Journal ArticleJ Surg Res · November 16, 2024
INTRODUCTION: Racial and ethnic disparities in malnutrition are well-known, but it is unknown if there are disparities in early nutrition delivery for intensive care unit (ICU) patients, which is associated with better outcomes. We investigated the timing ...
Full textLink to itemCite
Journal ArticlePediatrics · September 1, 2024
BACKGROUND AND OBJECTIVES: Place-based social disadvantage indices are increasingly used to promote health equity, but vary in design. We compared associations between 3 commonly used indices (Social Vulnerability Index [SVI], Area Deprivation Index [ADI], ...
Full textLink to itemCite
Journal ArticleEur Urol Open Sci · August 2024
INTRODUCTION AND HYPOTHESES: The Outcomes Database to prospectivelY aSSEss the changing TherapY landscape in Renal Cell Carcinoma (ODYSSEY RCC) Registry is a large, nationally representative prospective registry of patients with metastatic renal cell carci ...
Full textLink to itemCite
Journal ArticleSci Data · May 24, 2024
Pulse oximeters measure peripheral arterial oxygen saturation (SpO2) noninvasively, while the gold standard (SaO2) involves arterial blood gas measurement. There are known racial and ethnic disparities in their performance. BOLD is a dataset that aims to u ...
Full textLink to itemCite
Journal ArticleJ Clin Transl Sci · 2024
OBJECTIVE: Type 2 diabetes (T2DM) poses a significant public health challenge, with pronounced disparities in control and outcomes. Social determinants of health (SDoH) significantly contribute to these disparities, affecting healthcare access, neighborhoo ...
Full textLink to itemCite
Journal ArticleJ Clin Transl Sci · 2024
Multisector stakeholders, including, community-based organizations, health systems, researchers, policymakers, and commerce, increasingly seek to address health inequities that persist due to structural racism. They require accessible tools to visualize an ...
Full textLink to itemCite
Journal ArticleCurrent Transplantation Reports · January 1, 2024
Purpose of Review: This paper summarizes predictive models developed to determine transplant eligibility over the past 5 years, focusing on application of novel data sources and methodologic approaches. Recent Findings: The contemporary body of research em ...
Full textCite
Journal ArticleJAMIA Open · December 2023
INTRODUCTION: Gun violence remains a concerning and persistent issue in our country. Novel dashboards may integrate and summarize important clinical and non-clinical data that can inform targeted interventions to address the underlying causes of gun violen ...
Full textLink to itemCite
Journal ArticleJAMA Netw Open · December 1, 2023
IMPORTANCE: Studies elucidating determinants of residential neighborhood-level health inequities are needed. OBJECTIVE: To quantify associations of structural racism indicators with neighborhood prevalence of chronic kidney disease (CKD), diabetes, and hyp ...
Full textLink to itemCite
Journal ArticlemedRxiv · October 3, 2023
Pulse oximeters measure peripheral arterial oxygen saturation (SpO 2 ) noninvasively, while the gold standard (SaO 2 ) involves arterial blood gas measurement. There are known racial and ethnic disparities in their performance. BOLD is a new comprehensive ...
Full textLink to itemCite
Journal ArticleArthroplast Today · October 2023
BACKGROUND: Physical function and pain outcomes vary after arthroplasty. We investigated differences in postoperative Patient-Reported Outcomes Measurement Information System (PROMIS) physical function (PF) and pain interference (PI) scores for patients un ...
Full textLink to itemCite
Journal ArticleAm J Transplant · March 2023
The choice of deprivation index can influence conclusions drawn regarding the extent of deprivation within a community and the identification of the most deprived communities in the United States. This study aimed to determine the degree of correlation amo ...
Full textLink to itemCite
Journal ArticleJAMA Netw Open · February 1, 2023
IMPORTANCE: Hypertension self-management is recommended for optimal blood pressure (BP) control, but self-identified residential contextual factors that hinder hypertension self-care are understudied. OBJECTIVE: To quantify perceived neighborhood health an ...
Full textLink to itemCite
Journal ArticleJ Urban Health · December 2022
There is tremendous interest in understanding how neighborhoods impact health by linking extant social and environmental drivers of health (SDOH) data with electronic health record (EHR) data. Studies quantifying such associations often use static neighbor ...
Full textLink to itemCite
Journal ArticleMilbank Q · December 2022
UNLABELLED: Policy Points The rapid uptake of disadvantage indices during the pandemic highlights investment in implementing tools that address health equity to inform policy. Existing indices differ in their design, including data elements, social determi ...
Full textLink to itemCite
Journal ArticleAm J Transplant · October 2022
Health equity research in transplantation has largely relied on national data sources, yet the availability of social determinants of health (SDOH) data varies widely among these sources. We sought to characterize the extent to which national data sources ...
Full textLink to itemCite
Journal ArticleJAMA Netw Open · September 1, 2022
IMPORTANCE: System and center-level interventions to improve health equity in organ transplantation benefit from robust characterization of the referral population served by each transplant center. Transplant referral regions (TRRs) define geographic catch ...
Full textLink to itemCite
Journal ArticleJ Pain · March 2022
Hip, knee, and shoulder arthroplasty are among the most frequently performed orthopaedic procedures in the United States. High impact and bothersome chronic pain rates following total joint arthroplasty (TJA) are unknown; as are factors that predict these ...
Full textLink to itemCite
Journal ArticleClin Genitourin Cancer · February 2022
INTRODUCTION: The Metastatic Renal Cell Carcinoma (MaRCC) Registry provides prospective data on real-world treatment patterns and outcomes in patients with metastatic renal cell carcinoma (mRCC). METHODS AND MATERIALS: Patients with mRCC and no prior syste ...
Full textLink to itemCite
Journal ArticleBMC Nephrol · November 11, 2021
BACKGROUND: Individuals with chronic kidney disease (CKD), hypertension (HTN), or diabetes mellitus (DM) are at increased risk for cardiovascular disease (CVD). The extent to which psychosocial factors are associated with increased CVD risk within these in ...
Full textLink to itemCite
Journal ArticleJournal of hypertension · November 2021
BackgroundPoor sleep is associated with increased hypertension risk, but few studies have evaluated multiple sleep dimensions or investigated racial/ethnic disparities in this association among women.MethodWe investigated multiple sleep d ...
Full textCite
Journal ArticlePain Med · August 6, 2021
OBJECTIVE: Musculoskeletal pain conditions are a leading cause of pain and disability internationally and a common reason to seek health care. Accurate prediction of recurrence of health care seeking due to musculoskeletal conditions could allow for better ...
Full textLink to itemCite
Journal ArticleCancer · July 1, 2021
BACKGROUND: Systemic therapy (ST) can be deferred in patients who have metastatic renal cell carcinoma (mRCC) and slow-growing metastases. Currently, this subset of patients managed with active surveillance (AS) is not well described in the literature. MET ...
Full textOpen AccessLink to itemCite
ConferenceCirculation · May 25, 2021
Introduction:
Studies using electronic health record (EHR) data often have a limited number of years available for analysis. There is a trade off between the look back period length used to define bas ...
Full textCite
Journal ArticlePLoS One · 2021
OBJECTIVES: Chronic pain affects 50 million Americans and is often treated with non-pharmacologic approaches like physical therapy. Developing a no-show prediction model for individuals seeking physical therapy care for musculoskeletal conditions has sever ...
Full textOpen AccessLink to itemCite
Journal ArticleKidney Med · 2021
RATIONALE & OBJECTIVE: Digital health system tools to support shared decision making and preparation for kidney replacement treatments for patients with chronic kidney disease (CKD) are needed. STUDY DESIGN: Descriptive study of the implementation of digit ...
Full textLink to itemCite
Journal ArticleWMJ · December 2020
BACKGROUND: Significant weight loss improves health but regain is common. OBJECTIVE: The objective of the study was to determine if 2,346 members of Take Off Pounds Sensibly-a national, low-cost, peer-led weight-loss program-achieved and maintained signifi ...
Link to itemCite
Journal ArticleJ Public Health (Oxf) · November 23, 2020
BACKGROUND: Community health data are infrequently viewed in the context of social and environmental health determinants. We developed a novel data-sharing model to democratize health system data and to facilitate community and population health improvemen ...
Full textLink to itemCite
Journal ArticleRespir Care · September 2020
BACKGROUND: Unanticipated respiratory compromise that lead to unplanned intubations is a known phenomenon in hospitalized patients. Most events occur in patients at high risk in well-monitored units; less is known about the incidence, risk factors, and tra ...
Full textLink to itemCite
Journal ArticleClin J Am Soc Nephrol · March 6, 2020
BACKGROUND AND OBJECTIVES: Low socioeconomic status confers unfavorable health, but the degree and mechanisms by which life course socioeconomic status affects kidney health is unclear. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We examined the associa ...
Full textLink to itemCite
Journal ArticleJ Palliat Med · January 2020
Background: Hospital referral regions (HRRs) are often used to characterize inpatient referral patterns, but it is unknown how well these geographic regions are aligned with variation in Medicare-financed hospice care, which is largely provided at home. Ob ...
Full textLink to itemCite
Journal ArticlePLoS One · 2020
Neighborhoods have a profound impact on individual health. There is growing interest in the role of dynamic changes to neighborhoods-including gentrification-on the health of residents. However, research on the association between gentrification and health ...
Full textLink to itemCite
Journal ArticlePain Rep · 2020
Clinical practice guidelines and the Federal Pain Research Strategy (United States) have recently highlighted research priorities to lessen the public health impact of low back pain (LBP). It may be necessary to improve existing predictive approaches to me ...
Full textOpen AccessLink to itemCite
Journal ArticleAm J Hypertens · September 24, 2019
BACKGROUND: The Dietary Approaches to Stop Hypertension (DASH) diet lowers blood pressure (BP) more effectively in blacks compared to other US racial subgroups. Considering chronic kidney disease (CKD) raises BP through complex mechanisms, DASH may affect ...
Full textLink to itemCite
Journal ArticleBMC Nephrol · July 15, 2019
BACKGROUND: There is limited evidence on the relationship between social support and renal outcomes in African Americans. We sought to determine the association of social support with prevalent chronic kidney disease (CKD) and kidney function decline in an ...
Full textLink to itemCite
Internet Publication · June 1, 2019
BACKGROUND: 25-hydroxyvitamin D [25(OH)D] is lower in black compared with white Americans but is not consistently associated with outcomes in this group, possibly due to genetic and other biological differences. We examined the association of plasma 25(OH) ...
Full textOpen AccessLink to itemCite
Journal ArticleClin J Am Soc Nephrol · April 5, 2019
BACKGROUND AND OBJECTIVES: Many aspects of CKD management rely heavily on patient self-care, including medication and dietary adherence, self-monitoring of BP, and daily physical activity. Growing evidence suggests that incorporating smartphone-based appli ...
Full textLink to itemCite
Journal ArticleBMJ Support Palliat Care · March 2019
OBJECTIVES: We examined public reaction to the proposed Center for Medicare and Medicaid Services rule reimbursing physicians for advanced care planning (ACP) discussions with patients. METHODS: Public comments made on regulations.gov were reviewed for rel ...
Full textLink to itemCite
Journal ArticleKidney Int Rep · March 2019
INTRODUCTION: Poor sleep associates with adverse chronic kidney disease (CKD) outcomes yet the biological mechanisms underlying this relation remain unclear. One proposed mechanism is via allostatic load, a cumulative biologic measure of stress. METHODS: U ...
Full textOpen AccessLink to itemCite
Journal ArticleBMC Nephrol · January 10, 2019
BACKGROUND: Use of routine medical care (RMC) is advocated to address ethnic/racial disparities in chronic kidney disease (CKD) risks, but use is less frequent among African Americans. Factors associated with low RMC use among African Americans at risk of ...
Full textOpen AccessLink to itemCite
Journal ArticleAm J Hypertens · January 1, 2019
BACKGROUND: Higher dietary phosphorus is associated with left ventricular hypertrophy and mortality, which are blood pressure (BP)-related outcomes. For this reason, we hypothesized that dietary phosphorus may be associated with adverse clinic and ambulato ...
Full textLink to itemCite
Journal ArticleCancer Prev Res (Phila) · December 2018
Lipid-lowering medications, particularly statins, may protect against aggressive prostate cancer. Fatal prostate cancer, the most clinically relevant outcome, remains understudied for this association. We prospectively studied lipid-lowering medication use ...
Full textLink to itemCite
Journal ArticleContemp Clin Trials · October 2018
UNLABELLED: Care for patients transitioning from chronic kidney disease to kidney failure often falls short of meeting patients' needs. The PREPARE NOW study is a cluster randomized controlled trial studying the effectiveness of a pragmatic health system i ...
Full textLink to itemCite
Journal ArticleJAMA Netw Open · September 7, 2018
IMPORTANCE: Data from electronic health records (EHRs) are increasingly used for risk prediction. However, EHRs do not reliably collect sociodemographic and neighborhood information, which has been shown to be associated with health. The added contribution ...
Full textLink to itemCite
Journal ArticleJ Palliat Med · August 2018
BACKGROUND: Use of the Medicare hospice benefit has been associated with high-quality care at the end of life, and hospice length of use in particular has been used as a proxy for appropriate timing of hospice enrollment. Quantile regression has been under ...
Full textLink to itemCite
Journal ArticleJMIR Hum Factors · July 16, 2018
BACKGROUND: The US National Cancer Institute (NCI) developed software to gather symptomatic adverse events directly from patients participating in clinical trials. The software administers surveys to patients using items from the Patient-Reported Outcomes ...
Full textLink to itemCite
Journal ArticleNephrol Dial Transplant · June 1, 2018
BACKGROUND: African Americans are at high risk for chronic kidney disease (CKD). Obesity may increase the risk for CKD by exacerbating features of the metabolic syndrome and promoting glomerular hyperfiltration. Whether other factors also affecting these p ...
Full textLink to itemCite
Journal ArticleBMC Urol · May 9, 2018
BACKGROUND: Multiple guidelines seek to alter rates of prostate-specific antigen (PSA)-based prostate cancer screening. The costs borne by payers associated with PSA-based screening for men of different age groups-including the costs of screening and subse ...
Full textLink to itemCite
Journal ArticleJ Palliat Med · May 2018
BACKGROUND: On January 1, 2016, Medicare implemented a new "two-tiered" model for hospice services, with per diem rates increased for days 1 through 60, decreased for days 61 and greater, and service intensity add-on payments made retrospectively for the l ...
Full textLink to itemCite
Journal ArticleClin J Am Soc Nephrol · February 7, 2018
BACKGROUND AND OBJECTIVES: Established risk factors for CKD do not fully account for risk of CKD in black Americans. We studied the association of nondepressive psychosocial factors with risk of CKD in the Jackson Heart Study. DESIGN, SETTING, PARTICIPANTS ...
Full textLink to itemCite
Journal ArticleThe American journal of hospice & palliative care · January 2018
BackgroundThe prevalence of hospital-based palliative care has been largely anecdotal as an increasing service being provided and there is a need to understand what trends can be analyzed with Medicare data.ObjectiveTo compare 2 methods o ...
Full textCite
Journal ArticleEGEMS (Wash DC) · December 6, 2017
Electronic health record (EHR) data are becoming a primary resource for clinical research. Compared to traditional research data, such as those from clinical trials and epidemiologic cohorts, EHR data have a number of appealing characteristics. However, be ...
Full textLink to itemCite
Journal ArticleJ Palliat Med · October 2017
BACKGROUND: Use of palliative care has increased substantially as the population ages and as evidence for its benefits grows. However, there is limited information regarding which care activities are necessary for delivering high-quality, interdisciplinary ...
Full textLink to itemCite
Journal ArticleEGEMS (Wash DC) · June 12, 2017
INTRODUCTION: Self-reporting by patients though the use of electronic patient-reported outcome (PRO) measures has been shown to use increase patient satisfaction with care, and improve patient-provider communication, symptom management, and health quality. ...
Full textLink to itemCite
Journal ArticleCancer Invest · May 28, 2017
The Metastatic Renal Cell Cancer Registry, a large, nationally representative, prospective registry of patients with metastatic renal cell carcinoma (mRCC), aims to understand real-world treatment patterns and outcomes of patients with mRCC in routine clin ...
Full textLink to itemCite
Journal ArticleAm J Epidemiol · December 1, 2016
Electronic health records (EHRs) are an increasingly utilized resource for clinical research. While their size allows for many analytical opportunities, as with most observational data there is also the potential for bias. One of the key sources of bias in ...
Full textLink to itemCite
Journal ArticleInt J Radiat Oncol Biol Phys · September 1, 2016
PURPOSE: Ipilimumab and radiation therapy (RT) are standard treatments for advanced melanoma; preclinical models suggest the potential for synergy. However, limited clinical information exists regarding safety and optimal timing of the combination. METHODS ...
Full textLink to itemCite
ConferenceCancer Research · February 15, 2016
AbstractBackground: Baseline TIL density and T-cell clonality predict pathological complete response (pCR) to neoadjuvant (NA) trastuzumab (TRAS). Preclinical data suggests that a major mechanism of TRAS is ...
Full textCite
ConferenceJournal of Clinical Oncology · January 10, 2016
563 Background: Clinical trials mRCC pts are different from real world pts, resulting in bias in the literature. The MaRCC Registry is designed to survey questions not asked in tri als, such as why physicians make certain managem ...
Full textCite
ConferenceJournal of Clinical Oncology · January 10, 2016
617 Background: Over the past decade, seven agents were approved for metastatic renal cell carcinoma (mRCC) leading to a rapidly evolving clinical landscape. Clinical trials addressing treatment efficacy, sequencing, and other qu ...
Full textCite
ConferenceCancer · January 15, 2015
BACKGROUND: The Cancer and Leukemia Group B (CALGB) 9343 randomized phase 3 trial established lumpectomy and adjuvant therapy with tamoxifen alone, rather than both radiotherapy and tamoxifen, as a reasonable treatment course for women aged >70 years with ...
Full textLink to itemCite
Journal ArticleCancer Epidemiol Biomarkers Prev · November 2014
BACKGROUND: TH1 cytokines, such as IFNγ and TNFα, and potentially innate cytokines, such as IL6, can potentiate the immune response to tumor. Cytokines, such as IL1β, IL8, and IL10, may suppress anticancer immunity. Thus, we prospectively evaluated the ass ...
Full textLink to itemCite
Journal ArticleJ Clin Oncol · October 20, 2014
281 Background: Surgical quality measures look to reduce variation and improve outcomes. Procedure goals can range from cure to symptom improvement. Knowledge of procedures used in this population can inform quality metrics, ensure palliation is included a ...
Full textLink to itemCite
Journal ArticleBJU Int · April 2014
OBJECTIVE: To investigate the association between serum prostate-specific antigen (PSA) concentration at active surveillance (AS) entry and disease reclassification on subsequent AS biopsy ('biopsy reclassification') in men with low PSA density (PSAD). To ...
Full textLink to itemCite
Journal ArticleCancer · November 15, 2012
BACKGROUND: Clinical guidelines recommend against routine prostate-specific antigen (PSA) screening for older men and for those with lower life expectancies. The authors of this report examined providers' decision-making regarding discontinuing PSA screeni ...
Full textLink to itemCite
Journal ArticleAm J Kidney Dis · August 2012
BACKGROUND: Identifying individuals at risk of chronic kidney disease (CKD) is critical for timely treatment initiation to slow progression of the disease. Neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule 1 (KIM-1) are known bio ...
Full textLink to itemCite
Journal ArticleAm J Kidney Dis · December 2011
BACKGROUND: Identification of persons with chronic kidney disease (CKD) who are at highest risk to progress to end-stage renal disease (ESRD) is necessary to reduce the burden of kidney failure. The relative utility of traditional markers of kidney functio ...
Full textLink to itemCite
Journal ArticleAm J Kidney Dis · June 2011
BACKGROUND: Connective tissue growth factor (CTGF) is involved in the development and progression of kidney diseases, including diabetic nephropathy and kidney fibrosis, but also may have a role in mesangial repair after injury. It is unknown whether, in t ...
Full textLink to itemCite
Journal ArticleAm J Nephrol · 2011
BACKGROUND: Early detection of individuals at high risk for chronic kidney disease (CKD) may aid prevention. Urinary levels of trefoil factor 3 (TFF3) are associated with acute kidney injury in animal models, but the association of TFF3 levels with inciden ...
Full textLink to itemCite
Journal ArticleUrology · August 2002
OBJECTIVES: To assess the effectiveness of salvage radiotherapy (RT) for a persistent or rising prostate-specific antigen (PSA) level after radical prostatectomy, and to identify the pretreatment factors that may predict for patients likely to benefit from ...
Full textLink to itemCite