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Simon Gray Gregory

Margaret Harris and David Silverman Distinguished Professor
Neurosurgery, Neuro-Oncology
Duke Box 104775, Durham, NC 27701
300 N. Duke Street, Room 51-102, Duke Molecular Physiology Institute, Durham, NC 27701

Selected Presentations & Appearances


Characterizing oxysterol regulation of inflamation and mediators of remyelination in MS - 10x Genomics User Group Meeting · October 2018 Invited Talk Emory University
Characterizing Oxysterols as moderators of inflammation and mediators of remyelination in MS · July 2018 Invited Talk University of Sydney, Sydney, Australia
Characterizing Oxysterols as moderators of inflammation and mediators of remyelination in MS · July 2018 International Meeting or Conference Duke - National University of Singapore, Singapore
Epistatic interaction with IL7R and the development of MS - Epigenetics and Stem Cell Biology Laboratory Seminar Series · September 2017 Invited Talk NIEHS,
Developing biomarkers and mechanisms of oxytocin use in autism · February 2017 Invited Talk University of Sydney, Sydney, Australia
Developing biomarkers and mechanisms of oxytocin use in autism - Autism Symposium · January 2017 International Meeting or Conference Duke - National University of Singapore, Singapore
Molecular profiling of an Oxytocin Treatment trial - a first pass view · February 2016 Invited Talk University of Sydney, Sydney, Australia
MicroRNA profiling in an animal model of multiple sclerosis - Epigenomics of Common Diseases · November 2015 Invited Talk Wellcome Trust, Hinxton, UK
The identification of genetic association and regulation of IL7R in an autoimmune disease · September 2015 Invited Talk Pfizer, San Francisco, CA
Autoimmune Genes: Discovery & Function - ASHG Annual Meeting · October 2014 National Scientific Meeting San Diego, CA
Genetics of Multiple Sclerosis - current state and future developments · July 2014 International Meeting or Conference University of Basel, Basel, Switzerland
The functional characterization of a multiple sclerosis associated variant in IL7Ra · June 2014 Invited Talk University of North Carolina - Chapel Hill, Chapel Hill, NC
Leveraging epigenomics to understand the etiology of CVD - Duke Cardiovascular Research Center Seminar Series · June 2013 Invited Talk Durham, NC
In Pursuit of Mechanism - From Association to Function in Multiple Sclerosis - Spring Seminar Series · March 2013 Invited Talk The Jackson Laboratory, Bar Harbor, ME
The role of IL7R splicing in the etiology of MS - Carolinas Research Symposium · August 2012 Invited Talk National Multiple Sclerosis Society, Durham, NC
Epigenetic Association of OXTR with Autism - 67th Annual Meeting · May 2012 National Scientific Meeting Society of Biological Psychiatry, Philadelphia. PA
Epigenetic Profiling in Autism – The Case for Targeted and Discovery Approaches - Investigator Forum Series · March 2012 Invited Talk University of North Carolina - Chapel Hill, Chapel Hill, NC
Genetic Variation and Multiple Sclerosis · November 2011 Invited Talk National MS Society - Greater Delaware Valley Chapter, Conhsohocken, PA
Genomic rearrangements in autism · October 2011 Invited Talk Environmental Mutagen Society, Montreal, Quebec, Canada
Genetics of Chiari Type 1 Malformation · July 2011 National Scientific Meeting American Syringommyelia & Chiari Alliance Project, Denver, CO
Genomic and epigenetic signatures of OXTR and autism · July 2011 International Meeting or Conference World Congress on Neurophysical Hormones, Boston, MA
The Genetics and Genomic Sciences of Neurological Disease - Transcending the Boundaries Workshop on Neurodevelopment · May 2010 Instructional Course, Workshop, or Symposium Duke University Institute of Brain Science, Durham, NC
Epigenetic Evidence of Oxytocin Receptor Deficiency in Autism · April 2010 Invited Talk Autism Research Institute, Baltimore, MA
Establishing the role of IL-7R in the development of MS · April 2010 Invited Talk University of California San Francisco, San Francisco, CA
Epigenetic evidence of oxytocin receptor deficiency in autism - Think Tank Meeting · January 2010 Invited Talk Autism Research Institute, Dallas, TX

Outreach & Engaged Scholarship


Faculty Mentor - Durham School of the Arts Independent Study Partnership with DMPI · 2014 - 2022 Research

Service to the Profession


Academic and Scientific Advisor · 2018 - 2020 Consulting David H. Murdock Research Institute,
Reviewer - Research Development Grant Program · 2018 Committee Service Kansas City Area Life Sciences Institute (KCALSI),
International Review Committee Member · 2016 - 2017 Committee Service Multiple Sclerosis Society Research Foundation, Canada,
Member - Pilot Grant Review Committee · 2016 - 2017 Committee Service National Multiple Sclerosis Society,
Standing Member - Special Emphasis Panel/Scientific Review Group 2015/05 NSD-C Neurological Sciences and Disorders C · 2015 - 2020 Committee Service National Institutes of Health, Center for Scientific Review,
Ad Hoc Reviewer - Research Competitiveness Program · 2014 Committee Service American Association for the Advancement of Science,
Ad Hoc Reviewer - Cancer, Cardiovascular, and Sleep Epidemiology Panel B (CASE) · 2013 - 2016 Committee Service National Institutes of Health, Center for Scientific Review,
Ad Hoc Reviewer - National Priorities Research Program · 2013 - 2015 Committee Service Quatar National Research Foundation,
Awards Reviewer - Charles J. Epstein Trainee Awards for Excellence in Human Genetics · 2013 - 2016 Committee Service American Society of Human Genetics,
Editorial Board Member · 2013 - 2017 Editorial Activities Frontiers in Neurogenomics,
Director, Genomics Core Facility · 2010 - 2018 Event/Organization Administration David H. Murdock Research Institute,
Member · 2003 - 2020 Committee Service American Society of Human Genetics,
Editor, Chromosome 1 · 1996 - 2003 Other Human Genome Organization,

Service to Duke


Chair, Precision Medicine and Genetics and Genomics Subcommittee (School) · 2018 Committee Service Research Planning Committee, Duke School of Medicine,
Duke University Center for Neurodegeneration and Neurotherapeutics (University) · 2018 - 2022 Committee Service
Research Planning Committee (School) · 2017 - 2018 Committee Service Duke University School of Medicine,
Director Search Committee (Clinical Organization) · 2015 - 2017 Committee Service Duke Institute of Brain Sciences,
Executive Counsel of Core Directors (University) · 2015 - 2022 Committee Service
Duke Pathway to Independence and K-club Review Panel (University) · 2015 - 2020 Committee Service
Executive Committee Member . Duke Epigenetics and Epigenomics Program (DEEP) · 2011 - 2020 Curriculum Innovations
Charter Member · 2011 - 2022 Curriculum Innovations Duke University Cardiovascular Research Center,
Executive Committee Member · 2011 - 2020 Curriculum Innovations Program in Genetics and Genomics,
Co-Leader . Epigenetics and Epigenomics Focus Group (Genetics and Genomics Basic Sciences Program) · 2011 - 2014 Curriculum Innovations Duke University Cancer Institute,
Chair, Admissions Committee (Program) · 2011 - 2014 Committee Service Program in Genetics and Genomics,
Seminar Committee (Program) · 2010 - 2014 Committee Service Program in Genetics and Genomics,
Admissions Committee (Program) · 2003 - 2020 Committee Service Program in Genetics and Genomics,

Academic & Administrative Activities


Director - Brain Tumor Omics Program - 2022-present
Director - Duke Center for Research in Autoimmunity and Multiple Sclerosis, Department of Neurology - 2015- present
Founding Co-Director
- Duke Epigenetics an Epigenomics Program (DEEP) 2011-2019

Chair - Duke University Executive Committee of the Graduate Faculty - 2021-present
Member
 - Duke University Executive Committee of the Graduate Faculty - 2020-2021
Director of Graduate Studies
 - Duke University Program of Genetics and Genomics 2017-2020
Co-Director
 - Duke University Program of Genetics and Genomics Basic Sciences Program 2014-2017
Chair
 - Duke University Program in Genetics and Genomics, Admissions Committee 2011-2014
Member - 
Duke University Program in Genetics and Genomics, Admissions Committee 2005-2011   
    
Board of Directors
- David H Murdock Research Institute – 2019-present
Member - Duke Center for Applied Genomic Technologies - 2019 - present
Member
- Duke University Center for Neurodegeneration and Neurotherapeutics – 2018-present   
Member
- Duke University Executive Counsel of Core Directors - 2015-present   
Research Affiliate
 - Duke University Center for Autism and Brain Development - 2015-present 
Member
- Duke University Cardiovascular Research Center – 2014-present
Section Director - Duke Molecular Physiology Institute, Genomics and Epigenetics - 2014-present   
Director and Instructor - Duke Bioinformatics Workshop 2004-2013