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Michael Lucas James

Professor of Anesthesiology
Anesthesiology, Neuroanesthesia
Box 3094 Med Ctr, Durham, NC 27710
5619D HAFS Building, Durham, NC 27710

Selected Grants


Mid-Atlantic praGmatic NETwork for Inclusive Clinical trials in emergency care (MAGNETIC)

ResearchCo-Principal Investigator · Awarded by National Institute of Neurological Disorders and Stroke · 2023 - 2028

CN105 improves surrogate and functional outcomes after intracerebral hemorrhage (Subaward to AegisCN)

ResearchPrincipal Investigator · Awarded by AegisCN LLC · 2024 - 2026

Brain Oxygen Optimization in Severe Traumatic Brain Injury (BOOST-3)

Clinical TrialPrincipal Investigator · Awarded by University of Michigan · 2019 - 2025

BREEZE: New Ventricular Direct Cooling Stylet to Mitigate Secondary Brain Injury

ResearchCo Investigator · Awarded by National Institutes of Health · 2022 - 2025

Brain Computed Tomography Repository

Clinical TrialPrincipal Investigator · Awarded by AegisCN LLC · 2023 - 2024

USE OF THE NON-INVASIVE, TIME-VARYING BRAINSTEM STIMULATOR IN PATIENTS WITH IMPAIRED CONSCIOUSNESS: A SAFETY AND FEASIBILITY STUDY

Clinical TrialPrincipal Investigator · Awarded by Scion NeuroStim LLC · 2022 - 2024

Recovery and Outcome from StrokE (ROSE) (ICH Recovery Grant)

ResearchPrincipal Investigator · Awarded by University of Cincinnati · 2017 - 2023

Intrepid- BMD-1111

Clinical TrialPrincipal Investigator · Awarded by Bard Medical Division · 2017 - 2023

NICO BrainPath Intracerebral Hemorrhage Evacuation Sample Analysis

ResearchPrincipal Investigator · Awarded by NICO Corporation · 2017 - 2022

CN-105 Study

Clinical TrialPrincipal Investigator · Awarded by AegisCN LLC · 2016 - 2021

SETPOINT 2: A pragmatic trial to test the effectiveness of early vs. delayed percutaneous tracheostomy in patients with severe stroke and respiratory failure.

Clinical TrialPrincipal Investigator · Awarded by Maine Medical Center Research Institute · 2017 - 2021

Genetic and Environmental Risk Factors for Hemorrhagic Stroke

ResearchPrincipal Investigator · Awarded by University of Cincinnati · 2017 - 2020

Novartis Phase II BAF312 in Stroke ICH

Clinical TrialPrincipal Investigator · Awarded by Novartis Pharmaceuticals Corporation · 2018 - 2020

CN105 to improve long-term recovery in models of intracerebral hemorrhage

ResearchPrincipal Investigator · Awarded by AegisCN LLC · 2018 - 2020

Futility study of Deferoxamine Mesylate in Intracerebral Hemorrhage (i-Def)

Clinical TrialPrincipal Investigator · Awarded by Beth Israel Deaconess Medical Center · 2012 - 2019

Dova Avatrombopag for Thrombocytopenia

Clinical TrialPrincipal Investigator · Awarded by DOVA Pharmaceuticals · 2018 - 2019

Xenon As A Therapeutic in Experimental Intracerebral Hemorrhage

ResearchCo Investigator · Awarded by National Institutes of Health · 2015 - 2018

Cephalogics DOT 3.0 in Cerebral Vasospasm

ResearchPrincipal Investigator · Awarded by Cephalogics, LLC · 2016 - 2017

External Relationships


  • Duke-NUS Medical school

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.