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Thomas Michael Price

Professor Emeritus of Obstetrics and Gynecology
Obstetrics and Gynecology, Reproductive Endocrinology & Infertility
Box 3143 Med Ctr, Durham, NC 27710
Duke Fertility Clinic, 5601 Arringdon Park Dr., Ste 210, Morrisville, NC 27560
Office hours M-F 8 am - 5 pm  

Overview


Dr. Price is involved in both clinical and basic science research. The main focus of the basic science molecular endocrinology laboratory is the study of novel sex steroid receptors. Currently, the work focuses on a novel progesterone receptor that localizes to the mitochondrion. Studies including RNAi in cell models and creation of transgenic mice are ongoing to discover the function of this receptor. The overall hypothesis is that progesterone modulates mitochondrial activity to meet the increased cellular energy demands of pregnancy via this receptor.
Dr. Price also participates in clinical research endeavors. These projects are constantly changing and focus on many aspects of reproductive endocrinology including ovarian preservation during chemotherapy, treatments for menorrhagia, endometriosis, leiomyomata and infertility.

Current Appointments & Affiliations


Professor Emeritus of Obstetrics and Gynecology · 2023 - Present Obstetrics and Gynecology, Reproductive Endocrinology & Infertility, Obstetrics and Gynecology

Recent Publications


Early postpartum blood pressure screening is associated with increased detection of cardiovascular risk factors in women with hypertensive disorders of pregnancy.

Journal Article Am Heart J · July 2024 BACKGROUND: Hypertensive disorders of pregnancy (HDP), including gestational hypertension, preeclampsia, and eclampsia, are risk factors for cardiovascular (CV) disease. Guidelines recommend that women with HDP be screened for the development of hypertensi ... Full text Link to item Cite

Differential Gene Regulation of the Human Blastocyst Trophectoderm and Inner Cell Mass by Progesterone.

Journal Article Reprod Sci · May 2024 Knowledge of action of progesterone (P4) on the human preimplantation embryo is lacking. The objective of this study was to determine expression of a mitochondrial P4 receptor (PR-M) in the trophectoderm (TE) and the inner cell mass (ICM) of the human blas ... Full text Link to item Cite

Perception of gender disparity in academic reproductive endocrinology and infertility.

Conference Hum Fertil (Camb) · December 2023 The aim of this study was to identify gender differences in leadership/academic rank and attitudes regarding gender representation among academic Reproductive Endocrinology and Infertility subspecialists. Members of the Society of Reproductive Endocrinolog ... Full text Link to item Cite
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Recent Grants


The role of progesterone in preimplantation human embryo metabolism

ResearchPrincipal Investigator · Awarded by Foundation For The Assessment and Enhancement of Embryonic Competence · 2019 - 2022

Paternal Transgenerational Epigenetic Legacy from Use of Cannabis

ResearchCo Investigator · Awarded by John Templeton Foundation · 2017 - 2022

ExAblate Registry

ResearchPrincipal Investigator · Awarded by Insightec · 2015 - 2020

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Education, Training & Certifications


University of North Carolina, Chapel Hill · 1984 M.D.