Scholars@Duke
Erica Sopah Peethumnongsin

Erica Sopah Peethumnongsin

Assistant Professor of Emergency Medicine
Emergency Medicine

Selected Publications

Co-designed point-of-care ultrasound program development and implementation at a Veterans Affairs emergency department.

Journal Article Intern Emerg Med · April 25, 2025 Integrating point-of-care ultrasound (POCUS) into patient care requires a multifaceted culture change using a multi-pronged approach. A standardized implementation method is lacking for POCUS program sustainability. We developed a standardized training cur ... Full text Link to item Cite

Accuracy and Feasibility of Three-Dimensional Ultrasound Testing in Eye Clinic and Emergency Department Patients with Vision Complaints.

Journal Article J Emerg Med · February 2024 BACKGROUND: Ocular emergencies comprise 2-3% of emergency department (ED) visits, with retinal detachment requiring emergency surgery. Two-dimensional ultrasound is a rapid bedside tool but is highly operator dependent. OBJECTIVE: We determined three-dimen ... Full text Link to item Cite

Velocity changes in femoral vessel ultrasound with Doppler in Porcine hemorrhagic shock.

Journal Article Heliyon · January 15, 2024 OBJECTIVE: Physician-directed point-of-care ultrasound (PoCUS) is routinely used to identify the etiology of shock and guide therapy in the ICU. We performed a preclinical study to determine what changes are manifested in the femoral vessels during hemorrh ... Full text Link to item Cite

Molar pregnancy presenting with vaginal bleeding in an emergency department patient

Journal Article Visual Journal of Emergency Medicine · January 1, 2022 Full text Cite

FEMORAL VESSEL DUPLEX IN A SWINE MODEL OF HEMORRHAGIC SHOCK

Conference CRITICAL CARE MEDICINE · 2022 Cite

Infant With Abdominal Fullness.

Journal Article Ann Emerg Med · May 2020 Full text Open Access Link to item Cite

Perinephric hematoma visualized on bedside ultrasound in the emergency department

Journal Article Visual Journal of Emergency Medicine · October 1, 2018 Full text Cite

Evaluation of Transplant Kidneys Using a Novel Point of Care 3D Ultrasound System.

Conference AMERICAN JOURNAL OF TRANSPLANTATION · June 1, 2018 Link to item Cite

394 Brain Imaging Using a Novel Three-Dimensional Ultrasound System

Conference Annals of Emergency Medicine · October 2017 Full text Cite

Systematic review and meta-analysis of the accuracy of MRI to diagnose appendicitis in the general population.

Journal Article J Magn Reson Imaging · June 2016 PURPOSE: To perform a systematic review and meta-analysis of all published studies since 2005 that evaluate the accuracy of magnetic resonance imaging (MRI) for the diagnosis of acute appendicitis in the general population presenting to emergency departmen ... Full text Link to item Cite

Convergence of presenilin- and tau-mediated pathways on axonal trafficking and neuronal function.

Journal Article J Neurosci · October 6, 2010 Alzheimer's disease (AD) is a significant and growing health problem in the aging population. Although definitive mechanisms of pathogenesis remain elusive, genetic and histological clues have implicated the proteins presenilin (PS) and tau as key players ... Full text Link to item Cite

Increased Human Wildtype Tau Attenuates Axonal Transport Deficits Caused by Loss of APP in Mouse Models.

Journal Article Magn Reson Insights · 2010 Amyloid precursor protein (APP) is implicated in axonal elongation, synaptic plasticity, and axonal transport. However, the role of APP on axonal transport in conjunction with the microtubule associated protein tau continues to be debated. Here we measured ... Full text Link to item Cite

Pen2 and presenilin-1 modulate the dynamic equilibrium of presenilin-1 and presenilin-2 gamma-secretase complexes.

Journal Article J Biol Chem · January 30, 2009 gamma-Secretase is known to play a pivotal role in the pathogenesis of Alzheimer disease through production of amyloidogenic Abeta42 peptides. Early onset familial Alzheimer disease mutations in presenilin (PS), the catalytic core of gamma-secretase, invar ... Full text Link to item Cite

Role of the amyloid precursor protein in tau modulation

Conference JOURNAL OF NEUROCHEMISTRY · August 1, 2007 Link to item Cite

Lack of alpha-synuclein increases amyloid plaque accumulation in a transgenic mouse model of Alzheimer's disease.

Journal Article Mol Neurodegener · March 16, 2007 Alpha-synuclein is a small soluble, cytosolic protein which associates with vesicular membranes. It is a component of intracellular Lewy bodies present in Parkinson's disease and a subset of Alzheimer's disease (AD). In addition, early studies identified a ... Full text Link to item Cite

Deletion of presenilin 1 hydrophilic loop sequence leads to impaired gamma-secretase activity and exacerbated amyloid pathology.

Journal Article J Neurosci · April 5, 2006 gamma-Secretase processing of the amyloid precursor protein (APP) generates Abeta40 and Abeta42, peptides that constitute the principal components of the beta-amyloid plaque pathology of Alzheimer's disease (AD). The gamma-secretase activity is executed by ... Full text Link to item Cite