Oana Craciunescu | Scholars@Duke

Oana Craciunescu
Professor of Radiation Oncology

Current Research Interests

Brachytherapy clinical physics (MRI-based HDR, HDR treatment verification), role of DCE-MRI extracted parameters in radiation and thermal therapy, texture analysis, intelligent dose summation, imaged-based treatment planning techniques for gynecological malignancies (IMRT, VMAT, HDR).

Current Appointments & Affiliations

Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2021

Contact Information

40 Medicine Circle Duke South, Box 3295, Durham, NC 27710
Box 3295 Med Ctr, Durham, NC 27710
oana.craciunescu@duke.edu (919) 660-2192
Duke Medical Physics Graduate Program Faculty
Duke Scholars
Google Scholar
Radiation ONcology Physics Faculty/Staff

Background
Education, Training, & Certifications
- Faculty, Medical Physics Graduate Program, Duke University 2006
- American Board of Radiology (ABR), Medical Physics, American Board of Radiology 2006 - 2020
- Medical Physics Resident, Radiation Oncology Medical Physics Division, Duke University School of Medicine 2001 - 2003
- Ph.D., Duke University 1998
Previous Appointments & Affiliations
- Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2020
- Associate Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2011 - 2020
- Assistant Professor in Radiation Oncology, Radiation Oncology, Clinical Science Departments 2006 - 2011
- Assistant Clinical Professor in Radiation Oncology, Radiation Oncology, Clinical Science Departments 2003 - 2006
Leadership & Clinical Positions at Duke
- Duke University Medical Center                  Medical Physics Resident 2001-2003
  Duke University Medical Center                  Assistant Professor 2003-2011
  Duke University Medical Center                  Associate Professor 2011-2020
  Duke University Medical Center Professor 2020-present
  
  Clinical Experience (Leadership):
  
  2003-2010; 2015(temp): Lead physicist TBI/TSI team
  
  2003-present: Lead physicist on rotation basis of one of the linear accelerators
  
  2008-2017, 2020-2021: Lead physicist Brachytherapy team
  
  2009-2014: Lead physicist Sarcoma planning team;
  
  2009-present: Lead physicist Gynecological Malignancies planning team
Recognition
In the News
- SEP 15, 2020 AAPM Newsletter , September/October 2020, Vol 45, No., p. 37-38. 5
  
  Special Interest Feature: Women’s Professional Subcommittee
- JAN 3, 2018 Duke Health News and Media
  
  Study Shows Stem Cell Transplant Is Better Than Drug Therapy for Scleroderma
- DEC 11, 2004 Duke Health News and Media
  
  MRI Can Predict Breast Cancer's Response to Chemotherapy
Awards & Honors
Expertise
Subject Headings
Global Scholarship
- Expertise
  - Romania (Country)
Research
Selected Grants
- Cross-disciplinary Training in Medical Physics awarded by National Institutes of Health 2007 - 2013
- Unified Approach to Hyperthermia Modeling and Planning awarded by National Institutes of Health 2000 - 2002
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Shenker, Rachel, Carolyn Eckrich, Rachel D’Anna, Donna Niedzwiecki, Anna Rodrigues, Oana Craciunescu, and Junzo Chino. “Adaptive Positron Emission Tomography Radiation Therapy in Patients With Locally Advanced Vulvar Cancer: A Prospective Study.” Advances in Radiation Oncology 8, no. 4 (July 2023): 101208. https://doi.org/10.1016/j.adro.2023.101208.
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  - Meltsner, Sheridan G., Anna Rodrigues, Miguel A. Materin, David G. Kirsch, and Oana Craciunescu. “Transitioning from a COMS-based plaque brachytherapy program to using eye physics plaques and plaque simulator treatment planning system: A single institutional experience.” J Appl Clin Med Phys 24, no. 5 (May 2023): e13902. https://doi.org/10.1002/acm2.13902.
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  - Meltsner, Sheridan G., David G. Kirsch, Miguel A. Materin, Yongbok Kim, Yang Sheng, and Oana Craciunescu. “Dual-source strength seed loading for eye plaque brachytherapy using eye physics eye plaques: A feasibility study.” J Contemp Brachytherapy 14, no. 6 (December 2022): 590–600. https://doi.org/10.5114/jcb.2022.123979.
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  - Kheir, Wajiha J., Sandra S. Stinnett, Sheridan Meltsner, Ekaterina Semenova, Yvonne M. Mowery, Oana Craciunescu, David G. Kirsch, and Miguel A. Materin. “Preliminary Results of Uveal Melanoma Treated With Iodine-125 Plaques: Analysis of Disease Control and Visual Outcomes With 63 Gy to the Target Volume.” Adv Radiat Oncol 7, no. 2 (2022): 100869. https://doi.org/10.1016/j.adro.2021.100869.
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  - Arsenault, Theodore, Fang Fang Yin, Junzo Chino, Oana Craciunescu, and Jim Zheng Chang. “Evaluation of eddy current distortion and field inhomogeneity distortion corrections in MR diffusion imaging using log-demons DIR method.” Phys Med Biol 66, no. 3 (January 29, 2021): 035021. https://doi.org/10.1088/1361-6560/abcb20.
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  - Ackerson, Bradley G., Qiuwen Wu, Oana Craciunescu, Taofik Oyekunle, Donna Niedzwiecki, Jennie Gupton, Patrick Laug, et al. “Recumbent Total Skin Electron Beam Therapy.” Adv Radiat Oncol 6, no. 4 (2021): 100698. https://doi.org/10.1016/j.adro.2021.100698.
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  - Rodrigues, Anna, Kelly Loman, Jeff Nawrocki, Jenny K. Hoang, Zheng Chang, Yvonne M. Mowery, Taofik Oyekunle, Donna Niedzwiecki, David M. Brizel, and Oana Craciunescu. “Establishing ADC-Based Histogram and Texture Features for Early Treatment-Induced Changes in Head and Neck Squamous Cell Carcinoma.” Front Oncol 11 (2021): 708398. https://doi.org/10.3389/fonc.2021.708398.
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  - Subashi, Ergys, Corbin Jacobs, Rodney Hood, David G. Kirsch, and Oana Craciunescu. “A design process for a 3D printed patient-specific applicator for HDR brachytherapy of the orbit.” 3d Print Med 6, no. 1 (June 29, 2020): 15. https://doi.org/10.1186/s41205-020-00068-3.
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  - Campelo, Sabrina, Ergys Subashi, Sheridan G. Meltsner, Zheng Chang, Junzo Chino, and Oana Craciunescu. “Multimaterial three-dimensional printing in brachytherapy: Prototyping teaching tools for interstitial and intracavitary procedures in cervical cancers.” Brachytherapy 19, no. 6 (2020): 767–76. https://doi.org/10.1016/j.brachy.2020.07.013.
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  - Whitley, Melodi Javid, Willis Barrow, Oana I. Craciunescu, Michelle Pavlis, and David G. Kirsch. “Kaposi sarcoma in a patient with postpolio syndrome.” Cutis 104, no. 5 (November 2019): E20–22.
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  - Carpenter, David J., Corbin D. Jacobs, Terence Z. Wong, Oana Craciunescu, and Junzo P. Chino. “Changes on Midchemoradiation Therapy Fluorodeoxyglucose Positron Emission Tomography for Cervical Cancer Are Associated with Prognosis.” Int J Radiat Oncol Biol Phys 105, no. 2 (October 1, 2019): 356–66. https://doi.org/10.1016/j.ijrobp.2019.06.2506.
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  - Sullivan, Keith M., Ellen A. Goldmuntz, Lynette Keyes-Elstein, Peter A. McSweeney, Ashley Pinckney, Beverly Welch, Maureen D. Mayes, et al. “Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma.” N Engl J Med 378, no. 1 (January 4, 2018): 35–47. https://doi.org/10.1056/nejmoa1703327.
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  - Belley, Matthew D., Oana Craciunescu, Zheng Chang, Brian W. Langloss, Ian N. Stanton, Terry T. Yoshizumi, Michael J. Therien, and Junzo P. Chino. “Real-time dose-rate monitoring with gynecologic brachytherapy: Results of an initial clinical trial.” Brachytherapy 17, no. 6 (2018): 1023–29. https://doi.org/10.1016/j.brachy.2018.07.014.
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  - Brownstein, J., J. P. Chino, O. I. Craciunescu, and K. Light. “FDG Positron Emission Tomography as an Indicator of Myelosuppression in Women Undergoing Pelvic Chemoradiation Therapy.” Int J Radiat Oncol Biol Phys 96, no. 2S (October 1, 2016): E293. https://doi.org/10.1016/j.ijrobp.2016.06.1362.
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  - Natesan, D., O. I. Craciunescu, P. S. Lee, and J. P. Chino. “FDG Positron Emission Tomography (PET)/Computed Tomography Characteristics of Vulvar Cancer: Posttreatment PET Correlates With Clinical Outcomes.” Int J Radiat Oncol Biol Phys 96, no. 2S (October 1, 2016): S52–53. https://doi.org/10.1016/j.ijrobp.2016.06.137.
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  - Rodrigues, A., J. Nawrocki, K. Light, J. P. Chino, and O. I. Craciunescu. “Evaluation of Dose-Volume Metrics of an 18F-FDG Positron Emission Tomography Adaptive Treatment Planning Protocol for Gynecological Malignancies.” Int J Radiat Oncol Biol Phys 96, no. 2S (October 1, 2016): E296. https://doi.org/10.1016/j.ijrobp.2016.06.1368.
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  - Susko, M., O. I. Craciunescu, S. G. Meltsner, Y. Yang, B. Steffey, J. Cai, and J. P. Chino. “Vaginal Toxicity From Vaginal Brachytherapy and Capri-Based Systems.” Int J Radiat Oncol Biol Phys 96, no. 2S (October 1, 2016): E287–88. https://doi.org/10.1016/j.ijrobp.2016.06.1348.
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  - Vergalasova, I., K. Light, J. P. Chino, and O. I. Craciunescu. “Simultaneous Integrated Boost (SIB) for Treatment of Gynecological Malignancies: Intensity Modulated Radiation Therapy (IMRT) Versus Volumetric Modulated Arc Therapy (VMAT).” Int J Radiat Oncol Biol Phys 96, no. 2S (October 1, 2016): E677–78. https://doi.org/10.1016/j.ijrobp.2016.06.2324.
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  - Belley, M. D., A. Faught, B. Moore, E. Subashi, B. Langloss, M. J. Therien, T. T. Yoshizumi, J. P. Chino, and O. Craciunescu. “WE-DE-201-07: Measurement of Real-Time Dose for Tandem and Ovoid Brachytherapy Procedures Using a High Precision Optical Fiber Radiation Detector.” Med Phys 43, no. 6 (June 2016): 3809–10. https://doi.org/10.1118/1.4957812.
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  - Chino, J. P., M. D. Belley, Z. Chang, B. Langloss, T. T. Yoshizumi, M. J. Therien, and O. I. Craciunescu. “Real Time Dosimetry for Gynecologic Brachytherapy: Initial Results of a Prospective Clinical Trial (vol 93, pg S203, 2015).” International Journal of Radiation Oncology Biology Physics 95, no. 2 (June 1, 2016): 858–59.
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  - Craciunescu, O. “TU-FG-202-01: Modern Intracavitary GYN Brachytherapy.” Med Phys 43, no. 6 (June 2016): 3759. https://doi.org/10.1118/1.4957562.
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  - Loman, K., J. Nawrocki, J. Hoang, D. Yoo, Z. Chang, Y. Mowery, X. Li, B. Peterson, D. Brizel, and O. Craciunescu. “SU-F-R-15: Establishing Relevant ADC-Based Texture Analysis Metrics for Quantifying Early Treatment-Induced Changes in Head and Neck Squamous Cell Carcinoma.” Med Phys 43, no. 6 (June 2016): 3376. https://doi.org/10.1118/1.4955787.
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  - Yang, Y., J. Cai, S. Meltsner, Z. Chang, and O. Craciunescu. “SU-G-201-13: Investigation of Dose Variation Induced by HDR Ir-192 Source Global Shift Within the Varian Ring Applicator Using Monte Carlo Methods.” Medical Physics 43, no. 6 (June 2016): 3625–26. https://doi.org/10.1118/1.4956886.
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  - Susko, Matthew, Oana Craciunescu, Sheridan Meltsner, Yun Yang, Beverly Steffey, Jing Cai, and Junzo Chino. “Vaginal Dose Is Associated With Toxicity in Image Guided Tandem Ring or Ovoid-Based Brachytherapy.” Int J Radiat Oncol Biol Phys 94, no. 5 (April 1, 2016): 1099–1105. https://doi.org/10.1016/j.ijrobp.2015.12.360.
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  - Whitley, Melodi Javid, Adela R. Cardones, Oana I. Craciunescu, and David G. Kirsch. “Externally applied high-dose-rate brachytherapy for deeply invasive cutaneous squamous cell carcinoma in an older patient.” Pract Radiat Oncol 6, no. 4 (2016): e141–44. https://doi.org/10.1016/j.prro.2015.11.008.
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  - Tandberg, Daniel J., Oana Craciunescu, and Chris R. Kelsey. “Radiation Therapy for Cutaneous T-Cell Lymphomas.” Dermatol Clin 33, no. 4 (October 2015): 703–13. https://doi.org/10.1016/j.det.2015.05.006.
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  - Nawrocki, J., J. Chino, S. Das, and O. Craciunescu. “SU-E-J-262: Variability in Texture Analysis of Gynecological Tumors in the Context of An 18F-FDG PET Adaptive Protocol.” Med Phys 42, no. 6 (June 2015): 3327. https://doi.org/10.1118/1.4924348.
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  - Nawrocki, J., J. Chino, S. Das, and O. Craciunescu. “SU-E-J-249: Characterization of Gynecological Tumor Heterogeneity Using Texture Analysis in the Context of An 18F-FDG PET Adaptive Protocol.” Med Phys 42, no. 6 (June 2015): 3323. https://doi.org/10.1118/1.4924335.
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  - Poplawski, L., T. Li, J. Chino, and O. Craciunescu. “SU-E-J-105: Trusting Dose Deformation and Accumulation for GYN Brachytherapy.” Med Phys 42, no. 6 (June 2015): 3288. https://doi.org/10.1118/1.4924192.
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  - Siamakpour-Reihani, Sharareh, Kouros Owzar, Chen Jiang, Peter M. Scarbrough, Oana I. Craciunescu, Janet K. Horton, Holly K. Dressman, Kimberly L. Blackwell, and Mark W. Dewhirst. “Genomic profiling in locally advanced and inflammatory breast cancer and its link to DCE-MRI and overall survival.” Int J Hyperthermia 31, no. 4 (June 2015): 386–95. https://doi.org/10.3109/02656736.2015.1016557.
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  - Boyle, John, Oana Craciunescu, Beverly Steffey, Jing Cai, and Junzo Chino. “Methods, safety, and early clinical outcomes of dose escalation using simultaneous integrated and sequential boosts in patients with locally advanced gynecologic malignancies.” Gynecol Oncol 135, no. 2 (November 2014): 239–43. https://doi.org/10.1016/j.ygyno.2014.08.037.
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  - Hoang, Jenny K., Kingshuk Roy Choudhury, Jim Chang, Oana I. Craciunescu, David S. Yoo, and David M. Brizel. “Diffusion-weighted imaging for head and neck squamous cell carcinoma: quantifying repeatability to understand early treatment-induced change.” Ajr Am J Roentgenol 203, no. 5 (November 2014): 1104–8. https://doi.org/10.2214/AJR.14.12838.
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  - Zagar, Timothy M., Zeljko Vujaskovic, Silvia Formenti, Hope Rugo, Franco Muggia, Brigid O’Connor, Robert Myerson, et al. “Two phase I dose-escalation/pharmacokinetics studies of low temperature liposomal doxorubicin (LTLD) and mild local hyperthermia in heavily pretreated patients with local regionally recurrent breast cancer.” Int J Hyperthermia 30, no. 5 (August 2014): 285–94. https://doi.org/10.3109/02656736.2014.936049.
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  - Vidovic, A. K., T. Juang, S. Meltsner, J. Adamovics, J. Chino, B. Steffey, O. Craciunescu, and M. Oldham. “An investigation of a PRESAGE® in vivo dosimeter for brachytherapy.” Phys Med Biol 59, no. 14 (July 21, 2014): 3893–3905. https://doi.org/10.1088/0031-9155/59/14/3893.
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  - Onxley, Jennifer D., David S. Yoo, Naira Muradyan, James R. MacFall, David M. Brizel, and Oana I. Craciunescu. “Comprehensive population-averaged arterial input function for dynamic contrast-enhanced vmagnetic resonance imaging of head and neck cancer.” Int J Radiat Oncol Biol Phys 89, no. 3 (July 1, 2014): 658–65. https://doi.org/10.1016/j.ijrobp.2014.03.006.
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  - Craciunescu, O., D. Todor, and A. de Leeuw. “WE-F-BRD-01: HDR Brachytherapy II: Integrating Imaging with HDR.” Med Phys 41, no. 6 (June 2014): 513–14. https://doi.org/10.1118/1.4889467.
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  - Lu, S., L. Yuan, O. Craciunescu, Y. Ge, F. Yin, and Q. Wu. “TU-C-17A-11: Progressive Knowledge Modeling for Pelvic IMRT/VMAT Treatment Planning.” Med Phys 41, no. 6 (June 2014): 460. https://doi.org/10.1118/1.4889286.
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  - Nawrocki, J., J. Chino, K. Light, I. Vergalasova, and O. Craciunescu. “SU-E-J-124: FDG PET Metrics Analysis in the Context of An Adaptive PET Protocol for Node Positive Gynecologic Cancer Patients.” Med Phys 41, no. 6 (June 2014): 184. https://doi.org/10.1118/1.4888176.
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  - Inman, Brant A., Paul R. Stauffer, Oana A. Craciunescu, Paolo F. Maccarini, Mark W. Dewhirst, and Zeljko Vujaskovic. “A pilot clinical trial of intravesical mitomycin-C and external deep pelvic hyperthermia for non-muscle-invasive bladder cancer.” Int J Hyperthermia 30, no. 3 (May 2014): 171–75. https://doi.org/10.3109/02656736.2014.882021.
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  - Juang, Titania, Paul R. Stauffer, Oana A. Craciunescu, Paolo F. Maccarini, Yu Yuan, Shiva K. Das, Mark W. Dewhirst, Brant A. Inman, and Zeljko Vujaskovic. “Thermal dosimetry characteristics of deep regional heating of non-muscle invasive bladder cancer.” Int J Hyperthermia 30, no. 3 (May 2014): 176–83. https://doi.org/10.3109/02656736.2014.898338.
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  - Boyle, John M., Oana Craciunescu, Beverley Steffey, Jing Cai, and Junzo Chino. “Body mass index, dose to organs at risk during vaginal brachytherapy, and the role of three-dimensional CT-based treatment planning.” Brachytherapy 13, no. 4 (2014): 332–36. https://doi.org/10.1016/j.brachy.2013.12.002.
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  - Craciunescu, O., A. Gaspar, M. Trif, M. Moisei, A. Oancea, L. Moldovan, and O. Zarnescu. “Preparation and characterization of a collagen-liposome-chondroitin sulfate matrix with potential application for inflammatory disorders treatment.” Journal of Nanomaterials 2014 (January 1, 2014). https://doi.org/10.1155/2014/903691.
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  - Chukkala, D. P., K. Arunachalam, O. I. Craciunescu, P. Maccarini, P. R. Stauffer, and J. L. Schlorff. “An imaging study to assess displacement between brachytherapy applicator and chestwall during simultaneous thermobrachytherapy of cancer.” 2013 Ieee 2nd International Conference on Image Information Processing, Ieee Iciip 2013, December 1, 2013, 247–50. https://doi.org/10.1109/ICIIP.2013.6707592.
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  - Cabrera, Alvin R., Kyle C. Cuneo, Annick Desjardins, John H. Sampson, Frances McSherry, James E. Herndon, Katherine B. Peters, et al. “Concurrent stereotactic radiosurgery and bevacizumab in recurrent malignant gliomas: a prospective trial.” Int J Radiat Oncol Biol Phys 86, no. 5 (August 1, 2013): 873–79. https://doi.org/10.1016/j.ijrobp.2013.04.029.
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  - Craciunescu, O., J. Cai, and J. Chino. “TH-D-108-01: Implementing MR-Guided Adaptive Brachytherapy for Cervical Cancer.” Med Phys 40, no. 6Part33 (June 2013): 549. https://doi.org/10.1118/1.4815807.
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  - Vidovic, A., A. Juang, B. Steffey, S. Meltsner, J. Adamovics, J. Chino, O. Craciunescu, and M. Oldham. “SU-D-108-03: Evaluation of the Feasibility of a Novel Radiochromic Dosimetry System for In-Vivo Dose Verification in Organs at Risk in HDR Intracavitary Gynecological Brachytherapy.” Med Phys 40, no. 6Part3 (June 2013): 104. https://doi.org/10.1118/1.4814013.
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  - Ding, L., J. Chino, J. Cai, B. Steffey, S. Meltsner, Y. Yang, and O. Craciunescu. “SU‐E‐J‐88: Dose Summation Between Multimodality Treatments for Cervical Cancer.” Medical Physics 40, no. 6 (January 1, 2013): 170. https://doi.org/10.1118/1.4814300.
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  - Arunachalam, Kavitha, Oana I. Craciunescu, Edward J. Markewitz, Paolo F. Maccarini, Jaime L. Schlorff, and Paul R. Stauffer. “Preclinical assessment of comfort and secure fit of thermobrachytherapy surface applicator (TBSA) on volunteer subjects.” J Appl Clin Med Phys 13, no. 5 (September 6, 2012): 3845. https://doi.org/10.1120/jacmp.v13i5.3845.
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  - Adamson, Justus, Joseph Newton, Yun Yang, Beverly Steffey, Jing Cai, John Adamovics, Mark Oldham, Junzo Chino, and Oana Craciunescu. “Commissioning a CT-compatible LDR tandem and ovoid applicator using Monte Carlo calculation and 3D dosimetry.” Med Phys 39, no. 7Part1 (July 2012): 4515–23. https://doi.org/10.1118/1.4730501.
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  - Adamson, J., J. Newton, B. Steffey, J. Cai, J. Adamovics, M. Oldham, J. Chino, and O. Craciunescu. “SU-D-213AB-05: Commissioning a CT Compatible LDR T&O Applicator Using Analytical Calculation with ID and 3D Dosimetry.” Med Phys 39, no. 6Part3 (June 2012): 3612. https://doi.org/10.1118/1.4734665.
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  - Craciunescu, O., J. Cai, A. de Leeuw, and C. Kirisits. “TU-E-213CD-01: Image Guided Adaptive Brachytherapy for Cervical Cancer.” Med Phys 39, no. 6Part24 (June 2012): 3913. https://doi.org/10.1118/1.4735972.
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  - Onxley, J., D. Yoo, N. Muradyan, J. MacFall, D. Brizel, and O. Craciunescu. “SU-D-BRB-06: Comprehensive Population-Averaged Arterial Input Function (AIF) for DCE-MRI of Head and Neck Cancer.” Med Phys 39, no. 6Part3 (June 2012): 3615–16. https://doi.org/10.1118/1.4734678.
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  - Yuan, Yu, Cory Wyatt, Paolo Maccarini, Paul Stauffer, Oana Craciunescu, James Macfall, Mark Dewhirst, and Shiva K. Das. “A heterogeneous human tissue mimicking phantom for RF heating and MRI thermal monitoring verification.” Phys Med Biol 57, no. 7 (April 7, 2012): 2021–37. https://doi.org/10.1088/0031-9155/57/7/2021.
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  - Craciunescu, Oana I., David S. Yoo, Esi Cleland, Naira Muradyan, Madeline D. Carroll, James R. MacFall, Daniel P. Barboriak, and David M. Brizel. “Dynamic contrast-enhanced MRI in head-and-neck cancer: the impact of region of interest selection on the intra- and interpatient variability of pharmacokinetic parameters.” Int J Radiat Oncol Biol Phys 82, no. 3 (March 1, 2012): e345–50. https://doi.org/10.1016/j.ijrobp.2011.05.059.
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  - Yoo, David S., John P. Kirkpatrick, Oana Craciunescu, Gloria Broadwater, Bercedis L. Peterson, Madeline D. Carroll, Robert Clough, et al. “Prospective trial of synchronous bevacizumab, erlotinib, and concurrent chemoradiation in locally advanced head and neck cancer.” Clin Cancer Res 18, no. 5 (March 1, 2012): 1404–14. https://doi.org/10.1158/1078-0432.CCR-11-1982.
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  - Yuan, Yu, Kung-Shan Cheng, Oana I. Craciunescu, Paul R. Stauffer, Paolo F. Maccarini, Kavitha Arunachalam, Zeljko Vujaskovic, Mark W. Dewhirst, and Shiva K. Das. “Utility of treatment planning for thermochemotherapy treatment of nonmuscle invasive bladder carcinoma.” Med Phys 39, no. 3 (March 2012): 1170–81. https://doi.org/10.1118/1.3679839.
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  - McMahon, Ryan, Tingliang Zhuang, Beverly A. Steffey, Haijun Song, and Oana I. Craciunescu. “Commissioning of Varian ring & tandem HDR applicators: reproducibility and interobserver variability of dwell position offsets.” J Appl Clin Med Phys 12, no. 4 (November 15, 2011): 3447. https://doi.org/10.1120/jacmp.v12i4.3447.
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  - Kelsey, Chris R., Mitchell E. Horwitz, Junzo P. Chino, Oana Craciunescu, Beverly Steffey, Rodney J. Folz, Nelson J. Chao, David A. Rizzieri, and Lawrence B. Marks. “Severe pulmonary toxicity after myeloablative conditioning using total body irradiation: an assessment of risk factors.” Int J Radiat Oncol Biol Phys 81, no. 3 (November 1, 2011): 812–18. https://doi.org/10.1016/j.ijrobp.2010.06.058.
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  - Cabrera, A. R., O. Craciunescu, K. C. Cuneo, Z. Chang, and J. P. Kirkpatrick. “Evaluating Recurrent Gliomas with Diffusion-weighted MR Imaging Before and After Concurrent Radiosurgery and Bevacizumab.” International Journal of Radiation Oncology*Biology*Physics 81, no. 2 (October 2011): S793–S793. https://doi.org/10.1016/j.ijrobp.2011.06.1387.
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  - Das, S. K., D. S. Yoo, O. Craciunescu, J. Hoang, and D. M. Brizel. “The Use of Serial FDG-PET Scanning to Develop Metabolic Response Criteria to Chemoradiation in Head and Neck Cancer (HNC).” International Journal of Radiation Oncology*Biology*Physics 81, no. 2 (October 2011): S531–S531. https://doi.org/10.1016/j.ijrobp.2011.06.823.
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  - Craciunescu, Oana I., Beverly A. Steffey, Chris R. Kelsey, Nicole A. Larrier, Cathy J. Paarz-Largay, Robert G. Prosnitz, Nelson Chao, et al. “Renal shielding and dosimetry for patients with severe systemic sclerosis receiving immunoablation with total body irradiation in the scleroderma: cyclophosphamide or transplantation trial.” Int J Radiat Oncol Biol Phys 79, no. 4 (March 15, 2011): 1248–55. https://doi.org/10.1016/j.ijrobp.2010.05.036.
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  - Li, Zhen, Martin Vogel, Paolo F. Maccarini, Vadim Stakhursky, Brian J. Soher, Oana I. Craciunescu, Shiva Das, Omar A. Arabe, Williams T. Joines, and Paul R. Stauffer. “Improved hyperthermia treatment control using SAR/temperature simulation and PRFS magnetic resonance thermal imaging.” Int J Hyperthermia 27, no. 1 (2011): 86–99. https://doi.org/10.3109/02656736.2010.501509.
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  - McMahon, R., T. Zhuang, B. A. Steffey, H. Song, and O. I. Craciunescu. “Commissioning of Varian ring & tandem HDR applicators: Reproducibility and interobserver variability of dwell position offsets.” Journal of Applied Clinical Medical Physics 12, no. 4 (January 1, 2011): 50–62. https://doi.org/10.1120/jacmp.v12i4.3447.
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  - Pierquet, M., O. Craciunescu, B. Steffey, H. Song, and M. Oldham. “On the Feasibility of Verification of 3D Dosimetry Near Brachytherapy Sources Using PRESAGE/Optical-CT.” J Phys Conf Ser 250, no. 1 (December 7, 2010): 120911–15. https://doi.org/10.1088/1742-6596/250/1/012091.
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  - Popescu, Maria-Cristina, Cornelia Vasile, and Oana Craciunescu. “Structural analysis of some soluble elastins by means of FT-IR and 2D IR correlation spectroscopy.” Biopolymers 93, no. 12 (December 2010): 1072–84. https://doi.org/10.1002/bip.21524.
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  - Craciunescu, Oana, David Brizel, Esi Cleland, David Yoo, Naira Muradyan, Madeline Carroll, Daniel Barboriak, and James MacFall. “Dynamic contrast enhanced-MRI in head and neck cancer patients: Variability of the precontrast longitudinal relaxation time (T10).” Med Phys 37, no. 6Part1 (June 2010): 2683–92. https://doi.org/10.1118/1.3427487.
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  - Arunachalam, K., P. F. Maccarini, O. I. Craciunescu, J. L. Schlorff, and P. R. Stauffer. “Thermal characteristics of thermobrachytherapy surface applicators for treating chest wall recurrence.” Phys Med Biol 55, no. 7 (April 7, 2010): 1949–69. https://doi.org/10.1088/0031-9155/55/7/011.
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  - Craciunescu, Oana I., Donald E. Thrall, Zeljko Vujaskovic, and Mark W. Dewhirst. “Magnetic resonance imaging: a potential tool in assessing the addition of hyperthermia to neoadjuvant therapy in patients with locally advanced breast cancer.” Int J Hyperthermia 26, no. 7 (2010): 625–37. https://doi.org/10.3109/02656736.2010.499526.
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  - Stauffer, Paul R., Paolo Maccarini, Kavitha Arunachalam, Oana Craciunescu, Chris Diederich, Titania Juang, Francesca Rossetto, et al. “Conformal microwave array (CMA) applicators for hyperthermia of diffuse chest wall recurrence.” Int J Hyperthermia 26, no. 7 (2010): 686–98. https://doi.org/10.3109/02656736.2010.501511.
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  - Vujaskovic, Zeljko, Dong W. Kim, Ellen Jones, Lan Lan, Linda McCall, Mark W. Dewhirst, Oana Craciunescu, et al. “A phase I/II study of neoadjuvant liposomal doxorubicin, paclitaxel, and hyperthermia in locally advanced breast cancer.” Int J Hyperthermia 26, no. 5 (2010): 514–21. https://doi.org/10.3109/02656731003639364.
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  - Zagar, Timothy M., James R. Oleson, Zeljko Vujaskovic, Mark W. Dewhirst, Oana I. Craciunescu, Kimberly L. Blackwell, Leonard R. Prosnitz, and Ellen L. Jones. “Hyperthermia for locally advanced breast cancer.” Int J Hyperthermia 26, no. 7 (2010): 618–24. https://doi.org/10.3109/02656736.2010.501051.
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  - Zagar, Timothy M., James R. Oleson, Zeljko Vujaskovic, Mark W. Dewhirst, Oana I. Craciunescu, Kimberly L. Blackwell, Leonard R. Prosnitz, and Ellen L. Jones. “Hyperthermia combined with radiation therapy for superficial breast cancer and chest wall recurrence: a review of the randomised data.” Int J Hyperthermia 26, no. 7 (2010): 612–17. https://doi.org/10.3109/02656736.2010.487194.
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  - Moldovan, L., O. Craciunescu, E. I. Oprita, M. Balan, and O. Zarnescu. “Collagen-chondroitin sulfate-hydroxyapatite porous composites: preparation, characterization and in vitro biocompatibility testing.” Romanian Biotechnological Letters 14, no. 3 (November 17, 2009): 4459–66.
  - Craciunescu, Oana I., Paul R. Stauffer, Brian J. Soher, Cory R. Wyatt, Omar Arabe, Paolo Maccarini, Shiva K. Das, et al. “Accuracy of real time noninvasive temperature measurements using magnetic resonance thermal imaging in patients treated for high grade extremity soft tissue sarcomas.” Med Phys 36, no. 11 (November 2009): 4848–58. https://doi.org/10.1118/1.3227506.
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  - Viglianti, Benjamin L., Michael Lora-Michiels, Jeanie M. Poulson, Lan Lan, Daohai Yu, Linda Sanders, Oana Craciunescu, et al. “Dynamic contrast-enhanced magnetic resonance imaging as a predictor of clinical outcome in canine spontaneous soft tissue sarcomas treated with thermoradiotherapy.” Clin Cancer Res 15, no. 15 (August 1, 2009): 4993–5001. https://doi.org/10.1158/1078-0432.CCR-08-2222.
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  - Stakhursky, Vadim L., Omar Arabe, Kung-Shan Cheng, James Macfall, Paolo Maccarini, Oana Craciunescu, Mark Dewhirst, Paul Stauffer, and Shiva K. Das. “Real-time MRI-guided hyperthermia treatment using a fast adaptive algorithm.” Phys Med Biol 54, no. 7 (April 7, 2009): 2131–45. https://doi.org/10.1088/0031-9155/54/7/019.
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  - Craciunescu, O., C. Tardei, and L. Moldovana. “Nano-β-tricalcium phosphate/collagen materials with improved biostability for bone replacement applications.” Proceedings of Spie the International Society for Optical Engineering 7297 (March 23, 2009). https://doi.org/10.1117/12.823658.
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  - Stauffer, Pr, Oi Craciunescu, P. Maccarini, C. Wyatt, K. Arunachalam, O. Arabe, V. Stakhursky, et al. “Clinical Utility of Magnetic Resonance Thermal Imaging (MRTI) For Realtime Guidance of Deep Hyperthermia.” Proc Spie Int Soc Opt Eng 7181 (February 25, 2009). https://doi.org/10.1117/12.812188.
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  - Arunachalam, Kavitha, Oana I. Craciunescu, Paolo F. Maccarini, Jaime L. Schlorff, Edward Markowitz, and Paul R. Stauffer. “Progress on ThermoBrachytherapy Surface Applicator for Superficial Tissue Diseases.” Proc Spie Int Soc Opt Eng 7181 (February 12, 2009). https://doi.org/10.1117/12.809493.
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  - Bratu, M. M., F. Roncea, L. Moldovan, O. Craciunescu, T. Negreanu-Pîrjol, and G. Tarǎlungǎ. “In vitro evaluation of new topical preparation based on polyphenols, zinc and a matrix animal components.” Archives of the Balkan Medical Union 44, no. 1 (January 1, 2009): 31–34.
  - Craciunescu, Oana I., Kimberly L. Blackwell, Ellen L. Jones, James R. Macfall, Daohai Yu, Zeljko Vujaskovic, Terence Z. Wong, et al. “DCE-MRI parameters have potential to predict response of locally advanced breast cancer patients to neoadjuvant chemotherapy and hyperthermia: a pilot study.” Int J Hyperthermia 25, no. 6 (2009): 405–15. https://doi.org/10.1080/02656730903022700.
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  - Maccarini, Paolo F., Kavitha Arunachalam, Titania Juang, Valeria De Luca, Sneha Rangarao, Daniel Neumann, Carlos Daniel Martins, Oana Craciunescu, and Paul R. Stauffer. “Shaping and resizing of multifed slot radiators used in conformal microwave antenna arrays for hyperthermia treatment of large superficial diseases.” Int Conf Electromagn Adv Appl, 2009. https://doi.org/10.1109/ICEAA.2009.5297299.
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  - Tardei, C., F. Grigore, L. Moldovan, O. Craciunescu, and E. I. Oprita. “Preparation and characterization of bioresorbable synthetic scaffolds composed from different beta-tricalcium phosphate powders and collagen.” A Global Road Map for Ceramic Materials and Technologies: Forecasting the Future of Ceramics, International Ceramic Federation 2nd International Congress on Ceramics, Icc 2008, Final Programme, December 1, 2008.
  - Trif, Mihaela, Lucia Moldovan, Magdalena Moisei, Oana Craciunescu, and Otilia Zarnescu. “Liposomes-entrapped chondroitin sulphate: ultrastructural characterization and in vitro biocompatibility.” Micron 39, no. 7 (October 2008): 1042–45. https://doi.org/10.1016/j.micron.2008.01.008.
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  - Cheng, Kung-Shan, Vadim Stakhursky, Oana I. Craciunescu, Paul Stauffer, Mark Dewhirst, and Shiva K. Das. “Fast temperature optimization of multi-source hyperthermia applicators with reduced-order modeling of 'virtual sources'.” Phys Med Biol 53, no. 6 (March 21, 2008): 1619–35. https://doi.org/10.1088/0031-9155/53/6/008.
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  - Oprita, E. I., L. Moldovan, O. Craciunescu, and O. Zarnescu. “In vitro behaviour of osteoblast cells seeded into a COL/β-TCP composite scaffold.” Central European Journal of Biology 3, no. 1 (March 1, 2008): 31–37. https://doi.org/10.2478/s11535-007-0047-5.
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  - Craciunescu, O., M. Lungu, O. Zarnescu, A. Gaspar, and L. Moldovan. “Polyurethane-based materials covered with natural polymers for medical applications.” Materiale Plastice 45, no. 2 (January 1, 2008): 163–66.
  - Moldovan, L., O. Craciunescu, M. Balan, A. Gaspar, and E. Gherghina. “The purification, physico-chemical characterization and bioactivity of polysaccharides from Viscum album.” Revista De Chimie 59, no. 9 (January 1, 2008): 1022–25. https://doi.org/10.37358/rc.08.9.1961.
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  - Moldovan, L., O. Craciunescu, O. Zarnescu, D. Macocinschi, and D. Bojin. “Preparation and characterization of new biocompatibilizecd polymeric materials for medical use.” Journal of Optoelectronics and Advanced Materials 10, no. 4 (January 1, 2008): 942–47.
  - Moldovan, L., O. Craciunescu, M. Balan, E. I. Oprita, and O. Zarnescu. “Synthesis and biocompatibility of porous collagen/chondroitin sulfate/hydroxyapatite composites for bone tissue engineering.” European Cells and Materials 14, no. SUPPL.1 (August 1, 2007): 80.
  - Craciunescu, O., L. M. Stefan, M. Balan, and L. Moldovan. “Evaluation of the radioprotective activity of new green tea-collagen materials.” Journal of Optoelectronics and Advanced Materials 9, no. 8 (January 1, 2007): 2602–7.
  - Thrall, D. E., M. W. Dewhirst, E. L. Jones, Z. Vujaskovic, D. Yu, and O. I. Craciunescu. “A clinically proven, prospective, thermal dose descriptor exists [4].” Clinical Cancer Research 12, no. 6 (March 15, 2006): 1944–46. https://doi.org/10.1158/1078-0432.CCR-05-2446.
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  - Oprita, E. I., L. Moldovan, O. Craciunescu, W. Buzgariu, C. Tardei, and O. Zarnescu. “A bioactive collagen-β tricalcium phosphate scaffold for tissue engineering.” Central European Journal of Biology 1, no. 1 (March 1, 2006): 61–72. https://doi.org/10.2478/s11535-006-0005-7.
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  - Das, Shiva K., James Macfall, Robert McCauley, Oana Craciunescu, Mark W. Dewhirst, and Thaddeus V. Samulski. “Improved magnetic resonance thermal imaging by combining proton resonance frequency shift (PRFS) and apparent diffusion coefficient (ADC) data.” Int J Hyperthermia 21, no. 7 (November 2005): 657–67. https://doi.org/10.1080/02656730500186346.
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  - Craciunescu, O. I., E. L. Jones, K. L. Blackwell, T. Z. Wong, E. L. Rosen, Z. Vujaskovic, J. R. MacFall, et al. “Characterizing tumor changes during neoadjuvant treatment of locally advanced breast cancer patients (LABC) using dynamic-enhanced magnetic resonance imaging (DE-MRI).” Proc. Spie Int. Soc. Opt. Eng. (Usa) 5698, no. 1 (2005): 116–25. https://doi.org/10.1117/12.591173.
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  - Das, Shiva K., Alan H. Baydush, Sumin Zhou, Moyed Miften, Xiaoli Yu, Oana Craciunescu, Mark Oldham, et al. “Predicting radiotherapy-induced cardiac perfusion defects.” Med Phys 32, no. 1 (January 2005): 19–27. https://doi.org/10.1118/1.1823571.
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  - Das, S. K., M. M. Miften, S. Zhou, M. Bell, M. T. Munley, C. S. Whiddon, O. Craciunescu, et al. “Feasibility of optimizing the dose distribution in lung tumors using fluorine-18-fluorodeoxyglucose positron emission tomography and single photon emission computed tomography guided dose prescriptions.” Med Phys 31, no. 6 (June 2004): 1452–61. https://doi.org/10.1118/1.1750991.
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  - Craciunescu, O. I., S. K. Das, T. Z. Wong, and T. V. Samulski. “Fractal reconstruction of breast perfusion before and after hyperthermia treatments.” Asme International Mechanical Engineering Congress and Exposition, Proceedings, January 1, 2002, 207–11. https://doi.org/10.1115/IMECE2002-33692.
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  - Craciunescu, O. I., S. K. Das, T. Z. Wong, and T. V. Samulski. “Fractal reconstruction of breast perfusion before and after hyperthermia treatments.” American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed 54 (2002): 207–11.
  - Craciunescu, O. I., B. W. Raaymakers, A. N. Kotte, S. K. Das, T. V. Samulski, and J. J. Lagendijk. “Discretizing large traceable vessels and using DE-MRI perfusion maps yields numerical temperature contours that match the MR noninvasive measurements.” Med Phys 28, no. 11 (November 2001): 2289–96. https://doi.org/10.1118/1.1408619.
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  - Craciunescu, O. I., and S. T. Clegg. “Pulsatile blood flow effects on temperature distribution and heat transfer in rigid vessels.” J Biomech Eng 123, no. 5 (October 2001): 500–505. https://doi.org/10.1115/1.1392318.
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  - Craciunescu, O. I., S. K. Das, J. M. Poulson, and T. V. Samulski. “Three-dimensional tumor perfusion reconstruction using fractal interpolation functions.” Ieee Trans Biomed Eng 48, no. 4 (April 2001): 462–73. https://doi.org/10.1109/10.915713.
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  - Craciunescu, O. I., B. W. Raaymakers, A. N. T. J. Kotte, S. K. Das, T. V. Samulski, and J. J. W. Lagendijk. “A case study of hyperthermia induced temperature computations in human sarcomas using discrete vasculature and relative perfusion maps.” American Society of Mechanical Engineers, Heat Transfer Division, (Publication) Htd 370 (January 1, 2001): 29–35.
  - Craciunescu, O. I., S. K. Das, R. L. McCauley, J. R. MacFall, and T. V. Samulski. “3D numerical reconstruction of the hyperthermia induced temperature distribution in human sarcomas using DE-MRI measured tissue perfusion: validation against non-invasive MR temperature measurements.” Int J Hyperthermia 17, no. 3 (2001): 221–39. https://doi.org/10.1080/02656730110041149.
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  - Craciunescu, O. I., S. K. Das, and T. V. Samulski. “Piecewise fractal interpolation models to reconstruct the three-dimensional tumor perfusion.” Annual International Conference of the Ieee Engineering in Medicine and Biology Proceedings 1 (December 1, 2000): 292–305.
  - Craciunescu, O. I., T. V. Samulski, J. R. MacFall, and S. T. Clegg. “Perturbations in hyperthermia temperature distributions associated with counter-current flow: numerical simulations and empirical verification.” Ieee Trans Biomed Eng 47, no. 4 (April 2000): 435–43. https://doi.org/10.1109/10.828143.
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  - Craciunescu, O., S. K. Das, and M. W. Dewhirst. “Three-dimensional microvascular networks fractal structure: potential for tissue characterization?” American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed 44 (December 1, 1999): 9–13.
  - Craciunescu, O. I., S. K. Das, and S. T. Clegg. “Dynamic contrast-enhanced MRI and fractal characteristics of percolation clusters in two-dimensional tumor blood perfusion.” J Biomech Eng 121, no. 5 (October 1999): 480–86. https://doi.org/10.1115/1.2835076.
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  - Craciunescu, O. I., L. E. Howle, and S. T. Clegg. “Experimental evaluation of the thermal properties of two tissue equivalent phantom materials.” Int J Hyperthermia 15, no. 6 (1999): 509–18. https://doi.org/10.1080/026567399285503.
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  - Craciunescu, O., and S. T. Clegg. “Towards the understanding of blood perfusion in tumor vascular networks using contrast-enhanced MRI and invasion percolation.” American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed 40 (December 1, 1998): 143–47.
  - Craciunescu, O., and S. T. Clegg. “Perturbations of large vessels on induced temperature distributions. Part A: Three-dimensional simulation study.” American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed 37 (December 1, 1997): 193–98.
  - Craciunescu, O., A. Bejan, D. G. Cacuci, and W. Schutz. “Time-dependent interaction between water at supercritical pressures and a hot surface.” Numerical Heat Transfer; Part A: Applications 30, no. 6 (January 1, 1996): 535–53. https://doi.org/10.1080/10407789608913856.
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- Book Sections
  - Dewhirst, M., P. R. Stauffer, S. Das, O. I. Craciunescu, and Z. Vujaskovic. “Hyperthermia.” In Clinical Radiation Oncology, 381-398.e6, 2015. https://doi.org/10.1016/B978-0-323-24098-7.00021-6.
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  - Dewhirst, M., S. Das, P. Stauffer, O. Craciunescu, Z. Vujaskovic, and D. Thrall. “Hyperthermia.” In Clinical Radiation Oncology: Third Edition, 385–403, 2012. https://doi.org/10.1016/B978-1-4377-1637-5.00021-3.
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- Conference Papers
  - Eckroate, B., J. Raffi, R. Venkataraman, Y. Kim, D. Ayala-peacock, and O. Craciunescu. “Development of An Original Multi-Modality Gynecologic Brachytherapy Phantom.” In Medical Physics, 49:E815–E815, 2022.
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  - Shenker, R. F., A. Rodrigues, C. Eckrich, R. D’Anna, D. Niedzwiecki, O. I. Craciunescu, and J. P. Chino. “Adaptive PET Radiation Therapy in Patients with Locally Advanced Vulvar Cancer: A Prospective Study.” In International Journal of Radiation Oncology Biology Physics, 114:E279–E279, 2022.
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  - Radcliffe, B., S. Meltsner, Z. Chang, J. Chino, M. Huang, and O. Craciunescu. “A Retrospective Dose Analysis of High-Dose Rate (HDR) Tandem and Ovoid and Interstitial Needle Cervical Brachytherapy Cases with a Model-Based Dose Calculation Algorithm (MBDCA).” In Medical Physics, Vol. 48, 2021.
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  - Shen, B., Z. Chang, C. Wang, S. Meltsner, J. Chino, and O. Craciunescu. “Uncertainties in MR-To-MR Image Registration for HDR Cervical Brachytherapy.” In Medical Physics, Vol. 48, 2021.
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  - Campelo, S., E. Subashi, Z. Chang, S. G. Meltsner, J. P. Chino, and O. I. Craciunescu. “Multi-material 3D Printing in Brachytherapy– Prototyping Teaching Tools.” In International Journal of Radiation Oncology*Biology*Physics, 108:e437–e437. Elsevier BV, 2020. https://doi.org/10.1016/j.ijrobp.2020.07.2525.
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  - Ackerson, B., Q. Wu, O. I. Craciunescu, D. Niedzwiecki, T. Oyekunle, and C. R. Kelsey. “Treatment of Mycosis Fungoides using a Recumbent Total Skin Electron Beam Technique: A Comparison of Dosimetric and Clinical Outcomes.” In International Journal of Radiation Oncology Biology Physics, 108:S167–S167, 2020.
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  - Arsenault, T., F. Yin, J. Chino, O. Craciunescu, and Z. Chang. “EPI Distortion Correction Using Log-Demons Method in MR Diffusion Tensor Images.” In Medical Physics, 47:E531–E531, 2020.
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  - Campelo, S., E. Subashi, Z. Chang, S. Meltsner, J. Chino, and O. Craciunescu. “The Development of a Multi-Material 3D Printed Brachytherapy Training Phantom for Enhanced Resident Training.” In Medical Physics, 47:E858–E858, 2020.
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  - Chibirev, I., S. Meltsner, Z. Chang, M. Materin, D. Kirsch, and O. Craciunescu. “Eye Plaque Brachytherapy Treatment Planning with Fundus Image-Based Tumor Modeling: Retrospective Institutional Experience.” In Medical Physics, 47:E780–E780, 2020.
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  - Rodrigues, A., O. Craciunescu, Q. Wu, and N. Larrier. “Standard of Care Total Body Irradiation for Scleroderma: Duke Institutional Implementation.” In Medical Physics, 47:E490–E490, 2020.
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  - Eclov, N., O. Craciunescu, J. Chino, and Z. Chang. “Evaluation of an MRI-Positive HDR Lumen Marker for HDR Brachytherapy Treatment Planning.” In Medical Physics, 46:E309–E309. WILEY, 2019.
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  - Shen, X., A. Rodrigues, J. Chino, O. Craciunescu, and S. Stephens. “Investigation of Contour-Based Deformable Image Registration cbDIR of Pre-Brachytherapy MRI pbMRI for Target Definition in HDR Cervical Cancer Treatments.” In Medical Physics, 46:E96–E96. WILEY, 2019.
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  - Shen, X., O. Craciunescu, M. Rokni, P. Maccarini, B. Langloss, M. Therien, T. Yoshizumi, and J. Chino. “Simulation-Based Ability of a Real-Time Fiber-Optic Detector to Catch Gross Errors in T& O HDR Brachytherapy Treatments.” In Medical Physics, 46:E197–E197. WILEY, 2019.
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  - Wu, Q., O. I. Craciunescu, A. Rodrigues, S. G. Meltsner, C. Wang, H. Gao, and C. R. Kelsey. “Commissioning and Clinical Implementation of a Laying Down Technique for Total Skin Irradiation.” In International Journal of Radiation Oncology*Biology*Physics, 102:e480–e480. Elsevier BV, 2018. https://doi.org/10.1016/j.ijrobp.2018.07.1371.
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  - Craciunescu, O., J. Cai, C. Glide-Hurst, and Y. Yang. “Technical and Professional Preparations for Medical Physicists in the Upcoming MRgRT Era.” In Medical Physics, 45:E696–E696. WILEY, 2018.
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  - Rokni, M., P. Maccarini, X. Shen, B. Moore, B. Langloss, A. Rodrigues, M. Belley, et al. “It is About (real) Time to Verify HDR Treatments: Duke Solution Using Nano-Fiber Optic Detector.” In Medical Physics, 45:E574–E574. WILEY, 2018.
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  - Wu, Q., O. Craciunescu, A. Rodrigues, S. Meltsner, C. Wang, H. Gao, and C. Kelsey. “Commissioning of a Laying Down Technique for Total Skin Irradiation (TSI).” In Medical Physics, 45:E623–E623. WILEY, 2018.
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  - Chino, J. P., J. A. Dorth, G. Suneja, A. Rodrigues, K. Light, and O. I. Craciunescu. “IDEAL-GYN (Integrated Dose Escalation for Advanced Localized Gynecologic Cancers): A Dose Escalation Trial of Bowel Sparing Simultaneous Integrated Boosts for Node Positive Cervical and Vulvar Cancers.” In International Journal of Radiation Oncology*Biology*Physics, 99:E286–E286. Elsevier BV, 2017. https://doi.org/10.1016/j.ijrobp.2017.06.1285.
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  - Daley, L. A., O. I. Craciunescu, G. Suneja, K. Light, A. Rodrigues, and J. P. Chino. “Simultaneous Integrated Parametrial/Sidewall Boosts for Cervical Cancer: Late Toxicity and Outcomes.” In International Journal of Radiation Oncology*Biology*Physics, 99:E288–E288. Elsevier BV, 2017. https://doi.org/10.1016/j.ijrobp.2017.06.1290.
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  - Langloss, Brian, Ian Stanton, Matthew Belley, John Dooley, Sha Chang, Oana Craciunescu, Junzo Chino, Terry Yoshizumi, and Michael Therien. “Radiation detection and dosimetry using Y2O3:Eu/Li nanoscintillators.” In Abstracts of Papers of the American Chemical Society, Vol. 254. AMER CHEMICAL SOC, 2017.
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  - Damato, Antonio, O. Craciunescu, I. Buzurovic, and G. Cohen. “HDR Brachytherapy: Treatment Verification Methods.” In Medical Physics, 44:3070–3070. WILEY, 2017.
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  - Rodrigues, A., S. Yoon, N. Morales-Medina, M. Oldham, J. Adamovics, S. Meltsner, and O. Craciunescu. “3D Printing and 3D Dosimetry for LDR I-125 Eye Plaque Brachytherapy Quality Assurance.” In Medical Physics, Vol. 44. WILEY, 2017.
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  - Rokni, M., A. Rodrigues, B. Moore, T. Yoshizumi, and O. Craciunescu. “Feasibility of Real-Time Dosimetry for HDR Prostate Brachytherapy Using a Nano-Fiber Optic Detector.” In Medical Physics, 44:3153–3153. WILEY, 2017.
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  - Wang, C., F. Yin, O. Craciunescu, A. Faught, and Z. Chang. “Commissioning of a 3.0T MR Simulator Dedicated for Radiation Oncology Application.” In Medical Physics, Vol. 44. WILEY, 2017.
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  - Natesan, D., O. I. Craciunescu, P. S. Lee, and J. P. Chino. “FDG Positron Emission Tomography (PET)/Computed Tomography Characteristics of Vulvar Cancer: Posttreatment PET Correlates With Clinical Outcomes.” In International Journal of Radiation Oncology Biology Physics, 96:S52–53, 2016.
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  - Vergalasova, I., K. Light, J. P. Chino, and O. I. Craciunescu. “Simultaneous Integrated Boost (SIB) for Treatment of Gynecological Malignancies: Intensity Modulated Radiation Therapy (IMRT) Versus Volumetric Modulated Arc Therapy (VMAT).” In International Journal of Radiation Oncology Biology Physics, 96:E677–78, 2016.
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  - Nawrocki, J., J. P. Chino, and O. I. Craciunescu. “Isolating Texture Features of Gynecological Tumors With High Variability in the Context of an 18F-FDG PET Adaptive Protocol.” In International Journal of Radiation Oncology*Biology*Physics, 93:E614–15. Elsevier BV, 2015. https://doi.org/10.1016/j.ijrobp.2015.07.2116.
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  - Boyle, J. M., J. A. Dorth, O. I. Craciunescu, K. Light, J. R. Roper, and J. P. Chino. “Simultaneous Integrated Boost to Pelvic and Para-Aortic Nodes From Cervical Cancer Improves the Dosimetric Therapeutic Ratio.” In International Journal of Radiation Oncology*Biology*Physics, 90:S482–83. Elsevier BV, 2014. https://doi.org/10.1016/j.ijrobp.2014.05.1494.
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  - Chino, J. P., J. Nawrocki, I. Vergalasova, K. Light, and O. Craciunescu. “A Prospective Evaluation of FDG PET Adapted IMRT for Node-Positive Gynecologic Cancers.” In International Journal of Radiation Oncology*Biology*Physics, 90:S184–S184. Elsevier BV, 2014. https://doi.org/10.1016/j.ijrobp.2014.05.708.
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  - Nawrocki, J., J. Chino, K. Light, I. Vergalasova, and O. Craciunescu. “FDG PET Metrics Analysis in the Context of An Adaptive PET Protocol for Node Positive Gynecologic Cancer Patients.” In Medical Physics, 41:184–184. WILEY, 2014.
    Link to Item
  - Boyle, J. M., J. Dorth, O. Craciunescu, B. Steffey, K. Light, and J. Chino. “Initial Safety and Feasibility of Dose Escalation Using a Simultaneous Integrated Boost in Patients With Locally Advanced Gynecologic Malignancies.” In International Journal of Radiation Oncology*Biology*Physics, 87:S425–26. Elsevier BV, 2013. https://doi.org/10.1016/j.ijrobp.2013.06.1121.
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  - Chino, J. P., S. Meltsner, Y. Yang, B. Steffey, J. Cai, and O. Craciunescu. “Vaginal Dose and Toxicity With Image-Guided Brachytherapy.” In International Journal of Radiation Oncology*Biology*Physics, 87:S31–S31. Elsevier BV, 2013. https://doi.org/10.1016/j.ijrobp.2013.06.083.
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  - Ding, I., J. Chino, J. Cai, B. Steffy, S. Meltsner, and O. Craciunescu. “Volumetric Dose Summation Between Brachytherapy Fractions in Patients Treated for Cervical Cancer: Feasibility of Using Deformable Registration.” In International Journal of Radiation Oncology Biology Physics, 87:S413–14. ELSEVIER SCIENCE INC, 2013.
    Link to Item
  - Abern, Michael, Zeljko Vujaskovic, Mark W. Dewhirst, Lan Lan, Oana I. Craciunescu, Paul Stauffer, and Brant Allen Inman. “Phase I clinical trial of external hyperthermia and intravesical mitomycin C to treat BCG-refractory bladder cancer.” In Journal of Clinical Oncology, Vol. 31. AMER SOC CLINICAL ONCOLOGY, 2013.
    Link to Item
  - Adamson, J., Y. Yang, L. Rankine, J. Newton, J. Adamovics, O. Craciunescu, and M. Oldham. “Towards comprehensive characterization of Cs-137 Seeds using PRESAGE® dosimetry with optical tomography.” In J Phys Conf Ser, 444:12100, 2013. https://doi.org/10.1088/1742-6596/444/1/012100.
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  - Cai, J., J. Chino, Y. Qin, T. R. De Oliveira, J. Adamson, B. Steffey, and O. Craciunescu. “Feasibility of MR-alone-based Brachytherapy Treatment Planning Using a Titanium Tandem and Ring Applicator for Cervical Cancer.” In International Journal of Radiation Oncology*Biology*Physics, 84:S803–S803. Elsevier BV, 2012. https://doi.org/10.1016/j.ijrobp.2012.07.2150.
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  - Chino, J. P., B. Steffey, J. Cai, J. Adamson, and O. Craciunescu. “Multicatheter Vaginal Balloon Brachytherapy: One Year's Clinical Experience.” In International Journal of Radiation Oncology*Biology*Physics, 84:S460–S460. Elsevier BV, 2012. https://doi.org/10.1016/j.ijrobp.2012.07.1219.
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  - Craciunescu, O. I., D. S. Yoo, J. D. Onxley, S. K. Das, N. Muradyan, E. Gu, J. Hoang, and D. M. Brizel. “Quantifying Temporal Fluctuations of DCE-MRI Extracted Parameters in Neck Nodal Metastases.” In International Journal of Radiation Oncology*Biology*Physics, 84:S755–S755. Elsevier BV, 2012. https://doi.org/10.1016/j.ijrobp.2012.07.2021.
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  - Zhu, L., O. Craciunescu, J. Cai, B. Steffey, J. Adamson, and J. P. Chino. “Urinary Catheterization Increases the Dose to Bowel During Vaginal Brachytherapy.” In International Journal of Radiation Oncology*Biology*Physics, 84:S455–S455. Elsevier BV, 2012. https://doi.org/10.1016/j.ijrobp.2012.07.1205.
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  - Vujaskovic, Z., O. I. Craciunescu, P. Stauffer, M. Carroll, L. Lan, M. Dewhirst, and B. A. Inman. “Pilot study of external hyperthermia and intravesical mitomycin-C to treat recurrent biadder cancer after failed standard therapy.” In Journal of Clinical Oncology, Vol. 28. AMER SOC CLINICAL ONCOLOGY, 2010.
    Link to Item
  - Brizel, D., D. Yoo, M. Carrol, J. MacFall, D. Barboriak, G. Broadwater, and O. Craciunescu. “108 poster: Early Therapy Changes in Vascular Permeability Predict Long Term Outcome in Head and Neck Cancer.” In Radiotherapy and Oncology, 94:S42–S42. Elsevier BV, 2010. https://doi.org/10.1016/s0167-8140(15)34527-8.
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  - Mcmahon, R., T. Zhuang, B. Steffey, H. Song, and O. Craciunescu. “SU‐GG‐T‐58: Commissioning of Varian Ring & Tandem HDR Applicators: Reproducibility and Inter‐Observer Variability of Dwell Position Offsets.” In Medical Physics, 37:3197, 2010. https://doi.org/10.1118/1.3468444.
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  - Zhuang, T., B. Steffey, H. Song, and O. Craciunescu. “SU‐GG‐T‐69: Comparison of Three Optimization Methods of BrachyVision™ for IORT Using HDR and HAM Applicator.” In Medical Physics, 37:3200, 2010. https://doi.org/10.1118/1.3468455.
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  - Brizel, D. M., D. S. Yoo, N. Ready, J. P. Kirkpatrick, M. W. Dewhirst, R. L. Scher, E. Cleland, J. MacFall, D. Barboriak, and O. Craciunescu. “Synchronous Chemoradiation and Multiple Targeted Drugs for Advanced Head and Neck Cancer.” In International Journal of Radiation Oncology*Biology*Physics, 75:S175–76. Elsevier BV, 2009. https://doi.org/10.1016/j.ijrobp.2009.07.409.
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  - Craciunescu, O. I., J. M. Pepek, B. A. Steffey, J. Zhang, and E. L. Jones. “Relevance of Repeating the Planning CT for HDR Vaginal Cylinder Treatments: A Comparison of Intra Patient Variability and Inter User Contouring Variability.” In International Journal of Radiation Oncology*Biology*Physics, 75:S379–S379. Elsevier BV, 2009. https://doi.org/10.1016/j.ijrobp.2009.07.869.
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  - Kelsey, C. R., J. Chino, O. Craciunescu, B. Steffey, D. Rizzieri, M. Horwitz, G. Long, N. Chao, and L. Marks. “Severe Pulmonary Toxicity after Myeloablative Conditioning using Total Body Irradiation: An Assessment of Possible Predictive Factors.” In International Journal of Radiation Oncology*Biology*Physics, 75:S478–S478. Elsevier BV, 2009. https://doi.org/10.1016/j.ijrobp.2009.07.1091.
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  - Craciunescu, O., J. Macfall, B. Soher, P. Stauffer, P. Maccarini, E. Jones, N. Larrier, et al. “WE‐C‐BRC‐02: Combined Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE‐MRI) and Magnetic Resonance Thermal Imaging (MRTI) for Optimal Hyperthermia Treatment of Advanced Extremity Sarcomas: Fifteen Patients Update.” In Medical Physics, 36:2760, 2009. https://doi.org/10.1118/1.3182470.
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  - Craciunescu, O. I., D. Yoo, E. W. Cleland, D. P. Barboriak, M. Dolguikh, N. Muradyan, M. Kasibhatla, M. Carroll, and D. M. Brizel. “Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE-MRI) Assessment of Tumor Physiology in Head and Neck Cancer: A Comparison of Intra Patient and Inter Patient Variability.” In International Journal of Radiation Oncology*Biology*Physics, 72:S594–95. Elsevier BV, 2008. https://doi.org/10.1016/j.ijrobp.2008.06.204.
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  - Kim, D. W., K. Blackwell, Z. Vujaskovic, O. Craciunescu, P. Stauffer, V. Liotcheva, and E. Jones. “A Phase I/II Study of Neoadjuvant Liposomal Doxorubicin, Paclitaxel and Hyperthermia in Locally Advanced Breast Cancer.” In International Journal of Radiation Oncology*Biology*Physics, 72:S183–84. Elsevier BV, 2008. https://doi.org/10.1016/j.ijrobp.2008.06.751.
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  - Yoo, D. S., O. Craciunescu, E. Cleland, D. Barboriak, N. Muradyan, M. Dolguikh, J. P. Kirkpatrick, M. D. Carroll, and D. M. Brizel. “Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE-MRI) to Assess Changes in Tumor Physiology Caused by Molecular Targeted Agents in Locally Advanced Head and Neck Cancer (LAHNC).” In International Journal of Radiation Oncology*Biology*Physics, 72:S160–S160. Elsevier BV, 2008. https://doi.org/10.1016/j.ijrobp.2008.06.504.
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  - Chang, Z., O. Craciunescu, and F. Yin. “SU‐EE‐A4‐04: Accelerating Breast Dynamic Contrast Enhanced MRI with Efficient Multiple Acquisitions by SPEED Using Shared Information.” In Medical Physics, 35:2642, 2008. https://doi.org/10.1118/1.2961395.
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  - Cheng, K., V. Stakhursky, O. Craciunescu, P. Stauffer, M. Dewhirst, and S. Das. “SU‐GG‐T‐367: Fast Hyperthermia Temperature Optimization for Pelvic Carcinoma Patient Treated in Sigma‐Eye Applicator.” In Medical Physics, 35:2809–10, 2008. https://doi.org/10.1118/1.2962119.
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  - Cleland, E., D. Brizel, D. Yoo, M. Dolguikh, N. Muradyan, D. Barboriak, and O. Craciunescu. “SU‐GG‐J‐181: The Role of Voxel‐Based T10 Calculations in Determining Correct Pharmacokinetic Parameters for Head and Neck Tumors.” In Medical Physics, 35:2721, 2008. https://doi.org/10.1118/1.2961730.
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  - Jones, E. L., Z. Vujaskovic, O. Craciunescu, L. R. Prosnitz, L. Havrilesky, A. Secord, P. Stauffer, and M. W. Dewhirst. “International Phase III Trial of Chemoradiotherapy ± Hyperthermia for Locally Advanced Cervix Cancer: Interim Update on Toxicities.” In International Journal of Radiation Oncology*Biology*Physics, 69:S392–93. Elsevier BV, 2007. https://doi.org/10.1016/j.ijrobp.2007.07.1513.
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  - Craciunescu, O., B. Steffey, S. Yoo, N. Larrier, C. Paarz‐largay, K. Sullivan, and R. Prosnitz. “TU‐EE‐A2‐05: Challenges in Limiting Kidney Dose When Delivering Total Body Irradiation (TBI) for Patients with Severe Systemic Sclerosis (SSc).” In Medical Physics, 34:2568, 2007. https://doi.org/10.1118/1.2761426.
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  - Craciunescu, O., N. Muradyan, D. Barboriak, J. Macfall, and D. Brizel. “TH‐E‐M100J‐02: Potential of Dynamic Contrast Enhanced‐Magnetic Resonance Imaging (DCE‐MRI) Extracted Parameters to Estimate Treatment Response in Locally Advanced Head and Neck (LAHN) Cancer Patients.” In Medical Physics, 34:2649, 2007. https://doi.org/10.1118/1.2761755.
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  - Mbibi, O., O. Craciunescu, T. Fatunase, L. Marks, and F. Yin. “SU‐FF‐J‐105: Predicting Late Skin Effects Using Digital Infrared Imaging for Breast Cancer Patients Treated with Radiation.” In Medical Physics, 34:2392, 2007. https://doi.org/10.1118/1.2760610.
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  - Pursley, J., G. P. Beyer, O. Craciunescu, C. Fraisse, J. Carroll, and M. Oldham. “SU‐FF‐T‐98: Characterization of Buildup Effects in OneDosePlus MOSFET‐Based Dosimeters.” In Medical Physics, 34:2423, 2007. https://doi.org/10.1118/1.2760752.
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  - Craciunescu, O., T. Raidy, D. Brizel, K. Blackwell, Z. Vujaskovic, T. Wong, E. Jones, N. Larrier, J. Macfall, and M. Dewhirst. “SU‐FF‐J‐125: Therapy Assessment Using a Full Time Point (fTP) Pharmacokinetic Analysis of Dynamic Contrast‐Enhanced Magnetic Resonance Imaging (DCE‐MRI): Role of Region of Interest (ROI) Selection in Three Tumor Sites.” In Medical Physics, 33:2049, 2006. https://doi.org/10.1118/1.2240901.
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  - Mbibi, O., O. Craciunescu, T. Fatunase, L. Marks, and F. Yin. “SU‐DD‐A4‐01: Quantifying Skin Effects After Accelerated Partial Breast Irradiation Using Digital Infrared Imaging (DII): Preliminary Feasibility Data.” In Medical Physics, 33:1989, 2006. https://doi.org/10.1118/1.2240149.
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  - Craciunescu, O., K. Blackwell, T. Wong, E. Rosen, T. Raidy, E. Jones, Z. Vujaskovic, et al. “SU‐EE‐A2‐06: Non‐Contact, Non‐Invasive Breast Thermography Has Potential to Evaluate Treatment Response in Breast Cancer Patients.” In Medical Physics, 32:1898, 2005. https://doi.org/10.1118/1.1997458.
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  - Craciunescu, O., B. Steffey, C. Whiddon, and E. Halperin. “Rethinking total body irradiation (TBI) at Duke University Medical Center (DUMC).” In Medical Physics, 31:1916–1916. AMER ASSOC PHYSICISTS MEDICINE AMER INST PHYSICS, 2004.
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  - Craciunescu, O. I., K. L. Blackwell, E. L. Jones, Z. Vujaskovic, E. L. Rosen, T. Z. Wong, J. R. MacFall, et al. “Contrast-enhanced magnetic resonance imaging (CE-MRI) parameters have predictive value in estimating response of locally advanced breast cancer (LABC) patients to neoadjuvant (NA) chemotherapy (CT) and hyperthermia (HT).” In Breast Cancer Research and Treatment, 88:S18–19. SPRINGER, 2004.
    Link to Item
  - Craciunescu, O. I., S. K. Das, and L. B. Marks. “Influence of beam number and orientation on dose escalation for lung IMRT.” In Medical Physics, 30:1484–1484. AMER ASSOC PHYSICISTS MEDICINE AMER INST PHYSICS, 2003.
    Link to Item
  - Das, S., M. Bell, S. Zhou, M. Miften, M. Munley, C. Whiddon, O. Craciunescu, et al. “Feasibility of functional image-guided radiotherapy evaluated using a novel heuristic fluence modulation algorithm.” In Medical Physics, 30:1335–1335. AMER ASSOC PHYSICISTS MEDICINE AMER INST PHYSICS, 2003.
    Link to Item
  - Craciunescu, O. I., S. K. Das, R. L. McCauley, and T. V. Samulski. “Hyperthermia induced 3D temperature distribution in a human sarcoma with tumor perfusion reconstructed using fractal interpolation functions.” In Asme International Mechanical Engineering Congress and Exposition, Proceedings (Imece), 2000-F:59–65, 2000. https://doi.org/10.1115/IMECE2000-2222.
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  - Craciunescu, O., S. K. Das, and M. W. Dewhirst. “THREE-DIMENSIONAL MICROVASCULAR NETWORKS FRACTAL STRUCTURE: POTENTIAL FOR TISSUE CHARACTERIZATION?” In Asme International Mechanical Engineering Congress and Exposition, Proceedings (Imece), 1999-E:9–13, 1999. https://doi.org/10.1115/IMECE1999-0571.
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  - Craciunescu, O., and S. T. Clegg. “TOWARDS THE UNDERSTANDING OF BLOOD PERFUSION IN TUMOR VASCULAR NETWORKS USING CONTRAST-ENHANCED MRI AND INVASION PERCOLATION.” In Asme International Mechanical Engineering Congress and Exposition, Proceedings (Imece), 1998-E:143–47, 1998. https://doi.org/10.1115/IMECE1998-0809.
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  - Vergalasova, Irina, Kim Light, Junzo Chino, and Oana Craciunescu. “Simultaneous integrated boost (SIB) for treatment of gynecologic carcinoma: Intensity-modulated radiation therapy (IMRT) vs volumetric-modulated arc therapy (VMAT) radiotherapy.” In Med Dosim, 42:230–37, n.d. https://doi.org/10.1016/j.meddos.2017.05.002.
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Teaching & Mentoring
Recent Courses
Advising & Mentoring
- MS Thesis Advisor: 16 students:
  
  Ome Mbibi (2007)
  
  Esi Cleland (2008)
  
  Jennifer Dixon Onxley(2012)
  
  Linda Poplawski (2015)
  
  Jeff Nawrocki (2015) awarded best presentation and a cash prize at the 2nd Annual Duke Cancer
  
              Institute Scientific Retreat, November, 2014
  
  Linda Lohman (2015),
  
  Michelle Ronki (2018), awarded the Duke MP 2018 excellence in research award,
  
  Xinyi Shen (2019) awarded the 2019 ABS Judith Stitt Best Abstract Award for her work in establishing
  
              limits of error detection with novel in-vivo dosimeters in HDR brachytherapy (presented in
  
              plenary talk),
  
  Sabrina Campelo (2020) awarded the Dean’s Research Award for MS Fellowship to support our
  
              research “3D Printing in Brachytherapy – Prototyping Applicators and Teaching Tools”. She
  
              also received Co-Lab grant that will further allow us to improve the quality of gynecological
  
              high dose rate (HDR) brachytherapy education creating modular 3D printed pelvic teaching
  
              phantoms. She also received the first awarded Zachary Dean Shrock Memorial Scholarship from
  
              the Medical Physics Program. Awarded P.E.O. Scholar 2022-2023.
  
  Illyia Chibirev (2020)
  
  Odunola Babawale (2021) awarded the Dean’s Research Award for MS Fellowship to support our
  
              research “designing 3D printed brachytherapy teaching tools for radiation oncology residents”
  
  Brian Shen (2021)
  
  BillieAnn Radcliff (2022), co-mentor with Dr. Sheridan Meltsner
  
  Yukun Yue (2022), DKU, co-mentor with Dr. Anna Rodrigues
  
  Brett Eckroate (2022), co-mentor with Dr. Julie Raffi
  
  Carolyn Eckrich (2023), co-mentor with Dr. Anna Rodrigues
  
  MS, PhD Thesis Committees: 40 students, Duke and DKU
  
  Chair, PhD Committee: Chunhao Wang (2016), Hope Pegues (2021)
  
  Duke Radiation Oncology Medical Physics Residency Program: Past rotation supervisor for Brachytherapy, Linac QA, IMRT, TBI/TSI.
Available to mentor:
- Masters
Teaching Activities
- Radiation Oncology, in-services, 2003-present: GYN planning, HDR emergency, TBI/TSI, modern HDR GYN brachytherapy
  
  Radiation Oncology MD Residents, 2001-present: Teaching Special Procedures: TBI/TSI, Hyperthermia
  
  Medical Physics Graduate Program, 2005- present: Teaching Practicum and Advanced Topics in Radiation Physics (Large Field Dosimetry and Brachytherapy), organizer MP Seminar (responsible for the Radiation Therapy track)
  
  Medical Physics Residency Program, 2009-present: Involved in daily resident training mainly in areas of: GYN treatment planning, Linac and patient QA, brachytherapy. Past rotation supervisor for Linac QA, IMRT, TBI/TSI, Brachytherapy
  
  National Education in Medical Physics: Invited Talks (for CME credits): Duke Radiation Oncology (2003-present), IMRT/IGRT Symposium (2008, 2010), RRS (2009), STM (2010), Varian International Brachytherapy Users Meeting (2010), STM(2011), AAPM(2012), AAPM (2013), AAPM(2014), WCB (2016), AAPM(2016), AAPM (2017), AAPM(2018)
  
  DKU Spring GYN Brachytherapy Seminar: 2018-present
Scholarly, Clinical, & Service Activities
Presentations & Appearances
Outreach & Engaged Scholarship
- Organizer. WAM, WiSE. Duke WAM. March 9, 2018 - March 9, 2018 2018
Service to the Profession
Service to Duke
Academic & Administrative Activities
- Administrative:
  
  2013-present: member, Duke Medical Physics Graduate Program's Performance Committee
  
  2014-present, member, Duke Medical Physics Graduate Program’s Admission Committee
  
  2014-present, member, Duke Medical Physics Graduate Program’s Admission Committee
  
  2015-present, co-chair, Duke Medical Physics Graduate Program’s Admission Committee; 2017 interim chair
  
  2015-2020, member, Duke School of Medicine application screener/MMI interviewer
  
  2016-2017, member, Duke Medical Physics Graduate Program’s Task Force:
  
  “Re-envisioning Medical Physics”
  
  2016-2017, member, Duke Medical Physics Graduate Program’s “Cultural” Task Force.
  
  2016-2019, co-organizer (RT Track) Distinguished Lecture Series for the Duke Medical Physics Graduate
  
              Program
  
  2018-present, elected at-large MPAC, Duke Medical Physics Graduate Program
  
  2018-2019, chair of the Culture, Diversity and Equality Committee, Duke Medical Physics Graduate Program
  
              (Resigned Feb. 2019 due to personal problems); 2021-presnt, co-chair of this committee.
  
  2018-present, physics representative on the Diversity and Inclusion Committee, Department of Radiation
  
              Oncology, Duke University Medical Center
  
  2018-present, member of the DKU admission committee
  
  2020-present, elected RT Track Director, Duke Medical Physics Graduate Program;
  
  2021-2022: As RT Track Director I proposed and helped to get approval for the new 1 credit RT Elective on Treatment Planning instructed by Dr. Chunhao Wang.
  
  2020-present, member External Liaison Committee, Duke Medical Physics Graduate Program
  
  2020-present, member Curriculum Committee, Duke Medical Physics Graduate Program
  
  2022: Invited Panelist for “Picture a Scientist” organized by the Radiation Oncology DEI group and the MP
  
  Program Culture Committee
  
  2020-present: Member (since inception) of the Radiation Oncology Department DEI group, Member of the
  
              Physics DEI group (graduate of the Teach for Equity workshop organized by Duke SOM 2021)
Clinical Activities
- Clinical Experience (general experience):
  1. 1. Accelerator acceptance, commissioning (Varian 600, 2100 EX), QA and imaging QA (Varian 600, 2100 EX and True Beam Series);
  2. 2. Acuity simulator with CBCT capability: commissioned brachy-specific CBCT techniques, QA
  3. 3. BK Focus 500 US commissioning and QA
  4. 4. TBI/TSI commissioning on 21EX and True Beam Series: standing and floor technique
  5. 5. IMRT commissioning (21EX series) and planning
  6. 6. Treatment Planning Systems proficiency: Eclipse, BrachyVision, VariSeed, Vitesse
  7. 7. 4DTC acquisition
  8. 8. SBRT for pelvic sites (GYN)
  9. 9. HDR afterloader acceptance, commissioning and QA (Varian and Nucletron equipment),
  10. 10. LDR/HDR commissioning of TPS, LDR prostate, LDR T&O, LDR interstitial, LDR eye plaques, HDR gyn, endobronchial, interstitial;
  11. 11. LDR and HDR applicator commissioning and QA
  12. 12. Commissioned several in-vivo dosimetry systems: MOSFETS, OneDose
  13. 13. Hyperthermia superficial and deep heating BSD equipment commissioning and QA
  14. 14. Other: MIM, Velocity
  Clinical Experience (Leadership):
  
  2003-2010; 2015(temp): Lead physicist TBI/TSI team:
  1. Commissioned TBI/TSI
  2. Developed clinical procedures
  3. In-service for therapists
  4. Rotation supervision for MP Residency program: large field dosimetry
  5. Wrote physics section of multi institutional SCOT protocol and served as main QA site and physics consultant for the protocol
  6. Implemented paperless documentation for these procedures
  2003-present: Lead physicist on rotation basis of one of the linear accelerators
  1. Responsible for day-to-day correct function of the linac
  2. Performing QA after upgrades to hardware or software by manufacturer
  3. Check daily QA
  4. Perform monthly and annual QA and imaging QA
  5. Since 2006 trained MP students and residents on linac function and maintenance.
  2008-2017: Lead physicist Brachytherapy team
  1. Commissioned Varian (GMPiX) HDR afterloaders
  2. Commissioned and configured TPS: BrachyVision, Vitesse
  3. Implemented MR-based treatment planning for GYN HDR applications
  4. Commissioned HDR applicators: T&O (LDR and HDR), T&R, vaginal stump cylinders, Miami, Capri, endobronchial catheters, HDR needles for GYN and prostate applications, HAM applicators, COMS Eye Plaques
  5. Commissioned US-based, real time HDR for prostate patients
  6. Calibrations for HDR source, LDR seeds and sources
  7. Implemented TG129 for LDR Eye Plaque Program
  8. Developed clinical and QA procedures for all HDR applications; Co-developed clinical and QA procedures for most LDR applications (over 40 procedures)
  9. Accepted and commissioned BK Focus 500 US system
  10. Active member of team: planning, QA, delivery
  11. Implemented paperless documentation for these procedures
  12. Schedule all procedures coverage
  13. Evaluated brachytherapy program at Duke Cancer Center Macon Pond and make recommendations
  14. Rotation supervisor for MP Residency program: Brachytherapy
  15. Guided, supervised and reviewed residents clinical research projects
  16. Invited symposia organizer and chair for AAPM 2012, 2013, 2014, 2015(deferred to a colleague due to inability to attend), 2016, ABS 2016
  17. Adhoc consultant for Varian Medical Systems Brachytherapy division (2012-present)
  2009-2014: Lead physicist Sarcoma planning team; 2009-present: Lead physicist Gynecological Malignancies planning team
  1. Worked closely with dosimetry to develop simulation flows for the different type treatments
  2. Implemented IMRT and VMAT planning for GYN malignancies and sarcomas
  3. Actively involved in planning cases
  4. Trained dosimetrists on the team
  5. Check all IMRT/VMAT plans before presenting to physician
  6. Trained MP residents rotating in dosimetry
  7. Department morning talks on GYN Planning
  8. Guided, supervised and reviewed dosimetrists/residents clinical research projects

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Education, Training, & Certifications

Previous Appointments & Affiliations

Leadership & Clinical Positions at Duke

In the News

Awards & Honors

Subject Headings

Global Scholarship

Expertise

Selected Grants

Selected Publications

Academic Articles

Book Sections

Conference Papers

Recent Courses

Advising & Mentoring

Available to mentor:

Teaching Activities

Presentations & Appearances

Outreach & Engaged Scholarship

Service to the Profession

Service to Duke

Academic & Administrative Activities

Clinical Activities