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"Click and mortar" opportunities for digitization and consumerism in trials.

Publication ,  Journal Article
Randell, RL; Hornik, CP; Curtis, L; Hernandez, AF; Denwood, T; Nebeker, C; Sugarman, J; Tyl, B; Murakami, M; Oley Wilberforce, L; Pagoto, S ...
Published in: Contemp Clin Trials
September 2023

BACKGROUND: Digitization (using novel digital tools and strategies) and consumerism (taking a consumer-oriented approach) are increasingly commonplace in clinical trials, but the implications of these changes are not well described. METHODS: We assembled a group of trial experts from academia, industry, non-profit, and government to discuss implications of this changing trial landscape and provide guidance. RESULTS: Digitization and consumerism can increase the volume and diversity of trial participants and expedite recruitment. However, downstream bottlenecks, challenges with retention, and serious issues with equity, ethics, and security can result. A "click and mortar" approach, combining approaches from novel and traditional trials with the thoughtful use of technology, may optimally balance opportunities and challenges facing many trials. CONCLUSION: We offer expert guidance and three "click and mortar" approaches to digital, consumer-oriented trials. More guidance and research are needed to navigate the associated opportunities and challenges.

Duke Scholars

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Published In

Contemp Clin Trials

DOI

EISSN

1559-2030

Publication Date

September 2023

Volume

132

Start / End Page

107304

Location

United States

Related Subject Headings

  • Public Health
  • General Clinical Medicine
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 11 Medical and Health Sciences
 

Citation

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Randell, R. L., Hornik, C. P., Curtis, L., Hernandez, A. F., Denwood, T., Nebeker, C., … Ranney, M. L. (2023). "Click and mortar" opportunities for digitization and consumerism in trials. Contemp Clin Trials, 132, 107304. https://doi.org/10.1016/j.cct.2023.107304
Randell, Rachel L., Christoph P. Hornik, Lesley Curtis, Adrian F. Hernandez, Tom Denwood, Camille Nebeker, Jeremy Sugarman, et al. “"Click and mortar" opportunities for digitization and consumerism in trials.Contemp Clin Trials 132 (September 2023): 107304. https://doi.org/10.1016/j.cct.2023.107304.
Randell RL, Hornik CP, Curtis L, Hernandez AF, Denwood T, Nebeker C, et al. "Click and mortar" opportunities for digitization and consumerism in trials. Contemp Clin Trials. 2023 Sep;132:107304.
Randell, Rachel L., et al. “"Click and mortar" opportunities for digitization and consumerism in trials.Contemp Clin Trials, vol. 132, Sept. 2023, p. 107304. Pubmed, doi:10.1016/j.cct.2023.107304.
Randell RL, Hornik CP, Curtis L, Hernandez AF, Denwood T, Nebeker C, Sugarman J, Tyl B, Murakami M, Oley Wilberforce L, Pagoto S, Vedin O, Andersson T, Carrasquillo O, Dolor R, Kollins SH, Pellegrino J, Ranney ML. "Click and mortar" opportunities for digitization and consumerism in trials. Contemp Clin Trials. 2023 Sep;132:107304.
Journal cover image

Published In

Contemp Clin Trials

DOI

EISSN

1559-2030

Publication Date

September 2023

Volume

132

Start / End Page

107304

Location

United States

Related Subject Headings

  • Public Health
  • General Clinical Medicine
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 11 Medical and Health Sciences