Scholars@Duke
Rowena Joy Dolor

Rowena Joy Dolor

Professor of Medicine
Medicine, General Internal Medicine
Duke Box 104427, Durham, NC 27701
710 W. Main Street, 1st Floor, Durham, NC 27701

Selected Publications

Effect of Screening for Undiagnosed Atrial Fibrillation on Stroke Prevention.

Journal Article J Am Coll Cardiol · November 19, 2024 BACKGROUND: Atrial fibrillation (AF) often remains undiagnosed, and it independently raises the risk of ischemic stroke, which is largely reversible by oral anticoagulation. Although randomized trials using longer term screening approaches increase identif ... Full text Link to item Cite

Routine Hearing Screening for Older Adults in Primary Care: Insights of Patients and Clinic Personnel.

Journal Article Gerontologist · October 1, 2024 BACKGROUND AND OBJECTIVES: Hearing loss frequently goes undiagnosed and untreated, with serious sequelae. Hearing screening facilitates diagnosis and treatment but is not routinely conducted in primary care. This study addresses the attitudes and insights ... Full text Link to item Cite

Atrial Fibrillation Burden on a 14-Day ECG Monitor: Findings From the GUARD-AF Trial Screening Arm.

Journal Article JACC Clin Electrophysiol · September 1, 2024 BACKGROUND: The "burden" of atrial fibrillation (AF) detected by screening likely influences stroke risk, but the distribution of burden is not well described. OBJECTIVES: This study aims to determine the frequency of AF and the distribution of AF burden f ... Full text Link to item Cite

Feasibility of tracking invasive Escherichia coli disease among older adults in a community setting: A prospective observational study.

Journal Article Eur J Clin Microbiol Infect Dis · March 2024 PURPOSE: Invasive Escherichia coli disease (IED) encompasses a diverse range of sterile site infections. This study evaluated the feasibility of capturing IED among community-dwelling older adults to inform the implementation of a phase 3 efficacy trial of ... Full text Link to item Cite

Design of a Multicenter Randomized Controlled Trial comparing the effectiveness of shared decision making versus motivational interviewing plus cognitive behavioral therapy for voluntary opioid tapering: The INSPIRE study protocol.

Journal Article Contemp Clin Trials · February 2024 BACKGROUND: This paper describes the design and protocol of a pragmatic, randomized trial to evaluate the comparative effectiveness of shared decision making versus motivational interviewing plus cognitive behavioral therapy for chronic pain for the volunt ... Full text Open Access Link to item Cite

A Pragmatic Clinical Trial of Hearing Screening in Primary Care Clinics: Effect of Setting and Provider Encouragement.

Journal Article Ear Hear · January 2024 OBJECTIVES: The prevalence of hearing loss increases with age. Untreated hearing loss is associated with poorer communication abilities and negative health consequences, such as increased risk of dementia, increased odds of falling, and depression. Nonethe ... Full text Link to item Cite

"Click and mortar" opportunities for digitization and consumerism in trials.

Journal Article Contemp Clin Trials · September 2023 BACKGROUND: Digitization (using novel digital tools and strategies) and consumerism (taking a consumer-oriented approach) are increasingly commonplace in clinical trials, but the implications of these changes are not well described. METHODS: We assembled a ... Full text Link to item Cite

Models for Delivering Weight Management in Primary Care: Qualitative Results from the MOST Obesity Study.

Journal Article J Am Board Fam Med · August 9, 2023 BACKGROUND: Obesity is a leading cause of morbidity and mortality in the United States (US). Primary care medical practices can educate patients about the health effects of obesity and help patients with obesity lose and manage their weight. However, imple ... Full text Link to item Cite

Effect of intratrial mean 25(OH)D concentration on diabetes risk, by race and weight: an ancillary analysis in the D2d study.

Journal Article Am J Clin Nutr · July 2023 BACKGROUND: Higher serum 25-hydroxyvitamin D [25(OH)D] is associated with lower type 2 diabetes risk. 25(OH)D varies due to skin pigmentation and weight. OBJECTIVES: This analysis aims to determine whether the effect of vitamin D differs among people of co ... Full text Link to item Cite

Pragmatic evaluation of events and benefits of lipid lowering in older adults (PREVENTABLE): Trial design and rationale.

Journal Article J Am Geriatr Soc · June 2023 Whether initiation of statins could increase survival free of dementia and disability in adults aged ≥75 years is unknown. PREVENTABLE, a double-blind, placebo-controlled randomized pragmatic clinical trial, will compare high-intensity statin therapy (ator ... Full text Link to item Cite

Provider Interaction With an Electronic Health Record Notification to Identify Eligible Patients for a Cluster Randomized Trial of Advance Care Planning in Primary Care: Secondary Analysis.

Journal Article J Med Internet Res · May 12, 2023 BACKGROUND: Advance care planning (ACP) improves patient-provider communication and aligns care to patient values, preferences, and goals. Within a multisite Meta-network Learning and Research Center ACP study, one health system deployed an electronic heal ... Full text Open Access Link to item Cite

Opioid dose and pain effects of an online pain self-management program to augment usual care in adults with chronic pain: a multisite randomized clinical trial.

Journal Article Pain · April 1, 2023 Readily accessible nonpharmacological interventions that can assist in opioid dose reduction while managing pain is a priority for adults receiving long-term opioid therapy (LOT). Few large-scale evaluations of online pain self-management programs exist th ... Full text Link to item Cite

Effect of Thromboprophylaxis on Clinical Outcomes After COVID-19 Hospitalization.

Journal Article Ann Intern Med · April 2023 BACKGROUND: Patients hospitalized with COVID-19 have an increased incidence of thromboembolism. The role of extended thromboprophylaxis after hospital discharge is unclear. OBJECTIVE: To determine whether anticoagulation is superior to placebo in reducing ... Full text Link to item Cite

Discriminative Accuracy of the CAPTURE Tool for Identifying Chronic Obstructive Pulmonary Disease in US Primary Care Settings.

Journal Article JAMA · February 14, 2023 IMPORTANCE: Chronic obstructive pulmonary disease (COPD) is underdiagnosed in primary care. OBJECTIVE: To evaluate the operating characteristics of the CAPTURE (COPD Assessment in Primary Care To Identify Undiagnosed Respiratory Disease and Exacerbation Ri ... Full text Link to item Cite

Effect of Fluvoxamine vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19: A Randomized Clinical Trial.

Journal Article JAMA · January 24, 2023 IMPORTANCE: The effectiveness of fluvoxamine to shorten symptom duration or prevent hospitalization among outpatients with mild to moderate symptomatic COVID-19 is unclear. OBJECTIVE: To evaluate the efficacy of low-dose fluvoxamine (50 mg twice daily) for ... Full text Link to item Cite

Primary care provider uptake of intensive behavioral therapy for obesity in Medicare patients, 2013-2019.

Journal Article PLoS One · 2023 BACKGROUND: The delivery of Intensive Behavioral Therapy (IBT) for obesity by primary care providers (PCPs) has been covered by Medicare to support elderly individuals with obesity (BMI > 30 kg/m2) in managing their weight since 2011 for individual therapy ... Full text Link to item Cite

Effect of a Patient Decision Aid on Preferences for Colorectal Cancer Screening Among Older Adults: A Secondary Analysis of a Randomized Clinical Trial.

Journal Article JAMA Netw Open · December 1, 2022 IMPORTANCE: Guidelines recommend individualized decision-making for colorectal cancer (CRC) screening among adults aged 76 to 84 years, a process that includes a consideration of health state and patient preference. OBJECTIVE: To determine whether a target ... Full text Link to item Cite

Fluvoxamine for Outpatient Treatment of COVID-19: A Decentralized, Placebo-controlled, Randomized, Platform Clinical Trial.

Journal Article medRxiv · November 1, 2022 BACKGROUND: The effectiveness of fluvoxamine to shorten symptom duration or prevent hospitalization among outpatients in the US with mild to moderate symptomatic coronavirus disease 2019 (COVID-19) is unclear. DESIGN: ACTIV-6 is an ongoing, decentralized, ... Full text Link to item Cite

Assessing Quality in Advance Care Planning Documentation: A Survey of Current Methods.

Journal Article Am J Hosp Palliat Care · August 2022 BACKGROUND: High-quality advance care planning (ACP) documentation facilitates the communication of patients' wishes as they progress in their disease course and travel between health care settings. No consensus exists regarding evaluation of documentation ... Full text Link to item Cite

Safety and tolerability of high-dose daily vitamin D3 supplementation in the vitamin D and type 2 diabetes (D2d) study-a randomized trial in persons with prediabetes.

Journal Article Eur J Clin Nutr · August 2022 BACKGROUND/OBJECTIVES: Routine use of vitamin D supplements has increased substantially in the United States. However, the safety and tolerability of long-term use of high-dose vitamin D are not known. We assessed the safety and tolerability of high-dose, ... Full text Link to item Cite

A pragmatic clinical trial of hearing screening in primary care clinics: cost-effectiveness of hearing screening.

Journal Article Cost Eff Resour Alloc · June 25, 2022 BACKGROUND: Hearing loss is a high prevalence condition among older adults, is associated with higher-than-average risk for poor health outcomes and quality of life, and is a public health concern to individuals, families, communities, professionals, gover ... Full text Link to item Cite

Differences in Cardiovascular Risk, Coronary Artery Disease, and Cardiac Events Between Black and White Individuals Enrolled in the PROMISE Trial.

Journal Article JAMA Cardiol · March 1, 2022 IMPORTANCE: Race and ethnicity have been studied as risk factors in cardiovascular disease. How risk factors, epicardial coronary artery disease, and cardiac events differ between Black and White individuals undergoing noninvasive testing for coronary arte ... Full text Link to item Cite

Effects of Vitamin D Supplementation on Insulin Sensitivity and Secretion in Prediabetes.

Journal Article J Clin Endocrinol Metab · January 1, 2022 CONTEXT: Vitamin D regulates glucose homeostasis pathways, but effects of vitamin D supplementation on β-cell function remain unclear. OBJECTIVE: To investigate the effects of vitamin D3 supplementation on insulin sensitivity and β-cell function. METHODS: ... Full text Link to item Cite

Dissemination and implementation science resources, training, and scientific activities provided through CTSA programs nationally: Opportunities to advance D&I research and training capacity.

Journal Article J Clin Transl Sci · 2022 INTRODUCTION: Clinical and Translational Science Award (CTSA) Program hubs are well-positioned to advance dissemination and implementation (D&I) research and training capacity nationally, though little is known about what D&I research support and services ... Full text Link to item Cite

Integrating Patient-generated Digital Health Data into Electronic Health Records (EHRs) in Ambulatory Care Settings: EHR Vendor Survey and Interviews.

Journal Article AMIA Jt Summits Transl Sci Proc · 2022 Data traditionally collected in a clinic or hospital setting is now collected electronically in everyday environments from patients, known as patient-generated health data (PGHD). We conducted informal interviews and collected survey data from major ambula ... Link to item Cite

Cardiovascular risk and outcomes in symptomatic patients with suspected coronary artery disease and non coronary vascular disease: A report from the PROMISE trial.

Journal Article Am Heart J · December 2021 BACKGROUND: Non-coronary vascular disease (NCVD) is associated with adverse cardiovascular events. Little is known about physician risk assessment, prevalence of coronary artery disease (CAD), cardiac catheterization, and the performance of the atheroscler ... Full text Link to item Cite

A Survey of Primary Care Practices on Their Use of the Intensive Behavioral Therapy for Obese Medicare Patients.

Journal Article J Gen Intern Med · September 2021 OBJECTIVE: To fill the gap in knowledge on systematic differences between primary care practices (PCP) that do or do not provide intensive behavioral therapy (IBT) for obese Medicare patients. METHODS: A mixed modality survey (paper and online) of primary ... Full text Link to item Cite

Vitamin D Supplementation for Prevention of Cancer: The D2d Cancer Outcomes (D2dCA) Ancillary Study.

Journal Article J Clin Endocrinol Metab · August 18, 2021 CONTEXT: Observational studies suggest that low vitamin D status may be a risk factor for cancer. OBJECTIVE: In a population with prediabetes and overweight/obesity that is at higher risk of cancer than the general population, we sought to determine if vit ... Full text Link to item Cite

Effect of Vitamin D Supplementation on Kidney Function in Adults with Prediabetes: A Secondary Analysis of a Randomized Trial.

Journal Article Clin J Am Soc Nephrol · August 2021 BACKGROUND AND OBJECTIVES: Low serum 25-hydroxyvitamin D (25[OH]D) concentration has been associated with higher levels of proteinuria and lower levels of eGFR in observational studies. In the Vitamin D and Type 2 Diabetes (D2d) study, we investigated the ... Full text Link to item Cite

Options for Meaningful Engagement in Clinical Research for Busy Frontline Clinicians.

Journal Article J Gen Intern Med · July 2021 In order for health care innovations to be effective and actionable, they must align with the needs and practice patterns of those delivering care at the bedside. While research has started to incorporate the patient voice, it has yet to fully invest in th ... Full text Link to item Cite

Advance care planning billing practices and documentation quality for cancer patients requiring hospitalization.

Conference Journal of Clinical Oncology · May 20, 2021 e24000 Background: Advance Care Planning (ACP) is an important component of comprehensive cancer care, yet barriers exist to successful implementation. In 2016, Medicare introduced billing codes to provide reimbursement for ACP d ... Full text Cite

Using the Consolidated Framework for Implementation Research (CFIR) to evaluate implementation effectiveness of a facilitated approach to an asthma shared decision making intervention.

Journal Article J Asthma · April 2021 OBJECTIVE: To describe the evaluation of implementation effectiveness of an asthma shared decision making (SDM) intervention at the 10 individual facilitator-led primary care practices in the ADAPT-NC Study using the Consolidated Framework for Implementati ... Full text Link to item Cite

Design considerations for a remote randomized multi-site clinical trial evaluating an e-health self-management program for chronic pain patients receiving opioid therapy.

Journal Article Contemp Clin Trials · February 2021 Based on the adverse consequences and inadequate evidence of effectiveness for long-term opioid therapy (LOT), the CDC developed recommendations to decrease the use of LOT and morphine equivalent dose (MED) for patients receiving LOT. However, the majority ... Full text Link to item Cite

General Behavioral Engagement and Changes in Clinical and Cognitive Outcomes of Patients with Type 2 Diabetes Using the Time2Focus Mobile App for Diabetes Education: Pilot Evaluation.

Journal Article J Med Internet Res · January 20, 2021 BACKGROUND: Type 2 diabetes affects 30 million Americans, representing a significant cause of morbidity and mortality. Self-management support is an important component of chronic illness care and is a key pillar of the chronic care model. Face-to-face tea ... Full text Link to item Cite

Protocol Summary of the COPD Assessment in Primary Care To Identify Undiagnosed Respiratory Disease and Exacerbation Risk (CAPTURE) Validation in Primary Care Study.

Journal Article Chronic Obstr Pulm Dis · January 2021 Chronic obstructive pulmonary disease (COPD) often remains undiagnosed and untreated. To date, COPD screening/case finding has not been designed to identify clinically significant COPD, disease ready for therapies beyond smoking cessation. Herein, we descr ... Full text Link to item Cite

Economic outcomes of depression screening after acute coronary syndromes: The CODIACS-QoL randomized clinical trial.

Journal Article Gen Hosp Psychiatry · 2021 OBJECTIVE: To evaluate the cost-effectiveness of screening for depression in patients with acute coronary syndrome (ACS) and no history of depression. METHODS: Cost-effectiveness analysis of a randomized trial enrolling 1500 patients with ACS between 2013 ... Full text Link to item Cite

Integrating dissemination and implementation sciences within Clinical and Translational Science Award programs to advance translational research: Recommendations to national and local leaders.

Journal Article J Clin Transl Sci · 2021 The National Center for Advancing Translational Sciences (NCATS) has defined translation as the process of turning observations into interventions that are adopted, sustained, and improve health. Translation must attend to research and community systems an ... Full text Link to item Cite

BILLING PRACTICES FOR ADVANCE CARE PLANNING AT AN ACADEMIC INSTITUTION

Conference JOURNAL OF GENERAL INTERNAL MEDICINE · 2021 Cite

Comparative implementation-effectiveness of three strategies to perform hearing screening among older adults in primary care clinics: study design and protocol.

Journal Article BMC Geriatr · May 11, 2020 BACKGROUND: The burden of hearing loss among older adults could be mitigated with appropriate care. This study compares implementation of three hearing screening strategies in primary care, and examines the reliability and validity of patient self-assessme ... Full text Link to item Cite

A Community-based Assessment of Skin Care, Allergies, and Eczema (CASCADE): an atopic dermatitis primary prevention study using emollients-protocol for a randomized controlled trial.

Journal Article Trials · March 4, 2020 BACKGROUND: Atopic dermatitis (AD) is a common, chronic skin disorder often beginning in infancy. Skin barrier dysfunction early in life serves as a central event in the pathogenesis of AD. In infants at high risk of developing AD, preventative application ... Full text Link to item Cite

Implications of the Hemoglobin Glycation Index on the Diagnosis of Prediabetes and Diabetes.

Journal Article J Clin Endocrinol Metab · March 1, 2020 OBJECTIVE: Fasting plasma glucose (FPG), 2-hour plasma glucose (2hPG) from a 75-g oral glucose tolerance test (OGTT) and glycated hemoglobin (HbA1c) can lead to different results when diagnosing prediabetes and diabetes. The Hemoglobin Glycation Index (HGI ... Full text Link to item Cite

Increasing collaboration on substance use disorder research with primary care practices through the National Drug Abuse Treatment Clinical Trials Network.

Journal Article J Subst Abuse Treat · March 2020 BACKGROUND: The National Drug Abuse Treatment Clinical Trials Network (CTN) called for its national nodes to promote the translation of evidence-based interventions from substance use disorder (SUD) research into clinical practices. This collaborative demo ... Full text Link to item Cite

Effect of Depression Screening After Acute Coronary Syndromes on Quality of Life: The CODIACS-QoL Randomized Clinical Trial.

Journal Article JAMA Intern Med · January 1, 2020 IMPORTANCE: Patients with acute coronary syndrome (ACS) and elevated depressive symptoms are at increased risk for recurrent cardiovascular events and mortality, worse quality of life, and higher health care costs. These observational findings prompted mul ... Full text Link to item Cite

Research nurses as practice facilitators to disseminate an asthma shared decision making intervention.

Journal Article BMC Nurs · 2020 BACKGROUND: Practice facilitation is a method of introducing and sustaining organizational change. It involves the use of skilled healthcare professionals called practice facilitators (PFs) to help address the challenges associated with implementing eviden ... Full text Link to item Cite

The CAPTURE Study: Prevalence of Chronic Obstructive Pulmonary Disease in Primary Care Settings

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · 2020 Cite

High Quality Spirometry Can Be Performed at Diverse Primary Care Practice Based Research Network Sites

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · 2020 Cite

Disparities in Advance care planning (ACP): Has COVID-19 changed anything?

Conference JOURNAL OF THE AMERICAN GERIATRICS SOCIETY · 2020 Cite

General Behavioral Engagement and Changes in Clinical and Cognitive Outcomes of Patients with Type 2 Diabetes Using the Time2Focus Mobile App for Diabetes Education: Pilot Evaluation (Preprint)

Journal Article · December 18, 2019 BACKGROUNDType 2 diabetes affects 30 million Americans, representing a significant cause of morbidity and mortality. Self-management support is an important component of chronic illness c ... Full text Cite

Asthma dissemination around patient-centered treatments in North Carolina (ADAPT-NC): a cluster randomized control trial evaluating dissemination of an evidence-based shared decision-making intervention for asthma management.

Journal Article J Asthma · October 2019 Objective: To compare three dissemination approaches for implementing an asthma shared decision-making (SDM) intervention into primary care practices. Methods: We randomized thirty practices into three study arms: (1) a facilitator-led approach to implemen ... Full text Link to item Cite

Dissemination and implementation science activities across the Clinical Translational Science Award (CTSA) Consortium: Report from a survey of CTSA leaders.

Journal Article J Clin Transl Sci · September 25, 2019 INTRODUCTION: Dissemination and implementation (D&I) science is not a formal element of the Clinical Translational Science Award (CTSA) Program, and D&I science activities across the CTSA Consortium are largely unknown. METHODS: The CTSA Dissemination, Imp ... Full text Link to item Cite

Rationale, design, and baseline data for a multicenter randomized clinical trial comparing depression screening strategies after acute coronary syndrome: The comparison of depression identification after acute Coronary Syndromes-Quality of Life and Cost Outcomes (CODIACS-QOL) trial.

Journal Article Contemp Clin Trials · September 2019 BACKGROUND: Elevated depressive symptoms among survivors of acute coronary syndromes (ACS) confer recurrent cardiovascular events and mortality, worse quality of life, and higher healthcare costs. While multiple scientific groups advise routine depression ... Full text Link to item Cite

Reducing Disparities in the Quality of Palliative Care for Older African Americans through Improved Advance Care Planning: Study Design and Protocol.

Journal Article J Palliat Med · September 2019 Advance care planning (ACP) improves end-of-life care for patients and their caregivers. However, only one-third of adults have participated in ACP and rates are substantially lower among African Americans than among whites. Importantly, ACP improves many ... Full text Link to item Cite

Vitamin D Supplementation and Prevention of Type 2 Diabetes.

Journal Article N Engl J Med · August 8, 2019 BACKGROUND: Observational studies support an association between a low blood 25-hydroxyvitamin D level and the risk of type 2 diabetes. However, whether vitamin D supplementation lowers the risk of diabetes is unknown. METHODS: We randomly assigned adults ... Full text Link to item Cite

Situating dissemination and implementation sciences within and across the translational research spectrum.

Journal Article J Clin Transl Sci · July 29, 2019 The efficient and effective movement of research into practice is acknowledged as crucial to improving population health and assuring return on investment in healthcare research. The National Center for Advancing Translational Science which sponsors Clinic ... Full text Link to item Cite

Assessing Key Stakeholders' Knowledge, Needs, and Preferences for Head and Neck Cancer Survivorship Care Plans.

Journal Article J Cancer Educ · June 2019 Cancer survivorship care plans (SCPs) are endorsed to support quality care for cancer survivors, but uptake is slow. We assessed knowledge, needs, and preferences for SCP content and delivery from a wide variety of stakeholders. We focused SCP content for ... Full text Open Access Link to item Cite

Vitamin D supplementation for prevention of cancer: The D2d cancer outcomes (D2dCA) study.

Journal Article Contemp Clin Trials · June 2019 Evidence on biological plausibility from mechanistic studies and data from observational studies suggest that vitamin D may be linked to risk of several types of cancer. However, evidence from clinical trials evaluating the effect of vitamin D supplementat ... Full text Link to item Cite

Sex differences in management and outcomes of patients with stable symptoms suggestive of coronary artery disease: Insights from the PROMISE trial.

Journal Article Am Heart J · February 2019 BACKGROUND: Although sex differences exist in the management of acute coronary syndromes, less is known about the management and outcomes of women and men with suspected coronary artery disease being evaluated with noninvasive testing (NIT). METHODS: We in ... Full text Link to item Cite

The Burden of Childhood Atopic Dermatitis in the Primary Care Setting: A Report from the Meta-LARC Consortium.

Journal Article J Am Board Fam Med · 2019 BACKGROUND: Little is known about the burden of atopic dermatitis (AD) encountered in US primary care practices and the frequency and type of skin care practices routinely used in children. OBJECTIVE: To estimate the prevalence of AD in children 0 to 5 yea ... Full text Link to item Cite

A Multilevel Approach to Stakeholder Engagement in the Formulation of a Clinical Data Research Network.

Journal Article Med Care · October 2018 OBJECTIVES: To ensure meaningful engagement of stakeholders (patients, clinicians, and communities) in developing the Mid-South Clinical Data Research Network (MS-CDRN), we implemented a comprehensive, multilevel approach: (1) identify barriers to involvin ... Full text Link to item Cite

Clinicians' perspectives on and interest in participating in a clinical data research network across the Southeastern United States.

Journal Article BMC Health Serv Res · July 20, 2018 BACKGROUND: Partnerships between clinicians and researchers could increase the generalizability of research findings and increase uptake of research results across populations. Yet engaging clinicians in research is challenging. Clinical Data Research Netw ... Full text Link to item Cite

A Decision Aid to Promote Appropriate Colorectal Cancer Screening among Older Adults: A Randomized Controlled Trial.

Journal Article Med Decis Making · July 2018 BACKGROUND: Concerns have been raised about both over- and underutilization of colorectal cancer (CRC) screening in older patients and the need to align screening behavior with likelihood of net benefit. OBJECTIVE: The purpose of this study was to test a n ... Full text Link to item Cite

OPPORTUNITIES FOR OBESITY MANAGEMENT IN US PRIMARY CARE PRACTICES

Conference ANNALS OF BEHAVIORAL MEDICINE · April 1, 2018 Link to item Cite

Assessing key stakeholders' knowledge, needs, and preferences for cancer survivorship care plans.

Conference Journal of Clinical Oncology · March 1, 2018 30 Background: Survivorship care plans (SCPs) are individualized documents that summarize cancer treatment received and provide guidelines for monitoring and maintaining survivors’ health. While SCPs are intended to facilitate ca ... Full text Cite

Exploring factors that might influence primary-care provider discussion of and recommendation for prostate and colon cancer screening.

Journal Article Int J Gen Med · 2018 BACKGROUND: Primary-care providers may contribute to the use of low-value cancer screening. OBJECTIVE: We sought to examine circumstances under which primary-care providers would discuss and recommend two types of cancer screening services across a spectru ... Full text Link to item Cite

A feasibility study to develop and test a Spanish patient and provider intervention for managing osteoarthritis in Hispanic/Latino adults (PRIMO-Latino).

Journal Article Pilot Feasibility Stud · 2018 BACKGROUND: Arthritis affects approximately 50 million adults in the USA. Hispanics/Latinos have a higher prevalence of arthritis-attributed activity limitations primarily related to osteoarthritis (OA). Hispanic/Latinos are less likely to receive hip repl ... Full text Open Access Link to item Cite

Design of a randomized clinical trial of a colorectal cancer screening decision aid to promote appropriate screening in community-dwelling older adults.

Journal Article Clin Trials · December 2017 BACKGROUND: Appropriate colorectal cancer screening in older adults should be aligned with the likelihood of net benefit. In general, patient decision aids improve knowledge and values clarity, but in older adults, they may also help patients identify thei ... Full text Link to item Cite

Quantifying sociodemographic and income disparities in medical therapy and lifestyle among symptomatic patients with suspected coronary artery disease: a cross-sectional study in North America.

Journal Article BMJ Open · September 29, 2017 OBJECTIVES: To evaluate potential gaps in preventive medical therapy and healthy lifestyle practices among symptomatic patients with suspected coronary artery disease (CAD) seeing primary care physicians and cardiologists and how gaps vary by sociodemograp ... Full text Link to item Cite

195 The burden of childhood atopic dermatitis in U.S. primary care settings

Conference Journal of Investigative Dermatology · May 2017 Full text Cite

Integrative health care services utilization as a function of body mass index: A BraveNet practice-based research network study

Journal Article Advances in Integrative Medicine · April 1, 2017 Background Obesity is a significant public health issue with no consensus regarding optimal medical management. Integrative medicine (IM) may help to fill this gap. Objectives (1) To characterize the sociodemographics, psychosocial functioning, health beha ... Full text Cite

Patient, Provider, and Combined Interventions for Managing Osteoarthritis in Primary Care: A Cluster Randomized Trial.

Journal Article Ann Intern Med · March 21, 2017 BACKGROUND: A single-site study showed that a combined patient and provider intervention improved outcomes for patients with knee osteoarthritis, but it did not assess separate effects of the interventions. OBJECTIVE: To examine whether patient-based, prov ... Full text Open Access Link to item Cite

Perceived Stress in Patients with Common Gastrointestinal Disorders: Associations with Quality of Life, Symptoms and Disease Management.

Journal Article Explore (NY) · 2017 OBJECTIVE AND METHODS: Research supports relationships between stress and gastrointestinal (GI) symptoms and disorders. This pilot study assesses relationships between perceived stress, quality of life (QOL), and self-reported pain ratings as an indicator ... Full text Link to item Cite

Peripheral Artery Disease and Cardiovascular Risk in Patients Presenting With Chest Pain: Insights From the PROMISE Trial

Conference · 2017 Introduction: Peripheral artery disease (PAD) is considered a coronary risk equivalent and is associated with increased risk of adverse cardiovascular (CV) events. Yet, as compared to other high-risk groups, little is known about the relative risk of adver ... Cite

Raising Awareness ... Starting the Conversation

Conference MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY · December 1, 2016 Link to item Cite

Changes in Medical Therapy and Lifestyle After Anatomical or Functional Testing for Coronary Artery Disease.

Journal Article J Am Heart Assoc · October 12, 2016 BACKGROUND: Diagnostic testing in the care of patients newly presenting with symptoms suggestive of coronary artery disease may influence risk factor management, independent of test type or test results. However, little is known about changes in medication ... Full text Open Access Link to item Cite

Teaching primary care physicians the 5 A's for discussing weight with overweight and obese adolescents.

Journal Article Patient Educ Couns · October 2016 OBJECTIVE: We developed an online intervention to teach physicians both MI (addressed in outcomes paper) and the 5 A's (Ask, Advise, Assess, Assist, and Arrange) when discussing weight with overweight/obese adolescents. METHODS: We audio recorded 527 encou ... Full text Link to item Cite

Economic Outcomes With Anatomical Versus Functional Diagnostic Testing for Coronary Artery Disease.

Journal Article Ann Intern Med · July 19, 2016 BACKGROUND: PROMISE (PROspective Multicenter Imaging Study for Evaluation of Chest Pain) found that initial use of at least 64-slice multidetector computed tomography angiography (CTA) versus functional diagnostic testing strategies did not improve clinica ... Full text Open Access Link to item Cite

Teaching Physicians Motivational Interviewing for Discussing Weight With Overweight Adolescents.

Journal Article J Adolesc Health · July 2016 PURPOSE: We tested whether an online intervention combined with a patient feedback report improved physicians' use of motivational interviewing (MI) techniques when discussing weight with overweight and obese adolescents. METHODS: We randomized 46 pediatri ... Full text Link to item Cite

Sex Differences in Functional and CT Angiography Testing in Patients With Suspected Coronary Artery Disease.

Journal Article J Am Coll Cardiol · June 7, 2016 BACKGROUND: Although risk stratification is an important goal of cardiac noninvasive tests (NITs), few contemporary data exist on the prognostic value of different NITs according to patient sex. OBJECTIVES: The goal of this study was to compare the results ... Full text Link to item Cite

Sex Differences in Demographics, Risk Factors, Presentation, and Noninvasive Testing in Stable Outpatients With Suspected Coronary Artery Disease: Insights From the PROMISE Trial.

Journal Article JACC Cardiovasc Imaging · April 2016 OBJECTIVES: The aim of this study was to determine whether presentation, risk assessment, testing choices, and results differ by sex in stable symptomatic outpatients with suspected coronary artery disease (CAD). BACKGROUND: Although established CAD presen ... Full text Link to item Cite

Patients Receiving Integrative Medicine Effectiveness Registry (PRIMIER) of the BraveNet practice-based research network: study protocol.

Journal Article BMC Complement Altern Med · February 4, 2016 BACKGROUND: Integrative medicine (IM) provides patient-centered care and addresses the full range of physical, emotional, mental, social, spiritual, and environmental influences that affect a person's health. IM is a "whole systems" approach that employs m ... Full text Link to item Cite

A Comparative Effectiveness Trial of Alternate Formats for Presenting Benefits and Harms Information for Low-Value Screening Services: A Randomized Clinical Trial.

Journal Article JAMA Intern Med · January 2016 IMPORTANCE: Healthcare overuse, the delivery of low-value services, is increasingly recognized as a critical problem. However, little is known about the comparative effectiveness of alternate formats for presenting benefits and harms information to patient ... Full text Link to item Cite

Practice-based Research Network Research Good Practices (PRGPs): Summary of Recommendations.

Journal Article Clin Transl Sci · December 2015 INTRODUCTION: Practice-based research networks (PBRNs) conduct research in community settings, which poses quality control challenges to the integrity of research, such as study implementation and data collection. A foundation for improving research proces ... Full text Link to item Cite

Team Science Approach to Developing Consensus on Research Good Practices for Practice-Based Research Networks: A Case Study.

Journal Article Clin Transl Sci · December 2015 Using peer learning strategies, seven experienced PBRNs working in collaborative teams articulated procedures for PBRN Research Good Practices (PRGPs). The PRGPs is a PBRN-specific resource to facilitate PBRN management and staff training, to promote adher ... Full text Link to item Cite

Studying physician-adolescent patient communication in community-based practices: recruitment challenges and solutions.

Journal Article Int J Adolesc Med Health · November 13, 2015 BACKGROUND: Practice-based studies are needed to assess how physicians communicate health messages about weight to overweight/obese adolescent patients, but successful recruitment to such studies is challenging. This paper describes challenges, solutions, ... Full text Link to item Cite

Changes in Medical Therapy and Lifestyle After Anatomical Versus Functional Testing for Coronary Artery Disease: The PROMISE Trial (PROspective Multicenter Imaging Study for Evaluation of Chest Pain)

Conference · November 10, 2015 Introduction: Diagnostic testing may represent a “teachable moment” for patients newly presenting with symptoms suggestive of CAD and requiring further evaluation, and may influence risk factor management, independent of test results. However, little is kn ... Open Access Link to item Cite

Adult Patients' Perspectives on the Benefits and Harms of Overused Screening Tests: a Qualitative Study.

Journal Article J Gen Intern Med · November 2015 BACKGROUND: In recent years, there has been a growing interest in reducing the overuse of healthcare services. However, little is known about how patients conceptualize the benefits and harms of overused screening tests or how patients make decisions regar ... Full text Link to item Cite

Individual Proton Pump Inhibitors and Outcomes in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy: A Systematic Review.

Journal Article J Am Heart Assoc · October 29, 2015 BACKGROUND: Observational studies evaluating the possible interaction between proton pump inhibitors (PPIs) and clopidogrel have shown mixed results. We conducted a systematic review comparing the safety of individual PPIs in patients with coronary artery ... Full text Open Access Link to item Cite

DIRECT PRIMARY CARE (DPC) SUMMIT DRAWS HUNDREDS OF ENTHUSIASTIC FAMILY PHYSICIANS

Journal Article The Annals of Family Medicine · September 1, 2015 Full text Cite

Letter response.

Journal Article Am Heart J · August 2015 Full text Link to item Cite

The impact of frequency of patient self-testing of prothrombin time on time in target range within VA Cooperative Study #481: The Home INR Study (THINRS), a randomized, controlled trial.

Journal Article J Thromb Thrombolysis · July 2015 Anticoagulation (AC) is effective in reducing thromboembolic events for individuals with atrial fibrillation (AF) or mechanical heart valve (MHV), but maintaining patients in target range for international normalized ratio (INR) can be difficult. Evidence ... Full text Open Access Link to item Cite

Disclosure of Sexual Intercourse by Teenagers: Agreement Between Telephone Survey Responses and Annual Visit Disclosures.

Journal Article Clin Pediatr (Phila) · June 2015 BACKGROUND: Physicians can help guide teenagers in their emerging sexuality; however, teens rarely inform physicians about their sexual activity. METHODS: We audio-recorded annual visits between 365 teenagers and 49 physicians. Before the recorded visit, t ... Full text Link to item Cite

Supervised vs unsupervised exercise for intermittent claudication: A systematic review and meta-analysis.

Journal Article Am Heart J · June 2015 BACKGROUND: Supervised exercise (SE) is widely accepted as an effective therapy for intermittent claudication (IC), but its use is limited by cost. Unsupervised exercise (UE) represents a less costly alternative. We assessed the comparative effectiveness o ... Full text Link to item Cite

Comparative Effectiveness of Medical Therapy, Supervised Exercise, and Revascularization for Patients With Intermittent Claudication: A Network Meta-analysis.

Journal Article Clin Cardiol · June 2015 BACKGROUND: There are limited data on the comparative effectiveness of medical therapy, supervised exercise, and revascularization to improve walking and quality of life in patients with intermittent claudication (IC). HYPOTHESIS: Supervised exercise and r ... Full text Link to item Cite

Nurse-led behavioral management of diabetes and hypertension in community practices: a randomized trial.

Journal Article J Gen Intern Med · May 2015 BACKGROUND: Several trials have demonstrated the efficacy of nurse telephone case management for diabetes (DM) and hypertension (HTN) in academic or vertically integrated systems. Little is known about the real-world potency of these interventions. OBJECTI ... Full text Open Access Link to item Cite

Antibody responses among adolescent females receiving the quadrivalent HPV vaccine series corresponding to standard or non-standard dosing intervals.

Journal Article Vaccine · April 15, 2015 Quadrivalent human papillomavirus vaccine (HPV4) is recommended as a 3-dose series administered at 0, 1-2, and 6 months. However, this dosing schedule is often not followed leading to longer dosing intervals. We conducted a prospective study to assess anti ... Full text Link to item Cite

Outcomes of anatomical versus functional testing for coronary artery disease.

Journal Article N Engl J Med · April 2, 2015 BACKGROUND: Many patients have symptoms suggestive of coronary artery disease (CAD) and are often evaluated with the use of diagnostic testing, although there are limited data from randomized trials to guide care. METHODS: We randomly assigned 10,003 sympt ... Full text Link to item Cite

Pain in adolescent girls receiving human papillomavirus vaccine with concomitantly administered vaccines.

Journal Article Pediatr Infect Dis J · February 2015 Using the Faces Pain Scale - Revised, we assessed injection site pain 10 minutes after vaccination in young females randomized to receive either quadrivalent human papillomavirus vaccine (HPV4) before or after concomitantly administered vaccines. Although ... Full text Link to item Cite

Conflicting results between randomized trials and observational studies on the impact of proton pump inhibitors on cardiovascular events when coadministered with dual antiplatelet therapy: systematic review.

Journal Article Circ Cardiovasc Qual Outcomes · January 2015 BACKGROUND: Discordant results have been reported on the effects of concomitant use of proton pump inhibitors (PPIs) and dual antiplatelet therapy (DAPT) for cardiovascular outcomes. We conducted a systematic review comparing the effectiveness and safety o ... Full text Link to item Cite

Integrative Medicine Patients Have High Stress, Pain, and Psychological Symptoms.

Journal Article Explore (NY) · 2015 CONTEXT: Integrative medicine (IM) is a rapidly growing field whose providers report clinical success in treating significant stress, chronic pain, and depressive and anxiety symptoms. While IM therapies have demonstrated efficacy for numerous medical cond ... Full text Link to item Cite

Clinic variation in recruitment metrics, patient characteristics and treatment use in a randomized clinical trial of osteoarthritis management.

Journal Article BMC Musculoskelet Disord · December 6, 2014 BACKGROUND: The Patient and PRovider Interventions for Managing Osteoarthritis (OA) in Primary Care (PRIMO) study is one of the first health services trials targeting OA in a multi-site, primary care network. This multi-site approach is important for asses ... Full text Open Access Link to item Cite

Impact of body mass index on immunogenicity of pandemic H1N1 vaccine in children and adults.

Journal Article J Infect Dis · October 15, 2014 Obesity emerged as a risk factor for morbidity and mortality related to 2009 pandemic influenza A (H1N1) infection. However, few studies examine the immune responses to H1N1 vaccine among children and adults of various body mass indices (BMI). Pooling data ... Full text Link to item Cite

Immunogenicity of avian influenza A/Anhui/01/2005(H5N1) vaccine with MF59 adjuvant: a randomized clinical trial.

Journal Article JAMA · October 8, 2014 IMPORTANCE: The need to respond quickly to potential influenza pandemics is important. Immunologic priming (initial presentation of an antigen to allow antibody responses on revaccination) with vaccine directed toward an older avian influenza H5 strain mig ... Full text Link to item Cite

Dual antiplatelet therapy with or without oral anticoagulation in the postdischarge management of acute coronary syndrome patients with an indication for long term anticoagulation: a systematic review.

Journal Article J Thromb Thrombolysis · October 2014 Currently, there is a lack of consensus among guidelines for the postdischarge treatment of patients presenting with acute coronary syndrome (ACS) who have a long-term indication for anticoagulation. We conducted a systematic review comparing the safety an ... Full text Link to item Cite

Characteristics of cancer patients presenting to an integrative medicine practice-based research network.

Journal Article Integr Cancer Ther · September 2014 OBJECTIVE: To assess psychosocial characteristics, symptoms and reasons for seeking integrative medicine (IM) care in cancer patients presenting to IM clinical practices. STUDY DESIGN AND METHODS: A survey of 3940 patients was conducted at 8 IM sites. Pati ... Full text Link to item Cite

Weight's up? Predictors of weight-related communication during primary care visits with overweight adolescents.

Journal Article Patient Educ Couns · September 2014 OBJECTIVE: Physicians' use of Motivational Interviewing (MI) techniques when discussing weight with adolescent patients is unknown. METHODS: We coded audio-recorded encounters between 49 primary care physicians and 180 overweight adolescent patients. Durin ... Full text Link to item Cite

Clinical and immune responses to inactivated influenza A(H1N1)pdm09 vaccine in children.

Journal Article Pediatr Infect Dis J · August 2014 BACKGROUND: As the influenza A H1N1 pandemic emerged in 2009, children were found to experience high morbidity and mortality and were prioritized for vaccination. This multicenter, randomized, double-blind, age-stratified trial assessed the safety and immu ... Full text Link to item Cite

PROspective Multicenter Imaging Study for Evaluation of chest pain: rationale and design of the PROMISE trial.

Journal Article Am Heart J · June 2014 BACKGROUND: Suspected coronary artery disease (CAD) is one of the most common, potentially life-threatening diagnostic problems clinicians encounter. However, no large outcome-based randomized trials have been performed to guide the selection of diagnostic ... Full text Link to item Cite

Comparative effectiveness and safety of drug therapy for pulmonary arterial hypertension: a systematic review and meta-analysis.

Journal Article Chest · May 2014 BACKGROUND: Current treatments for pulmonary arterial hypertension (PAH) have been shown to improve dyspnea, 6-min walk distance (6MWD), and pulmonary hemodynamics, but few studies were designed to compare treatment regimens or assess the impact of treatme ... Full text Link to item Cite

A national strategy to develop pragmatic clinical trials infrastructure.

Journal Article Clin Transl Sci · April 2014 An important challenge in comparative effectiveness research is the lack of infrastructure to support pragmatic clinical trials, which compare interventions in usual practice settings and subjects. These trials present challenges that differ from those of ... Full text Link to item Cite

Comparative effectiveness of endovascular and surgical revascularization for patients with peripheral artery disease and critical limb ischemia: systematic review of revascularization in critical limb ischemia.

Journal Article Am Heart J · April 2014 BACKGROUND: For patients with critical limb ischemia (CLI), the optimal treatment to enhance limb preservation, prevent death, and improve functional status is unknown. We performed a systematic review and meta-analysis to assess the comparative effectiven ... Full text Link to item Cite

Sexuality talk during adolescent health maintenance visits.

Journal Article JAMA Pediatr · February 2014 IMPORTANCE: Physicians may be important sources of sexuality information and preventive services, and one-on-one confidential time during health maintenance visits is recommended to allow discussions of sexual development, behavior, and risk reduction. How ... Full text Link to item Cite

Clinical practice guideline: acute otitis externa.

Journal Article Otolaryngol Head Neck Surg · February 2014 OBJECTIVE: This clinical practice guideline is an update and replacement for an earlier guideline published in 2006 by the American Academy of Otolaryngology-Head and Neck Surgery Foundation. This update provides evidence-based recommendations to manage ac ... Full text Link to item Cite

Accuracy and congruence of patient and physician weight-related discussions: from project CHAT (Communicating Health: Analyzing Talk).

Journal Article J Am Board Fam Med · 2014 OBJECTIVE: Primary care providers should counsel overweight patients to lose weight. Rates of self-reported, weight-related counseling vary, perhaps because of self-report bias. We assessed the accuracy and congruence of weight-related discussions among pa ... Full text Link to item Cite

Guidance for researchers developing and conducting clinical trials in practice-based research networks (PBRNs).

Journal Article J Am Board Fam Med · 2014 BACKGROUND: There is increased interest nationally in multicenter clinical trials to answer questions about clinical effectiveness, comparative effectiveness, and safety in real-world community settings. Primary care practice-based research networks (PBRNs ... Full text Link to item Cite

Teen CHAT: Development and utilization of a web-based intervention to improve physician communication with adolescents about healthy weight.

Journal Article Patient Educ Couns · December 2013 OBJECTIVE: To describe the theoretical basis, use, and satisfaction with Teen CHAT, an online educational intervention designed to improve physician-adolescent communication about healthy weight. METHODS: Routine health maintenance encounters between pedia ... Full text Link to item Cite

The influence of a physician and patient intervention program on dietary intake.

Journal Article J Acad Nutr Diet · November 2013 BACKGROUND: Efficient dietary interventions for patients with hypertension in clinical settings are needed. OBJECTIVE: To assess the separate and combined influence of a physician intervention (MD-I) and a patient intervention (PT-I) on dietary intakes of ... Full text Link to item Cite

Tailored Case Management for Diabetes and Hypertension (TEACH-DM) in a community population: study design and baseline sample characteristics.

Journal Article Contemp Clin Trials · September 2013 BACKGROUND: Despite recognition of the benefits associated with well-controlled diabetes and hypertension, control remains suboptimal. Effective interventions for these conditions have been studied within academic settings, but interventions targeting both ... Full text Open Access Link to item Cite

The BraveNet prospective observational study on integrative medicine treatment approaches for pain.

Journal Article BMC Complement Altern Med · June 24, 2013 BACKGROUND: Chronic pain affects nearly 116 million American adults at an estimated cost of up to $635 billion annually and is the No. 1 condition for which patients seek care at integrative medicine clinics. In our Study on Integrative Medicine Treatment ... Full text Link to item Cite

The patient centered medical home. A systematic review.

Journal Article Ann Intern Med · February 5, 2013 BACKGROUND: The patient-centered medical home (PCMH) describes mechanisms for organizing primary care to provide high quality care across the full range of individuals' health care needs.It is being widely implemented by provider organizations and third pa ... Full text Link to item Cite

Can physicians accurately predict which patients will lose weight, improve nutrition and increase physical activity?

Journal Article Fam Pract · October 2012 BACKGROUND: Physician counselling may help patients increase physical activity, improve nutrition and lose weight. However, physicians have low outcome expectations that patients will change. The aims are to describe the accuracy of physicians' outcome exp ... Full text Link to item Cite

Transitional care after hospitalization for acute stroke or myocardial infarction: a systematic review.

Journal Article Ann Intern Med · September 18, 2012 BACKGROUND: Transitional care is a time-limited service to prevent discontinuous care and adverse outcomes, including rehospitalization. PURPOSE: To describe transitional care interventions and evidence of benefit or harm in patients hospitalized for acute ... Full text Link to item Cite

Closing the quality gap: revisiting the state of the science (vol. 2: the patient-centered medical home).

Journal Article Evid Rep Technol Assess (Full Rep) · July 2012 OBJECTIVES: As part of the Closing the Quality Gap: Revisiting the State of the Science series of the Agency for Healthcare Research and Quality (AHRQ), this systematic review sought to identify completed and ongoing evaluations of the comprehensive patien ... Link to item Cite

THE PATIENT-CENTERED MEDICAL HOME, A SYSTEMATIC REVIEW

Journal Article JOURNAL OF GENERAL INTERNAL MEDICINE · July 1, 2012 Link to item Cite

Patient safety-focused medication therapy management: challenges affecting future implementation.

Journal Article Am J Manag Care · July 1, 2012 OBJECTIVES/BACKGROUND: Lessons learned from the implementation of a pharmacist-delivered medication therapy management (MTM) intervention in primary care (PC) can inform future MTM studies and be adopted into real-world clinical settings. We sought to desc ... Link to item Cite

Updated report on comparative effectiveness of ACE inhibitors, ARBs, and direct renin inhibitors for patients with essential hypertension: much more data, little new information.

Journal Article J Gen Intern Med · June 2012 OBJECTIVES: A 2007 systematic review compared angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) in patients with hypertension. Direct renin inhibitors (DRIs) have since been introduced, and significant new research ... Full text Link to item Cite

Patient and provider interventions for managing osteoarthritis in primary care: protocols for two randomized controlled trials.

Journal Article BMC Musculoskelet Disord · April 24, 2012 BACKGROUND: Osteoarthritis (OA) of the hip and knee are among the most common chronic conditions, resulting in substantial pain and functional limitations. Adequate management of OA requires a combination of medical and behavioral strategies. However, some ... Full text Open Access Link to item Cite

The influence of physician communication style on overweight patients' perceptions of length of encounter and physician being rushed.

Journal Article Fam Med · March 2012 BACKGROUND AND OBJECTIVES: Little is known about how patients and physicians perceive time and the extent to which they perceive the physician being rushed during encounters. One aim of this paper is to examine whether patient and physician characteristics ... Link to item Cite

The MURDOCK Study: a long-term initiative for disease reclassification through advanced biomarker discovery and integration with electronic health records.

Journal Article Am J Transl Res · 2012 BACKGROUND: Facing critically low return per dollar invested on clinical research and clinical care, the American biomedical enterprise is in need of a significant transformation. A confluence of high-throughput "omic" technologies and increasing adoption ... Link to item Cite

Patients seek integrative medicine for preventive approach to optimize health.

Journal Article Explore (NY) · 2012 CONTEXT: Despite the tremendous growth of integrative medicine (IM) in clinical settings, IM has not been well characterized in the medical literature. OBJECTIVE: To describe characteristics and motivation of patients seeking care at an IM clinic. DESIGN, ... Full text Link to item Cite

The Measurement to Understand Reclassification of Disease of Cabarrus/Kannapolis (MURDOCK) Study Community Registry and Biorepository.

Journal Article Am J Transl Res · 2012 Current understanding of chronic diseases is based on crude clinical characterization, imaging studies, and laboratory testing that has evolved over decades. The Measurement to Understand Reclassification of Disease of Cabarrus/Kannapolis (MURDOCK) Study i ... Link to item Cite

Safety-focused medication therapy management: a randomized controlled trial.

Journal Article J Am Pharm Assoc (2003) · 2012 OBJECTIVE: To evaluate the effect of a medication therapy management (MTM) intervention on adverse drug events (ADEs), health care visits, and drug-related problems (DRPs). DESIGN: Randomized, controlled, clinical trial. SETTING: Academic medical center co ... Full text Link to item Cite

Effects of counseling techniques on patients' weight-related attitudes and behaviors in a primary care clinic.

Journal Article Patient Educ Couns · December 2011 OBJECTIVE: Examine primary care physicians' use of counseling techniques when treating overweight and obese patients and the association with mediators of behavior change as well as change in nutrition, exercise, and weight loss attempts. METHODS: We audio ... Full text Link to item Cite

Predictors of weight loss communication in primary care encounters.

Journal Article Patient Educ Couns · December 2011 OBJECTIVE: Evidence suggests that physicians' use of motivational interviewing (MI) techniques helps patients lose weight. We assessed patient, physician, relationship, and systems predictors of length of weight-loss discussions and whether physicians' use ... Full text Link to item Cite

Transition of care for acute stroke and myocardial infarction patients: from hospitalization to rehabilitation, recovery, and secondary prevention.

Journal Article Evid Rep Technol Assess (Full Rep) · October 2011 OBJECTIVES: To review the available published literature to assess whether evidence supports a beneficial role for coordinated transition of care services for the postacute care of patients hospitalized with first or recurrent stroke or myocardial infarcti ... Link to item Cite

Partnership-driven Resources to Improve and Enhance Research (PRIMER): a survey of community-engaged researchers and creation of an online toolkit.

Journal Article Clin Transl Sci · August 2011 OBJECTIVE: This project aimed to develop an open-access website providing adaptable resources to facilitate best practices for multisite research from initiation to closeout. methods: A web-based assessment was sent to the leadership of the Clinical and Tr ... Full text Link to item Cite

Streamlining research by using existing tools.

Journal Article Clin Transl Sci · August 2011 Over the past two decades, the health research enterprise has matured rapidly, and many recognize an urgent need to translate pertinent research results into practice, to help improve the quality, accessibility, and affordability of US healthcare. Streamli ... Full text Link to item Cite

Management of skin abscesses by primary care pediatricians.

Journal Article Clin Pediatr (Phila) · June 2011 BACKGROUND: Staphylococcus aureus is a common cause of skin abscesses. OBJECTIVE: To evaluate primary care pediatricians' management of skin abscesses. METHODS: A national mail survey of a random sample of 385 general pediatricians conducted from April to ... Full text Link to item Cite

Weight-loss talks: what works (and what doesn't).

Journal Article J Fam Pract · April 2011 BACKGROUND: In primary care encounters, it is unknown whether physician advice on weight-related matters leads to patient weight loss. To examine this issue, we analyzed physician weight loss advice and measured corresponding changes in patients' dietary i ... Link to item Cite

Do the five A's work when physicians counsel about weight loss?

Journal Article Fam Med · March 2011 BACKGROUND AND OBJECTIVES: More than two thirds of Americans are overweight or obese. Physician counseling may help patients lose weight; however, physicians perceive these discussions as somewhat futile and time-consuming. An effective and efficient tool ... Link to item Cite

Physician characteristics as predictors of blood pressure control in patients enrolled in the hypertension improvement project (HIP).

Journal Article J Clin Hypertens (Greenwich) · February 2011 The authors sought to examine the relationship between physician characteristics and patient blood pressure (BP) in participants enrolled in the Hypertension Improvement Project (HIP). In this cross-sectional study using baseline data of HIP participants, ... Full text Link to item Cite

Physician empathy and listening: associations with patient satisfaction and autonomy.

Journal Article J Am Board Fam Med · 2011 PURPOSE: Motivational Interviewing (MI) is used to help patients change their behaviors. We sought to determine if physician use of specific MI techniques increases patient satisfaction with the physician and perceived autonomy. METHODS: We audio-recorded ... Full text Link to item Cite

Can prospective usability evaluation predict data errors?

Journal Article AMIA Annu Symp Proc · November 13, 2010 Increasing amounts of clinical research data are collected by manual data entry into electronic source systems and directly from research subjects. For this manual entered source data, common methods of data cleaning such as post-entry identification and r ... Link to item Cite

Effect of home testing of international normalized ratio on clinical events.

Journal Article N Engl J Med · October 21, 2010 BACKGROUND: Warfarin anticoagulation reduces thromboembolic complications in patients with atrial fibrillation or mechanical heart valves, but effective management is complex, and the international normalized ratio (INR) is often outside the target range. ... Full text Open Access Link to item Cite

Influenza vaccination of household contacts of newborns: a hospital-based strategy to increase vaccination rates.

Journal Article Infect Control Hosp Epidemiol · October 2010 We implemented a hospital-based influenza vaccination program for household contacts of newborns. Among mothers not vaccinated prenatally, 44.7% were vaccinated through the program, as were 25.7% of fathers. A hospital-based program provided opportunities ... Full text Open Access Link to item Cite

Physician communication techniques and weight loss in adults: Project CHAT.

Journal Article Am J Prev Med · October 2010 BACKGROUND: Physicians are encouraged to counsel overweight and obese patients to lose weight. PURPOSE: It was examined whether discussing weight and use of motivational interviewing techniques (e.g., collaborating, reflective listening) while discussing w ... Full text Link to item Cite

An evaluation of patient self-testing competency of prothrombin time for managing anticoagulation: pre-randomization results of VA Cooperative Study #481--The Home INR Study (THINRS).

Journal Article J Thromb Thrombolysis · October 2010 Prior studies suggest patient self-testing (PST) of prothrombin time (PT) can improve the quality of anticoagulation (AC) and reduce complications (e.g., bleeding and thromboembolic events). "The Home INR Study" (THINRS) compared AC management with frequen ... Full text Open Access Link to item Cite

Challenges in developing community and clinician partnerships for prevention.

Journal Article J Prim Care Community Health · July 1, 2010 Developing links between primary care practices and community organizations to help manage patients with unhealthy behaviors has been proposed as a strategy to improve health care delivery. The objective of this study was to evaluate easily reproducible in ... Full text Link to item Cite

Representation of women in randomized clinical trials of cardiovascular disease prevention.

Journal Article Circ Cardiovasc Qual Outcomes · March 2010 BACKGROUND: The 2007 American Heart Association guidelines for cardiovascular disease prevention in women drew heavily on results from randomized clinical trials; however, representation of women in trials of cardiovascular disease prevention has not been ... Full text Link to item Cite

Twelve-year follow-up of American women's awareness of cardiovascular disease risk and barriers to heart health.

Journal Article Circ Cardiovasc Qual Outcomes · March 2010 BACKGROUND: Awareness of cardiovascular disease (CVD) risk has been linked to taking preventive action in women. The purpose of this study was to assess contemporary awareness of CVD risk and barriers to prevention in a nationally representative sample of ... Full text Link to item Cite

Economic evaluation of home blood pressure monitoring with or without telephonic behavioral self-management in patients with hypertension.

Journal Article Am J Hypertens · February 2010 BACKGROUND: The Take Control of Your Blood Pressure trial evaluated the effect of a multicomponent telephonic behavioral lifestyle intervention, patient self-monitoring, and both interventions combined compared with usual care on reducing systolic blood pr ... Full text Link to item Cite

Hypertension improvement project: randomized trial of quality improvement for physicians and lifestyle modification for patients.

Journal Article Hypertension · December 2009 Despite widely publicized hypertension treatment guidelines for physicians and lifestyle recommendations for patients, blood pressure control rates remain low. In community-based primary care clinics, we performed a nested, 2 x 2 randomized, controlled tri ... Full text Link to item Cite

Two self-management interventions to improve hypertension control: a randomized trial.

Journal Article Ann Intern Med · November 17, 2009 BACKGROUND: Fewer than 40% of persons with hypertension in the United States have adequate blood pressure (BP) control. OBJECTIVE: To compare 2 self-management interventions for improving BP control among hypertensive patients. DESIGN: A 2 x 2 randomized t ... Full text Link to item Cite

Reporting and representation of race/ethnicity in published randomized trials.

Journal Article Am Heart J · November 2009 BACKGROUND: Although adequate representation of specific subgroups (eg, women and the elderly) in randomized controlled trials (RCTs) has been under intense scrutiny, there are few data on representation by race. METHODS: Using all RCTs cited by the 2007 A ... Full text Link to item Cite

Primary care physicians' discussions of weight-related topics with overweight and obese adolescents: results from the Teen CHAT Pilot study.

Journal Article J Adolesc Health · August 2009 Physicians should counsel overweight adolescents about nutrition and exercise. We audio recorded 30 physician-adolescent encounters. Female, older, normal-weight physicians and pediatricians were more Motivational Interviewing (MI) adherent. When physician ... Full text Link to item Cite

Reporting and Representation of Race in Published Randomized Trials

Journal Article JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY · March 10, 2009 Link to item Cite

Hypertension Improvement Project (HIP): study protocol and implementation challenges.

Journal Article Trials · February 26, 2009 BACKGROUND: Hypertension affects 29% of the adult U.S. population and is a leading cause of heart disease, stroke, and kidney failure. Despite numerous effective treatments, only 53% of people with hypertension are at goal blood pressure. The chronic care ... Full text Open Access Link to item Cite

Cocooning infants: Tdap immunization for new parents in the pediatric office.

Journal Article Acad Pediatr · 2009 OBJECTIVE: Vaccination with tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) is recommended for adults who have close contact with infants aged <12 months to protect young infants from infection due to Bordetella pertussis. This st ... Full text Link to item Cite

Improving influenza vaccine coverage among asthmatics: A practice-based research network study

Journal Article Journal of Clinical Outcomes Management · May 1, 2008 • Objective: To evaluate an educational postcard reminder and practice improvement interventions intended to improve influenza vaccination rates among asthmatic patients. • Design: Pre-post study. • Patients and setting: Patients with asthma followed at 15 ... Cite

Representation of women in randomized clinical trials of cardiovascular disease prevention

Conference JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY · March 11, 2008 Link to item Cite

Closing the gap: treating hypertension in women.

Journal Article Cardiol Rev · 2008 Hypertension is a common and readily modifiable risk factor for cardiovascular and cerebrovascular disease. Despite extensive clinical trial results and efforts to increase public awareness, it remains inadequately controlled in the general population. Wom ... Full text Link to item Cite

Institutional review board training for community practices: advice from the Agency for Health Care Research and Quality Practice-Based Research Network listserv.

Journal Article J Am Board Fam Med · 2008 Human subject protection training is required for all research personnel regardless of funding source. This article summarizes recommendations from a discussion about ethics training for community personnel from the practice-based research network (PBRN) l ... Full text Link to item Cite

Low rates of adherence to 1999 acute otitis media treatment guidelines across pediatric and family practices

Journal Article Journal of Clinical Outcomes Management · November 1, 2007 • Objective: To assess adherence to 1999 guidelines for the treatment of children with acute otitis media (AOM) across primary care specialties and to measure differences across specialties and practice types. • Design: Retrospective record review. • Patie ... Cite

Quality of clinical documentation and anticoagulation control in patients with chronic nonvalvular atrial fibrillation in routine medical care.

Journal Article Am J Med Qual · 2007 Featured Publication OBJECTIVE: Anticoagulation quality and record documentation were retrospectively assessed in patients with chronic nonvalvular atrial fibrillation (CNVAF) managed in a routine care setting. METHODS: Medical record data extraction from physician practices i ... Full text Link to item Cite

The Take Control of Your Blood pressure (TCYB) study: study design and methodology.

Journal Article Contemp Clin Trials · January 2007 Featured Publication BACKGROUND: Among the 65 million Americans with hypertension, only approximately 31% have their blood pressure under control (<140/90 mm/Hg). Despite the damaging impact of hypertension and the availability of evidence-based target values for blood pressur ... Full text Link to item Cite

Quality of life of patients with otitis media and caregivers: a multicenter study.

Journal Article Laryngoscope · October 2006 Featured Publication OBJECTIVE: The objective of this study was to determine the quality of life of otitis media (OM) patients and their caregivers. STUDY DESIGN: A cross-sectional study was conducted at 11 otolaryngology and five pediatric clinics in the United States between ... Full text Link to item Cite

Contents

Journal Article Otolaryngology–Head and Neck Surgery · April 2006 Full text Cite

Clinical practice guideline: acute otitis externa.

Journal Article Otolaryngol Head Neck Surg · April 2006 Featured Publication OBJECTIVE: This guideline provides evidence-based recommendations to manage diffuse acute otitis externa (AOE), defined as generalized inflammation of the external ear canal, which may also involve the pinna or tympanic membrane. The primary purpose is to ... Full text Link to item Cite

The impact of patient self-testing of prothrombin time for managing anticoagulation: rationale and design of VA Cooperative Study #481--the Home INR Study (THINRS).

Journal Article J Thromb Thrombolysis · June 2005 BACKGROUND: Anticoagulation (AC) with warfarin reduces the risk of thromboembolism (TE) in a variety of applications, yet despite compelling evidence of the value and importance of high quality AC, warfarin remains underused, and dosing is often suboptimal ... Full text Link to item Cite

The impact of environmental tobacco smoke on women's risk of dying from heart disease: a meta-analysis.

Journal Article J Womens Health (Larchmt) · October 2004 OBJECTIVE: To review systematically and analyze the association between environmental tobacco smoke (ETS) exposure and the risk of dying from heart disease in women. METHODS: We searched the English-language literature using MEDLINE (1966-April 2004), CINA ... Full text Link to item Cite

A new instrument for measuring anticoagulation-related quality of life: development and preliminary validation.

Journal Article Health Qual Life Outcomes · May 6, 2004 Featured Publication BACKGROUND: Anticoagulation can reduce quality of life, and different models of anticoagulation management might have different impacts on satisfaction with this component of medical care. Yet, to our knowledge, there are no scales measuring quality of lif ... Full text Open Access Link to item Cite

Prescription medication sharing in primary care.

Conference JOURNAL OF GENERAL INTERNAL MEDICINE · April 1, 2004 Link to item Cite

The utility of tolonium chloride rinse in the diagnosis of recurrent or second primary cancers in patients with prior upper aerodigestive tract cancer.

Journal Article Head Neck · November 2003 Featured Publication BACKGROUND: The clinical utility of tolonium chloride rinse was compared with unaided visual examination alone in the diagnosis of oral carcinoma in patients previously treated for carcinoma of the upper aerodigestive tract. METHODS: A total of 668 patient ... Full text Link to item Cite

Antidepressant therapy in primary care: Does patient preference affect response?

Conference JOURNAL OF GENERAL INTERNAL MEDICINE · April 1, 2003 Link to item Cite

Management of allergic rhinitis in the working-age population.

Journal Article Evid Rep Technol Assess (Summ) · January 2003 Featured Publication Link to item Cite

No impact of literacy on glycemic control in type II diabetes mellitus.

Journal Article JOURNAL OF GENERAL INTERNAL MEDICINE · April 1, 2002 Link to item Cite

Efficacy of intranasal corticosteroids for acute sinusitis - Reply

Journal Article JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION · 2002 Cite

Comparison of cefuroxime with or without intranasal fluticasone for the treatment of rhinosinusitis. The CAFFS Trial: a randomized controlled trial.

Journal Article JAMA · December 26, 2001 Featured Publication CONTEXT: It is not known whether intranasal corticosteroids are beneficial to treat acute rhinosinusitis in patients with a history of chronic or recurrent sinus symptoms. OBJECTIVE: To assess whether the addition of an intranasal corticosteroid to antibio ... Full text Link to item Cite

Similar effectiveness of paroxetine, fluoxetine, and sertraline in primary care: a randomized trial.

Journal Article JAMA · December 19, 2001 CONTEXT: Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed class of antidepressant, yet it is not known whether one SSRI is more effective than another. OBJECTIVE: To compare the effectiveness of 3 SSRIs (paroxetine, fluoxeti ... Full text Link to item Cite

Exploring health-related quality of life in patients with diseases of the ear, nose, and throat: a multicenter observational study.

Journal Article Otolaryngol Head Neck Surg · October 2001 Featured Publication OBJECTIVES: This study was undertaken to explore which diseases of the ear, nose, and throat impact daily functioning of patients in an outpatient setting and to observe how specific demographic variables affect health-related quality of life (HRQOL) in th ... Full text Link to item Cite

Prevalence of patients at risk for oropharyngeal cancer in veterans affairs dental clinic

Journal Article Journal of Investigative Medicine · January 1, 1996 Screening for oropharyngeal cancer is recommended for patients considered at risk (patients over 40, and users of tobacco or alcohol). Previous studies also indicate that the presence of an oral symptom predicts malignancy. We surveyed 389 consecutive pati ... Cite

A randomized clinical trial comparing ibuprofen to piroxicam for the relief of chronic non-rheumatic joint pain

Journal Article Journal of Investigative Medicine · January 1, 1996 Nonsteroidal antiinflammatory agents (NSAIDs) demonstrate similar efficacy for chronic joint pain, however they are not equally affordable. We assessed whether patients who preferred a more expensive NSAID, i.e. piroxicam, had better pain relief on this dr ... Cite

Regulation of extracellular calcium entry in endothelial cells: role of intracellular calcium pool.

Journal Article Am J Physiol · January 1992 We have investigated the role of the intracellular Ca2+ pool in regulating Ca2+ entry into vascular endothelial cells. The intracellular Ca2+ pool was mobilized using either thapsigargin (TG) or 2',5'-di(tert-butyl)-1,4-benzohydroquinone (BHQ), inhibitors ... Full text Link to item Cite

Regulation of arachidonic acid release in vascular endothelium. Ca(2+)-dependent and -independent pathways.

Journal Article Biochem J · December 1, 1991 Ca2+ metabolism and its relationship to arachidonic acid release were studied in cultured pig aortic endothelial cells. When cells were treated with bradykinin, a rapid rise in intracellular Ca2+ concentration ([Ca2+]i) occurred. Arachidonic acid release f ... Full text Link to item Cite

MECHANISM OF CALCIUM INFLUX IN ENDOTHELIAL-CELLS

Journal Article CLINICAL RESEARCH · April 1, 1990 Link to item Cite