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Teresa Kathleen Tarrant

Associate Professor of Medicine
Medicine, Rheumatology and Immunology
200 Trent Dr., DUMC 3874, Durham, NC 27710
235 Sands Resarch Bldg, 303 Research Dr., Durham, NC 27710

Overview


I first became interested in clinical immunology as a medical student studying autoimmune inflammatory eye disease at the National Institutes of Health.  Since then, I have been inspired to understand what causes autoimmunity and immune deficiency disorders in order to improve the quality of life for my patients.  I see patients with multiple complex immune disorders with particular expertise in autoimmune and Rheumatoid arthritis, primary Sjogren's syndrome, and the immunodeficiency disorders Common Variable Immunodeficiency (CVID), Adenosine Deaminase Deficiency (ADA) disorders, and WHIM (Warts, Hypogammaglobulinemia, Infections, and Myelokathexis). My research investigates immune targets that may impact either the development of immune disease or identify new therapies for patients.  The goal is to help us understand why and how immunologic diseases develop so that we may better treat them.

Current Duke Appointments & Affiliations


Associate Professor of Medicine · 2018 - Present Medicine, Rheumatology and Immunology, Medicine

Recent News Items


Published November 30, 2022
Biospace
After a Tough Summer, X4 Celebrates Phase III Win in WHIM Syndrome
Published December 8, 2020
Three I&E Incubation Awards Fund Novel Ideas to Solar Energy, IBD & Medical Laser Research
Published July 14, 2020
Accuracy in Rheumatoid Arthritis Testing Can Improve Diagnosis, Lower Costs

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Recent Scholarly Works


ADA2 genotype and enzyme activity may predict vasculitic or hematologic DADA2 phenotype.

Journal article J Hum Immun · September 7, 2026 Deficiency of adenosine deaminase 2 (DADA2) is an autoinflammatory disease with diverse phenotypes. We describe the genetics, phenotypes, and treatment of n = 48 DADA2 patients from Germany, Austria, and Switzerland. We report a high incidence of hematolog ... Full text Link to item Cite

A case of progressive multifocal leukoencephalopathy in an adult patient with ADA-SCID.

Journal article J Hum Immun · September 7, 2026 This case report describes progressive multifocal leukoencephalopathy in a patient with ADA-SCID status after gene therapy. Persistent metabolic dysfunction likely contributed to JC virus reactivation, highlighting this rare complication of ADA-SCID and in ... Full text Link to item Cite
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Education


University of Florida, College of Medicine · 1999 M.D.