Scholars@Duke
Michelle Marie Genvieve Elisabeth Schneider

Michelle Marie Genvieve Elisabeth Schneider

Assistant Professor of Pathology
Pathology
michelle.schneider@duke.edu
40 Duke Medicine Circle, Durham, NC 27710
40 Duke Medicine Circle, Durham, NC 27710

Selected Publications

PRAME Immunohistochemistry for Differentiating Pigmented Lesions of the Vulva and Perineum.

Journal Article J Cutan Pathol · October 2025 Special site pigmented lesions often present a diagnostic challenge for clinicians and for pathologists. Lesions of the genital region present even further challenges due to the sensitivity of the anatomic location and preference to defer physical exam and ... Full text Link to item Cite

A Comparative Study Between Copy Number Alterations and PRAME Immunohistochemical Pilot Study in Challenging Melanocytic Lesions.

Journal Article Cancers (Basel) · April 4, 2025 INTRODUCTION: Diagnostic uncertainty for ambiguous lesions that fall on the spectrum between nevi and melanoma remains a significant challenge and can have consequences for patient management. METHODS: This study aimed to compare the diagnostic utility of ... Full text Link to item Cite

COVID-19 Vaccination as a Precipitating Factor in Cutaneous Lupus Erythematosus with Lupus Nephritis: A Clinical Case Report

Journal Article Skin Journal of Cutaneous Medicine · March 1, 2025 The advent of the COVID-19 vaccine has improved global mortality, but recent literature suggests that COVID-19 vaccinations may induce or exacerbate autoimmune rheumatic diseases. Here, we present a 64-year-old woman with a history of Evans syndrome, perni ... Full text Cite

An etiology-focused overview of vulvar and penile squamous cell carcinoma and its precursors: similarities, differences and emerging concepts

Journal Article Diagnostic Histopathology · January 1, 2024 Although rare, cancer of the vulva and penis have significant morbidity, mortality, and potentially psychologically distressing treatments. At both sites, squamous cell carcinoma (SCC) is the most common tumor type. Transitioning from classification system ... Full text Cite

Pediatric Atypical Melanocytic Proliferations: Single-Site Retrospective Cohort Assessment of Treatment and Long-Term Follow-Up.

Journal Article Cancers (Basel) · December 12, 2023 Atypical and malignant cutaneous tumors are understudied in the pediatric population, with limited data on long-term follow-up. This study examines pediatric (0-18 years) atypical melanocytic proliferations over a twenty-year period (January 2002-December2 ... Full text Link to item Cite

Exploring the Role of Spatial Confinement in Immune Cell Recruitment and Regeneration of Skin Wounds.

Journal Article Adv Mater · December 2023 Microporous annealed particle (MAP) scaffolds are injectable granular materials comprised of micron sized hydrogel particles (microgels). The diameter of these microgels directly determines the size of the interconnected void space between particles where ... Full text Link to item Cite

A Balance between Pro-Inflammatory and Pro-Reparative Macrophages is Observed in Regenerative D-MAPS.

Journal Article Adv Sci (Weinh) · April 2023 Microporous annealed particle scaffolds (MAPS) are a new class of granular materials generated through the interlinking of tunable microgels, which produce an interconnected network of void space. These microgel building blocks can be designed with differe ... Full text Open Access Link to item Cite

Severe Retiform Purpura Associated With COVID-19 Infection

Journal Article Annals of Internal Medicine Clinical Cases · April 1, 2022 A healthy, unvaccinated 44-year-old woman developed a severe, diffusely spread, and intensely painful purpuric rash following mild COVID-19 infection. A punch skin biopsy revealed small vessel inflammation and intravascular thrombi consistent with thrombot ... Full text Cite

Prediction of Neutropenic Events in Chemotherapy Patients: A Machine Learning Approach.

Journal Article JCO Clin Cancer Inform · August 2021 PURPOSE: Severe and febrile neutropenia present serious hazards to patients with cancer undergoing chemotherapy. We seek to develop a machine learning-based neutropenia prediction model that can be used to assess risk at the initiation of a chemotherapy cy ... Full text Link to item Cite

The Clinical Spectrum of Primary Cutaneous CD4+ Small/Medium-Sized Pleomorphic T-Cell Lymphoproliferative Disorder: An Updated Systematic Literature Review and Case Series.

Journal Article Dermatology · 2021 BACKGROUND: Primary cutaneous CD4+ small/medium pleomorphic T-cell lymphoproliferative disorder (SMPLPD) is a provisional entity within the 2016 World Health Organization classification of primary cutaneous lymphomas. The condition is currently classified ... Full text Link to item Cite

COVID-19 mortality risk assessment: An international multi-center study.

Journal Article PLoS One · 2020 Timely identification of COVID-19 patients at high risk of mortality can significantly improve patient management and resource allocation within hospitals. This study seeks to develop and validate a data-driven personalized mortality risk calculator for ho ... Full text Link to item Cite

Severe skin disease in lupus associated with hemophagocytic lymphohistiocytosis: Case reports and review of the literature

Journal Article BMC Rheumatology · January 1, 2019 Background: Hemophagocytic lymphohistiocytosis (HLH) is a severe clinical entity associated with high mortality in the adult population. HLH has been associated with infections, malignancy and autoimmune conditions such as Systemic Lupus Erythematosus (SLE ... Full text Cite

Amicrobial Pustulosis of the Folds and Autoimmunity.

Journal Article J Low Genit Tract Dis · October 2016 Full text Link to item Cite

Vascularized composite allotransplantation: a closer look at the banff working classification.

Journal Article Transpl Int · June 2016 The first Banff vascularized composite allotransplantation meeting was held in 2007 to standardize criteria for the characterization and reporting of severity and types of rejection. As a result, the 2007 Banff VCA working classification for skin allograft ... Full text Link to item Cite

Sentinel lymph node biopsy following a rotational flap.

Journal Article BMJ Case Rep · July 14, 2015 Sentinel lymph node biopsy (SLNB) is a critical component of melanoma management. Extensive prior surgery at the site of a primary melanoma is considered a relative contraindication for SLNB. While evidence suggests that SLNB may be performed accurately ev ... Full text Link to item Cite