Sven Eric Jordt

Voting Member - Tobacco Products Scientific Advisory Committee (TPSAC) · April 23, 2023 Consulting US Food and Drug Administration (FDA) , Washington, DC flag

United States of America The Tobacco Products Scientific Advisory Committee (TPSAC) reviews and evaluates safety, dependence, and health issues relating to tobacco products and provides appropriate advice, information and recommendations to the Commissioner of Food and Drugs.

Scientific Advisor - Eleventh Meeting of the World Health Organization (WHO) Study Group on Tobacco Product Regulation (TobReg) · December 13, 2022 Consulting World Health Organization (WHO) , Tbilisi, Georgia The eleventh meeting of the WHO Study Group on Tobacco Product Regulation (TobReg) provided a forum for scientists to deliberate on and update knowledge on pertinent issues related to the regulation of nicotine and tobacco products. The meeting focused specifically on emerging issues, such as the use of synthetic nicotine in nicotine and tobacco products and nicotine pouches and other topics based on requests to the Conference of Parties (COP) to the WHO Framework Convention on Tobacco Control (WHO FCTC) at various sessions. The following background papers informed the meeting: Additives that facilitate inhalation, including cooling agents, nicotine salts and flavourings. Synthetic nicotine: science, global legal landscape and regulatory considerations. Nicotine pouches: characteristics, use, harmfulness and regulation. Biomarkers of exposure, effect and susceptibility for assessing electronic nicotine delivery devices and heated tobacco products, and their possible prioritization. Internet, influencer and social media marketing of tobacco and nontherapeutic nicotine products and associated regulatory considerations. The WHO Study Group on Tobacco Product Regulation: two decades of recommendations – translating evidence into policy action. It was a closed working group meeting for WHO TobReg members, WHO staff, the Secretariat of the WHO FCTC and invited experts. The resulting TobReg recommendations were compiled into the 9th technical report series (TRS) of the study group, which were presented to the WHO Executive Board at its 153rd session. The recommendations of the report, will guide Member States in achieving the most effective and evidence-based means to bridge regulatory gaps in tobacco control, develop coordinated regulatory framework for tobacco products, guide international policy and provide access to scientific information. The eleventh meeting of TobReg took place in Tbilisi, Georgia from 13 - 15 December 2022 and was generously hosted by the Georgian National Centre for Disease Control and Public Health and organized by the WHO.

Scientific Advisor - Technical Workshop on Novel and Emerging Nicotine and Tobacco Products Experiences · June 23, 2022 Consulting World Health Organization (WHO) & European Union (EU) , Copenhagen Novel nicotine and tobacco products such as e-cigarettes and heated tobacco products are gaining popularity worldwide, especially among adolescents and young adults. The diversity of the products, their design features and characteristics, makes it hard for countries to regulate them and monitor their use in the population. The WHO Regional Office for Europe, in collaboration with WHO Headquarters and the European Commission, is organizing a technical workshop to provide a platform for information exchange and direct engagement with experts. It also aims to contribute to building capacity of EU Member States to effectively regulate these products, and those protecting young people from tobacco and nicotine addiction. The event will convene tobacco control focal points from the Member States of the European Union, as well as invited experts from the European Commission, WHO and WHO FCTC Secretariat. The workshop’s discussions will include the following topics: Latest data: science and marketing of novel nicotine and tobacco products Challenges, achievements and regulatory needs of the European Union in relation to these products What further support is needed from WHO and the European Commission in addressing the challenges related to novel nicotine and tobacco products?

Expert - Gobal Health NOW · June 16, 2020 Community Outreach Johns Hopkins Bloomberg School of Public Health Is the use of tear gas or pepper spray during the COVID-19 pandemic extra dangerous? How can people protect themselves?

Service to the Profession

Grant Application Reviewer - Progress Review Meeting · July 2, 2019 - July 4, 2019 Committee Service Science Foundation Ireland (SFI), Dublin Central University

NIH Grant Application Reviewer - ZRG1 BST-T (55) R RFA Panel: Tobacco Regulatory Biomedical Science - Basic · May 30, 2019 Committee Service National Institutes of Health (NIH) - Center for Scientific Review (CSR), Online

Moderator, Minisymposium - Chemical threats and injury: mechanisms and treatment · May 19, 2019 Event/Organization Administration American Thoracic Society, Dallas, TX

Co-Chair, Basic Science Network (BSN) · May 2019 Committee Service Society for Research on Nicotine and Tobacco (SRNT),

The Basic Science Network (BSN) of the Society for Research on Nicotine and Tobacco (SRNT) provides an outlet for SRNT members undertaking basic science research to network with one another; to provide guidance to the SRNT Board and committees as necessary to better inform programs and/or discussions that address basic science; to help SRNT advance the field of basic science research globally.

NIH Grant Application Reviewer - ZAT1 AJT 10 - NCCIH Training and Education Review Panel (CT) Review Panel · March 27, 2019 Committee Service National Institutes of Health (NIH) - National Center for Complementary and Integrative Health (NCCIH), Teleconference

NIH Grant Application Reviewer - NIH-CSR-RES SEP-ZRG1 CVRS-H: R21 and R01 applications on Electronic Nicotine Delivery Systems: Basic Mechanisms of Health Effects. · March 22, 2019 - March 23, 2019 Committee Service National Institutes of Health (NIH) - Center for Scientific Review (CSR), Teleconference

NIH Grant Application Reviewer - 2018 ZRG1-CVRS-N(03): R21 and R01 applications on Electronic Nicotine Delivery Systems: Basic Mechanisms of Health Effects · December 4, 2018 - December 5, 2018 Committee Service National Institutes of Health (NIH) - Center for Scientific Review (CSR), Teleconference

NIH Grant Application Reviewer - ZRG1 MDCN-B(55) Countermeasures Against Chemical Threats Special Emphasis Panel, Baltimore, MD · June 21, 2018 Committee Service National Institutes of Health (NIH) - Center for Scientific Review (CSR), Baltimore, MD

Ad hoc reviewer · 2018 Editorial Activities JCI Insight

Consultant · 2018 Consulting Sanofi, Cambridge, MA

Neurobiology of thermal sensing, thermoreceptors.

Chair, Section on Terrorism and Inhalation Disasters (TID) · May 2017 - May 2019 Committee Service American Thoracic Society,

The Section on Terrorism and Inhalation Disasters (TID) of the American Thoracic Society (ATS) is a multidisciplinary group of individuals who share a common interest in disaster preparedness, response and research. The major goals of this section are to advance of current research efforts to improve our understanding of the pathophysiology and management of inhalational injuries, severe outbreaks of infectious disease and their impact on respiratory and critical care management, and to maximize disaster preparedness within the medical community.

NIH Grant Application Reviewer - ZRG1 MDCN-B(55) Countermeasures Against Chemical Threats Special Emphasis Panel, Baltimore, MD · July 8, 2016 Committee Service National Institutes of Health (NIH) - Center for Scientific Review (CSR), Baltimore, MD

Associate Editor · 2016 Editorial Activities Tobacco Regulatory Science,

Tobacco Regulatory Science (Electronic ISSN 2333-9748) is a rigorously peer-reviewed online scientific journal for the dissemination of research relevant to the regulation of tobacco products. The journal content includes a broad array of research domains, including chemistry, biology, behavior, community, and population-level surveillance and epidemiology, as well as knowledge syntheses (eg, meta-analyses or state-of-the-art reviews) and analytic modeling. All articles describe the policy relevance of the research outcomes. Given the global nature of tobacco regulation, particularly as a result of international and national policies, Tobacco Regulatory Science publishes high quality research that is relevant to global regulatory needs and requirements. Tobacco Regulatory Science is published electronically 6 times per year.

Program Committee Member, Assembly on Environmental, Occupational and Public Health (EOPH) · 2016 Committee Service American Thoracic Society,

The EOPH Assembly represents a broad range of clinicians, researchers, educators, and public health professionals who are interested in the contribution of environmental or occupational factors to the burden of lung disease.

NIH Grant Application Reviewer - ZRG1 MDCN-B(55) Countermeasures Against Chemical Threats Special Emphasis Panel, Baltimore, MD · July 16, 2015 Committee Service National Institutes of Health (NIH) - Center for Scientific Review (CSR), Baltimore, MD

Planning Committee Member, Assembly on Environmental, Occupational and Public Health (EOPH) · 2015 - 2016 Committee Service American Thoracic Society,

NIH Grant Application Reviewer - ZRG1 MDCN-B(55) Countermeasures Against Chemical Threats Special Emphasis Panel, Baltimore, MD · July 11, 2014 Committee Service National Institutes of Health (NIH) - Center for Scientific Review (CSR), Washington, DC

NIH Grant Application Reviewer - ZRG1 MDCN-B(55) Countermeasures Against Chemical Threats Special Emphasis Panel, Baltimore, MD · June 4, 2013 Committee Service National Institutes of Health (NIH) - Center for Scientific Review (CSR), Washington, DC

NIH Grant Application Reviewer - ZRG1 MDCN-J54 / J50 CounterACT special emphasis panel · March 19, 2013 Committee Service National Institutes of Health (NIH) - Center for Scientific Review (CSR), Washington, DC

NIH Grant Application Reviewer - ZDC1 SRB-R (39). Clinical Research Center Grants (P50), FDA-sponsored tobacco regulatory research · January 31, 2013 Committee Service National Institutes of Health (NIH) - Center for Scientific Review (CSR), Internet Assisted Review

NIH Grant Application Reviewer - NIH Intramural Center for Tobacco Regulatory Science · October 22, 2012 Committee Service National Institutes of Health (NIH) , Internet Assisted Review

NIH Grant Application Reviewer - ZAT1 SM (25), NCCAM, Asthma mechanisms · July 19, 2012 - July 20, 2012 Committee Service National Institutes of Health (NIH) - Center for Scientific Review (CSR), Internet Assisted Review

NIH Grant Application Reviewer - ZRG1-IFCN-B-02M , R01 applications on sensory biology · June 1, 2011 - June 2, 2011 Committee Service National Institutes of Health (NIH) - Center for Scientific Review (CSR), Internet Assisted Review

NIH Grant Application Reviewer - MDCN J54 / J50, Countermeasures Against Chemical Threats Special Emphasis Panel · March 22, 2011 Committee Service National Institutes of Health (NIH) - Center for Scientific Review (CSR), Alexandria, MD

NIH Grant Application Reviewer - ZRG1-IFCN-B-51,R01 applications in sensory biology · February 22, 2011 - February 23, 2011 Committee Service National Institutes of Health (NIH) - Center for Scientific Review (CSR), Internet Assisted Review

Consultant · 2011 Consulting Boehringer Ingelheim, Biberach, Germany

Consulting on pharmacology and neurobiology of asthma.

Consulting · 2011 Consulting Abbott Laboratories, Chicago, IL

TRP ion channel pharmacology, pain neurobiology.

Consultant · 2011 Consulting Cubist Pharmaceuticals, Lexington, MA

Consulting on pain pharmacology.

NIH Grant Application Reviewer - ZRG1-IFCN-B-03M, R01 applications in sensory biology · September 29, 2010 - September 30, 2010 Committee Service National Institutes of Health (NIH) - Center for Scientific Review (CSR), Internet Assisted Review

Consultant · 2009 Consulting Ono Pharmaceuticals, Japan,

Consulting on function of bioactive lipids (cannabinoids, prostaglandins etc.) in inflammation and pain.

NIH Grant Application Reviewer - ZRG1-F02B-Y-20L, NRSA Fellowship Applications · 2009 Committee Service National Institutes of Health (NIH) - Center for Scientific Review (CSR),

Consultant - Research Planning Workshop · 2008 Consulting Health Effects Institute, Boston, MA

Consulting on TRP ion channels as new targets of air pollution and airborne irritants.

Consultant · 2008 Consulting Forrest Laboratories, LLC, Jersey City, NJ

Consulting on pain pharmacology, TRP ion channel targets.

Ad hoc reviewer · 2008 Editorial Activities Journal of Clinical Investigation (JCI),

Member, Scientific Advisory Board · 2006 - 2018 Consulting Hydra Biosciences Inc., Cambridge, MA

Hydra Biosciences, Inc., a biopharmaceutical company, developed novel drugs to treat pain, inflammation, renal, anxiety, pulmonary, and other diseases using novel ion channels as targets, specifically, members of the Transient Receptor Potential (TRP) family of ion channels. The company was founded in 2001 in Cambridge, Massachusetts.

Service to Duke

Appointments, Promotion and Tenure Committee (APT) (Department) · 2018 Committee Service Department of Anesthesiology,

Reviewer . Bridge Funding Program · 2016 Other Duke University School of Medicine,