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Scott Haydn Soderling

George Barth Geller Distinguished Professor of Molecular Biology
Cell Biology
Duke Box 3709, Durham, NC 27710
Nanaline Duke Bldg, Durham, NC 27710

Selected Grants


2/3 CTSA K12 Program at Duke University

ResearchMentor · Awarded by National Institutes of Health · 2025 - 2030

Soderling Mentorship

ResearchPrincipal Investigator · Awarded by Chan Zuckerberg Initiative · 2024 - 2029

Neurobiology Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institute of Neurological Disorders and Stroke · 2024 - 2029

Duke-NCCU Interdisciplinary Postdoctoral Training Program in Child Psychiatric and Neurodevelopmental Conditions Program (DN-IPT)

Inst. Training Prgm or CMEPreceptor · Awarded by National Institute of Mental Health · 2024 - 2029

Chromatin dysregulation in neurodevelopmental disorders

ResearchCollaborator · Awarded by National Institute of Neurological Disorders and Stroke · 2024 - 2029

Duke Preparing Research Scholars in Biomedical Sciences- Post-Baccalaureate Research Education Program

Inst. Training Prgm or CMEMentor · Awarded by National Institute of General Medical Sciences · 2022 - 2027

Molecular Analysis of Developmental Brain Disorders Associated with Synaptic Pathology

ResearchPrincipal Investigator · Awarded by National Institute of Mental Health · 2022 - 2027

Training Program in Developmental and Stem Cell Biology

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2001 - 2027

Revealing the hidden topologies of the human kinome

ResearchPrincipal Investigator · Awarded by Chan Zuckerberg Initiative · 2023 - 2026

CIRCUIT MECHANISMS FOR DOPAMINE NEURON VULNERABILITY AND RESILIENCE IN PD - Extension

ResearchCo Investigator · Awarded by Michael J. Fox Foundation for Parkinson's Research · 2021 - 2026

Linking Neuron-Astrocyte Communication to Long-Term Changes in Neural Circuit Function and Behavior

ResearchCollaborating Investigator · Awarded by Salk Institute Biotechnology/Industrial Associatio · 2021 - 2026

Cell and Molecular Biology Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institute of General Medical Sciences · 2021 - 2026

Proteomic and Functional Analysis of Presynaptic Physiology and Plasticity

ResearchPrincipal Investigator · Awarded by National Institute of Mental Health · 2021 - 2026

Unbiased Spatial Mapping of Neurodegenerative Proteome in Parkinson's Disease

FellowshipPrincipal Investigator · Awarded by PhRMA Foundation · 2024 - 2025

Genetic and Genomics Training Grant

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2020 - 2025

Multi-omics functional analysis of non-coding regulatory genome for genomic medicine

ResearchCollaborator · Awarded by National Human Genome Research Institute · 2020 - 2025

Investigating the role of RNP granules during heart regeneration in the zebrafish

ResearchCo-Mentor · Awarded by American Heart Association · 2022 - 2025

Duke CTSA (TL1) Year 5

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2018 - 2024

Epitranscriptomic Regulation of Synaptic Responses to Drugs of Abuse

ResearchCollaborating Investigator · Awarded by National Institutes of Health · 2018 - 2024

HHMI Hanna H. Gray Fellows Program: Mitochondrial surveillance in neuronal homeostasis and disease

ResearchMentor · Awarded by Howard Hughes Medical Institute · 2021 - 2024

Identifying Endogenous Proteomes and Polygenic Dysregulations Associated with Synaptic Schizophrenia Risk Genes

ResearchMentor · Awarded by Brain and Behavior Research Foundation · 2022 - 2024

Analysis of Inhibitory Synaptic Proteins Associated with Brain Disorders

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2017 - 2023

Phospho-regulation as a driver of inhibitory synapse function

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2021 - 2022

Medical Scientist Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1997 - 2022

Zeiss Lightsheet Upgrade to Expand Imaging Capabilities

EquipmentMajor User · Awarded by National Institutes of Health · 2021 - 2022

Control of Astrocyte Morphogenesis and Synaptogenesis by Astrocytic Neuroligins

FellowshipCo-Sponsor · Awarded by National Institutes of Health · 2019 - 2022

Interneuron Synapses: In Vivo Chemicogenetic Proteomics to Discover Developmental Brain Disorder Etiologies

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2019 - 2022

New Proteomic and Genome Engineering Approaches to Decipher Astrocyte Function at Synapses

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2021

Super-resolution Imaging via Multiple Modalities with the Zeiss Elyra 7

EquipmentPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2021

Interrogating the role of the novel synaptic protein Rogdi in GABAergic inhibition and epilepsy

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2019 - 2021

Genetics Training Grant

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1979 - 2020

Organization and Function of Cellular Structure

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1975 - 2020

How Does Huntingtin Control Synaptic Development?

FellowshipCo-Mentor · Awarded by National Institutes of Health · 2018 - 2020

Molecular, Synaptic, and Circuit Basis for Schizophrenia-related Phenotypes

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2014 - 2020

Thermo Lumos Tribrid High-Resolution Accurate-Mass Tandem Mass Spectrometer

EquipmentMajor User · Awarded by National Institutes of Health · 2018 - 2019

Chemico-genetic analysis of serotonergic circuits and synapses

ResearchPrincipal Investigator · Awarded by Ruth K. Broad Biomedical Research Foundation · 2018 - 2019

Control of cell fate by progenitor mitosis length and microcephaly-linked genes during cortical development

FellowshipCo-Sponsor · Awarded by National Institutes of Health · 2017 - 2019

Unveiling Brain Circuits of Abnormal Social Behavior

ResearchPrincipal Investigator · Awarded by Brain and Behavior Research Foundation · 2017 - 2019

Basic predoctoral training in neuroscience

Inst. Training Prgm or CMETraining Faculty · Awarded by National Institutes of Health · 1992 - 2018

Fragile X Phenotypes Modulated by Altered Signaling to the Synaptic Cytoskeleton

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2014 - 2018

Analysis of Arp2/3 activity as a major driver of dendritic spinogenesis

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2015 - 2018

Quantitative Analysis of the Postsynaptic Inhibitory Complex In Vivo

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2015 - 2017

Synaptic plasticity

ResearchCo Investigator · Awarded by Max Planck Institute · 2013 - 2016

Training in Fundamental &Translational Neuroscience

Inst. Training Prgm or CMETraining Faculty · Awarded by National Institutes of Health · 2005 - 2016

Agilent Direct Drive 9.4T MRS/MRI Console

EquipmentMajor User · Awarded by National Institutes of Health · 2012 - 2013

The effects of Nlrp12 and IL-1b in inflammatory disorders

ResearchCollaborator · Awarded by National Institutes of Health · 2010 - 2012

Mapping the Architecture of Cancer Signaling Pathways

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2009 - 2012

External Relationships


  • Albert Einstein College of Medicine
  • Duke -National Univeristy of Singapore
  • Emory University School of Medicine
  • Japan Neuroscience Society

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.