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Teresa Kathleen Tarrant

Associate Professor of Medicine
Medicine, Rheumatology and Immunology
200 Trent Dr., DUMC 3874, Durham, NC 27710
235 Sands Resarch Bldg, 303 Research Dr., Durham, NC 27710

Overview


I first became interested in clinical immunology as a medical student studying autoimmune inflammatory eye disease at the National Institutes of Health.  Since then, I have been inspired to understand what causes autoimmunity and immune deficiency disorders in order to improve the quality of life for my patients.  I see patients with multiple complex immune disorders with particular expertise in autoimmune and Rheumatoid arthritis, primary Sjogren's syndrome, and the immunodeficiency disorders Common Variable Immunodeficiency (CVID), Adenosine Deaminase Deficiency (ADA) disorders, and WHIM (Warts, Hypogammaglobulinemia, Infections, and Myelokathexis). My research investigates immune targets that may impact either the development of immune disease or identify new therapies for patients.  The goal is to help us understand why and how immunologic diseases develop so that we may better treat them.

Current Appointments & Affiliations


Associate Professor of Medicine · 2018 - Present Medicine, Rheumatology and Immunology, Medicine

In the News


Published November 30, 2022
After a Tough Summer, X4 Celebrates Phase III Win in WHIM Syndrome
Published December 8, 2020
Three I&E Incubation Awards Fund Novel Ideas to Solar Energy, IBD & Medical Laser Research
Published July 14, 2020
Accuracy in Rheumatoid Arthritis Testing Can Improve Diagnosis, Lower Costs

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Recent Publications


Evolving spectrum of adenosine deaminase (ADA) deficiency: Assessing genotype pathogenicity according to expressed ADA activity of 46 variants.

Journal Article J Allergy Clin Immunol · January 2025 BACKGROUND: Deficiency of adenosine deaminase (ADA or ADA1) has broad clinical and genetic heterogeneity. Screening techniques can identify asymptomatic infants whose phenotype and prognosis are indeterminate, and who may carry ADA variants of unknown sign ... Full text Link to item Cite

Purine Nucleoside Phosphorylase Deficiency Presenting with Neurological Involvement: A Case Report of Two Siblings

Journal Article Asthma Allergy Immunology · August 1, 2024 Purine nucleoside phosphorylase (PNP) deficiency is a rare immunodeficiency syndrome generally characterized by profound T cell deficiency and variable B cell function. More than half of PNP-deficient patients present with neurological dysfunction, with ma ... Full text Cite
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Education, Training & Certifications


University of Florida, College of Medicine · 1999 M.D.