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Thomas Michael Price

Professor Emeritus of Obstetrics and Gynecology
Obstetrics and Gynecology, Reproductive Endocrinology & Fertility
Box 3143 Med Ctr, Durham, NC 27710
Duke Fertility Clinic, 5601 Arringdon Park Dr., Ste 210, Morrisville, NC 27560
Office hours M-F 8 am - 5 pm  

Research Interests


Mitochondrial progesterone receptor
T-type calcium channel function in myometrium
Chronic endometritis and fertility
Progesterone effect on the human embryo transcriptome and metabolome

Selected Grants


The role of progesterone in preimplantation human embryo metabolism

ResearchPrincipal Investigator · Awarded by Foundation For The Assessment and Enhancement of Embryonic Competence · 2019 - 2022

Paternal Transgenerational Epigenetic Legacy from Use of Cannabis

ResearchCo Investigator · Awarded by John Templeton Foundation · 2017 - 2022

ExAblate Registry

ResearchPrincipal Investigator · Awarded by Insightec · 2015 - 2020

Treatment of Uterine Fibroids by ExAblate MR guided FUS- Long Term Followup

ResearchPrincipal Investigator · Awarded by Insightec · 2015 - 2020

The Impact of Chronic Endometritis on IVF Pregnancy and Miscarriage Rates

ResearchPrincipal Investigator · Awarded by Vivere Heatlh LLC · 2015 - 2019

The role of progesterone in preimplantation human embryo metabolism

ResearchPrincipal Investigator · Awarded by Foundation For The Assessment and Enhancement of Embryonic Competence · 2019 - 2022

Paternal Transgenerational Epigenetic Legacy from Use of Cannabis

ResearchCo Investigator · Awarded by John Templeton Foundation · 2017 - 2022

ExAblate Registry

ResearchPrincipal Investigator · Awarded by Insightec · 2015 - 2020

Treatment of Uterine Fibroids by ExAblate MR guided FUS- Long Term Followup

ResearchPrincipal Investigator · Awarded by Insightec · 2015 - 2020

The Impact of Chronic Endometritis on IVF Pregnancy and Miscarriage Rates

ResearchPrincipal Investigator · Awarded by Vivere Heatlh LLC · 2015 - 2019

Treatment of Uterine Fibroids by ExAblate MR guided FUS

ResearchPrincipal Investigator · Awarded by Insightec · 2014 - 2018

Pilot Project: Effects of Cannabis on the Epigenome of Humans and Rats

ResearchCo Investigator · Awarded by John Templeton Foundation · 2016 - 2017

The role of progesterone in early embryo metabolism and development in the Rhesus primate (Macaca mulatta).

FellowshipPrincipal Investigator · Awarded by Foundation For The Assessment and Enhancement of Embryonic Competence · 2014 - 2017

Cardiac Effects of a Mitochondrial Progesterone Receptor

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2008 - 2010

Modulation of mitochondrial calcium by a novel progesterone receptor

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2006 - 2008

Effectiveness and Efficiency of Assisted Reproductive Technology

ResearchInvestigator · Awarded by Agency for Healthcare Research and Quality · 2005 - 2008

Fellowships, Gifts, and Supported Research


Susan Fiery Hughes Memorial Research Foundation · 2003 Duke
Charles Hammond, MD Research Foundation · 2007 Duke
Estrogen Regulation of Lipoprotein Lipase · 1996 American Health Assistance Foundation
Molecular mechanisms of dietary fatty acids on breast cancer growth and development · 1997 Department of Defense
Stress, Estrogen, Opioids and Atherogenesis in Women · 1998 Investigator · NIH
Susan Fiery Hughes Memorial Research Foundation · 2003 Duke
Charles Hammond, MD Research Foundation · 2007 Duke
Estrogen Regulation of Lipoprotein Lipase · 1996 American Health Assistance Foundation
Molecular mechanisms of dietary fatty acids on breast cancer growth and development · 1997 Department of Defense
Stress, Estrogen, Opioids and Atherogenesis in Women · 1998 Investigator · NIH
Oral vs sublingual estradiol for the prevention of migraine headaches · 1999 Mentor · ACOG
Society Gynecological Investigation Medical/Graduate Student Award · 2000 Mentor · SGI
Characterization of a new progesterone receptor in human breast cancer · 2000 Pardee Foundation
Development and use of a CD-ROM program to enhance resident learning of surgical skills in an animal lab instructional setting · 2000 Mentor · APGO-Solvay Pharmaceuticals Educational Scholarship
Regulation of Calcium Flux by Two Novel Membrane- Bound Progesterone Receptors · 2001 Mid-Atlantic American Heart Association
Endocrinology & Metabolism Training Grant · 2004 NIDDK-2T32-DK-007012-26A1
Evaluation of Tissue Distribution of a Novel Progesterone Receptor in the PRKO Mouse with Immunohistochemistry · 2004 Society Gynecological Investigation
Effectiveness and efficiency of Advanced Reproductive Technologies · 2005 Agency of Health Care and Policy
Endocrinology & Metabolism Training Grant · 2007 Mentor · NIDDK-2T32-DK-007012-26A1
Modulation of mitochondrial calcium by a novel progesterone receptor · 2006 NIH
Cardiac Effects of a Mitochondrial Progesterone Receptor · 2008 NIH
The Role of a Mitochondrial Progesterone Receptor in the Growth of Breast Epithelial Cells · 2008 Department of Defense
Adiana EASE Trial · 2004 Hologic
Molecular markers of human sperm function · 2012 NIH
Effects of male obesity, estrogen levels and endocrine disruptors on the epigenetic reprogramming in male gametes. · 2012 Duke University Nicholas School of the Environment
Determination of gene changes by progesterone action via a novel mitochondrial progesterone receptor. · 2012 Duke SOM
Comparing Focused Ultrasound and Uterine Artery Embolization for Uterine Fibroids. · 2014 NIH
A Clinical Study to Evaluate Safety of the ExAblate Model 2100, Type 1.1 System in the Treatment of Symptomatic Uterine Fibroids · 2014 Insightec
The role of progesterone in early embryo metabolism and development in the Rhesus primate (Macaca mulatta). · 2014 Mentor · Foundation for the Assessment and Enhancement of Embryonic Competence
Endocrinology and Metabolism Training Program · 2014 NIH
The role of progesterone in preimplantation human embryo metabolism · 2019 - 2021 Foundation for the Assessment and Enhancement of Embryonic Competence · $15,000.00
The Impact of Chronic Endometritis on IVF Pregnancy and Pregnancy Loss Rates · 2015 Mentor · Vivere Health Systems
Functional studies of myometrial activity with a human mutation of a T-type calcium channel protein (Cav3.1 or CACNA1G) · 2016 Bayer Pharmaceutical
Student Travel Award · 2000 Mentor · Endocrine Society