Oana Craciunescu
Professor of Radiation Oncology
Current Research Interests
Current Appointments & Affiliations
- Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2021
Contact Information
- 40 Medicine Circle Duke South, Box 3295, Durham, NC 27710
- Box 3295 Med Ctr, Durham, NC 27710
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oana.craciunescu@duke.edu
(919) 660-2192
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Duke Medical Physics Graduate Program Faculty
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Duke Scholars
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Google Scholar
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Radiation ONcology Physics Faculty/Staff
- Background
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Education, Training, & Certifications
- Faculty, Medical Physics Graduate Program, Duke University 2006
- American Board of Radiology (ABR), Medical Physics, American Board of Radiology 2006 - 2020
- Medical Physics Resident, Radiation Oncology Medical Physics Division, Duke University School of Medicine 2001 - 2003
- Ph.D., Duke University 1998
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Previous Appointments & Affiliations
- Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2020
- Associate Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2011 - 2020
- Assistant Professor in Radiation Oncology, Radiation Oncology, Clinical Science Departments 2006 - 2011
- Assistant Clinical Professor in Radiation Oncology, Radiation Oncology, Clinical Science Departments 2003 - 2006
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Leadership & Clinical Positions at Duke
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Duke University Medical Center Medical Physics Resident 2001-2003
Duke University Medical Center Assistant Professor 2003-2011
Duke University Medical Center Associate Professor 2011-2020
Duke University Medical Center Professor 2020-presentClinical Experience (Leadership):
2003-2010; 2015(temp): Lead physicist TBI/TSI team
2003-present: Lead physicist on rotation basis of one of the linear accelerators
2008-2017, 2020-2021: Lead physicist Brachytherapy team
2009-2014: Lead physicist Sarcoma planning team;
2009-present: Lead physicist Gynecological Malignancies planning team
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- Recognition
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In the News
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SEP 15, 2020 AAPM Newsletter , September/October 2020, Vol 45, No., p. 37-38. 5 -
JAN 3, 2018 Duke Health News and Media -
DEC 11, 2004 Duke Health News and Media
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Awards & Honors
- Distinguished Nominee for the 2021 Gordon G. Hammes Faculty Teaching Award from the Duke School of Medicine.. School of Medicine. 2021
- Director’s Award for Exemplary Service. Medical Physics Graduate Program at Duke University. 2019
- Excellence in Mentorship Award. Medical Physics Graduate Program, Duke University. May 13, 2018
- Director’s Award for Exemplary Service,. Duke University Medical Physics Graduate Program. May 2018
- Excellence in Mentorship Award . Medical Physics Graduate Program at Duke University. 2007
- PhD Department Scholarship. Department of Mechanical Engineering and Materials Science, Duke University. 1994
- Expertise
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Subject Headings
- Acute Disease
- Adipose Tissue
- Adult
- Aged
- Algorithms
- Amines
- Analysis of Variance
- Angiogenesis Inhibitors
- Animals
- Antibodies, Monoclonal, Humanized
- Antineoplastic Agents
- Antineoplastic Combined Chemotherapy Protocols
- Area Under Curve
- Biocompatible Materials
- Biomechanical Phenomena
- Biomedical Engineering
- Biophysical Phenomena
- Biophysics
- Blood Vessels
- Body Temperature
- Body Temperature Regulation
- Brachytherapy
- Brain Neoplasms
- Breast Neoplasms
- Cancer
- Catheterization
- Cells, Cultured
- Chemistry, Pharmaceutical
- Chemoradiotherapy
- Chemotherapy, Adjuvant
- Chemotherapy, Cancer, Regional Perfusion
- Cholesterol
- Chondroitin Sulfates
- Cisplatin
- Combined Modality Therapy
- Computer Simulation
- Contrast Media
- Cyclophosphamide
- Diffusion
- Dog Diseases
- Dogs
- Dose-Response Relationship, Radiation
- Doxorubicin
- Drug Compounding
- Drug Delivery Systems
- Electromagnetic Fields
- Electromagnetic Phenomena
- Energy Metabolism
- Equipment Design
- Equipment Failure Analysis
- Etoposide
- Evaluation Studies as Topic
- Extracellular Space
- Feasibility Studies
- Female
- Fiber Optic Technology
- Fibroblasts
- Forelimb
- Fractals
- Gadolinium DTPA
- Gels
- Glioma
- Graft vs Host Disease
- Head and Neck Neoplasms
- Hematologic Neoplasms
- Hemorheology
- Heterocyclic Compounds
- Hindlimb
- Hot Temperature
- Humans
- Hydrogen-Ion Concentration
- Hyperthermia, Induced
- Image Enhancement
- Image Processing, Computer-Assisted
- Immunohistochemistry
- Kaplan-Meier Estimate
- Kidney
- Kinetics
- Liposomes
- Longitudinal Studies
- Lung
- Lung Neoplasms
- Lymphatic Metastasis
- Magnetic Resonance Imaging
- Male
- Mathematics
- Maximum Tolerated Dose
- Melphalan
- Microcirculation
- Microscopy, Electron, Transmission
- Microscopy, Fluorescence
- Middle Aged
- Models, Biological
- Models, Cardiovascular
- Models, Statistical
- Models, Theoretical
- Molecular Targeted Therapy
- Muscle, Skeletal
- Neoadjuvant Therapy
- Neoplasm Invasiveness
- Neoplasm Recurrence, Local
- Neoplasm Staging
- Neoplasms
- North Carolina
- Observer Variation
- Organometallic Compounds
- Organs at Risk
- Paclitaxel
- Patient Positioning
- Pelvis
- Perfusion
- Phantoms, Imaging
- Photons
- Pilot Projects
- Pneumonia
- Polyethylene Glycols
- Porosity
- Prognosis
- Prospective Studies
- Prosthesis Implantation
- Protons
- Pulsatile Flow
- Quality of Life
- Quinazolines
- ROC Curve
- Radiation Injuries
- Radio Waves
- Radiometry
- Radiosurgery
- Radiotherapy
- Radiotherapy Dosage
- Radiotherapy Planning, Computer-Assisted
- Radiotherapy, Adjuvant
- Randomized Controlled Trials as Topic
- Recurrence
- Reproducibility of Results
- Retrospective Studies
- Risk Factors
- Sarcoma
- Sarcoma, Experimental
- Scleroderma, Systemic
- Sensitivity and Specificity
- Soft Tissue Neoplasms
- Software
- Solubility
- Stem Cell Transplantation
- Survival Analysis
- Temperature
- Thermography
- Thermogravimetry
- Thermometers
- Thoracic Neoplasms
- Thoracic Wall
- Time Factors
- Tomography, Emission-Computed, Single-Photon
- Tomography, X-Ray Computed
- Transplantation Conditioning
- Treatment Outcome
- Tumor Burden
- Urinary Bladder
- Urinary Bladder Neoplasms
- Ventricular Dysfunction, Left
- Ventricular Function, Left
- Vidarabine
- Water
- Whole-Body Irradiation
- Young Adult
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Global Scholarship
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Expertise
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- Research
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Selected Grants
- Cross-disciplinary Training in Medical Physics awarded by National Institutes of Health 2007 - 2013
- Unified Approach to Hyperthermia Modeling and Planning awarded by National Institutes of Health 2000 - 2002
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Shenker, Rachel, Carolyn Eckrich, Rachel D’Anna, Donna Niedzwiecki, Anna Rodrigues, Oana Craciunescu, and Junzo Chino. “Adaptive Positron Emission Tomography Radiation Therapy in Patients With Locally Advanced Vulvar Cancer: A Prospective Study.” Advances in Radiation Oncology 8, no. 4 (July 2023): 101208. https://doi.org/10.1016/j.adro.2023.101208.Full Text
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Meltsner, Sheridan G., Anna Rodrigues, Miguel A. Materin, David G. Kirsch, and Oana Craciunescu. “Transitioning from a COMS-based plaque brachytherapy program to using eye physics plaques and plaque simulator treatment planning system: A single institutional experience.” J Appl Clin Med Phys 24, no. 5 (May 2023): e13902. https://doi.org/10.1002/acm2.13902.Full Text Link to Item
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Meltsner, Sheridan G., David G. Kirsch, Miguel A. Materin, Yongbok Kim, Yang Sheng, and Oana Craciunescu. “Dual-source strength seed loading for eye plaque brachytherapy using eye physics eye plaques: A feasibility study.” J Contemp Brachytherapy 14, no. 6 (December 2022): 590–600. https://doi.org/10.5114/jcb.2022.123979.Full Text Open Access Copy Link to Item
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Kheir, Wajiha J., Sandra S. Stinnett, Sheridan Meltsner, Ekaterina Semenova, Yvonne M. Mowery, Oana Craciunescu, David G. Kirsch, and Miguel A. Materin. “Preliminary Results of Uveal Melanoma Treated With Iodine-125 Plaques: Analysis of Disease Control and Visual Outcomes With 63 Gy to the Target Volume.” Adv Radiat Oncol 7, no. 2 (2022): 100869. https://doi.org/10.1016/j.adro.2021.100869.Full Text Link to Item
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Arsenault, Theodore, Fang Fang Yin, Junzo Chino, Oana Craciunescu, and Jim Zheng Chang. “Evaluation of eddy current distortion and field inhomogeneity distortion corrections in MR diffusion imaging using log-demons DIR method.” Phys Med Biol 66, no. 3 (January 29, 2021): 035021. https://doi.org/10.1088/1361-6560/abcb20.Full Text Link to Item
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Ackerson, Bradley G., Qiuwen Wu, Oana Craciunescu, Taofik Oyekunle, Donna Niedzwiecki, Jennie Gupton, Patrick Laug, et al. “Recumbent Total Skin Electron Beam Therapy.” Adv Radiat Oncol 6, no. 4 (2021): 100698. https://doi.org/10.1016/j.adro.2021.100698.Full Text Link to Item
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Rodrigues, Anna, Kelly Loman, Jeff Nawrocki, Jenny K. Hoang, Zheng Chang, Yvonne M. Mowery, Taofik Oyekunle, Donna Niedzwiecki, David M. Brizel, and Oana Craciunescu. “Establishing ADC-Based Histogram and Texture Features for Early Treatment-Induced Changes in Head and Neck Squamous Cell Carcinoma.” Front Oncol 11 (2021): 708398. https://doi.org/10.3389/fonc.2021.708398.Full Text Link to Item
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Subashi, Ergys, Corbin Jacobs, Rodney Hood, David G. Kirsch, and Oana Craciunescu. “A design process for a 3D printed patient-specific applicator for HDR brachytherapy of the orbit.” 3d Print Med 6, no. 1 (June 29, 2020): 15. https://doi.org/10.1186/s41205-020-00068-3.Full Text Link to Item
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Campelo, Sabrina, Ergys Subashi, Sheridan G. Meltsner, Zheng Chang, Junzo Chino, and Oana Craciunescu. “Multimaterial three-dimensional printing in brachytherapy: Prototyping teaching tools for interstitial and intracavitary procedures in cervical cancers.” Brachytherapy 19, no. 6 (2020): 767–76. https://doi.org/10.1016/j.brachy.2020.07.013.Full Text Link to Item
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Whitley, Melodi Javid, Willis Barrow, Oana I. Craciunescu, Michelle Pavlis, and David G. Kirsch. “Kaposi sarcoma in a patient with postpolio syndrome.” Cutis 104, no. 5 (November 2019): E20–22.Link to Item
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Carpenter, David J., Corbin D. Jacobs, Terence Z. Wong, Oana Craciunescu, and Junzo P. Chino. “Changes on Midchemoradiation Therapy Fluorodeoxyglucose Positron Emission Tomography for Cervical Cancer Are Associated with Prognosis.” Int J Radiat Oncol Biol Phys 105, no. 2 (October 1, 2019): 356–66. https://doi.org/10.1016/j.ijrobp.2019.06.2506.Full Text Link to Item
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Sullivan, Keith M., Ellen A. Goldmuntz, Lynette Keyes-Elstein, Peter A. McSweeney, Ashley Pinckney, Beverly Welch, Maureen D. Mayes, et al. “Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma.” N Engl J Med 378, no. 1 (January 4, 2018): 35–47. https://doi.org/10.1056/nejmoa1703327.Full Text Link to Item
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Belley, Matthew D., Oana Craciunescu, Zheng Chang, Brian W. Langloss, Ian N. Stanton, Terry T. Yoshizumi, Michael J. Therien, and Junzo P. Chino. “Real-time dose-rate monitoring with gynecologic brachytherapy: Results of an initial clinical trial.” Brachytherapy 17, no. 6 (2018): 1023–29. https://doi.org/10.1016/j.brachy.2018.07.014.Full Text Link to Item
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Brownstein, J., J. P. Chino, O. I. Craciunescu, and K. Light. “FDG Positron Emission Tomography as an Indicator of Myelosuppression in Women Undergoing Pelvic Chemoradiation Therapy.” Int J Radiat Oncol Biol Phys 96, no. 2S (October 1, 2016): E293. https://doi.org/10.1016/j.ijrobp.2016.06.1362.Full Text Link to Item
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Natesan, D., O. I. Craciunescu, P. S. Lee, and J. P. Chino. “FDG Positron Emission Tomography (PET)/Computed Tomography Characteristics of Vulvar Cancer: Posttreatment PET Correlates With Clinical Outcomes.” Int J Radiat Oncol Biol Phys 96, no. 2S (October 1, 2016): S52–53. https://doi.org/10.1016/j.ijrobp.2016.06.137.Full Text Link to Item
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Rodrigues, A., J. Nawrocki, K. Light, J. P. Chino, and O. I. Craciunescu. “Evaluation of Dose-Volume Metrics of an 18F-FDG Positron Emission Tomography Adaptive Treatment Planning Protocol for Gynecological Malignancies.” Int J Radiat Oncol Biol Phys 96, no. 2S (October 1, 2016): E296. https://doi.org/10.1016/j.ijrobp.2016.06.1368.Full Text Link to Item
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Susko, M., O. I. Craciunescu, S. G. Meltsner, Y. Yang, B. Steffey, J. Cai, and J. P. Chino. “Vaginal Toxicity From Vaginal Brachytherapy and Capri-Based Systems.” Int J Radiat Oncol Biol Phys 96, no. 2S (October 1, 2016): E287–88. https://doi.org/10.1016/j.ijrobp.2016.06.1348.Full Text Link to Item
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Vergalasova, I., K. Light, J. P. Chino, and O. I. Craciunescu. “Simultaneous Integrated Boost (SIB) for Treatment of Gynecological Malignancies: Intensity Modulated Radiation Therapy (IMRT) Versus Volumetric Modulated Arc Therapy (VMAT).” Int J Radiat Oncol Biol Phys 96, no. 2S (October 1, 2016): E677–78. https://doi.org/10.1016/j.ijrobp.2016.06.2324.Full Text Link to Item
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Belley, M. D., A. Faught, B. Moore, E. Subashi, B. Langloss, M. J. Therien, T. T. Yoshizumi, J. P. Chino, and O. Craciunescu. “WE-DE-201-07: Measurement of Real-Time Dose for Tandem and Ovoid Brachytherapy Procedures Using a High Precision Optical Fiber Radiation Detector.” Med Phys 43, no. 6 (June 2016): 3809–10. https://doi.org/10.1118/1.4957812.Full Text Link to Item
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Chino, J. P., M. D. Belley, Z. Chang, B. Langloss, T. T. Yoshizumi, M. J. Therien, and O. I. Craciunescu. “Real Time Dosimetry for Gynecologic Brachytherapy: Initial Results of a Prospective Clinical Trial (vol 93, pg S203, 2015).” International Journal of Radiation Oncology Biology Physics 95, no. 2 (June 1, 2016): 858–59.Link to Item
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Craciunescu, O. “TU-FG-202-01: Modern Intracavitary GYN Brachytherapy.” Med Phys 43, no. 6 (June 2016): 3759. https://doi.org/10.1118/1.4957562.Full Text Link to Item
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Loman, K., J. Nawrocki, J. Hoang, D. Yoo, Z. Chang, Y. Mowery, X. Li, B. Peterson, D. Brizel, and O. Craciunescu. “SU-F-R-15: Establishing Relevant ADC-Based Texture Analysis Metrics for Quantifying Early Treatment-Induced Changes in Head and Neck Squamous Cell Carcinoma.” Med Phys 43, no. 6 (June 2016): 3376. https://doi.org/10.1118/1.4955787.Full Text Link to Item
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Yang, Y., J. Cai, S. Meltsner, Z. Chang, and O. Craciunescu. “SU-G-201-13: Investigation of Dose Variation Induced by HDR Ir-192 Source Global Shift Within the Varian Ring Applicator Using Monte Carlo Methods.” Medical Physics 43, no. 6 (June 2016): 3625–26. https://doi.org/10.1118/1.4956886.Full Text
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Susko, Matthew, Oana Craciunescu, Sheridan Meltsner, Yun Yang, Beverly Steffey, Jing Cai, and Junzo Chino. “Vaginal Dose Is Associated With Toxicity in Image Guided Tandem Ring or Ovoid-Based Brachytherapy.” Int J Radiat Oncol Biol Phys 94, no. 5 (April 1, 2016): 1099–1105. https://doi.org/10.1016/j.ijrobp.2015.12.360.Full Text Link to Item
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Whitley, Melodi Javid, Adela R. Cardones, Oana I. Craciunescu, and David G. Kirsch. “Externally applied high-dose-rate brachytherapy for deeply invasive cutaneous squamous cell carcinoma in an older patient.” Pract Radiat Oncol 6, no. 4 (2016): e141–44. https://doi.org/10.1016/j.prro.2015.11.008.Full Text Link to Item
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Tandberg, Daniel J., Oana Craciunescu, and Chris R. Kelsey. “Radiation Therapy for Cutaneous T-Cell Lymphomas.” Dermatol Clin 33, no. 4 (October 2015): 703–13. https://doi.org/10.1016/j.det.2015.05.006.Full Text Link to Item
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Nawrocki, J., J. Chino, S. Das, and O. Craciunescu. “SU-E-J-262: Variability in Texture Analysis of Gynecological Tumors in the Context of An 18F-FDG PET Adaptive Protocol.” Med Phys 42, no. 6 (June 2015): 3327. https://doi.org/10.1118/1.4924348.Full Text Link to Item
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Nawrocki, J., J. Chino, S. Das, and O. Craciunescu. “SU-E-J-249: Characterization of Gynecological Tumor Heterogeneity Using Texture Analysis in the Context of An 18F-FDG PET Adaptive Protocol.” Med Phys 42, no. 6 (June 2015): 3323. https://doi.org/10.1118/1.4924335.Full Text Link to Item
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Poplawski, L., T. Li, J. Chino, and O. Craciunescu. “SU-E-J-105: Trusting Dose Deformation and Accumulation for GYN Brachytherapy.” Med Phys 42, no. 6 (June 2015): 3288. https://doi.org/10.1118/1.4924192.Full Text Link to Item
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Siamakpour-Reihani, Sharareh, Kouros Owzar, Chen Jiang, Peter M. Scarbrough, Oana I. Craciunescu, Janet K. Horton, Holly K. Dressman, Kimberly L. Blackwell, and Mark W. Dewhirst. “Genomic profiling in locally advanced and inflammatory breast cancer and its link to DCE-MRI and overall survival.” Int J Hyperthermia 31, no. 4 (June 2015): 386–95. https://doi.org/10.3109/02656736.2015.1016557.Full Text Link to Item
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Boyle, John, Oana Craciunescu, Beverly Steffey, Jing Cai, and Junzo Chino. “Methods, safety, and early clinical outcomes of dose escalation using simultaneous integrated and sequential boosts in patients with locally advanced gynecologic malignancies.” Gynecol Oncol 135, no. 2 (November 2014): 239–43. https://doi.org/10.1016/j.ygyno.2014.08.037.Full Text Link to Item
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Hoang, Jenny K., Kingshuk Roy Choudhury, Jim Chang, Oana I. Craciunescu, David S. Yoo, and David M. Brizel. “Diffusion-weighted imaging for head and neck squamous cell carcinoma: quantifying repeatability to understand early treatment-induced change.” Ajr Am J Roentgenol 203, no. 5 (November 2014): 1104–8. https://doi.org/10.2214/AJR.14.12838.Full Text Link to Item
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Zagar, Timothy M., Zeljko Vujaskovic, Silvia Formenti, Hope Rugo, Franco Muggia, Brigid O’Connor, Robert Myerson, et al. “Two phase I dose-escalation/pharmacokinetics studies of low temperature liposomal doxorubicin (LTLD) and mild local hyperthermia in heavily pretreated patients with local regionally recurrent breast cancer.” Int J Hyperthermia 30, no. 5 (August 2014): 285–94. https://doi.org/10.3109/02656736.2014.936049.Full Text Link to Item
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Vidovic, A. K., T. Juang, S. Meltsner, J. Adamovics, J. Chino, B. Steffey, O. Craciunescu, and M. Oldham. “An investigation of a PRESAGE® in vivo dosimeter for brachytherapy.” Phys Med Biol 59, no. 14 (July 21, 2014): 3893–3905. https://doi.org/10.1088/0031-9155/59/14/3893.Full Text Link to Item
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Onxley, Jennifer D., David S. Yoo, Naira Muradyan, James R. MacFall, David M. Brizel, and Oana I. Craciunescu. “Comprehensive population-averaged arterial input function for dynamic contrast-enhanced vmagnetic resonance imaging of head and neck cancer.” Int J Radiat Oncol Biol Phys 89, no. 3 (July 1, 2014): 658–65. https://doi.org/10.1016/j.ijrobp.2014.03.006.Full Text Link to Item
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Craciunescu, O., D. Todor, and A. de Leeuw. “WE-F-BRD-01: HDR Brachytherapy II: Integrating Imaging with HDR.” Med Phys 41, no. 6 (June 2014): 513–14. https://doi.org/10.1118/1.4889467.Full Text Link to Item
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Lu, S., L. Yuan, O. Craciunescu, Y. Ge, F. Yin, and Q. Wu. “TU-C-17A-11: Progressive Knowledge Modeling for Pelvic IMRT/VMAT Treatment Planning.” Med Phys 41, no. 6 (June 2014): 460. https://doi.org/10.1118/1.4889286.Full Text Link to Item
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Nawrocki, J., J. Chino, K. Light, I. Vergalasova, and O. Craciunescu. “SU-E-J-124: FDG PET Metrics Analysis in the Context of An Adaptive PET Protocol for Node Positive Gynecologic Cancer Patients.” Med Phys 41, no. 6 (June 2014): 184. https://doi.org/10.1118/1.4888176.Full Text Link to Item
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Inman, Brant A., Paul R. Stauffer, Oana A. Craciunescu, Paolo F. Maccarini, Mark W. Dewhirst, and Zeljko Vujaskovic. “A pilot clinical trial of intravesical mitomycin-C and external deep pelvic hyperthermia for non-muscle-invasive bladder cancer.” Int J Hyperthermia 30, no. 3 (May 2014): 171–75. https://doi.org/10.3109/02656736.2014.882021.Full Text Link to Item
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Juang, Titania, Paul R. Stauffer, Oana A. Craciunescu, Paolo F. Maccarini, Yu Yuan, Shiva K. Das, Mark W. Dewhirst, Brant A. Inman, and Zeljko Vujaskovic. “Thermal dosimetry characteristics of deep regional heating of non-muscle invasive bladder cancer.” Int J Hyperthermia 30, no. 3 (May 2014): 176–83. https://doi.org/10.3109/02656736.2014.898338.Full Text Link to Item
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Boyle, John M., Oana Craciunescu, Beverley Steffey, Jing Cai, and Junzo Chino. “Body mass index, dose to organs at risk during vaginal brachytherapy, and the role of three-dimensional CT-based treatment planning.” Brachytherapy 13, no. 4 (2014): 332–36. https://doi.org/10.1016/j.brachy.2013.12.002.Full Text Link to Item
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Craciunescu, O., A. Gaspar, M. Trif, M. Moisei, A. Oancea, L. Moldovan, and O. Zarnescu. “Preparation and characterization of a collagen-liposome-chondroitin sulfate matrix with potential application for inflammatory disorders treatment.” Journal of Nanomaterials 2014 (January 1, 2014). https://doi.org/10.1155/2014/903691.Full Text
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Chukkala, D. P., K. Arunachalam, O. I. Craciunescu, P. Maccarini, P. R. Stauffer, and J. L. Schlorff. “An imaging study to assess displacement between brachytherapy applicator and chestwall during simultaneous thermobrachytherapy of cancer.” 2013 Ieee 2nd International Conference on Image Information Processing, Ieee Iciip 2013, December 1, 2013, 247–50. https://doi.org/10.1109/ICIIP.2013.6707592.Full Text
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Cabrera, Alvin R., Kyle C. Cuneo, Annick Desjardins, John H. Sampson, Frances McSherry, James E. Herndon, Katherine B. Peters, et al. “Concurrent stereotactic radiosurgery and bevacizumab in recurrent malignant gliomas: a prospective trial.” Int J Radiat Oncol Biol Phys 86, no. 5 (August 1, 2013): 873–79. https://doi.org/10.1016/j.ijrobp.2013.04.029.Full Text Link to Item
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Craciunescu, O., J. Cai, and J. Chino. “TH-D-108-01: Implementing MR-Guided Adaptive Brachytherapy for Cervical Cancer.” Med Phys 40, no. 6Part33 (June 2013): 549. https://doi.org/10.1118/1.4815807.Full Text Link to Item
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Vidovic, A., A. Juang, B. Steffey, S. Meltsner, J. Adamovics, J. Chino, O. Craciunescu, and M. Oldham. “SU-D-108-03: Evaluation of the Feasibility of a Novel Radiochromic Dosimetry System for In-Vivo Dose Verification in Organs at Risk in HDR Intracavitary Gynecological Brachytherapy.” Med Phys 40, no. 6Part3 (June 2013): 104. https://doi.org/10.1118/1.4814013.Full Text Link to Item
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Ding, L., J. Chino, J. Cai, B. Steffey, S. Meltsner, Y. Yang, and O. Craciunescu. “SU‐E‐J‐88: Dose Summation Between Multimodality Treatments for Cervical Cancer.” Medical Physics 40, no. 6 (January 1, 2013): 170. https://doi.org/10.1118/1.4814300.Full Text
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Arunachalam, Kavitha, Oana I. Craciunescu, Edward J. Markewitz, Paolo F. Maccarini, Jaime L. Schlorff, and Paul R. Stauffer. “Preclinical assessment of comfort and secure fit of thermobrachytherapy surface applicator (TBSA) on volunteer subjects.” J Appl Clin Med Phys 13, no. 5 (September 6, 2012): 3845. https://doi.org/10.1120/jacmp.v13i5.3845.Full Text Link to Item
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Adamson, Justus, Joseph Newton, Yun Yang, Beverly Steffey, Jing Cai, John Adamovics, Mark Oldham, Junzo Chino, and Oana Craciunescu. “Commissioning a CT-compatible LDR tandem and ovoid applicator using Monte Carlo calculation and 3D dosimetry.” Med Phys 39, no. 7Part1 (July 2012): 4515–23. https://doi.org/10.1118/1.4730501.Full Text Link to Item
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Adamson, J., J. Newton, B. Steffey, J. Cai, J. Adamovics, M. Oldham, J. Chino, and O. Craciunescu. “SU-D-213AB-05: Commissioning a CT Compatible LDR T&O Applicator Using Analytical Calculation with ID and 3D Dosimetry.” Med Phys 39, no. 6Part3 (June 2012): 3612. https://doi.org/10.1118/1.4734665.Full Text Link to Item
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Craciunescu, O., J. Cai, A. de Leeuw, and C. Kirisits. “TU-E-213CD-01: Image Guided Adaptive Brachytherapy for Cervical Cancer.” Med Phys 39, no. 6Part24 (June 2012): 3913. https://doi.org/10.1118/1.4735972.Full Text Link to Item
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Onxley, J., D. Yoo, N. Muradyan, J. MacFall, D. Brizel, and O. Craciunescu. “SU-D-BRB-06: Comprehensive Population-Averaged Arterial Input Function (AIF) for DCE-MRI of Head and Neck Cancer.” Med Phys 39, no. 6Part3 (June 2012): 3615–16. https://doi.org/10.1118/1.4734678.Full Text Link to Item
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Yuan, Yu, Cory Wyatt, Paolo Maccarini, Paul Stauffer, Oana Craciunescu, James Macfall, Mark Dewhirst, and Shiva K. Das. “A heterogeneous human tissue mimicking phantom for RF heating and MRI thermal monitoring verification.” Phys Med Biol 57, no. 7 (April 7, 2012): 2021–37. https://doi.org/10.1088/0031-9155/57/7/2021.Full Text Link to Item
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Craciunescu, Oana I., David S. Yoo, Esi Cleland, Naira Muradyan, Madeline D. Carroll, James R. MacFall, Daniel P. Barboriak, and David M. Brizel. “Dynamic contrast-enhanced MRI in head-and-neck cancer: the impact of region of interest selection on the intra- and interpatient variability of pharmacokinetic parameters.” Int J Radiat Oncol Biol Phys 82, no. 3 (March 1, 2012): e345–50. https://doi.org/10.1016/j.ijrobp.2011.05.059.Full Text Link to Item
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Yoo, David S., John P. Kirkpatrick, Oana Craciunescu, Gloria Broadwater, Bercedis L. Peterson, Madeline D. Carroll, Robert Clough, et al. “Prospective trial of synchronous bevacizumab, erlotinib, and concurrent chemoradiation in locally advanced head and neck cancer.” Clin Cancer Res 18, no. 5 (March 1, 2012): 1404–14. https://doi.org/10.1158/1078-0432.CCR-11-1982.Full Text Link to Item
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Yuan, Yu, Kung-Shan Cheng, Oana I. Craciunescu, Paul R. Stauffer, Paolo F. Maccarini, Kavitha Arunachalam, Zeljko Vujaskovic, Mark W. Dewhirst, and Shiva K. Das. “Utility of treatment planning for thermochemotherapy treatment of nonmuscle invasive bladder carcinoma.” Med Phys 39, no. 3 (March 2012): 1170–81. https://doi.org/10.1118/1.3679839.Full Text Link to Item
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McMahon, Ryan, Tingliang Zhuang, Beverly A. Steffey, Haijun Song, and Oana I. Craciunescu. “Commissioning of Varian ring & tandem HDR applicators: reproducibility and interobserver variability of dwell position offsets.” J Appl Clin Med Phys 12, no. 4 (November 15, 2011): 3447. https://doi.org/10.1120/jacmp.v12i4.3447.Full Text Link to Item
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Kelsey, Chris R., Mitchell E. Horwitz, Junzo P. Chino, Oana Craciunescu, Beverly Steffey, Rodney J. Folz, Nelson J. Chao, David A. Rizzieri, and Lawrence B. Marks. “Severe pulmonary toxicity after myeloablative conditioning using total body irradiation: an assessment of risk factors.” Int J Radiat Oncol Biol Phys 81, no. 3 (November 1, 2011): 812–18. https://doi.org/10.1016/j.ijrobp.2010.06.058.Full Text Link to Item
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Cabrera, A. R., O. Craciunescu, K. C. Cuneo, Z. Chang, and J. P. Kirkpatrick. “Evaluating Recurrent Gliomas with Diffusion-weighted MR Imaging Before and After Concurrent Radiosurgery and Bevacizumab.” International Journal of Radiation Oncology*Biology*Physics 81, no. 2 (October 2011): S793–S793. https://doi.org/10.1016/j.ijrobp.2011.06.1387.Full Text
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Das, S. K., D. S. Yoo, O. Craciunescu, J. Hoang, and D. M. Brizel. “The Use of Serial FDG-PET Scanning to Develop Metabolic Response Criteria to Chemoradiation in Head and Neck Cancer (HNC).” International Journal of Radiation Oncology*Biology*Physics 81, no. 2 (October 2011): S531–S531. https://doi.org/10.1016/j.ijrobp.2011.06.823.Full Text
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Craciunescu, Oana I., Beverly A. Steffey, Chris R. Kelsey, Nicole A. Larrier, Cathy J. Paarz-Largay, Robert G. Prosnitz, Nelson Chao, et al. “Renal shielding and dosimetry for patients with severe systemic sclerosis receiving immunoablation with total body irradiation in the scleroderma: cyclophosphamide or transplantation trial.” Int J Radiat Oncol Biol Phys 79, no. 4 (March 15, 2011): 1248–55. https://doi.org/10.1016/j.ijrobp.2010.05.036.Full Text Link to Item
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Li, Zhen, Martin Vogel, Paolo F. Maccarini, Vadim Stakhursky, Brian J. Soher, Oana I. Craciunescu, Shiva Das, Omar A. Arabe, Williams T. Joines, and Paul R. Stauffer. “Improved hyperthermia treatment control using SAR/temperature simulation and PRFS magnetic resonance thermal imaging.” Int J Hyperthermia 27, no. 1 (2011): 86–99. https://doi.org/10.3109/02656736.2010.501509.Full Text Link to Item
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McMahon, R., T. Zhuang, B. A. Steffey, H. Song, and O. I. Craciunescu. “Commissioning of Varian ring & tandem HDR applicators: Reproducibility and interobserver variability of dwell position offsets.” Journal of Applied Clinical Medical Physics 12, no. 4 (January 1, 2011): 50–62. https://doi.org/10.1120/jacmp.v12i4.3447.Full Text
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Pierquet, M., O. Craciunescu, B. Steffey, H. Song, and M. Oldham. “On the Feasibility of Verification of 3D Dosimetry Near Brachytherapy Sources Using PRESAGE/Optical-CT.” J Phys Conf Ser 250, no. 1 (December 7, 2010): 120911–15. https://doi.org/10.1088/1742-6596/250/1/012091.Full Text Link to Item
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Popescu, Maria-Cristina, Cornelia Vasile, and Oana Craciunescu. “Structural analysis of some soluble elastins by means of FT-IR and 2D IR correlation spectroscopy.” Biopolymers 93, no. 12 (December 2010): 1072–84. https://doi.org/10.1002/bip.21524.Full Text Link to Item
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Craciunescu, Oana, David Brizel, Esi Cleland, David Yoo, Naira Muradyan, Madeline Carroll, Daniel Barboriak, and James MacFall. “Dynamic contrast enhanced-MRI in head and neck cancer patients: Variability of the precontrast longitudinal relaxation time (T10).” Med Phys 37, no. 6Part1 (June 2010): 2683–92. https://doi.org/10.1118/1.3427487.Full Text Link to Item
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Arunachalam, K., P. F. Maccarini, O. I. Craciunescu, J. L. Schlorff, and P. R. Stauffer. “Thermal characteristics of thermobrachytherapy surface applicators for treating chest wall recurrence.” Phys Med Biol 55, no. 7 (April 7, 2010): 1949–69. https://doi.org/10.1088/0031-9155/55/7/011.Full Text Link to Item
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Craciunescu, Oana I., Donald E. Thrall, Zeljko Vujaskovic, and Mark W. Dewhirst. “Magnetic resonance imaging: a potential tool in assessing the addition of hyperthermia to neoadjuvant therapy in patients with locally advanced breast cancer.” Int J Hyperthermia 26, no. 7 (2010): 625–37. https://doi.org/10.3109/02656736.2010.499526.Full Text Link to Item
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Stauffer, Paul R., Paolo Maccarini, Kavitha Arunachalam, Oana Craciunescu, Chris Diederich, Titania Juang, Francesca Rossetto, et al. “Conformal microwave array (CMA) applicators for hyperthermia of diffuse chest wall recurrence.” Int J Hyperthermia 26, no. 7 (2010): 686–98. https://doi.org/10.3109/02656736.2010.501511.Full Text Link to Item
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Vujaskovic, Zeljko, Dong W. Kim, Ellen Jones, Lan Lan, Linda McCall, Mark W. Dewhirst, Oana Craciunescu, et al. “A phase I/II study of neoadjuvant liposomal doxorubicin, paclitaxel, and hyperthermia in locally advanced breast cancer.” Int J Hyperthermia 26, no. 5 (2010): 514–21. https://doi.org/10.3109/02656731003639364.Full Text Link to Item
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Zagar, Timothy M., James R. Oleson, Zeljko Vujaskovic, Mark W. Dewhirst, Oana I. Craciunescu, Kimberly L. Blackwell, Leonard R. Prosnitz, and Ellen L. Jones. “Hyperthermia for locally advanced breast cancer.” Int J Hyperthermia 26, no. 7 (2010): 618–24. https://doi.org/10.3109/02656736.2010.501051.Full Text Link to Item
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Zagar, Timothy M., James R. Oleson, Zeljko Vujaskovic, Mark W. Dewhirst, Oana I. Craciunescu, Kimberly L. Blackwell, Leonard R. Prosnitz, and Ellen L. Jones. “Hyperthermia combined with radiation therapy for superficial breast cancer and chest wall recurrence: a review of the randomised data.” Int J Hyperthermia 26, no. 7 (2010): 612–17. https://doi.org/10.3109/02656736.2010.487194.Full Text Link to Item
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Moldovan, L., O. Craciunescu, E. I. Oprita, M. Balan, and O. Zarnescu. “Collagen-chondroitin sulfate-hydroxyapatite porous composites: preparation, characterization and in vitro biocompatibility testing.” Romanian Biotechnological Letters 14, no. 3 (November 17, 2009): 4459–66.
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Craciunescu, Oana I., Paul R. Stauffer, Brian J. Soher, Cory R. Wyatt, Omar Arabe, Paolo Maccarini, Shiva K. Das, et al. “Accuracy of real time noninvasive temperature measurements using magnetic resonance thermal imaging in patients treated for high grade extremity soft tissue sarcomas.” Med Phys 36, no. 11 (November 2009): 4848–58. https://doi.org/10.1118/1.3227506.Full Text Link to Item
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Viglianti, Benjamin L., Michael Lora-Michiels, Jeanie M. Poulson, Lan Lan, Daohai Yu, Linda Sanders, Oana Craciunescu, et al. “Dynamic contrast-enhanced magnetic resonance imaging as a predictor of clinical outcome in canine spontaneous soft tissue sarcomas treated with thermoradiotherapy.” Clin Cancer Res 15, no. 15 (August 1, 2009): 4993–5001. https://doi.org/10.1158/1078-0432.CCR-08-2222.Full Text Link to Item
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Stakhursky, Vadim L., Omar Arabe, Kung-Shan Cheng, James Macfall, Paolo Maccarini, Oana Craciunescu, Mark Dewhirst, Paul Stauffer, and Shiva K. Das. “Real-time MRI-guided hyperthermia treatment using a fast adaptive algorithm.” Phys Med Biol 54, no. 7 (April 7, 2009): 2131–45. https://doi.org/10.1088/0031-9155/54/7/019.Full Text Link to Item
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Craciunescu, O., C. Tardei, and L. Moldovana. “Nano-β-tricalcium phosphate/collagen materials with improved biostability for bone replacement applications.” Proceedings of Spie the International Society for Optical Engineering 7297 (March 23, 2009). https://doi.org/10.1117/12.823658.Full Text
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Stauffer, Pr, Oi Craciunescu, P. Maccarini, C. Wyatt, K. Arunachalam, O. Arabe, V. Stakhursky, et al. “Clinical Utility of Magnetic Resonance Thermal Imaging (MRTI) For Realtime Guidance of Deep Hyperthermia.” Proc Spie Int Soc Opt Eng 7181 (February 25, 2009). https://doi.org/10.1117/12.812188.Full Text Link to Item
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Arunachalam, Kavitha, Oana I. Craciunescu, Paolo F. Maccarini, Jaime L. Schlorff, Edward Markowitz, and Paul R. Stauffer. “Progress on ThermoBrachytherapy Surface Applicator for Superficial Tissue Diseases.” Proc Spie Int Soc Opt Eng 7181 (February 12, 2009). https://doi.org/10.1117/12.809493.Full Text Link to Item
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Bratu, M. M., F. Roncea, L. Moldovan, O. Craciunescu, T. Negreanu-Pîrjol, and G. Tarǎlungǎ. “In vitro evaluation of new topical preparation based on polyphenols, zinc and a matrix animal components.” Archives of the Balkan Medical Union 44, no. 1 (January 1, 2009): 31–34.
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Craciunescu, Oana I., Kimberly L. Blackwell, Ellen L. Jones, James R. Macfall, Daohai Yu, Zeljko Vujaskovic, Terence Z. Wong, et al. “DCE-MRI parameters have potential to predict response of locally advanced breast cancer patients to neoadjuvant chemotherapy and hyperthermia: a pilot study.” Int J Hyperthermia 25, no. 6 (2009): 405–15. https://doi.org/10.1080/02656730903022700.Full Text Link to Item
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Maccarini, Paolo F., Kavitha Arunachalam, Titania Juang, Valeria De Luca, Sneha Rangarao, Daniel Neumann, Carlos Daniel Martins, Oana Craciunescu, and Paul R. Stauffer. “Shaping and resizing of multifed slot radiators used in conformal microwave antenna arrays for hyperthermia treatment of large superficial diseases.” Int Conf Electromagn Adv Appl, 2009. https://doi.org/10.1109/ICEAA.2009.5297299.Full Text Link to Item
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Tardei, C., F. Grigore, L. Moldovan, O. Craciunescu, and E. I. Oprita. “Preparation and characterization of bioresorbable synthetic scaffolds composed from different beta-tricalcium phosphate powders and collagen.” A Global Road Map for Ceramic Materials and Technologies: Forecasting the Future of Ceramics, International Ceramic Federation 2nd International Congress on Ceramics, Icc 2008, Final Programme, December 1, 2008.
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Trif, Mihaela, Lucia Moldovan, Magdalena Moisei, Oana Craciunescu, and Otilia Zarnescu. “Liposomes-entrapped chondroitin sulphate: ultrastructural characterization and in vitro biocompatibility.” Micron 39, no. 7 (October 2008): 1042–45. https://doi.org/10.1016/j.micron.2008.01.008.Full Text Link to Item
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Cheng, Kung-Shan, Vadim Stakhursky, Oana I. Craciunescu, Paul Stauffer, Mark Dewhirst, and Shiva K. Das. “Fast temperature optimization of multi-source hyperthermia applicators with reduced-order modeling of 'virtual sources'.” Phys Med Biol 53, no. 6 (March 21, 2008): 1619–35. https://doi.org/10.1088/0031-9155/53/6/008.Full Text Link to Item
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Oprita, E. I., L. Moldovan, O. Craciunescu, and O. Zarnescu. “In vitro behaviour of osteoblast cells seeded into a COL/β-TCP composite scaffold.” Central European Journal of Biology 3, no. 1 (March 1, 2008): 31–37. https://doi.org/10.2478/s11535-007-0047-5.Full Text
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Craciunescu, O., M. Lungu, O. Zarnescu, A. Gaspar, and L. Moldovan. “Polyurethane-based materials covered with natural polymers for medical applications.” Materiale Plastice 45, no. 2 (January 1, 2008): 163–66.
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Moldovan, L., O. Craciunescu, M. Balan, A. Gaspar, and E. Gherghina. “The purification, physico-chemical characterization and bioactivity of polysaccharides from Viscum album.” Revista De Chimie 59, no. 9 (January 1, 2008): 1022–25. https://doi.org/10.37358/rc.08.9.1961.Full Text
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Moldovan, L., O. Craciunescu, O. Zarnescu, D. Macocinschi, and D. Bojin. “Preparation and characterization of new biocompatibilizecd polymeric materials for medical use.” Journal of Optoelectronics and Advanced Materials 10, no. 4 (January 1, 2008): 942–47.
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Moldovan, L., O. Craciunescu, M. Balan, E. I. Oprita, and O. Zarnescu. “Synthesis and biocompatibility of porous collagen/chondroitin sulfate/hydroxyapatite composites for bone tissue engineering.” European Cells and Materials 14, no. SUPPL.1 (August 1, 2007): 80.
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Craciunescu, O., L. M. Stefan, M. Balan, and L. Moldovan. “Evaluation of the radioprotective activity of new green tea-collagen materials.” Journal of Optoelectronics and Advanced Materials 9, no. 8 (January 1, 2007): 2602–7.
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Thrall, D. E., M. W. Dewhirst, E. L. Jones, Z. Vujaskovic, D. Yu, and O. I. Craciunescu. “A clinically proven, prospective, thermal dose descriptor exists [4].” Clinical Cancer Research 12, no. 6 (March 15, 2006): 1944–46. https://doi.org/10.1158/1078-0432.CCR-05-2446.Full Text
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Oprita, E. I., L. Moldovan, O. Craciunescu, W. Buzgariu, C. Tardei, and O. Zarnescu. “A bioactive collagen-β tricalcium phosphate scaffold for tissue engineering.” Central European Journal of Biology 1, no. 1 (March 1, 2006): 61–72. https://doi.org/10.2478/s11535-006-0005-7.Full Text
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Das, Shiva K., James Macfall, Robert McCauley, Oana Craciunescu, Mark W. Dewhirst, and Thaddeus V. Samulski. “Improved magnetic resonance thermal imaging by combining proton resonance frequency shift (PRFS) and apparent diffusion coefficient (ADC) data.” Int J Hyperthermia 21, no. 7 (November 2005): 657–67. https://doi.org/10.1080/02656730500186346.Full Text Link to Item
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Craciunescu, O. I., E. L. Jones, K. L. Blackwell, T. Z. Wong, E. L. Rosen, Z. Vujaskovic, J. R. MacFall, et al. “Characterizing tumor changes during neoadjuvant treatment of locally advanced breast cancer patients (LABC) using dynamic-enhanced magnetic resonance imaging (DE-MRI).” Proc. Spie Int. Soc. Opt. Eng. (Usa) 5698, no. 1 (2005): 116–25. https://doi.org/10.1117/12.591173.Full Text Link to Item
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Das, Shiva K., Alan H. Baydush, Sumin Zhou, Moyed Miften, Xiaoli Yu, Oana Craciunescu, Mark Oldham, et al. “Predicting radiotherapy-induced cardiac perfusion defects.” Med Phys 32, no. 1 (January 2005): 19–27. https://doi.org/10.1118/1.1823571.Full Text Link to Item
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Das, S. K., M. M. Miften, S. Zhou, M. Bell, M. T. Munley, C. S. Whiddon, O. Craciunescu, et al. “Feasibility of optimizing the dose distribution in lung tumors using fluorine-18-fluorodeoxyglucose positron emission tomography and single photon emission computed tomography guided dose prescriptions.” Med Phys 31, no. 6 (June 2004): 1452–61. https://doi.org/10.1118/1.1750991.Full Text Link to Item
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Craciunescu, O. I., S. K. Das, T. Z. Wong, and T. V. Samulski. “Fractal reconstruction of breast perfusion before and after hyperthermia treatments.” Asme International Mechanical Engineering Congress and Exposition, Proceedings, January 1, 2002, 207–11. https://doi.org/10.1115/IMECE2002-33692.Full Text
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Craciunescu, O. I., S. K. Das, T. Z. Wong, and T. V. Samulski. “Fractal reconstruction of breast perfusion before and after hyperthermia treatments.” American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed 54 (2002): 207–11.
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Craciunescu, O. I., B. W. Raaymakers, A. N. Kotte, S. K. Das, T. V. Samulski, and J. J. Lagendijk. “Discretizing large traceable vessels and using DE-MRI perfusion maps yields numerical temperature contours that match the MR noninvasive measurements.” Med Phys 28, no. 11 (November 2001): 2289–96. https://doi.org/10.1118/1.1408619.Full Text Link to Item
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Craciunescu, O. I., and S. T. Clegg. “Pulsatile blood flow effects on temperature distribution and heat transfer in rigid vessels.” J Biomech Eng 123, no. 5 (October 2001): 500–505. https://doi.org/10.1115/1.1392318.Full Text Link to Item
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Craciunescu, O. I., S. K. Das, J. M. Poulson, and T. V. Samulski. “Three-dimensional tumor perfusion reconstruction using fractal interpolation functions.” Ieee Trans Biomed Eng 48, no. 4 (April 2001): 462–73. https://doi.org/10.1109/10.915713.Full Text Link to Item
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Craciunescu, O. I., B. W. Raaymakers, A. N. T. J. Kotte, S. K. Das, T. V. Samulski, and J. J. W. Lagendijk. “A case study of hyperthermia induced temperature computations in human sarcomas using discrete vasculature and relative perfusion maps.” American Society of Mechanical Engineers, Heat Transfer Division, (Publication) Htd 370 (January 1, 2001): 29–35.
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Craciunescu, O. I., S. K. Das, R. L. McCauley, J. R. MacFall, and T. V. Samulski. “3D numerical reconstruction of the hyperthermia induced temperature distribution in human sarcomas using DE-MRI measured tissue perfusion: validation against non-invasive MR temperature measurements.” Int J Hyperthermia 17, no. 3 (2001): 221–39. https://doi.org/10.1080/02656730110041149.Full Text Link to Item
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Craciunescu, O. I., S. K. Das, and T. V. Samulski. “Piecewise fractal interpolation models to reconstruct the three-dimensional tumor perfusion.” Annual International Conference of the Ieee Engineering in Medicine and Biology Proceedings 1 (December 1, 2000): 292–305.
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Craciunescu, O. I., T. V. Samulski, J. R. MacFall, and S. T. Clegg. “Perturbations in hyperthermia temperature distributions associated with counter-current flow: numerical simulations and empirical verification.” Ieee Trans Biomed Eng 47, no. 4 (April 2000): 435–43. https://doi.org/10.1109/10.828143.Full Text Link to Item
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Craciunescu, O., S. K. Das, and M. W. Dewhirst. “Three-dimensional microvascular networks fractal structure: potential for tissue characterization?” American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed 44 (December 1, 1999): 9–13.
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Craciunescu, O. I., S. K. Das, and S. T. Clegg. “Dynamic contrast-enhanced MRI and fractal characteristics of percolation clusters in two-dimensional tumor blood perfusion.” J Biomech Eng 121, no. 5 (October 1999): 480–86. https://doi.org/10.1115/1.2835076.Full Text Link to Item
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Craciunescu, O. I., L. E. Howle, and S. T. Clegg. “Experimental evaluation of the thermal properties of two tissue equivalent phantom materials.” Int J Hyperthermia 15, no. 6 (1999): 509–18. https://doi.org/10.1080/026567399285503.Full Text Link to Item
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Craciunescu, O., and S. T. Clegg. “Towards the understanding of blood perfusion in tumor vascular networks using contrast-enhanced MRI and invasion percolation.” American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed 40 (December 1, 1998): 143–47.
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Craciunescu, O., and S. T. Clegg. “Perturbations of large vessels on induced temperature distributions. Part A: Three-dimensional simulation study.” American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed 37 (December 1, 1997): 193–98.
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Craciunescu, O., A. Bejan, D. G. Cacuci, and W. Schutz. “Time-dependent interaction between water at supercritical pressures and a hot surface.” Numerical Heat Transfer; Part A: Applications 30, no. 6 (January 1, 1996): 535–53. https://doi.org/10.1080/10407789608913856.Full Text
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Book Sections
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Dewhirst, M., P. R. Stauffer, S. Das, O. I. Craciunescu, and Z. Vujaskovic. “Hyperthermia.” In Clinical Radiation Oncology, 381-398.e6, 2015. https://doi.org/10.1016/B978-0-323-24098-7.00021-6.Full Text
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Dewhirst, M., S. Das, P. Stauffer, O. Craciunescu, Z. Vujaskovic, and D. Thrall. “Hyperthermia.” In Clinical Radiation Oncology: Third Edition, 385–403, 2012. https://doi.org/10.1016/B978-1-4377-1637-5.00021-3.Full Text
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Conference Papers
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Eckroate, B., J. Raffi, R. Venkataraman, Y. Kim, D. Ayala-peacock, and O. Craciunescu. “Development of An Original Multi-Modality Gynecologic Brachytherapy Phantom.” In Medical Physics, 49:E815–E815, 2022.Link to Item
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Shenker, R. F., A. Rodrigues, C. Eckrich, R. D’Anna, D. Niedzwiecki, O. I. Craciunescu, and J. P. Chino. “Adaptive PET Radiation Therapy in Patients with Locally Advanced Vulvar Cancer: A Prospective Study.” In International Journal of Radiation Oncology Biology Physics, 114:E279–E279, 2022.Link to Item
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Radcliffe, B., S. Meltsner, Z. Chang, J. Chino, M. Huang, and O. Craciunescu. “A Retrospective Dose Analysis of High-Dose Rate (HDR) Tandem and Ovoid and Interstitial Needle Cervical Brachytherapy Cases with a Model-Based Dose Calculation Algorithm (MBDCA).” In Medical Physics, Vol. 48, 2021.Link to Item
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Shen, B., Z. Chang, C. Wang, S. Meltsner, J. Chino, and O. Craciunescu. “Uncertainties in MR-To-MR Image Registration for HDR Cervical Brachytherapy.” In Medical Physics, Vol. 48, 2021.Link to Item
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Campelo, S., E. Subashi, Z. Chang, S. G. Meltsner, J. P. Chino, and O. I. Craciunescu. “Multi-material 3D Printing in Brachytherapy– Prototyping Teaching Tools.” In International Journal of Radiation Oncology*Biology*Physics, 108:e437–e437. Elsevier BV, 2020. https://doi.org/10.1016/j.ijrobp.2020.07.2525.Full Text
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Ackerson, B., Q. Wu, O. I. Craciunescu, D. Niedzwiecki, T. Oyekunle, and C. R. Kelsey. “Treatment of Mycosis Fungoides using a Recumbent Total Skin Electron Beam Technique: A Comparison of Dosimetric and Clinical Outcomes.” In International Journal of Radiation Oncology Biology Physics, 108:S167–S167, 2020.Link to Item
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Arsenault, T., F. Yin, J. Chino, O. Craciunescu, and Z. Chang. “EPI Distortion Correction Using Log-Demons Method in MR Diffusion Tensor Images.” In Medical Physics, 47:E531–E531, 2020.Link to Item
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Campelo, S., E. Subashi, Z. Chang, S. Meltsner, J. Chino, and O. Craciunescu. “The Development of a Multi-Material 3D Printed Brachytherapy Training Phantom for Enhanced Resident Training.” In Medical Physics, 47:E858–E858, 2020.Link to Item
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Chibirev, I., S. Meltsner, Z. Chang, M. Materin, D. Kirsch, and O. Craciunescu. “Eye Plaque Brachytherapy Treatment Planning with Fundus Image-Based Tumor Modeling: Retrospective Institutional Experience.” In Medical Physics, 47:E780–E780, 2020.Link to Item
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Rodrigues, A., O. Craciunescu, Q. Wu, and N. Larrier. “Standard of Care Total Body Irradiation for Scleroderma: Duke Institutional Implementation.” In Medical Physics, 47:E490–E490, 2020.Link to Item
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Eclov, N., O. Craciunescu, J. Chino, and Z. Chang. “Evaluation of an MRI-Positive HDR Lumen Marker for HDR Brachytherapy Treatment Planning.” In Medical Physics, 46:E309–E309. WILEY, 2019.Link to Item
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Shen, X., A. Rodrigues, J. Chino, O. Craciunescu, and S. Stephens. “Investigation of Contour-Based Deformable Image Registration cbDIR of Pre-Brachytherapy MRI pbMRI for Target Definition in HDR Cervical Cancer Treatments.” In Medical Physics, 46:E96–E96. WILEY, 2019.Link to Item
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Shen, X., O. Craciunescu, M. Rokni, P. Maccarini, B. Langloss, M. Therien, T. Yoshizumi, and J. Chino. “Simulation-Based Ability of a Real-Time Fiber-Optic Detector to Catch Gross Errors in T& O HDR Brachytherapy Treatments.” In Medical Physics, 46:E197–E197. WILEY, 2019.Link to Item
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Wu, Q., O. I. Craciunescu, A. Rodrigues, S. G. Meltsner, C. Wang, H. Gao, and C. R. Kelsey. “Commissioning and Clinical Implementation of a Laying Down Technique for Total Skin Irradiation.” In International Journal of Radiation Oncology*Biology*Physics, 102:e480–e480. Elsevier BV, 2018. https://doi.org/10.1016/j.ijrobp.2018.07.1371.Full Text
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Craciunescu, O., J. Cai, C. Glide-Hurst, and Y. Yang. “Technical and Professional Preparations for Medical Physicists in the Upcoming MRgRT Era.” In Medical Physics, 45:E696–E696. WILEY, 2018.Link to Item
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Rokni, M., P. Maccarini, X. Shen, B. Moore, B. Langloss, A. Rodrigues, M. Belley, et al. “It is About (real) Time to Verify HDR Treatments: Duke Solution Using Nano-Fiber Optic Detector.” In Medical Physics, 45:E574–E574. WILEY, 2018.Link to Item
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Wu, Q., O. Craciunescu, A. Rodrigues, S. Meltsner, C. Wang, H. Gao, and C. Kelsey. “Commissioning of a Laying Down Technique for Total Skin Irradiation (TSI).” In Medical Physics, 45:E623–E623. WILEY, 2018.Link to Item
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Chino, J. P., J. A. Dorth, G. Suneja, A. Rodrigues, K. Light, and O. I. Craciunescu. “IDEAL-GYN (Integrated Dose Escalation for Advanced Localized Gynecologic Cancers): A Dose Escalation Trial of Bowel Sparing Simultaneous Integrated Boosts for Node Positive Cervical and Vulvar Cancers.” In International Journal of Radiation Oncology*Biology*Physics, 99:E286–E286. Elsevier BV, 2017. https://doi.org/10.1016/j.ijrobp.2017.06.1285.Full Text
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Daley, L. A., O. I. Craciunescu, G. Suneja, K. Light, A. Rodrigues, and J. P. Chino. “Simultaneous Integrated Parametrial/Sidewall Boosts for Cervical Cancer: Late Toxicity and Outcomes.” In International Journal of Radiation Oncology*Biology*Physics, 99:E288–E288. Elsevier BV, 2017. https://doi.org/10.1016/j.ijrobp.2017.06.1290.Full Text
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Langloss, Brian, Ian Stanton, Matthew Belley, John Dooley, Sha Chang, Oana Craciunescu, Junzo Chino, Terry Yoshizumi, and Michael Therien. “Radiation detection and dosimetry using Y2O3:Eu/Li nanoscintillators.” In Abstracts of Papers of the American Chemical Society, Vol. 254. AMER CHEMICAL SOC, 2017.Link to Item
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Damato, Antonio, O. Craciunescu, I. Buzurovic, and G. Cohen. “HDR Brachytherapy: Treatment Verification Methods.” In Medical Physics, 44:3070–3070. WILEY, 2017.Link to Item
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Rodrigues, A., S. Yoon, N. Morales-Medina, M. Oldham, J. Adamovics, S. Meltsner, and O. Craciunescu. “3D Printing and 3D Dosimetry for LDR I-125 Eye Plaque Brachytherapy Quality Assurance.” In Medical Physics, Vol. 44. WILEY, 2017.Link to Item
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Rokni, M., A. Rodrigues, B. Moore, T. Yoshizumi, and O. Craciunescu. “Feasibility of Real-Time Dosimetry for HDR Prostate Brachytherapy Using a Nano-Fiber Optic Detector.” In Medical Physics, 44:3153–3153. WILEY, 2017.Link to Item
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Wang, C., F. Yin, O. Craciunescu, A. Faught, and Z. Chang. “Commissioning of a 3.0T MR Simulator Dedicated for Radiation Oncology Application.” In Medical Physics, Vol. 44. WILEY, 2017.Link to Item
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Natesan, D., O. I. Craciunescu, P. S. Lee, and J. P. Chino. “FDG Positron Emission Tomography (PET)/Computed Tomography Characteristics of Vulvar Cancer: Posttreatment PET Correlates With Clinical Outcomes.” In International Journal of Radiation Oncology Biology Physics, 96:S52–53, 2016.Link to Item
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Vergalasova, I., K. Light, J. P. Chino, and O. I. Craciunescu. “Simultaneous Integrated Boost (SIB) for Treatment of Gynecological Malignancies: Intensity Modulated Radiation Therapy (IMRT) Versus Volumetric Modulated Arc Therapy (VMAT).” In International Journal of Radiation Oncology Biology Physics, 96:E677–78, 2016.Link to Item
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Nawrocki, J., J. P. Chino, and O. I. Craciunescu. “Isolating Texture Features of Gynecological Tumors With High Variability in the Context of an 18F-FDG PET Adaptive Protocol.” In International Journal of Radiation Oncology*Biology*Physics, 93:E614–15. Elsevier BV, 2015. https://doi.org/10.1016/j.ijrobp.2015.07.2116.Full Text
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Boyle, J. M., J. A. Dorth, O. I. Craciunescu, K. Light, J. R. Roper, and J. P. Chino. “Simultaneous Integrated Boost to Pelvic and Para-Aortic Nodes From Cervical Cancer Improves the Dosimetric Therapeutic Ratio.” In International Journal of Radiation Oncology*Biology*Physics, 90:S482–83. Elsevier BV, 2014. https://doi.org/10.1016/j.ijrobp.2014.05.1494.Full Text
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Chino, J. P., J. Nawrocki, I. Vergalasova, K. Light, and O. Craciunescu. “A Prospective Evaluation of FDG PET Adapted IMRT for Node-Positive Gynecologic Cancers.” In International Journal of Radiation Oncology*Biology*Physics, 90:S184–S184. Elsevier BV, 2014. https://doi.org/10.1016/j.ijrobp.2014.05.708.Full Text
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Nawrocki, J., J. Chino, K. Light, I. Vergalasova, and O. Craciunescu. “FDG PET Metrics Analysis in the Context of An Adaptive PET Protocol for Node Positive Gynecologic Cancer Patients.” In Medical Physics, 41:184–184. WILEY, 2014.Link to Item
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Boyle, J. M., J. Dorth, O. Craciunescu, B. Steffey, K. Light, and J. Chino. “Initial Safety and Feasibility of Dose Escalation Using a Simultaneous Integrated Boost in Patients With Locally Advanced Gynecologic Malignancies.” In International Journal of Radiation Oncology*Biology*Physics, 87:S425–26. Elsevier BV, 2013. https://doi.org/10.1016/j.ijrobp.2013.06.1121.Full Text
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Chino, J. P., S. Meltsner, Y. Yang, B. Steffey, J. Cai, and O. Craciunescu. “Vaginal Dose and Toxicity With Image-Guided Brachytherapy.” In International Journal of Radiation Oncology*Biology*Physics, 87:S31–S31. Elsevier BV, 2013. https://doi.org/10.1016/j.ijrobp.2013.06.083.Full Text
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Ding, I., J. Chino, J. Cai, B. Steffy, S. Meltsner, and O. Craciunescu. “Volumetric Dose Summation Between Brachytherapy Fractions in Patients Treated for Cervical Cancer: Feasibility of Using Deformable Registration.” In International Journal of Radiation Oncology Biology Physics, 87:S413–14. ELSEVIER SCIENCE INC, 2013.Link to Item
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Abern, Michael, Zeljko Vujaskovic, Mark W. Dewhirst, Lan Lan, Oana I. Craciunescu, Paul Stauffer, and Brant Allen Inman. “Phase I clinical trial of external hyperthermia and intravesical mitomycin C to treat BCG-refractory bladder cancer.” In Journal of Clinical Oncology, Vol. 31. AMER SOC CLINICAL ONCOLOGY, 2013.Link to Item
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Adamson, J., Y. Yang, L. Rankine, J. Newton, J. Adamovics, O. Craciunescu, and M. Oldham. “Towards comprehensive characterization of Cs-137 Seeds using PRESAGE® dosimetry with optical tomography.” In J Phys Conf Ser, 444:12100, 2013. https://doi.org/10.1088/1742-6596/444/1/012100.Full Text Link to Item
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Cai, J., J. Chino, Y. Qin, T. R. De Oliveira, J. Adamson, B. Steffey, and O. Craciunescu. “Feasibility of MR-alone-based Brachytherapy Treatment Planning Using a Titanium Tandem and Ring Applicator for Cervical Cancer.” In International Journal of Radiation Oncology*Biology*Physics, 84:S803–S803. Elsevier BV, 2012. https://doi.org/10.1016/j.ijrobp.2012.07.2150.Full Text
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Chino, J. P., B. Steffey, J. Cai, J. Adamson, and O. Craciunescu. “Multicatheter Vaginal Balloon Brachytherapy: One Year's Clinical Experience.” In International Journal of Radiation Oncology*Biology*Physics, 84:S460–S460. Elsevier BV, 2012. https://doi.org/10.1016/j.ijrobp.2012.07.1219.Full Text
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Craciunescu, O. I., D. S. Yoo, J. D. Onxley, S. K. Das, N. Muradyan, E. Gu, J. Hoang, and D. M. Brizel. “Quantifying Temporal Fluctuations of DCE-MRI Extracted Parameters in Neck Nodal Metastases.” In International Journal of Radiation Oncology*Biology*Physics, 84:S755–S755. Elsevier BV, 2012. https://doi.org/10.1016/j.ijrobp.2012.07.2021.Full Text
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Zhu, L., O. Craciunescu, J. Cai, B. Steffey, J. Adamson, and J. P. Chino. “Urinary Catheterization Increases the Dose to Bowel During Vaginal Brachytherapy.” In International Journal of Radiation Oncology*Biology*Physics, 84:S455–S455. Elsevier BV, 2012. https://doi.org/10.1016/j.ijrobp.2012.07.1205.Full Text
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Vujaskovic, Z., O. I. Craciunescu, P. Stauffer, M. Carroll, L. Lan, M. Dewhirst, and B. A. Inman. “Pilot study of external hyperthermia and intravesical mitomycin-C to treat recurrent biadder cancer after failed standard therapy.” In Journal of Clinical Oncology, Vol. 28. AMER SOC CLINICAL ONCOLOGY, 2010.Link to Item
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Brizel, D., D. Yoo, M. Carrol, J. MacFall, D. Barboriak, G. Broadwater, and O. Craciunescu. “108 poster: Early Therapy Changes in Vascular Permeability Predict Long Term Outcome in Head and Neck Cancer.” In Radiotherapy and Oncology, 94:S42–S42. Elsevier BV, 2010. https://doi.org/10.1016/s0167-8140(15)34527-8.Full Text
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Mcmahon, R., T. Zhuang, B. Steffey, H. Song, and O. Craciunescu. “SU‐GG‐T‐58: Commissioning of Varian Ring & Tandem HDR Applicators: Reproducibility and Inter‐Observer Variability of Dwell Position Offsets.” In Medical Physics, 37:3197, 2010. https://doi.org/10.1118/1.3468444.Full Text
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Zhuang, T., B. Steffey, H. Song, and O. Craciunescu. “SU‐GG‐T‐69: Comparison of Three Optimization Methods of BrachyVision™ for IORT Using HDR and HAM Applicator.” In Medical Physics, 37:3200, 2010. https://doi.org/10.1118/1.3468455.Full Text
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Brizel, D. M., D. S. Yoo, N. Ready, J. P. Kirkpatrick, M. W. Dewhirst, R. L. Scher, E. Cleland, J. MacFall, D. Barboriak, and O. Craciunescu. “Synchronous Chemoradiation and Multiple Targeted Drugs for Advanced Head and Neck Cancer.” In International Journal of Radiation Oncology*Biology*Physics, 75:S175–76. Elsevier BV, 2009. https://doi.org/10.1016/j.ijrobp.2009.07.409.Full Text
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Craciunescu, O. I., J. M. Pepek, B. A. Steffey, J. Zhang, and E. L. Jones. “Relevance of Repeating the Planning CT for HDR Vaginal Cylinder Treatments: A Comparison of Intra Patient Variability and Inter User Contouring Variability.” In International Journal of Radiation Oncology*Biology*Physics, 75:S379–S379. Elsevier BV, 2009. https://doi.org/10.1016/j.ijrobp.2009.07.869.Full Text
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Kelsey, C. R., J. Chino, O. Craciunescu, B. Steffey, D. Rizzieri, M. Horwitz, G. Long, N. Chao, and L. Marks. “Severe Pulmonary Toxicity after Myeloablative Conditioning using Total Body Irradiation: An Assessment of Possible Predictive Factors.” In International Journal of Radiation Oncology*Biology*Physics, 75:S478–S478. Elsevier BV, 2009. https://doi.org/10.1016/j.ijrobp.2009.07.1091.Full Text
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Craciunescu, O., J. Macfall, B. Soher, P. Stauffer, P. Maccarini, E. Jones, N. Larrier, et al. “WE‐C‐BRC‐02: Combined Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE‐MRI) and Magnetic Resonance Thermal Imaging (MRTI) for Optimal Hyperthermia Treatment of Advanced Extremity Sarcomas: Fifteen Patients Update.” In Medical Physics, 36:2760, 2009. https://doi.org/10.1118/1.3182470.Full Text
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Craciunescu, O. I., D. Yoo, E. W. Cleland, D. P. Barboriak, M. Dolguikh, N. Muradyan, M. Kasibhatla, M. Carroll, and D. M. Brizel. “Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE-MRI) Assessment of Tumor Physiology in Head and Neck Cancer: A Comparison of Intra Patient and Inter Patient Variability.” In International Journal of Radiation Oncology*Biology*Physics, 72:S594–95. Elsevier BV, 2008. https://doi.org/10.1016/j.ijrobp.2008.06.204.Full Text
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Kim, D. W., K. Blackwell, Z. Vujaskovic, O. Craciunescu, P. Stauffer, V. Liotcheva, and E. Jones. “A Phase I/II Study of Neoadjuvant Liposomal Doxorubicin, Paclitaxel and Hyperthermia in Locally Advanced Breast Cancer.” In International Journal of Radiation Oncology*Biology*Physics, 72:S183–84. Elsevier BV, 2008. https://doi.org/10.1016/j.ijrobp.2008.06.751.Full Text
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Yoo, D. S., O. Craciunescu, E. Cleland, D. Barboriak, N. Muradyan, M. Dolguikh, J. P. Kirkpatrick, M. D. Carroll, and D. M. Brizel. “Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE-MRI) to Assess Changes in Tumor Physiology Caused by Molecular Targeted Agents in Locally Advanced Head and Neck Cancer (LAHNC).” In International Journal of Radiation Oncology*Biology*Physics, 72:S160–S160. Elsevier BV, 2008. https://doi.org/10.1016/j.ijrobp.2008.06.504.Full Text
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Chang, Z., O. Craciunescu, and F. Yin. “SU‐EE‐A4‐04: Accelerating Breast Dynamic Contrast Enhanced MRI with Efficient Multiple Acquisitions by SPEED Using Shared Information.” In Medical Physics, 35:2642, 2008. https://doi.org/10.1118/1.2961395.Full Text
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Cheng, K., V. Stakhursky, O. Craciunescu, P. Stauffer, M. Dewhirst, and S. Das. “SU‐GG‐T‐367: Fast Hyperthermia Temperature Optimization for Pelvic Carcinoma Patient Treated in Sigma‐Eye Applicator.” In Medical Physics, 35:2809–10, 2008. https://doi.org/10.1118/1.2962119.Full Text
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Cleland, E., D. Brizel, D. Yoo, M. Dolguikh, N. Muradyan, D. Barboriak, and O. Craciunescu. “SU‐GG‐J‐181: The Role of Voxel‐Based T10 Calculations in Determining Correct Pharmacokinetic Parameters for Head and Neck Tumors.” In Medical Physics, 35:2721, 2008. https://doi.org/10.1118/1.2961730.Full Text
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Jones, E. L., Z. Vujaskovic, O. Craciunescu, L. R. Prosnitz, L. Havrilesky, A. Secord, P. Stauffer, and M. W. Dewhirst. “International Phase III Trial of Chemoradiotherapy ± Hyperthermia for Locally Advanced Cervix Cancer: Interim Update on Toxicities.” In International Journal of Radiation Oncology*Biology*Physics, 69:S392–93. Elsevier BV, 2007. https://doi.org/10.1016/j.ijrobp.2007.07.1513.Full Text
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Craciunescu, O., B. Steffey, S. Yoo, N. Larrier, C. Paarz‐largay, K. Sullivan, and R. Prosnitz. “TU‐EE‐A2‐05: Challenges in Limiting Kidney Dose When Delivering Total Body Irradiation (TBI) for Patients with Severe Systemic Sclerosis (SSc).” In Medical Physics, 34:2568, 2007. https://doi.org/10.1118/1.2761426.Full Text
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Craciunescu, O., N. Muradyan, D. Barboriak, J. Macfall, and D. Brizel. “TH‐E‐M100J‐02: Potential of Dynamic Contrast Enhanced‐Magnetic Resonance Imaging (DCE‐MRI) Extracted Parameters to Estimate Treatment Response in Locally Advanced Head and Neck (LAHN) Cancer Patients.” In Medical Physics, 34:2649, 2007. https://doi.org/10.1118/1.2761755.Full Text
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Mbibi, O., O. Craciunescu, T. Fatunase, L. Marks, and F. Yin. “SU‐FF‐J‐105: Predicting Late Skin Effects Using Digital Infrared Imaging for Breast Cancer Patients Treated with Radiation.” In Medical Physics, 34:2392, 2007. https://doi.org/10.1118/1.2760610.Full Text
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Pursley, J., G. P. Beyer, O. Craciunescu, C. Fraisse, J. Carroll, and M. Oldham. “SU‐FF‐T‐98: Characterization of Buildup Effects in OneDosePlus MOSFET‐Based Dosimeters.” In Medical Physics, 34:2423, 2007. https://doi.org/10.1118/1.2760752.Full Text
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Craciunescu, O., T. Raidy, D. Brizel, K. Blackwell, Z. Vujaskovic, T. Wong, E. Jones, N. Larrier, J. Macfall, and M. Dewhirst. “SU‐FF‐J‐125: Therapy Assessment Using a Full Time Point (fTP) Pharmacokinetic Analysis of Dynamic Contrast‐Enhanced Magnetic Resonance Imaging (DCE‐MRI): Role of Region of Interest (ROI) Selection in Three Tumor Sites.” In Medical Physics, 33:2049, 2006. https://doi.org/10.1118/1.2240901.Full Text
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Mbibi, O., O. Craciunescu, T. Fatunase, L. Marks, and F. Yin. “SU‐DD‐A4‐01: Quantifying Skin Effects After Accelerated Partial Breast Irradiation Using Digital Infrared Imaging (DII): Preliminary Feasibility Data.” In Medical Physics, 33:1989, 2006. https://doi.org/10.1118/1.2240149.Full Text
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Craciunescu, O., K. Blackwell, T. Wong, E. Rosen, T. Raidy, E. Jones, Z. Vujaskovic, et al. “SU‐EE‐A2‐06: Non‐Contact, Non‐Invasive Breast Thermography Has Potential to Evaluate Treatment Response in Breast Cancer Patients.” In Medical Physics, 32:1898, 2005. https://doi.org/10.1118/1.1997458.Full Text
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Craciunescu, O., B. Steffey, C. Whiddon, and E. Halperin. “Rethinking total body irradiation (TBI) at Duke University Medical Center (DUMC).” In Medical Physics, 31:1916–1916. AMER ASSOC PHYSICISTS MEDICINE AMER INST PHYSICS, 2004.Link to Item
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Craciunescu, O. I., K. L. Blackwell, E. L. Jones, Z. Vujaskovic, E. L. Rosen, T. Z. Wong, J. R. MacFall, et al. “Contrast-enhanced magnetic resonance imaging (CE-MRI) parameters have predictive value in estimating response of locally advanced breast cancer (LABC) patients to neoadjuvant (NA) chemotherapy (CT) and hyperthermia (HT).” In Breast Cancer Research and Treatment, 88:S18–19. SPRINGER, 2004.Link to Item
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Craciunescu, O. I., S. K. Das, and L. B. Marks. “Influence of beam number and orientation on dose escalation for lung IMRT.” In Medical Physics, 30:1484–1484. AMER ASSOC PHYSICISTS MEDICINE AMER INST PHYSICS, 2003.Link to Item
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Das, S., M. Bell, S. Zhou, M. Miften, M. Munley, C. Whiddon, O. Craciunescu, et al. “Feasibility of functional image-guided radiotherapy evaluated using a novel heuristic fluence modulation algorithm.” In Medical Physics, 30:1335–1335. AMER ASSOC PHYSICISTS MEDICINE AMER INST PHYSICS, 2003.Link to Item
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Craciunescu, O. I., S. K. Das, R. L. McCauley, and T. V. Samulski. “Hyperthermia induced 3D temperature distribution in a human sarcoma with tumor perfusion reconstructed using fractal interpolation functions.” In Asme International Mechanical Engineering Congress and Exposition, Proceedings (Imece), 2000-F:59–65, 2000. https://doi.org/10.1115/IMECE2000-2222.Full Text
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Craciunescu, O., S. K. Das, and M. W. Dewhirst. “THREE-DIMENSIONAL MICROVASCULAR NETWORKS FRACTAL STRUCTURE: POTENTIAL FOR TISSUE CHARACTERIZATION?” In Asme International Mechanical Engineering Congress and Exposition, Proceedings (Imece), 1999-E:9–13, 1999. https://doi.org/10.1115/IMECE1999-0571.Full Text
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Craciunescu, O., and S. T. Clegg. “TOWARDS THE UNDERSTANDING OF BLOOD PERFUSION IN TUMOR VASCULAR NETWORKS USING CONTRAST-ENHANCED MRI AND INVASION PERCOLATION.” In Asme International Mechanical Engineering Congress and Exposition, Proceedings (Imece), 1998-E:143–47, 1998. https://doi.org/10.1115/IMECE1998-0809.Full Text
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Vergalasova, Irina, Kim Light, Junzo Chino, and Oana Craciunescu. “Simultaneous integrated boost (SIB) for treatment of gynecologic carcinoma: Intensity-modulated radiation therapy (IMRT) vs volumetric-modulated arc therapy (VMAT) radiotherapy.” In Med Dosim, 42:230–37, n.d. https://doi.org/10.1016/j.meddos.2017.05.002.Full Text Link to Item
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- Teaching & Mentoring
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Recent Courses
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Advising & Mentoring
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MS Thesis Advisor: 16 students:
Ome Mbibi (2007)
Esi Cleland (2008)
Jennifer Dixon Onxley(2012)
Linda Poplawski (2015)
Jeff Nawrocki (2015) awarded best presentation and a cash prize at the 2nd Annual Duke Cancer
Institute Scientific Retreat, November, 2014
Linda Lohman (2015),
Michelle Ronki (2018), awarded the Duke MP 2018 excellence in research award,
Xinyi Shen (2019) awarded the 2019 ABS Judith Stitt Best Abstract Award for her work in establishing
limits of error detection with novel in-vivo dosimeters in HDR brachytherapy (presented in
plenary talk),
Sabrina Campelo (2020) awarded the Dean’s Research Award for MS Fellowship to support our
research “3D Printing in Brachytherapy – Prototyping Applicators and Teaching Tools”. She
also received Co-Lab grant that will further allow us to improve the quality of gynecological
high dose rate (HDR) brachytherapy education creating modular 3D printed pelvic teaching
phantoms. She also received the first awarded Zachary Dean Shrock Memorial Scholarship from
the Medical Physics Program. Awarded P.E.O. Scholar 2022-2023.
Illyia Chibirev (2020)
Odunola Babawale (2021) awarded the Dean’s Research Award for MS Fellowship to support our
research “designing 3D printed brachytherapy teaching tools for radiation oncology residents”
Brian Shen (2021)
BillieAnn Radcliff (2022), co-mentor with Dr. Sheridan Meltsner
Yukun Yue (2022), DKU, co-mentor with Dr. Anna Rodrigues
Brett Eckroate (2022), co-mentor with Dr. Julie Raffi
Carolyn Eckrich (2023), co-mentor with Dr. Anna Rodrigues
MS, PhD Thesis Committees: 40 students, Duke and DKU
Chair, PhD Committee: Chunhao Wang (2016), Hope Pegues (2021)
Duke Radiation Oncology Medical Physics Residency Program: Past rotation supervisor for Brachytherapy, Linac QA, IMRT, TBI/TSI.
Available to mentor:
- Masters
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Teaching Activities
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Radiation Oncology, in-services, 2003-present: GYN planning, HDR emergency, TBI/TSI, modern HDR GYN brachytherapy
Radiation Oncology MD Residents, 2001-present: Teaching Special Procedures: TBI/TSI, Hyperthermia
Medical Physics Graduate Program, 2005- present: Teaching Practicum and Advanced Topics in Radiation Physics (Large Field Dosimetry and Brachytherapy), organizer MP Seminar (responsible for the Radiation Therapy track)
Medical Physics Residency Program, 2009-present: Involved in daily resident training mainly in areas of: GYN treatment planning, Linac and patient QA, brachytherapy. Past rotation supervisor for Linac QA, IMRT, TBI/TSI, Brachytherapy
National Education in Medical Physics: Invited Talks (for CME credits): Duke Radiation Oncology (2003-present), IMRT/IGRT Symposium (2008, 2010), RRS (2009), STM (2010), Varian International Brachytherapy Users Meeting (2010), STM(2011), AAPM(2012), AAPM (2013), AAPM(2014), WCB (2016), AAPM(2016), AAPM (2017), AAPM(2018)
DKU Spring GYN Brachytherapy Seminar: 2018-present
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- Scholarly, Clinical, & Service Activities
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Presentations & Appearances
- Developing Modern Brachytherapy Teaching Tools, in session Brachytherapy: Basics to Advancements. Spring AAPM 2022. AAPM. March 2022 2022
- Institutional experience with improving GYN HDR brachytherapy: 3D printed GYN training phantoms and efficient MR/CT-based planning flow”. NEAAPM 2021. 2021 2021
- “Working on MRI Simulator for Medical Physicists Who Are Not Trained in MRI “. AAPM. July 2018 2018
- “In-room imaging using film and CBCT”, . AAPM. July 2017 2017
- “Modern Intracavitary Gynecologic Brachytherapy”, . AAPM. July 2016 2016
- “CBCT Based Treatment Planning for GYN HDR Brachytherapy”, . World Congress of Brachytherapy. April 2016 2016
- “HDR Brachytherapy II: Integrating Imaging with HDR”. AAPM. July 2013 2013
- “Implementing MR-Guided Adaptive Brachytherapy for Cervical Cancer”, . AAPM. July 2013 2013
- “Image Guided Adaptive Brachytherapy for Cervical Cancer”. AAPM. July 2012 2012
- “Role and Limitations of Treatment Planning and Thermal Dosimetry in Clinical Hyperthermia”. Society for Thermal Medicine. April 2011 2011
- Imaging in Hyperthermia: From Treatment Planning and Delivery to Response and Prognosis”. Society for Thermal Medicine. April 2010 2010
- Towards patient specific, volumetric, imaged-based hyperthermia treatment planning, delivery and control”. Radiation Research Society Annual Meeting. 2008 2008
- “Role of DII in Estimating Response in Breast Cancer Patients with CW Recurrence Treated with Thermally Sensitive Liposomes Containing Doxorubicin and Hyperthermia”, . Joint Annual Meeting WCIO and STM. April 2007 2007
- Combined Dynamic-Enhanced Magnetic Resonance Imaging (DE-MRI) and Magnetic Resonance Thermal Imaging (MRTI) for Optimal Hyperthermia Treatment of Advanced Sarcomas of the Extremities. Society for Thermal Medicine. April 2006 2006
- Functional Imaging in Thermal Therapy of Breast Cancer. Society for Thermal Medicine . April 2006 2006
- Potential Use of Non-contact, Non-invasive Breast Thermography to Evaluate Treatment Response in Breast Cancer Patients”. Society for Thermal Medicine. April 2005 - April 2005 2005
- Using Contrast-Enhanced Magnetic Resonance Imaging (CE-MRI) to Characterize Tumor Changes during Neoadjuvant Treatment of Locally Advanced Breast Cancer Patients (LABC)”, . Society for Thermal Medicine. April 2005 - April 2005 2005
- Using Contrast-Enhanced Magnetic Resonance Imaging (CE-MRI) to Characterize Tumor Changes during Neoadjuvant Treatment of Locally Advanced Breast Cancer Patients (LABC)”. Society for Thermal Medicine. April 2005 2005
- Hyperthermia Thermal Modeling Project: The Duke Experience", . Nineteenth Annual Meeting of the North American Hyperthermia Society. 2001 - 2001 2001
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Outreach & Engaged Scholarship
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Service to the Profession
- Member. Global Clinical Education and Training Committee (GCETC). AAPM. 2021 2021
- PhD Thesis Examiner. Indian Institute of Technology Madras. 2016 - 2016 2016
- Associate Editor. Medical Physics Journal. 2015 2015
- Grant Reviewer. 2. Swiss National Science Foundation. 2015 - 2018 2015 - 2018
- Grant Reviewer. 1. Technology Foundation STW (member of the Netherlands Organization for Scientific Research), Utrecht, The Netherlands;. 2014 - 2014 2014
- Adhoc Consultant. Varian Medical Systems, Brachytherapy Division. 2012 - 2018 2012 - 2018
- Secretary/Treasurer. Society for Thermal Medicine. 2010 - 2013 2010 - 2013
- Member Financial Committee. Society for Thermal Medicine. 2008 - 2013 2008 - 2013
- Elected Council for Engineering/Physics. Society for Thermal Medicine. 2007 - 2009 2007 - 2009
- Adhoc Manuscript Reviewer. 2003 2003
- Session Chair. AAPM, STM, ASME. 2001 - 2018 2001 - 2018
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Service to Duke
- Medical Physics Graduate Program. Culture Committee. 2018 2018
- Medical Physics Graduate Program. MPAC. 2018 2018
- Medical Physics Graduate Program. “Cultural” Task Force. 2017 - 2017 2017
- Medical Physics Graduate Program. Co-Chair, Admission Committee. 2016 - 2018 2016 - 2018
- Medical Physics Graduate Program. Task Force: “Re-envisioning Medical Physics” . 2016 - 2017 2016 - 2017
- Screener/Interviewer (MMI). Admissions. Duke School of Medicine. 2016 2016
- Medical Physics Graduate Program. Admission Committee. 2014 - 2016 2014 - 2016
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Academic & Administrative Activities
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Administrative:
2013-present: member, Duke Medical Physics Graduate Program's Performance Committee2014-present, member, Duke Medical Physics Graduate Program’s Admission Committee
2014-present, member, Duke Medical Physics Graduate Program’s Admission Committee
2015-present, co-chair, Duke Medical Physics Graduate Program’s Admission Committee; 2017 interim chair
2015-2020, member, Duke School of Medicine application screener/MMI interviewer
2016-2017, member, Duke Medical Physics Graduate Program’s Task Force:
“Re-envisioning Medical Physics”
2016-2017, member, Duke Medical Physics Graduate Program’s “Cultural” Task Force.
2016-2019, co-organizer (RT Track) Distinguished Lecture Series for the Duke Medical Physics Graduate
Program
2018-present, elected at-large MPAC, Duke Medical Physics Graduate Program
2018-2019, chair of the Culture, Diversity and Equality Committee, Duke Medical Physics Graduate Program
(Resigned Feb. 2019 due to personal problems); 2021-presnt, co-chair of this committee.
2018-present, physics representative on the Diversity and Inclusion Committee, Department of Radiation
Oncology, Duke University Medical Center
2018-present, member of the DKU admission committee
2020-present, elected RT Track Director, Duke Medical Physics Graduate Program;
2021-2022: As RT Track Director I proposed and helped to get approval for the new 1 credit RT Elective on Treatment Planning instructed by Dr. Chunhao Wang.
2020-present, member External Liaison Committee, Duke Medical Physics Graduate Program
2020-present, member Curriculum Committee, Duke Medical Physics Graduate Program
2022: Invited Panelist for “Picture a Scientist” organized by the Radiation Oncology DEI group and the MP
Program Culture Committee
2020-present: Member (since inception) of the Radiation Oncology Department DEI group, Member of the
Physics DEI group (graduate of the Teach for Equity workshop organized by Duke SOM 2021)
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Clinical Activities
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Clinical Experience (general experience):
- 1. Accelerator acceptance, commissioning (Varian 600, 2100 EX), QA and imaging QA (Varian 600, 2100 EX and True Beam Series);
- 2. Acuity simulator with CBCT capability: commissioned brachy-specific CBCT techniques, QA
- 3. BK Focus 500 US commissioning and QA
- 4. TBI/TSI commissioning on 21EX and True Beam Series: standing and floor technique
- 5. IMRT commissioning (21EX series) and planning
- 6. Treatment Planning Systems proficiency: Eclipse, BrachyVision, VariSeed, Vitesse
- 7. 4DTC acquisition
- 8. SBRT for pelvic sites (GYN)
- 9. HDR afterloader acceptance, commissioning and QA (Varian and Nucletron equipment),
- 10. LDR/HDR commissioning of TPS, LDR prostate, LDR T&O, LDR interstitial, LDR eye plaques, HDR gyn, endobronchial, interstitial;
- 11. LDR and HDR applicator commissioning and QA
- 12. Commissioned several in-vivo dosimetry systems: MOSFETS, OneDose
- 13. Hyperthermia superficial and deep heating BSD equipment commissioning and QA
- 14. Other: MIM, Velocity
Clinical Experience (Leadership):
2003-2010; 2015(temp): Lead physicist TBI/TSI team:
- Commissioned TBI/TSI
- Developed clinical procedures
- In-service for therapists
- Rotation supervision for MP Residency program: large field dosimetry
- Wrote physics section of multi institutional SCOT protocol and served as main QA site and physics consultant for the protocol
- Implemented paperless documentation for these procedures
2003-present: Lead physicist on rotation basis of one of the linear accelerators
- Responsible for day-to-day correct function of the linac
- Performing QA after upgrades to hardware or software by manufacturer
- Check daily QA
- Perform monthly and annual QA and imaging QA
- Since 2006 trained MP students and residents on linac function and maintenance.
2008-2017: Lead physicist Brachytherapy team
- Commissioned Varian (GMPiX) HDR afterloaders
- Commissioned and configured TPS: BrachyVision, Vitesse
- Implemented MR-based treatment planning for GYN HDR applications
- Commissioned HDR applicators: T&O (LDR and HDR), T&R, vaginal stump cylinders, Miami, Capri, endobronchial catheters, HDR needles for GYN and prostate applications, HAM applicators, COMS Eye Plaques
- Commissioned US-based, real time HDR for prostate patients
- Calibrations for HDR source, LDR seeds and sources
- Implemented TG129 for LDR Eye Plaque Program
- Developed clinical and QA procedures for all HDR applications; Co-developed clinical and QA procedures for most LDR applications (over 40 procedures)
- Accepted and commissioned BK Focus 500 US system
- Active member of team: planning, QA, delivery
- Implemented paperless documentation for these procedures
- Schedule all procedures coverage
- Evaluated brachytherapy program at Duke Cancer Center Macon Pond and make recommendations
- Rotation supervisor for MP Residency program: Brachytherapy
- Guided, supervised and reviewed residents clinical research projects
- Invited symposia organizer and chair for AAPM 2012, 2013, 2014, 2015(deferred to a colleague due to inability to attend), 2016, ABS 2016
- Adhoc consultant for Varian Medical Systems Brachytherapy division (2012-present)
2009-2014: Lead physicist Sarcoma planning team; 2009-present: Lead physicist Gynecological Malignancies planning team
- Worked closely with dosimetry to develop simulation flows for the different type treatments
- Implemented IMRT and VMAT planning for GYN malignancies and sarcomas
- Actively involved in planning cases
- Trained dosimetrists on the team
- Check all IMRT/VMAT plans before presenting to physician
- Trained MP residents rotating in dosimetry
- Department morning talks on GYN Planning
- Guided, supervised and reviewed dosimetrists/residents clinical research projects
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