Loretta Georgina Que
Professor of Medicine

My research interests focus on studying the role of nitric oxide and related enzymes in the pathogenesis of lung disease, specifically that caused by nitrosative/oxidative stress. Proposed studies are performed in cell culture and applied to animal models of disease, then examined in human disease where relevant. It is our hope that by better understanding the role of NO and reactive nitrogen species in mediating inflammation, and regulating cell signaling, that we will not only help to unravel the basic mechanisms of NO related lung disease, but also provide a rationale for targeted therapeutic use of NO.

Key words: nitrosative defense, lung injury, nitric oxide

Current Research Interests

     Obese asthma
     Airway inflammation and airway remodeling
Oxidative stress
Xenon MRI
COVID 19 related lung disease

Current Appointments & Affiliations

Contact Information

  • 279 Msrb1, Durham, NC 27710
  • Duke Box 2629, 203 Research Dr, Durham, NC 27710

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