Journal ArticleBMJ Open Diabetes Res Care · February 27, 2024
INTRODUCTION: Severe hypoglycemia (SH) in older adults (OAs) with type 1 diabetes is associated with profound morbidity and mortality, yet its etiology can be complex and multifactorial. Enhanced tools to identify OAs who are at high risk for SH are needed ...
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Journal ArticleBiometrics · January 29, 2024
Precision medicine is a promising framework for generating evidence to improve health and health care. Yet, a gap persists between the ever-growing number of statistical precision medicine strategies for evidence generation and implementation in real-world ...
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Journal ArticleSyst Rev · January 22, 2024
BACKGROUND: Systematic reviews of observational studies can be affected by biases that lead to under- or over-estimates of true intervention effects. Several tools have been reported in the literature that attempt to characterize potential bias. Our object ...
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ConferenceJ Vasc Surg Venous Lymphat Disord · November 2023
Weak evidence, when manifested in clinical guidelines, can translate into biased vascular care. In vascular surgery, we have few randomized controlled trials with appropriate representation of females and persons of color, so generalizability of trial resu ...
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Journal ArticleJ Am Geriatr Soc · February 2023
Older adults are characterized by profound clinical heterogeneity. When designing and delivering interventions, there exist multiple approaches to account for heterogeneity. We present the results of a systematic review of data-driven, personalized interve ...
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Journal ArticleWound Repair Regen · 2023
Chronic limb-threatening ischemia (CLTI) is associated with significant morbidity, including major limb amputation, and mortality. Healing ischemic wounds is necessary to optimise vascular outcomes and can be facilitated by dedicated appointments at a woun ...
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Journal ArticleSemin Vasc Surg · December 2022
Randomized controlled trials (RCTs) are widely considered to provide the highest-quality evidence for the comparative efficacy and safety of competing clinical strategies. The strength of using RCTs for causal inference is derived from random treatment ass ...
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Journal ArticleJAMA Netw Open · March 1, 2022
IMPORTANCE: Valid risk stratification schemes are key to performing comparative effectiveness research; however, for chronic limb-threatening ischemia (CLTI), risk stratification schemes have limited efficacy. Improved, accurate, comprehensive, and reprodu ...
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Journal ArticleSociol Health Illn · March 2022
While the effects of social stratification by gender, race, class, and ethnicity on health inequalities are well-documented, our understanding of the intersecting consequences of these social dimensions on diagnosis remains limited. This is particularly th ...
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Journal ArticleAnn Vasc Surg · January 2022
BACKGROUND: To set therapeutic benchmarks, in 2009 the Society for Vascular Surgery defined objective performance goals (OPG) for treatment of patients with chronic limb threatening ischemia (CLTI) with either open surgical bypass or endovascular intervent ...
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Journal ArticleGates Open Res · 2022
Background: Each year, nearly 300,000 women and 5 million fetuses or neonates die during childbirth or shortly thereafter, a burden concentrated disproportionately in low- and middle-income countries. Identifying women and their fetuses at risk for intrapa ...
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Journal ArticleObs Stud · July 2021
In the twenty years since Dr. Leo Breiman's incendiary paper Statistical Modeling: The Two Cultures was first published, algorithmic modeling techniques have gone from controversial to commonplace in the statistical community. While the widespread adoption ...
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Journal ArticleFront Cardiovasc Med · 2021
Introduction: In cancer, there are survival-based staging systems and tailored, stage-based treatments. There is little personalized treatment in vascular disease. The 2019 Global Vascular Guidelines on the Management of CLTI proposed successful treatment ...
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Journal ArticleStatistical Analysis and Data Mining · December 1, 2020
In the applied sciences, the ultimate goal is not just to acquire knowledge but to turn knowledge into action. The next wave for data disciplines may be experimental designs and analytical methods for closing the gap between the “real-world” situations fac ...
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Journal ArticleEGEMS (Wash DC) · August 5, 2019
The results of many large-scale federal or multi-site evaluations are typically compiled into long reports which end up sitting on policymaker's shelves. Moreover, the information policymakers need from these reports is often buried in the report, may not ...
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Journal ArticleJ Vasc Surg · August 2019
BACKGROUND: Patients undergoing vascular operations face high rates of intraoperative and postoperative complications and delayed return to baseline. Enhanced recovery after surgery (ERAS), with its aim of delivering high-quality perioperative care and acc ...
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Journal ArticleObes Rev · April 2018
The effectiveness of bariatric surgery has been well-studied. However, complications after bariatric surgery have been understudied. This review assesses <30-d major complications associated with bariatric procedures, including anastomotic leak, myocardial ...
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Journal ArticleBMJ Open Diabetes Res Care · February 27, 2024
INTRODUCTION: Severe hypoglycemia (SH) in older adults (OAs) with type 1 diabetes is associated with profound morbidity and mortality, yet its etiology can be complex and multifactorial. Enhanced tools to identify OAs who are at high risk for SH are needed ...
Full textLink to itemCite
Journal ArticleBiometrics · January 29, 2024
Precision medicine is a promising framework for generating evidence to improve health and health care. Yet, a gap persists between the ever-growing number of statistical precision medicine strategies for evidence generation and implementation in real-world ...
Full textLink to itemCite
Journal ArticleSyst Rev · January 22, 2024
BACKGROUND: Systematic reviews of observational studies can be affected by biases that lead to under- or over-estimates of true intervention effects. Several tools have been reported in the literature that attempt to characterize potential bias. Our object ...
Full textLink to itemCite
ConferenceJ Vasc Surg Venous Lymphat Disord · November 2023
Weak evidence, when manifested in clinical guidelines, can translate into biased vascular care. In vascular surgery, we have few randomized controlled trials with appropriate representation of females and persons of color, so generalizability of trial resu ...
Full textLink to itemCite
Journal ArticleJ Am Geriatr Soc · February 2023
Older adults are characterized by profound clinical heterogeneity. When designing and delivering interventions, there exist multiple approaches to account for heterogeneity. We present the results of a systematic review of data-driven, personalized interve ...
Full textLink to itemCite
Journal ArticleWound Repair Regen · 2023
Chronic limb-threatening ischemia (CLTI) is associated with significant morbidity, including major limb amputation, and mortality. Healing ischemic wounds is necessary to optimise vascular outcomes and can be facilitated by dedicated appointments at a woun ...
Full textLink to itemCite
Journal ArticleSemin Vasc Surg · December 2022
Randomized controlled trials (RCTs) are widely considered to provide the highest-quality evidence for the comparative efficacy and safety of competing clinical strategies. The strength of using RCTs for causal inference is derived from random treatment ass ...
Full textLink to itemCite
Journal ArticleJAMA Netw Open · March 1, 2022
IMPORTANCE: Valid risk stratification schemes are key to performing comparative effectiveness research; however, for chronic limb-threatening ischemia (CLTI), risk stratification schemes have limited efficacy. Improved, accurate, comprehensive, and reprodu ...
Full textLink to itemCite
Journal ArticleSociol Health Illn · March 2022
While the effects of social stratification by gender, race, class, and ethnicity on health inequalities are well-documented, our understanding of the intersecting consequences of these social dimensions on diagnosis remains limited. This is particularly th ...
Full textLink to itemCite
Journal ArticleAnn Vasc Surg · January 2022
BACKGROUND: To set therapeutic benchmarks, in 2009 the Society for Vascular Surgery defined objective performance goals (OPG) for treatment of patients with chronic limb threatening ischemia (CLTI) with either open surgical bypass or endovascular intervent ...
Full textLink to itemCite
Journal ArticleGates Open Res · 2022
Background: Each year, nearly 300,000 women and 5 million fetuses or neonates die during childbirth or shortly thereafter, a burden concentrated disproportionately in low- and middle-income countries. Identifying women and their fetuses at risk for intrapa ...
Full textLink to itemCite
Journal ArticleObs Stud · July 2021
In the twenty years since Dr. Leo Breiman's incendiary paper Statistical Modeling: The Two Cultures was first published, algorithmic modeling techniques have gone from controversial to commonplace in the statistical community. While the widespread adoption ...
Full textLink to itemCite
Journal ArticleFront Cardiovasc Med · 2021
Introduction: In cancer, there are survival-based staging systems and tailored, stage-based treatments. There is little personalized treatment in vascular disease. The 2019 Global Vascular Guidelines on the Management of CLTI proposed successful treatment ...
Full textLink to itemCite
Journal ArticleStatistical Analysis and Data Mining · December 1, 2020
In the applied sciences, the ultimate goal is not just to acquire knowledge but to turn knowledge into action. The next wave for data disciplines may be experimental designs and analytical methods for closing the gap between the “real-world” situations fac ...
Full textCite
Journal ArticleEGEMS (Wash DC) · August 5, 2019
The results of many large-scale federal or multi-site evaluations are typically compiled into long reports which end up sitting on policymaker's shelves. Moreover, the information policymakers need from these reports is often buried in the report, may not ...
Full textLink to itemCite
Journal ArticleJ Vasc Surg · August 2019
BACKGROUND: Patients undergoing vascular operations face high rates of intraoperative and postoperative complications and delayed return to baseline. Enhanced recovery after surgery (ERAS), with its aim of delivering high-quality perioperative care and acc ...
Full textLink to itemCite
Journal ArticleObes Rev · April 2018
The effectiveness of bariatric surgery has been well-studied. However, complications after bariatric surgery have been understudied. This review assesses <30-d major complications associated with bariatric procedures, including anastomotic leak, myocardial ...
Full textLink to itemCite
Journal ArticleHealth Aff (Millwood) · March 1, 2017
Using delivery system innovations to advance health care reform continues to be of widespread interest. However, it is difficult to generalize about the success of specific types of innovations, since they have been examined in only a few studies. To gain ...
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Journal ArticleSubst Abuse · 2017
Substance users are more likely to have co-occurring health problems, and this pattern is intensified among those involved with the criminal justice system. Interview data for 1977 incarcerated men in 5 states from the Multi-site Family Study on Incarcerat ...
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