Overview
As a trained B cell immunologist I have a strong interest in understanding how the adaptive immune system functions to help protect its host during infections. However, having recently joined a virology lab that is focused more on the innate immunity side of things, I have become more interested in understanding how the immune system can damage the host during viral infections. I am particularly interested in understanding how we can target both adaptive and innate immune components to help alleviate inflammatory damage caused by viral respiratory infections.
Current Appointments & Affiliations
Research Scholar
Molecular Genetics and Microbiology,
Basic Science Departments
Recent Publications
B cell-expressed CD1d promotes MPL/TDCM lipid emulsion adjuvant effects in polysaccharide vaccines.
Journal Article Journal of immunology (Baltimore, Md. : 1950) · April 2025 T cell-independent type 2 antigens (TI-2 Ags), such as pneumococcal polysaccharides, elicit weak immunoglobulin G (IgG) responses and are refractive to boosting. Overcoming this challenge is critical for improving vaccines. Previously, we demonstrated a li ... Full text CiteFluorescent and bioluminescent bovine H5N1 influenza viruses for evaluation of antiviral interventions.
Journal Article Journal of virology · November 2024 In early 2024, a clade 2.3.4.4b high pathogenic H5N1 avian influenza virus was detected in dairy cows and humans in the United States. Since then, it has spread to herds in at least 13 states and caused symptomatic disease in at least fifteen people. To fa ... Full text CiteVaccination with antigenically complex hemagglutinin mixtures confers broad protection from influenza disease.
Journal Article Sci Transl Med · May 2024 Current seasonal influenza virus vaccines induce responses primarily against immunodominant but highly plastic epitopes in the globular head of the hemagglutinin (HA) glycoprotein. Because of viral antigenic drift at these sites, vaccines need to be update ... Full text Link to item CiteRecent Grants
ETS-family Transcription Factor Mediated Control of Pulmonary Inflammation Induced by Influenza Viruses
ResearchPostdoctoral Associate · Awarded by National Institute of Allergy and Infectious Diseases · 2023 - 2028Control of virus induced type I interferon signaling during pregnancy
ResearchPostdoctoral Associate · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2027CIVICS Component A - Option 5
ResearchPostdoctoral Associate · Awarded by National Institutes of Health · 2019 - 2025View All Grants