Skip to main content

Mary Scott Campbell Soo

Professor of Radiology
Radiology, Breast Imaging
Box 3808 Med Ctr, Durham, NC 27710
Duke South Clinic, Blue Zone, Room 2521, Durham, NC 27710

Selected Publications


Now or Later? Patient Satisfaction and Anxiety Among Women Undergoing Breast Biopsies Performed the Same Day as Recommended Versus a Later Day.

Journal Article J Am Coll Radiol · March 2024 PURPOSE: The aim of this study was to determine differences in patient satisfaction and anxiety among women undergoing core-needle breast biopsies performed the same day as recommended versus a future date. METHODS: After institutional review board exempti ... Full text Link to item Cite

Managing Challenging Patient Interactions in Breast Imaging.

Journal Article J Breast Imaging · April 15, 2022 Managing challenging patient interactions can be a daily stressor for breast imaging radiologists, leading to burnout. This article offers communication and behavioral practices for radiologists that help reduce radiologists' stress during these encounters ... Full text Link to item Cite

Mixed-Methods Study to Predict Upstaging of DCIS to Invasive Disease on Mammography.

Journal Article AJR Am J Roentgenol · April 2021 BACKGROUND. The incidence of ductal carcinoma in situ (DCIS) has steadily increased, as have concerns regarding overtreatment. Active surveillance is a novel treatment strategy that avoids surgical excision, but identifying patients with occult invasive di ... Full text Link to item Cite

Molecular Subtypes of Breast Cancer: A Review for Breast Radiologists.

Journal Article J Breast Imaging · January 26, 2021 Gene expression profiling has reshaped our understanding of breast cancer by identifying four molecular subtypes: (1) luminal A, (2) luminal B, (3) human epidermal growth factor receptor 2 (HER2)-enriched, and (4) basal-like, which have critical difference ... Full text Link to item Cite

Breast Imaging: Screening for New Breast Cancers and for Cancer Recurrence

Chapter · January 1, 2021 Breast cancer survivors require a unique breast imaging approach to identify new cancers as well as cancer recurrences. In this patient population, appropriate imaging requires some combination of digital mammography, digital breast tomosynthesis, ultrasou ... Full text Cite

Predicting Upstaging of DCIS to Invasive Disease: Radiologists's Predictive Performance.

Journal Article Acad Radiol · November 2020 RATIONALE AND OBJECTIVES: The purpose of this study is to quantify breast radiologists' performance at predicting occult invasive disease when ductal carcinoma in situ (DCIS) presents as calcifications on mammography and to identify imaging and histopathol ... Full text Link to item Cite

Ductal Carcinoma In Situ Biology, Language, and Active Surveillance: A Survey of Breast Radiologists' Knowledge and Opinions.

Journal Article J Am Coll Radiol · October 2020 PURPOSE: To understand how breast radiologists perceive ductal carcinoma in situ (DCIS). MATERIALS AND METHODS: A 19-item survey was developed by the Society of Breast Imaging Patient Care and Delivery Committee and distributed to all Society of Breast Ima ... Full text Link to item Cite

Unmet Spiritual Care Needs in Women Undergoing Core Needle Breast Biopsy.

Journal Article J Breast Imaging · March 25, 2020 OBJECTIVE: Spiritual care is an important part of healthcare, especially when patients face a possible diagnosis of a life-threatening disease. This study examined the extent to which women undergoing core-needle breast biopsy desired spiritual support and ... Full text Link to item Cite

Dreams prior to biopsy for suspected breast cancer: A preliminary survey.

Journal Article Explore (NY) · 2020 Warning dreams prior to the onset of symptoms have been reported in a previous survey of self-selected women with breast cancer. There is no available data on how many women with suspected breast cancer have such dreams, so anonymous surveys were offered t ... Full text Link to item Cite

Frequency of Breast Cancer Thoughts and Lifetime Risk Estimates: A Multi-Institutional Survey of Women Undergoing Screening Mammography.

Journal Article J Am Coll Radiol · October 2019 PURPOSE: The aim of this study was to quantify women's personal estimates of breast cancer risk and frequency of breast cancer thoughts. METHODS: Women from five medical centers were surveyed before their screening mammographic examinations. Participants w ... Full text Link to item Cite

Preliminary efficacy of a lovingkindness meditation intervention for patients undergoing biopsy and breast cancer surgery: A randomized controlled pilot study.

Journal Article Support Care Cancer · September 2019 PURPOSE: Despite more women undergoing treatment for breast cancer and increased survival rates, many women suffer from anxiety and physical symptoms (e.g., pain, fatigue) surrounding diagnosis and surgery. Research investigating the efficacy of psychosoci ... Full text Link to item Cite

Machine learning-based prediction of future breast cancer using algorithmically measured background parenchymal enhancement on high-risk screening MRI.

Journal Article J Magn Reson Imaging · August 2019 BACKGROUND: Preliminary work has demonstrated that background parenchymal enhancement (BPE) assessed by radiologists is predictive of future breast cancer in women undergoing high-risk screening MRI. Algorithmically assessed measures of BPE offer a more pr ... Full text Link to item Cite

Screening Guidelines and Supplemental Screening Tools: Assessment of the Adequacy of Patient-Provider Discussions.

Journal Article J Breast Imaging · June 4, 2019 PURPOSE: To assess breast imaging radiologists' perceptions of the adequacy of provider-patient discussions regarding the benefits and risks of screening mammography and supplemental screening in women with elevated risk and dense breasts. METHODS: A 36-it ... Full text Link to item Cite

Optimizing the Patient Experience during Breast Biopsy.

Journal Article J Breast Imaging · June 4, 2019 For years, breast imaging has been the model in radiology for patient communication, and more recently, it has been a leader in the growing patient- and family-centered approach to care. To maintain high levels of patient satisfaction during image-guided c ... Full text Link to item Cite

Radiologist-Patient Communication: Current Practices and Barriers to Communication in Breast Imaging.

Journal Article J Am Coll Radiol · May 2019 PURPOSE: The aim of this study was to assess variability in radiologist-patient communication practices and barriers to communication among members of the Society of Breast Imaging (SBI). METHODS: A 36-item questionnaire developed by the SBI Patient Care a ... Full text Link to item Cite

Persistent breast pain in post-surgery breast cancer survivors and women with no history of breast surgery or cancer: associations with pain catastrophizing, perceived breast cancer risk, breast cancer worry, and emotional distress.

Journal Article Acta Oncol · May 2019 Background: Persistent breast pain (PBP) is prevalent among breast cancer survivors and has powerful negative psychological consequences. The present study provided a first test of the hypothesis that: (a) pain catastrophizing, (b) heightened perceived ris ... Full text Link to item Cite

Exploiting heat shock protein expression to develop a non-invasive diagnostic tool for breast cancer.

Journal Article Sci Rep · March 5, 2019 Leveraging the unique surface expression of heat shock protein 90 (Hsp90) in breast cancer provides an exciting opportunity to develop rapid diagnostic tests at the point-of-care setting. Hsp90 has previously been shown to have elevated expression levels a ... Full text Link to item Cite

Relationship between Background Parenchymal Enhancement on High-risk Screening MRI and Future Breast Cancer Risk.

Journal Article Acad Radiol · January 2019 RATIONALE AND OBJECTIVES: To determine if background parenchymal enhancement (BPE) on screening breast magnetic resonance imaging (MRI) in high-risk women correlates with future cancer. MATERIALS AND METHODS: All screening breast MRIs (n = 1039) in high-ri ... Full text Link to item Cite

Patient Perceptions of Breast Cancer Risk in Imaging-Detected Low-Risk Scenarios and Thresholds for Desired Intervention: A Multi-Institution Survey.

Journal Article J Am Coll Radiol · June 2018 PURPOSE: To determine women's perceptions of breast cancer risk and thresholds for desiring biopsy when considering BI-RADS 3 and 4A scenarios and recommendations, respectively. MATERIALS AND METHODS: Women presenting for screening mammography from five ge ... Full text Link to item Cite

The relationship between holding back from communicating about breast concerns and anxiety in the year following breast biopsy.

Journal Article J Psychosoc Oncol · 2018 PURPOSE: Evidence suggests open communication about breast cancer concerns promotes psychological adjustment, while holding back can lead to negative outcomes. Little is known about the relationship between communication and distress following breast biops ... Full text Link to item Cite

Optimizing fluorescently-tethered Hsp90 inhibitor dose for maximal specific uptake by breast tumors

Conference Progress in Biomedical Optics and Imaging - Proceedings of SPIE · January 1, 2018 Despite improvements in surgical resection, 20-40% of patients undergoing breast conserving surgery require at least one additional re-excision. Leveraging the unique surface expression of heat shock protein 90 (Hsp90), a chaperone protein involved in seve ... Full text Cite

Leveraging ectopic Hsp90 expression to assay the presence of tumor cells and aggressive tumor phenotypes in breast specimens.

Journal Article Sci Rep · December 13, 2017 Hsp90 has been studied extensively as a therapeutic target in breast cancer in pre-clinical and clinical trials, demonstrating a variety of roles in metastatic progression. The evidence to date suggests a compelling opportunity to leverage attributes of Hs ... Full text Link to item Cite

Positive and negative mood following imaging-guided core needle breast biopsy and receipt of biopsy results.

Journal Article Psychol Health Med · December 2017 Positive and negative mood are independent psychological responses to stressful events. Negative mood negatively impacts well-being and co-occurring positive mood leads to improved adjustment. Women undergoing core needle breast biopsies (CNB) experience d ... Full text Link to item Cite

Imaging Features of Patients Undergoing Active Surveillance for Ductal Carcinoma in Situ.

Journal Article Acad Radiol · November 2017 RATIONALE AND OBJECTIVES: The aim of this study was to describe the imaging appearance of patients undergoing active surveillance for ductal carcinoma in situ (DCIS). MATERIALS AND METHODS: We retrospectively identified 29 patients undergoing active survei ... Full text Link to item Cite

Relationships Between MRI Breast Imaging-Reporting and Data System (BI-RADS) Lexicon Descriptors and Breast Cancer Molecular Subtypes: Internal Enhancement is Associated with Luminal B Subtype.

Journal Article Breast J · September 2017 The aim of this study was to determine the associations between breast MRI findings using the Breast Imaging-Reporting and Data System (BI-RADS) lexicon descriptors and breast cancer molecular subtypes. In this retrospective, IRB-approved, single instituti ... Full text Link to item Cite

Impact of Sodium Bicarbonate-Buffered Lidocaine on Patient Pain During Image-Guided Breast Biopsy.

Journal Article J Am Coll Radiol · September 2017 PURPOSE: This randomized, double-blind controlled study evaluated the effectiveness of sodium bicarbonate-buffered lidocaine on reducing pain during imaging-guided breast biopsies. MATERIALS AND METHODS: This prospective, HIPAA-compliant study randomly ass ... Full text Link to item Cite

Suspicious breast calcifications undergoing stereotactic biopsy in women ages 70 and over: Breast cancer incidence by BI-RADS descriptors.

Journal Article Eur Radiol · June 2017 OBJECTIVES: To determine the malignancy rate overall and for specific BI-RADS descriptors in women ≥70 years who undergo stereotactic biopsy for calcifications. METHODS: We retrospectively reviewed 14,577 consecutive mammogram reports in 6839 women ≥70 yea ... Full text Link to item Cite

Anxiety prior to breast biopsy: Relationships with length of time from breast biopsy recommendation to biopsy procedure and psychosocial factors.

Journal Article J Health Psychol · April 2017 This study investigated how time from breast biopsy recommendation to biopsy procedure affected pre-biopsy anxiety ( N = 140 women), and whether the relationship between wait time and anxiety was affected by psychosocial factors (chronic life stress, traum ... Full text Link to item Cite

Persistent Breast Pain Among Women With Histories of Breast-conserving Surgery for Breast Cancer Compared With Women Without Histories of Breast Surgery or Cancer.

Journal Article Clin J Pain · January 2017 OBJECTIVES: This study compared persistent breast pain among women who received breast-conserving surgery for breast cancer and women without a history of breast cancer. METHODS: Breast cancer survivors (n=200) were recruited at their first postsurgical su ... Full text Link to item Cite

Patient Anxiety Before and Immediately After Imaging-Guided Breast Biopsy Procedures: Impact of Radiologist-Patient Communication.

Journal Article J Am Coll Radiol · November 2016 PURPOSE: The aim of this study was to evaluate patient anxiety and its association with perceived radiologist-patient communication in the setting of imaging-guided breast biopsy. METHODS: After informed consent was obtained, 138 women recommended for imag ... Full text Link to item Cite

Imaging-Guided Core-Needle Breast Biopsy: Impact of Meditation and Music Interventions on Patient Anxiety, Pain, and Fatigue.

Journal Article J Am Coll Radiol · May 2016 PURPOSE: To evaluate the impact of guided meditation and music interventions on patient anxiety, pain, and fatigue during imaging-guided breast biopsy. METHODS: After giving informed consent, 121 women needing percutaneous imaging-guided breast biopsy were ... Full text Link to item Cite

Abbreviated screening protocol for breast MRI: a feasibility study.

Journal Article Acad Radiol · September 2015 RATIONALE AND OBJECTIVES: To compare the performance of two shortened breast magnetic resonance imaging (MRI) protocols to a standard MRI protocol for breast cancer screening. MATERIALS AND METHODS: In this Health Insurance Portability and Accountability A ... Full text Link to item Cite

ANXIETY AND NEGATIVE MOOD FOLLOWING MAMMOGRAPHY SCREENING FOR BREAST CANCER

Journal Article ANNALS OF BEHAVIORAL MEDICINE · April 1, 2015 Link to item Cite

Can breast cancer molecular subtype help to select patients for preoperative MR imaging?

Journal Article Radiology · February 2015 PURPOSE: To assess whether breast cancer molecular subtype classified by surrogate markers can be used to predict the extent of clinically relevant disease with preoperative breast magnetic resonance (MR) imaging. MATERIALS AND METHODS: In this HIPAA-compl ... Full text Link to item Cite

Predictors of pain experienced by women during percutaneous imaging-guided breast biopsies.

Journal Article J Am Coll Radiol · July 2014 PURPOSE: The purpose of this study was to evaluate pain experienced during imaging-guided core-needle breast biopsies and to identify factors that predict increased pain perception during procedures. METHODS: In this institutional review board-approved, HI ... Full text Link to item Cite

Persistent pain following breast cancer surgery: A case-control study.

Conference Journal of Clinical Oncology · May 20, 2014 Full text Cite

Patient anxiety before and immediately after imaging-guided breast biopsy procedures: impact of radiologist-patient communication.

Journal Article J Am Coll Radiol · June 2013 PURPOSE: The aim of this study was to evaluate patient anxiety and its association with perceived radiologist-patient communication in the setting of imaging-guided breast biopsy. METHODS: After informed consent was obtained, 138 women recommended for imag ... Full text Link to item Cite

Cancelation of MRI guided breast biopsies for suspicious breast lesions identified at 3.0 T MRI: reasons, rates, and outcomes.

Journal Article Acad Radiol · May 2013 RATIONALE AND OBJECTIVES: To determine the cancelation rate of magnetic resonance imaging (MRI)-guided procedures in suspicious breast lesions initially detected at 3.0 Tesla (T) MRI. MATERIALS AND METHODS: With institutional review board approval, a Healt ... Full text Link to item Cite

Suspicious breast lesions detected at 3.0 T magnetic resonance imaging: clinical and histological outcomes.

Journal Article Acad Radiol · June 2012 RATIONALE AND OBJECTIVES: To evaluate the imaging features and histological and clinical outcomes of a series of suspicious, mammographically occult breast lesions detected at 3.0 T magnetic resonance imaging (MRI). MATERIALS AND METHODS: Approval was obta ... Full text Link to item Cite

Using the BI-RADS lexicon in a restrictive form of double reading as a strategy for minimizing screening mammography recall rates.

Journal Article AJR Am J Roentgenol · April 2012 OBJECTIVE: The purpose of this article is to determine the potential reduction in screening recall rates by strictly following standardized BI-RADS lexicon for lesions seen on screening mammography. MATERIALS AND METHODS: Of 3084 consecutive mammograms per ... Full text Link to item Cite

Prospective study of factors predicting adherence to surveillance mammography in women treated for breast cancer.

Journal Article J Clin Oncol · March 10, 2012 PURPOSE: This prospective study examined the factors that predicted sustained adherence to surveillance mammography in women treated for breast cancer. METHODS: Breast cancer survivors (N = 204) who were undergoing surveillance mammography completed questi ... Full text Link to item Cite

Breast imaging

Chapter · January 19, 2012 Cite

Breast imaging: Case 9

Chapter · January 19, 2012 Cite

Breast imaging: Case 2

Chapter · January 19, 2012 Cite

Breast imaging: Case 12

Chapter · January 19, 2012 Cite

Breast imaging: Case 6

Chapter · January 19, 2012 Cite

Breast imaging: Case 3

Chapter · January 19, 2012 Cite

Breast imaging: Case 1

Chapter · January 19, 2012 Cite

Breast imaging: Case 4

Chapter · January 19, 2012 Cite

Breast imaging: Case 8

Chapter · January 19, 2012 Cite

Breast imaging: Case 13

Chapter · January 19, 2012 Cite

Breast imaging: Case 16

Chapter · January 19, 2012 Cite

Breast imaging: Case 20

Chapter · January 19, 2012 Cite

Breast imaging: Case 24

Chapter · January 19, 2012 Cite

Breast imaging: Case 23

Chapter · January 19, 2012 Cite

Breast imaging: Case 21

Chapter · January 19, 2012 Cite

Breast imaging: Case 14

Chapter · January 19, 2012 Cite

Breast imaging: Case 11

Chapter · January 19, 2012 Cite

Breast imaging: Case 5

Chapter · January 19, 2012 Cite

Breast imaging: Case 15

Chapter · January 19, 2012 Cite

Breast imaging: Case 17

Chapter · January 19, 2012 Cite

Breast imaging: Case 19

Chapter · January 19, 2012 Cite

Breast imaging: Case 7

Chapter · January 19, 2012 Cite

Breast imaging: Case 10

Chapter · January 19, 2012 Cite

Breast imaging: Case 22

Chapter · January 19, 2012 Cite

Comparative performance of multiview stereoscopic and mammographic display modalities for breast lesion detection.

Journal Article Med Phys · April 2011 PURPOSE: Mammography is known to be one of the most difficult radiographic exams to interpret. Mammography has important limitations, including the superposition of normal tissue that can obscure a mass, chance alignment of normal tissue to mimic a true le ... Full text Link to item Cite

Breast self-examination: defining a cohort still in need.

Journal Article Am J Surg · October 2009 BACKGROUND: The value of breast self-examination (BSE) to detect early breast cancer is controversial. METHODS: Within an institutional review board-approved prospective study, 147 high-risk women were enrolled from 2004 to 2007. Yearly clinical examinatio ... Full text Link to item Cite

The influence of increased ambient lighting on mass detection in mammograms.

Journal Article Acad Radiol · March 2009 RATIONALE AND OBJECTIVES: Recent research has provided evidence that in reading rooms equipped with liquid crystal displays (LCDs), a measured increase of ambient lighting may improve clinicians' detection performance. In agreement with this research, the ... Full text Link to item Cite

Comparison of LCD and CRT displays based on efficacy for digital mammography.

Journal Article Acad Radiol · November 2006 RATIONALE AND OBJECTIVES: To compare two display technologies, cathode ray tube (CRT) and liquid crystal display (LCD), in terms of diagnostic accuracy for several common clinical tasks in digital mammography. MATERIALS AND METHODS: Simulated masses and mi ... Full text Link to item Cite

Adaptive imaging on a diagnostic ultrasound scanner at quasi real-time rates.

Journal Article IEEE Trans Ultrason Ferroelectr Freq Control · October 2006 Constructing an ultrasonic imaging system capable of compensating for phase errors in real-time is a significant challenge in adaptive imaging. We present a versatile adaptive imaging system capable of updating arrival time profiles at frame rates of appro ... Full text Link to item Cite

MRI-guided vacuum-assisted breast biopsy with a handheld portable biopsy system.

Journal Article AJR Am J Roentgenol · June 2006 OBJECTIVE: The purpose of this study was to evaluate a compact portable 10-gauge handheld battery-operated vacuum-assisted biopsy system for MRI-guided breast biopsy. CONCLUSION: The compact portable battery-operated biopsy system can be used successfully ... Full text Link to item Cite

Streaming detection for evaluation of indeterminate sonographic breast masses: a pilot study.

Journal Article AJR Am J Roentgenol · May 2006 OBJECTIVE: Streaming detection is a novel sonography technique that uses ultrasonic energy to induce movement in cyst fluid that is detected on Doppler sonography. This pilot study evaluates the utility of streaming detection for differentiating cysts from ... Full text Link to item Cite

Reply [2]

Journal Article American Journal of Roentgenology · March 1, 2006 Full text Cite

Image processing and data acquisition optimization for Acoustic Radiation Force Impulse imaging of in vivo breast masses

Conference Progress in Biomedical Optics and Imaging - Proceedings of SPIE · September 19, 2005 Acoustic Radiation Force Impulse (ARFI) imaging utilizes brief, high-energy acoustic pulses to excite tissue and ultrasonic correlation based tracking methods to monitor the resulting tissue displacement, which reflects the relative mechanical properties o ... Full text Cite

Spatial and temporal aberrator stability for real-time adaptive imaging.

Journal Article IEEE Trans Ultrason Ferroelectr Freq Control · September 2005 Reported real-time adaptive imaging systems use near-field phase correction techniques, which are desired because of their simple implementation and their compatibility with current system architectures. Aberrator stability is important to adaptive imaging ... Full text Link to item Cite

Comparison of recall and cancer detection rates for immediate versus batch interpretation of screening mammograms.

Journal Article Radiology · April 2005 PURPOSE: To retrospectively compare recall and cancer detection rates between immediate and subsequent batch methods for interpretation of screening mammograms. MATERIALS AND METHODS: Institutional review board approval was obtained, and informed consent w ... Full text Link to item Cite

BI-RADS for sonography: positive and negative predictive values of sonographic features.

Journal Article AJR Am J Roentgenol · April 2005 OBJECTIVE: The purpose of this study was to assess the positive predictive value (PPV) and negative predictive value (NPV) of features described in the new sonographic BI-RADS lexicon for evaluating solid masses with known histologic diagnoses. MATERIALS A ... Full text Link to item Cite

Computer-aided detection of amorphous calcifications.

Journal Article AJR Am J Roentgenol · March 2005 OBJECTIVE: Computer-aided detection (CAD) systems have been used successfully to detect malignant calcifications on mammography, with sensitivities ranging from 86% to 99%. Amorphous calcifications are a subset of small indistinct calcifications of interme ... Full text Link to item Cite

Detection of primary breast carcinoma with a dedicated, large-field-of-view FDG PET mammography device: initial experience.

Journal Article Radiology · February 2005 PURPOSE: To prospectively assess a dedicated, large field of view positron emission tomography (PET) mammographic device for imaging primary breast carcinoma. MATERIALS AND METHODS: Institutional review board approval was obtained for this study, and all p ... Full text Link to item Cite

Stereotactic breast biopsy of noncalcified lesions: a cost-minimization analysis comparing 14-gauge multipass automated core biopsy to 14- and 11-gauge vacuum-assisted biopsy.

Journal Article Clin Imaging · 2005 A decision model was used to compare the relative costs of the 14-gauge automated gun technique to the 14-gauge and 11-gauge vacuum-assisted techniques for stereotactic biopsy of noncalcified breast lesions. Probability and cost variables were estimated fr ... Full text Link to item Cite

Resolution improvement of point targets by real-time phase aberration correction: In vivo results

Journal Article Proceedings - IEEE Ultrasonics Symposium · December 1, 2004 Ten patients with suspected microcalcifications receiving treatment at the Duke University Medical Center were scanned with a 9MHz, 8x96 1.75D array transducer and Siemens Antares scanner. Aberration profiles were estimated by cross correlation of individu ... Cite

Spatial and temporal stability of tissue induced aberration

Journal Article Proceedings - IEEE Ultrasonics Symposium · December 1, 2004 Real-time adaptive imaging systems employ near-field phase correction techniques, which are desired because of their computational simplicity and compatibility with current imaging system architectures. Aberrator stability is essential to adaptive imaging ... Full text Cite

Acoustic radiation force impulse imaging of in vivo breast masses

Conference Proceedings - IEEE Ultrasonics Symposium · December 1, 2004 ARFI datasets were acquired in real time to identify differentiable features between benign and malignant breast masses in ARFI images. A modified Siemens SONOLINE Antares scanner and a VF10-5 probe were programmed to implement ARFI imaging in a multi-foca ... Cite

Clinical evaluation of combined spatial compounding and adaptive imaging in breast tissue.

Journal Article Ultrason Imaging · October 2004 When spatial compounding is applied to targets with significant acoustic velocity inhomogeneities, the correlation between speckle patterns of the images to be averaged decreases, thereby increasing the speckle reduction nominally obtained. Phase correctio ... Full text Link to item Cite

Imaging tissue mechanical properties using impulsive acoustic radiation force

Journal Article 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano · January 1, 2004 Acoustic Radiation Force Impulse (ARFI) imaging utilizes brief, high energy, focused acoustic pulses to generate radiation force in tissue, and conventional diagnostic ultrasound methods to detect the resulting tissue displacements in order to image the re ... Full text Cite

Accuracy of a collagen-plug biopsy site marking device deployed after stereotactic core needle breast biopsy.

Journal Article AJR Am J Roentgenol · November 2003 OBJECTIVE: The goal of this study was to compare the accuracy of clip placement of a collagen-plug biopsy marking device with that of the more conventional, previously evaluated metallic tissue-marking clips. SUBJECTS AND METHODS. The placement accuracy of ... Full text Link to item Cite

Accuracy of MRI in the detection of residual breast cancer after neoadjuvant chemotherapy.

Journal Article AJR Am J Roentgenol · November 2003 OBJECTIVE: This study was undertaken to evaluate the ability of MRI to accurately show residual primary breast malignancy in women treated with neoadjuvant chemotherapy. MATERIALS AND METHODS: Twenty-one patients with locally advanced primary breast carcin ... Full text Link to item Cite

Computer-aided detection (CAD) in screening mammography: sensitivity of commercial CAD systems for detecting architectural distortion.

Journal Article AJR Am J Roentgenol · October 2003 OBJECTIVE: Computer-aided detection (CAD) algorithms have successfully revealed breast masses and microcalcifications on screening mammography. The purpose of our study was to evaluate the sensitivity of commercially available CAD systems for revealing arc ... Full text Link to item Cite

Sonographic detection and sonographically guided biopsy of breast microcalcifications.

Journal Article AJR Am J Roentgenol · April 2003 OBJECTIVE: The purpose of this study was to evaluate the ability of sonography to depict and guide biopsies of mammographically suspicious microcalcifications and to reveal the mammographic features and histologic outcomes of lesions amenable to sonographi ... Full text Link to item Cite

Cortisol levels and responses to mammography screening in breast cancer survivors: a pilot study.

Journal Article Psychosom Med · 2003 OBJECTIVE: The purpose of this study was to compare baseline levels of salivary cortisol, diurnal cortisol slopes, and cortisol reactivity to a mammogram in breast cancer survivors and women without a history of cancer. METHODS: Participants were 33 breast ... Full text Link to item Cite

Imaging-guided core needle biopsy of papillary lesions of the breast.

Journal Article AJR Am J Roentgenol · November 2002 OBJECTIVE: Our objective was to assess the incidence of papillary lesions of the breast diagnosed at imaging-guided core needle biopsy and the need for surgical excision after a benign diagnosis. MATERIALS AND METHODS: This retrospective study included 137 ... Full text Link to item Cite

Interpretation of digital mammograms: comparison of speed and accuracy of soft-copy versus printed-film display.

Journal Article Radiology · May 2002 PURPOSE: To compare the speed and accuracy of the interpretations of digital mammograms by radiologists by using printed-film versus soft-copy display. MATERIALS AND METHODS: After being trained in interpretation of digital mammograms, eight radiologists i ... Full text Link to item Cite

Malignant lesions initially subjected to short-term mammographic follow-up.

Journal Article Radiology · April 2002 PURPOSE: To determine whether systematically evaluated criteria for probably benign lesions were actually applied to lesions placed into that category. MATERIALS AND METHODS: A search of the mammography database yielded 295 cases that were initially follow ... Full text Link to item Cite

Sonographically guided biopsy of suspicious microcalcifications of the breast: a pilot study.

Journal Article AJR Am J Roentgenol · April 2002 OBJECTIVE: The purpose of this study is to evaluate the use of sonographic guidance for biopsy of mammographically detected suspicious microcalcifications. SUBJECTS AND METHODS: Twenty-three patients with suspicious microcalcifications detected on mammogra ... Full text Link to item Cite

Breast US: assessment of technical quality and image interpretation.

Journal Article Radiology · April 2002 PURPOSE: To determine whether ultrasonography (US) of the breast performed at a wide range of clinical practices conforms to the American College of Radiology (ACR) standards for quality and to assess the interpretations of breast sonograms. MATERIALS AND ... Full text Link to item Cite

Acoustic radiation force impulse imaging: in vivo demonstration of clinical feasibility.

Journal Article Ultrasound Med Biol · February 2002 The clinical viability of a method of acoustic remote palpation, capable of imaging local variations in the mechanical properties of soft tissue using acoustic radiation force impulse (ARFI) imaging, is investigated in vivo. In this method, focused ultraso ... Full text Link to item Cite

MR imaging of extracapsular silicone from breast implants: diagnostic pitfalls.

Journal Article AJR Am J Roentgenol · February 2002 OBJECTIVE: We sought to identify pitfalls in recognition of extracapsular silicone on MR imaging. MATERIALS AND METHODS: Three experienced observers reviewed MR images from 359 women with current (n = 320), prior (n = 15), or both current and prior (n = 24 ... Full text Link to item Cite

Acoustic radiation force impulse imaging: Remote palpation of the mechanical properties of tissue

Journal Article Proceedings of the IEEE Ultrasonics Symposium · 2002 An overview is given of the Acoustic Radiation Force Impulse (ARFI) imaging. It discusses the derivation of radiation force, the response of tissue to radiation force, and the potential for this imaging method to evaluate the mechanical properties of tissu ... Cite

Negative predictive value of sonography with mammography in patients with palpable breast lesions.

Journal Article AJR Am J Roentgenol · November 2001 OBJECTIVE: This study was performed to determine the negative predictive value of sonography with mammography in evaluating palpable breast lesions. MATERIALS AND METHODS: Four hundred twenty patients with 455 palpable breast lesions were retrospectively i ... Full text Link to item Cite

Impact of core-needle breast biopsy on the surgical management of mammographic abnormalities.

Journal Article Ann Surg · June 2001 OBJECTIVE: To evaluate the accuracy of percutaneous, image-guided core-needle breast biopsy (CNBx) and to compare the surgical management of patients with breast cancer diagnosed by CNBx with patients diagnosed by surgical needle-localization biopsy (SNLBx ... Full text Link to item Cite

Silicone gel breast implant rupture, extracapsular silicone, and health status in a population of women.

Journal Article J Rheumatol · May 2001 OBJECTIVE: To assess whether breast implant rupture or extracapsular silicone are associated with selected symptoms of self-reported physician-diagnosed connective tissue disease (CTD). METHODS: Women with silicone gel breast implants responded to a questi ... Link to item Cite

Wavefront estimation in the human breast

Journal Article Proceedings of SPIE - The International Society for Optical Engineering · January 1, 2001 We acquired conventional and harmonic channel r.f. ultrasound echo data using a 3×80 element, 8.5 MHz multirow array from the breasts of eight volunteers. The data acquisition was interleaved to allow direct comparison normal and harmonic echo wavefronts. ... Full text Cite

In vivo breast tissue backscatter measurements with 7.5- and 10-MHz transducers.

Journal Article Ultrasound Med Biol · January 2001 Measurements of the ultrasound (US) backscatter coefficient (BSC) of fibroglandular and fatty breast tissues in vivo from 5.25 through 13 MHz, using the reference phantom method, are presented. Radiofrequency echo data were collected at a series of locatio ... Full text Link to item Cite

Investigation of real-time remote palpation imaging

Journal Article Proceedings of SPIE - The International Society for Optical Engineering · January 1, 2001 We are investigating a novel ultrasonic method for remote palpation, which provides images of local variations in tissue stiffness. Acoustic radiation force is applied to small volumes of tissue, and the resulting displacement patterns are imaged using ult ... Full text Cite

In vivo demonstration of acoustic radiation force impulse (ARFI) imaging in the thyroid, abdomen, and breast

Journal Article Proceedings of the IEEE Ultrasonics Symposium · 2001 Acoustic Radiation Force Impulse (ARFI) imaging is proposed as a method for characterizing local variations in tissue mechanical response. In this method, a single ultrasonic transducer array is used to both apply localized radiation forces within tissue a ... Cite

Tissue harmonic imaging sonography of breast lesions: improved margin analysis, conspicuity, and image quality compared to conventional ultrasound.

Journal Article Clin Imaging · 2001 The purpose of this preference study is to determine if tissue harmonic imaging (THI) is preferred over conventional sonography for imaging breast masses. A prospective evaluation of 73 identical image pairs (one obtained with conventional sonography, one ... Full text Link to item Cite

Prevalence of rupture of silicone gel breast implants revealed on MR imaging in a population of women in Birmingham, Alabama.

Journal Article AJR Am J Roentgenol · October 2000 OBJECTIVE: Silicone gel breast implants have been reported to rupture, but the prevalence of implant rupture in an unreferred population of women is not known. The objective of this study was to assess the prevalence of implant rupture and the presence of ... Full text Link to item Cite

The evolving role of sonography in evaluating solid breast masses.

Journal Article Semin Ultrasound CT MR · August 2000 Many investigators have attempted to use ultrasound imaging to differentiate benign from malignant solid breast masses. Studies have evaluated several generations of gray-scale imaging, Doppler, color Doppler, and power Doppler imaging, and several unconve ... Full text Link to item Cite

Tubular adenomas of the breast: imaging findings with histologic correlation.

Journal Article AJR Am J Roentgenol · March 2000 OBJECTIVE: The purpose of this study is to describe the imaging features of tubular adenomas, which are rare benign breast tumors usually found in women younger than 35 years old. CONCLUSION: In young women, tubular adenomas can look like noncalcified fibr ... Full text Link to item Cite

Optimizing visualization of breast microcalcifications

Journal Article Proceedings of the IEEE Ultrasonics Symposium · January 1, 2000 We combine our results from a series of clinical, experimental, and analytical studies to present comprehensive recommendations for the improved visualization of breast microcalcifications with ultrasound. Such improved visualization would extend the utili ... Full text Cite

Focal fibrosis: a common breast lesion diagnosed at imaging-guided core biopsy.

Journal Article AJR Am J Roentgenol · December 1999 OBJECTIVE: Focal fibrosis is a benign breast lesion commonly diagnosed by imaging-guided core biopsy. The goal of this study is to determine the frequency of focal fibrosis diagnosed at core biopsy and to describe its imaging features. MATERIALS AND METHOD ... Full text Link to item Cite

Adaptive imaging in the breast

Journal Article Proceedings of the IEEE Ultrasonics Symposium · December 1, 1999 Various adaptive imaging methods have been proposed to compensate for the image degradation caused by the non-uniform acoustic velocity in soft tissues. Most adaptive imaging methods employ measurements of echo arrival times at the receive array to modify ... Cite

In vivo breast tissue backscatter study with 7.5 MHz and 10 MHz probes

Journal Article Proceedings of the IEEE Ultrasonics Symposium · December 1, 1999 An on-going study of the backscatter coefficient (BSC) of fibroglandular breast tissue in vivo from 5-13 MHz is discussed. Initial results of the study are compared to published values for this tissue. The implications of these findings for the ultrasound ... Cite

Extended field-of-view two-dimensional ultrasonography of the breast: improvement in lesion documentation.

Journal Article J Ultrasound Med · September 1999 The purpose of this study was to evaluate the use of extended field-of-view two-dimensional ultrasonographic imaging for improvement in overall breast lesion documentation. Sonographic images of 59 patients with breast lesions or silicone implants were eva ... Full text Link to item Cite

Sonography of solid breast lesions: observer variability of lesion description and assessment.

Journal Article AJR Am J Roentgenol · June 1999 OBJECTIVE: The purpose of this study was to measure the level of inter- and intraobserver agreement and to evaluate the causes of variability in radiologists' descriptions and assessments of sonograms of solid breast masses. MATERIALS AND METHODS: Sixty so ... Full text Link to item Cite

Stereotactic biopsy of noncalcified breast lesions: utility of vacuum-assisted technique compared to multipass automated gun technique.

Journal Article Clin Imaging · 1999 The purpose of this study was to evaluate the stereotactic 14-gauge, vacuum-assisted biopsy technique in diagnosing noncalcified breast lesions. Stereotactic biopsy of 116 noncalcified breast lesions was performed with either 14-gauge, vacuum-assisted tech ... Full text Link to item Cite

An in vivo breast tissue backscatter study with 7.5 MHz and 10 MHz probes

Conference 1999 IEEE ULTRASONICS SYMPOSIUM PROCEEDINGS, VOLS 1 AND 2 · 1999 Cite

Application of sound speed estimation and mapping to multi-layer media and in vivo data

Journal Article Proceedings of the IEEE Ultrasonics Symposium · December 1, 1998 The application of a pulse-echo sound speed estimation technique to multi-layered and biological media is discussed and demonstrated in simulation, phantom, and clinical experiments. We have recently described and demonstrated a technique which estimates t ... Cite

Imaging-guided core biopsies in the breast.

Journal Article South Med J · November 1998 Screening mammography programs have contributed to an overall decline in breast cancer mortality. The screening process, however, also results in detection and biopsy of many nonpalpable lesions that eventually prove to be benign, contributing to the burde ... Full text Link to item Cite

Microcalcifications as elastic scatterers under ultrasound.

Journal Article IEEE Trans Ultrason Ferroelectr Freq Control · 1998 One of the fundamental limitations of medical ultrasound in the imaging of the breast is the inability of current practice to reliably visualize microcalcifications in the size range of clinical interest. Microcalcifications (MCs) are small crystals of cal ... Full text Link to item Cite

Fat necrosis in the breast: sonographic features.

Journal Article Radiology · January 1998 PURPOSE: To evaluate the ultrasonographic (US) features and evolution of fat necrosis in the breast. MATERIALS AND METHODS: The US features of 31 breast masses in 23 patients were reviewed. Fat necrosis was diagnosed on the basis of histologic (n = 20) and ... Full text Link to item Cite

Wavefront distortion measurements in the human breast

Journal Article Proceedings of the IEEE Ultrasonics Symposium · December 1, 1997 Published wavefront distortion (phase aberration) measurements for the human breast ranged from mild phase aberrations (8 ns r.m.s) to severe phase aberrations (67 ns r.m.s.). These measurements are required to specify arrays and assess the potentials of a ... Cite

Breast tumour imaging using incomplete circular orbit pinhole SPET: a phantom study.

Journal Article Nucl Med Commun · November 1997 Improvements in 99Tcm-sestamibi breast lesion visualization using single photon emission tomography (SPET) may help define the clinical role of this technique alongside X-ray mammography in the diagnosis and management of breast cancer. Pinhole SPET offers ... Full text Link to item Cite

The detection of breast microcalcifications with medical ultrasound.

Journal Article J Acoust Soc Am · January 1997 Microcalcifications are small crystals of calcium apatites which form in human tissue through a number of mechanisms. The size, morphology, and distribution of microcalcifications are important indicators in the mammographic screening for and diagnosis of ... Full text Link to item Cite

Intracapsular implant rupture: MR findings of incomplete shell collapse.

Journal Article J Magn Reson Imaging · 1997 The objective of this study was to determine the frequency and significance of the MR findings of incomplete shell collapse for detecting implant rupture in a series of surgically removed breast prostheses. MR images of 86 breast implants in 44 patients we ... Full text Link to item Cite

Axillary lymph nodes: mammographic, pathologic, and clinical correlation.

Journal Article AJR Am J Roentgenol · January 1997 OBJECTIVE: The purpose of this study was to determine the cause and frequency of axillary abnormalities seen mammographically and to evaluate the imaging characteristics of lymphadenopathy that are associated with malignancy. MATERIALS AND METHODS: Ninety- ... Full text Link to item Cite

MR imaging of the breast

Journal Article Applied Radiology · December 1, 1996 Cite

Complex radial folds versus subtle signs of intracapsular rupture of breast implants: MR findings with surgical correlation.

Journal Article AJR Am J Roentgenol · June 1996 Detection of intracapsular rupture of silicone breast prostheses using MR imaging is often performed by identifying the "linguine sign" [1]. The linguine sign is easily differentiated from simple radial folds that are seen in intact implants. However, more ... Full text Link to item Cite

Film screen mammography and sonography in the evaluation of breast prosthesis integrity

Journal Article Breast Disease · March 1, 1996 The purpose of this study was to determine the sensitivity and specificity of film screen mammography and sonography in detecting implant rupture and identify findings significantly associated with rupture, The sensitivity and specificity of preoperative m ... Cite

Microcalcifications as elastic scatterers under ultrasound: implications for medical imaging

Journal Article Proceedings of the IEEE Ultrasonics Symposium · 1996 Microcalcifications are small crystals of calcium phosphates which form in human tissue through a number of mechanisms. The size, morphology, and distribution of microcalcifications (MCs) are important indicators in the mammographic screening for and diagn ... Cite

Computer aided prediction of breast implant rupture based on mammographic findings

Conference Proceedings of SPIE - The International Society for Optical Engineering · May 12, 1995 A computer aided diagnostic system has been developed to predict the status of a breast implant (intact/ruptured) based on mammographic findings. Mammograms were obtained from 112 patients who presented for surgical removal of breast implants. Findings wer ... Full text Cite

Seromas in residual fibrous capsules after explantation: mammographic and sonographic appearances.

Journal Article Radiology · March 1995 PURPOSE: To evaluate the mammographic and sonographic findings associated with seromas that develop in residual fibrous capsules after explantation of breast prostheses. MATERIALS AND METHODS: Preoperative and postoperative mammograms were reviewed in 86 p ... Full text Link to item Cite

Papillary carcinoma of the breast: imaging findings.

Journal Article AJR Am J Roentgenol · February 1995 Papillary carcinoma is a rare malignant tumor of the breast for which the survival rate is better than for most breast carcinomas. Histologically, invasive and in situ forms occur; the in situ form can extend throughout a ductal system (intraductal) or can ... Full text Link to item Cite

Periprosthetic mycobacterial infection. CT and mammographic findings.

Journal Article Clin Imaging · 1995 Organisms of the Mycobacterium fortuitum complex are an uncommon but important cause of periprosthetic infection following augmentation mammoplasty or other breast surgery. This etiological agent must be considered in the particular case of periprosthetic ... Full text Link to item Cite

Evaluation of the ultrasonic detectability of microcalcifications

Journal Article Proceedings of the IEEE Ultrasonics Symposium · 1995 Microcalcifications are small crystals of calcium apatites which form in human tissue through a number of mechanisms. The size, morphology, and distribution of microcalcifications are important indicators in the mammographic screening for and diagnosis of ... Cite

Seromas in the breast: imaging findings.

Journal Article Crit Rev Diagn Imaging · 1995 Breast seromas are tumor-like collections of serosanguineous fluid in breast tissue that occur following excisional biopsy, lumpectomy, mastectomy, and plastic surgery procedures such as augmentation, prosthesis explantation, breast reduction, and breast r ... Link to item Cite

Management of pineal non-germinoma germ cell tumor with residual teratoma and normal alpha-fetoprotein.

Journal Article Med Pediatr Oncol · 1994 A 16-year-old white male presented with multiple abnormal extraocular movements secondary to an enhancing pineal tumor. Subtotal resection of the lesion revealed a mixed malignant germ cell tumor. The preoperative serum alpha-fetoprotein (AFP) was markedly ... Full text Link to item Cite

Mesenrhombencephalitis: MR findings in nine patients.

Journal Article AJR Am J Roentgenol · May 1993 OBJECTIVE: Mesenrhombencephalitis is a serious form of brainstem inflammation predominantly involving the deep and vital portions of the brain, that is, the mesencephalon (midbrain) and rhombencephalon (pons, medulla). Mesenrhombencephalitis is difficult t ... Full text Link to item Cite

Splenic vein aneurysm: MR appearance--a case report.

Journal Article Angiology · July 1991 A presumed pancreatic head mass by non-contrast CT examination, was proven to be a splenic vein aneurysm by enhanced CT, MRI, sonography and arteriography. Dangerous percutaneous aspiration was avoided. ... Full text Link to item Cite

Degenerative disease of the lumbar spine. Role of CT-myelography in the MR era.

Journal Article Clin Imaging · 1991 One hundred patients with degenerative disease of the lumbar spine on whom both magnetic resonance (MR) and computed tomography (CT)-myelography were performed were reviewed. In one-third of the cases, the CT-myelogram provided additional useful informatio ... Full text Link to item Cite

Metastatic lesions arising in a Riedel's lobe. Findings from a sulfur colloid liver-spleen scan.

Journal Article Clin Nucl Med · November 1990 Clinically significant lesions originating within a Riedel's lobe are extremely rare. Characteristic findings from a Tc-99m SC liver-spleen scan of metastatic breast carcinoma arising in a Riedel's lobe are described. ... Full text Link to item Cite

Intra-aortic counterpulsation balloon pumps: CT appearance.

Journal Article Clin Imaging · August 1990 Intra-aortic counterpulsation balloon pumps (ICBP) used in the setting of cardiogenic shock or high risk cardiac surgery, have been identified on chest films in the inflated state during diastole (1). We report characteristic computed tomography (CT) findi ... Full text Link to item Cite