detachment recurred in five eyes (9%). Evidence of ... Full text Link to item Cite

Surgical management of retinal traction caused by toxocariasis.

Journal Article Am J Ophthalmol · July 15, 1989 We reviewed the results of vitreous surgery in 12 eyes of 12 patients with tractional macular detachment from Toxocara canis. We performed a vitrectomy and membrane peeling in all eyes, with additional scleral buckling in four eyes. After a minimum of six ... Full text Link to item Cite

Temporary iris fixation with a micro-iris retractor.

Journal Article Arch Ophthalmol · June 1989 We developed a new micro-iris retractor to achieve temporary intraoperative pupillary mydriasis in selected eyes undergoing pars plana vitreous surgery. The micro-iris retractor and its use were compared with previous methods for obtaining adequate intraop ... Full text Link to item Cite

An automated aspirating-backflush system for fluid-gas exchange and retinal manipulation.

Journal Article Arch Ophthalmol · June 1989 We have designed a new instrument for use in fluid-gas exchange and retinal manipulation that combines automated aspiration with reflux capabilities. Reflux capability further reduces trauma to the retina when performing procedures using active linear aspi ... Full text Link to item Cite

Classification of proliferative vitreoretinopathy used in the silicone study. The Silicone Study Group.

Journal Article Ophthalmology · June 1989 The Silicone Study is a multicenter randomized clinical trial that compares a long-acting gas with silicone oil for the surgical treatment of proliferative vitreoretinopathy (PVR). As part of the study, a topographic classification of PVR has been develope ... Full text Link to item Cite

Silicone oil injection after failed primary vitreous surgery in severe ocular trauma.

Journal Article Am J Ophthalmol · May 15, 1989 In 42 cases of complicated retinal detachment following trauma after failed primary vitrectomy, at six months follow-up anatomic retinal reattachment posterior to the scleral buckle was achieved in 20 of 40 eyes (50%). Of the 40 eyes, 11 (28%) had a visual ... Full text Link to item Cite

Silicone oil for progressive anterior ocular neovascularization after failed diabetic vitrectomy.

Journal Article Arch Ophthalmol · May 1989 We have performed revision of vitrectomy and silicone oil injection in 18 eyes that developed advanced iris neovascularization and/or anterior hyaloidal fibrovascular proliferation complicated by retinal detachment or media opacity after vitreous surgery f ... Full text Link to item Cite

The validity and reliability of photographic documentation of proliferative vitreoretinopathy.

Journal Article Ophthalmology · March 1989 The Silicone Study is a multicentered, randomized surgical trial designed to compare the tamponade effectiveness of silicone oil versus long-acting gas in the treatment of proliferative vitreoretinopathy (PVR) by vitrectomy and associated techniques. Fundu ... Full text Link to item Cite

Management of anterior vitreous traction in proliferative vitreoretinopathy.

Journal Article Retina · 1989 The major cause of failure in retinal detachment surgery is proliferative vitreoretinopathy. The surgical treatment of proliferative vitreoretinopathy has improved dramatically over the past ten years. Still failure is too common and the need for reoperati ... Full text Link to item Cite

Intraocular pressure following intravitreal silicone oil injection.

Journal Article Ophthalmic Surg · August 1988 The clinical features of 100 consecutive cases and the histopathology of six enucleated eyes, all having undergone silicone oil injection for complicated retinal detachments, were studied with regard to the incidence and mechanisms of postoperative intraoc ... Link to item Cite

Refractive changes from use of silicone oil in vitreous surgery.

Journal Article Retina · 1988 When silicone oil fills the vitreous cavity of the phakic eye or the entire aphakic eye, the refractive correction can be expected to change by 5-9 diopters and sometimes as much as 14 diopters. Aphakic eyes become less hyperopic when filled with silicone ... Full text Link to item Cite

Retinal toxicity of cyanoacrylate tissue adhesive in the rabbit.

Journal Article Retina · 1988 N-butyl-2-cyanoacrylate tissue adhesive was injected into the preretinal space of rabbit eyes to study potential toxicity to the retina. Application of 3.3-10.0 ul of cyanoacrylate tissue adhesive showed localized but definite retinal toxicity. White halos ... Full text Link to item Cite

Transvitreal cyanoacrylate retinopexy in the management of complicated retinal detachment.

Journal Article Am J Ophthalmol · August 15, 1987 We used transvitreally delivered cyanoacrylate tissue adhesive to seal retinal breaks in 25 selected patients undergoing vitreous surgery for complicated retinal detachment. With a minimum follow-up period of six months, all but one retinal hole remained c ... Full text Link to item Cite

Experimental transvitreal cyanoacrylate retinopexy in a primate model.

Journal Article Am J Ophthalmol · June 15, 1987 We evaluated the use of transvitreal cyanoacrylate retinopexy in the treatment of experimental rhegmatogenous retinal detachment during vitreous surgery in the cynomolgus monkey. The chorioretinal adhesions produced with cyanoacrylate tissue adhesive as co ... Full text Link to item Cite

Mechanical retinal fixation using tacks.

Journal Article Ophthalmology · April 1987 Since their introduction, retinal tacks have been increasingly used as an adjunct in the repair of complicated retinal detachments. Indications, results, and complications in a consecutive series of patients undergoing surgery for complicated retinal detac ... Full text Link to item Cite

Long-term results of successful vitrectomy with silicone oil for advanced proliferative vitreoretinopathy.

Journal Article Am J Ophthalmol · January 15, 1987 We have analyzed the six-month, one-year, and two-year follow-up examinations in 47 patients who had silicone oil injection in combination with revision of vitrectomy for intractable retinal detachment and advanced proliferative vitreoretinopathy. A visual ... Full text Link to item Cite

Transvitreal cyanoacrylate retinopexy in the management of complicated retinal detachment.

Journal Article Trans Am Ophthalmol Soc · 1987 Failures in vitreous surgery for complex vitreoretinal disorders are frequently due to an inability to keep preexisting or iatrogenic retinal breaks permanently closed. We have used transvitreally delivered cyanoacrylate tissue adhesive to seal retinal bre ... Link to item Cite

Experimental transvitreal cyanoacrylate retinopexy through silicone oil.

Journal Article Am J Ophthalmol · December 15, 1986 We evaluated the use of transvitreal cyanoacrylate retinopexy in the treatment of experimental rhegmatogenous retinal detachment during vitreous surgery in rabbit eyes filled with silicone oil. The view to the fundus was superior to that obtained in our pr ... Full text Link to item Cite

Endophthalmitis in a silicone oil-filled eye.

Journal Article Am J Ophthalmol · November 15, 1986 Full text Link to item Cite

Experimental transvitreal cyanoacrylate retinopexy.

Journal Article Am J Ophthalmol · August 15, 1986 We used an experimental rabbit model of rhegmatogenous retinal detachment to compare the onset, quality, and duration of chorioretinal adhesions obtained by transvitreal application of N-butyl-2-cyanoacrylate mixed with iophendylate with those obtained by ... Full text Link to item Cite

The use of retinal tacks in the repair of complicated retinal detachments.

Journal Article Am J Ophthalmol · July 15, 1986 Retinal tacks that can be easily placed and removed allow precise intraocular control of retinal fixation in the repair of complicated retinal detachments. We used this technique in 41 consecutive cases of complicated retinal detachment. In 37 cases follow ... Full text Link to item Cite

Relaxing retinotomies and retinectomies.

Journal Article Am J Ophthalmol · July 15, 1986 Relaxing retinotomies and retinectomies are helpful surgical techniques in the treatment of severe cases of retinal detachment with incarcerated retinas, retinal shrinkage caused by proliferative vitreoretinopathy, proliferative vasculopathies, or injury a ... Full text Link to item Cite

Silicone oil for retinal detachment with advanced proliferative vitreoretinopathy following failed vitrectomy for proliferative diabetic retinopathy.

Journal Article Am J Ophthalmol · February 15, 1986 We used sophisticated vitreous surgical techniques in conjunction with silicone oil injection in ten eyes of ten patients with rhegmatogenous retinal detachment complicated by advanced proliferative vitreoretinopathy following failed vitrectomy for prolife ... Full text Link to item Cite

Ultrasonic examination of the silicone-filled eye: theoretical and practical considerations.

Journal Article Graefes Arch Clin Exp Ophthalmol · 1986 As the use of silicone oil in the treatment of complex retinal detachment becomes more frequent, an accurate assessment of ocular structures in these eyes by ultrasonic imaging is increasingly important. Because of the ultrasonic properties of silicone oil ... Full text Link to item Cite

The use of silicone oil following failed vitrectomy for retinal detachment with advanced proliferative vitreoretinopathy.

Journal Article Graefes Arch Clin Exp Ophthalmol · 1986 We have used silicone-oil injection in a consecutive series of 44 patients with retinal detachment and advanced proliferative vitreoretinopathy, all of whom had previously failed to reattach with vitrectomy, membrane peeling, and scleral buckling. After a ... Full text Link to item Cite

The use of silicone oil following failed vitrectomy for retinal detachment with advanced proliferative vitreoretinopathy.

Journal Article Ophthalmology · August 1985 We have used silicone oil injection in a consecutive series of 44 patients with retinal detachment and advanced proliferative vitreoretinopathy, all of whom had previously failed to reattach with vitrectomy, membrane peeling, and scleral buckling. After a ... Full text Link to item Cite

Silicone oil in vitreoretinal surgery. Part 2: Results and complications.

Journal Article Retina · 1985 The surgical results and postoperative complications associated with silicone oil injection in the treatment of complicated retinal detachment were evaluated in a series of 164 eyes followed for a minimum of 6 months. The incidence of recurrent retinal det ... Full text Link to item Cite

Silicone oil in vitreoretinal surgery. Part 1: Surgical techniques.

Journal Article Retina · 1985 The use of silicone oil in the management of intractable retinal detachment associated with proliferative vitreoretinopathy is increasing. Based on clinical experience in over 240 cases, the authors describe their current surgical techniques involving sili ... Full text Link to item Cite

Current views on giant retinal tears

Journal Article Pakistan Journal of Ophthalmology · January 1, 1985 Cite

Controlled aspiration of subretinal fluid in the diagnosis of carcinoma metastatic to the choroid.

Journal Article Arch Ophthalmol · November 1984 Carcinoma metastatic to the choroid was diagnosed in three patients by cytopathologic examination of subretinal fluid. The specimen was obtained using a scleral depressor modified to allow controlled aspiration of subretinal fluid through a sharp, angled, ... Full text Link to item Cite

The pic-forceps for removal of epiretinal membranes.

Journal Article Am J Ophthalmol · October 15, 1984 Full text Link to item Cite

Rubeosis iridis: preoperative iris fluorescein angiography and periocular steroids.

Journal Article Ophthalmology · April 1984 To study the risk of developing rubeosis iridis following vitrectomy, the use of preoperative iris fluorescein angiography was prospectively investigated on patients with diabetes mellitus, without any clinically detectable iris or angle neovascularization ... Full text Link to item Cite

Automated fluid-gas exchange.

Journal Article Am J Ophthalmol · May 1983 Full text Link to item Cite

"Doughnut" bimanual bipolar diathermy electrodes.

Journal Article Am J Ophthalmol · April 1983 Full text Link to item Cite

Toxicity of Triamcinolone Acetonide: Reply

Journal Article American Journal of Ophthalmology · October 1981 Full text Cite

The lack of toxicity of intravitreally administered triamcinolone acetonide.

Journal Article Am J Ophthalmol · June 1981 We gave one eye of each 21 rabbits an intravitreal injection of 1 mg of triamcinolone acetonide; the other eye received an injection of an equal volume of saline solution as a control. Results of slit-lamp examinations, ophthalmoscopy, intraocular pressure ... Full text Link to item Cite

Glucocorticosteroid inhibition of intraocular proliferation after injury.

Journal Article Am J Ophthalmol · February 1981 Perforating injuries were produced in the posterior segment of rabbit eyes. We studied the inhibitory effect of a slowly water-soluble corticosteroid, dexamethasone alcohol, on fibroblast growth. The treated group received a single intravitreal injection o ... Full text Link to item Cite

The role of vitrectomy instrumentation in the treatment of severe traumatic hyphema.

Journal Article Am J Ophthalmol · November 1979 Eight patients with severe traumatic hyphemas underwent clot evacuation with vitrectomy instrumentation. The patients were followed up for periods of one to four years. No significant intraoperative complications were noted, but one eye developed a postope ... Full text Link to item Cite