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Tracy Lynn Setji

Associate Professor of Medicine
Medicine, Endocrinology, Metabolism, and Nutrition
Duke Box 3222, Durham, NC 27710
201 Trent Dr, Baker House Room 305, DUMC Box 3222, Durham, NC 27710

Selected Publications


Evaluation of the Efficacy of a Hypoglycemia Protocol to Treat Severe Hypoglycemia.

Journal Article Clin Nurse Spec · July 2022 PURPOSE: The purpose of this quality improvement project was to evaluate the efficacy of the facility's Hypoglycemia Protocol when treating severe hypoglycemia (defined as blood glucose < 50 mg/dL). DESCRIPTION: The diabetes clinical nurse specialists cond ... Full text Link to item Cite

Duke University Medical Center Perioperative Diabetes Management Program.

Journal Article Clin Diabetes · April 2021 Quality Improvement Success Stories are published by the American Diabetes Association in collaboration with the American College of Physicians and the National Diabetes Education Program. This series is intended to highlight best practices and strategies ... Full text Link to item Cite

Evaluation of the Efficacy and Safety of an eGlycemic Management System in a Community Hospital Setting.

Journal Article J Diabetes Sci Technol · March 2021 BACKGROUND: Glucommander is an eGlycemic management system (eGMS) for intravenous (IV) and subcutaneous (SQ) insulin therapy in hospitalized patients. The purpose of this study was to evaluate the efficacy and safety of Glucommander compared to previously ... Full text Link to item Cite

Development and Implementation of a Perioperative Blood Glucose Monitoring Protocol for Patients Undergoing Spinal Surgery.

Journal Article J Perianesth Nurs · April 2020 PURPOSE: Stress-induced hyperglycemia during the perioperative period is associated with adverse outcomes after spinal surgery, which increases both patient-related burden and hospital costs. This quality improvement project describes the development and i ... Full text Link to item Cite

THE EFFECTS OF PERIOPERATIVE DEXAMETHASONE ON GLYCEMIC CONTROL AND POSTOPERATIVE OUTCOMES.

Journal Article Endocr Pract · February 2020 Objective: Perioperative glucocorticoids are commonly given to reduce pain and nausea in patients undergoing surgery. However, the glycemic effects of steroids and the potential effects on morbidity and mortality have not been systematically evaluated. Thi ... Full text Link to item Cite

DIFFERENCES IN ACHIEVING HBA1C GOALS AMONG PATIENTS SEEN BY ENDOCRINOLOGISTS AND PRIMARY CARE PROVIDERS.

Journal Article Endocr Pract · May 2019 Objective: This study evaluated whether there is a difference in the proportion of patients with type 2 diabetes who achieve a hemoglobin A1c (HbA1c) <7% within one year following treatment by an endocrinologist or primary care physician (PCP). Methods: We ... Full text Link to item Cite

Effect of A1C and Glucose on Postoperative Mortality in Noncardiac and Cardiac Surgeries.

Conference Diabetes Care · April 2018 OBJECTIVE: Hemoglobin A1c (A1C) is used in assessment of patients for elective surgeries because hyperglycemia increases risk of adverse events. However, the interplay of A1C, glucose, and surgical outcomes remains unclarified, with often only two of these ... Full text Link to item Cite

A Perioperative Medicine Model for Population Health: An Integrated Approach for an Evolving Clinical Science.

Journal Article Anesth Analg · February 2018 Health care delivery in the United States continues to balance on the tight rope that connects its transition from volume to value. Value in economic terms can be defined as the amount something exceeds its commodity price and is determined by extraordinar ... Full text Link to item Cite

Assessing the Impact of an Order Panel Utilizing Weight-Based Insulin and Standardized Monitoring of Blood Glucose for Patients With Hyperkalemia.

Journal Article Am J Med Qual · 2018 Intravenous insulin with glucose is used in urgent treatment for hyperkalemia but has a significant risk of hypoglycemia. The authors developed an order panel within the electronic health record system that utilizes weight-based insulin dosing and standard ... Full text Link to item Cite

Effects of exercise training alone vs a combined exercise and nutritional lifestyle intervention on glucose homeostasis in prediabetic individuals: a randomised controlled trial.

Journal Article Diabetologia · October 2016 AIMS/HYPOTHESIS: Although the Diabetes Prevention Program (DPP) established lifestyle changes (diet, exercise and weight loss) as the 'gold standard' preventive therapy for diabetes, the relative contribution of exercise alone to the overall utility of the ... Full text Link to item Cite

Technosphere insulin: inhaled prandial insulin.

Journal Article Expert Opin Biol Ther · 2016 INTRODUCTION: Insulin therapy is a mainstay for treatment of diabetes mellitus; however, many barriers to insulin exist. Insulin human inhalation powder (technosphere insulin) is a new FDA-approved alternative to subcutaneous bolus insulin. AREAS COVERED: ... Full text Link to item Cite

Patient Self-Management of Diabetes Care in the Inpatient Setting: Pro.

Journal Article J Diabetes Sci Technol · June 19, 2015 Patients should be allowed to manage their diabetes in the hospital. Diabetes mellitus is a common and sometimes difficult to control medical issue in hospitalized patients. Oftentimes patients who have been controlling their diabetes well as an outpatient ... Full text Link to item Cite

Managing hyperglycemia and diabetes in patients receiving enteral feedings: A health system approach.

Journal Article Hosp Pract (1995) · 2015 Evidence of poor outcomes in hospitalized patients with hyperglycemia has led to new and revised guidelines for inpatient management of diabetes. As providers become more aware of the need for better blood glucose control, they are finding limited guidance ... Full text Link to item Cite

Screening for glucose intolerance in polycystic ovary syndrome: hemoglobin A1C, fasting blood glucose or oral glucose tolerance test?

Journal Article Expert Rev Endocrinol Metab · November 2014 Polycystic ovary syndrome (PCOS) is a chronic condition with many reproductive, metabolic and psychological manifestations. Insulin resistance puts women with PCOS at an increased risk for developing impaired glucose tolerance (IGT) and diabetes (T2D). An ... Full text Link to item Cite

Review of nonalcoholic fatty liver disease in women with polycystic ovary syndrome.

Journal Article World J Gastroenterol · October 21, 2014 Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive-aged women. Women with PCOS frequently have metabolic complications including insulin resistance (IR), early diabetes, hypertension and dyslipidemia. Recent studies have ... Full text Link to item Cite

Polycystic ovary syndrome: update on diagnosis and treatment.

Journal Article Am J Med · October 2014 Polycystic ovary syndrome is now a well-recognized condition affecting 6%-25% of reproductive-aged women, depending on the definition. Over the past 3 decades, research has launched it from relative medical obscurity to a condition increasingly recognized ... Full text Link to item Cite

Albiglutide: Clinical overview of a long-acting GLP-1 receptor agonist in the treatment of Type 2 diabetes

Journal Article Expert Review of Endocrinology and Metabolism · May 1, 2013 Glucagon-like peptide-1 receptor agonists have become an important therapeutic option for patients with Type 2 diabetes because of their ability to lower blood glucose and help patients lose weight. There are currently three glucagon-like peptide-1 recepto ... Full text Cite

Higher high-density lipoprotein cholesterol in African-American women with polycystic ovary syndrome compared with Caucasian counterparts.

Journal Article J Clin Endocrinol Metab · September 2010 CONTEXT: Studies have demonstrated lipid differences among African-Americans and Caucasians and between women with polycystic ovary syndrome (PCOS) and normally ovulating women. However, few studies have examined racial differences in lipoprotein levels in ... Full text Link to item Cite

Effects of exercise on lipoprotein particles in women with polycystic ovary syndrome.

Journal Article Med Sci Sports Exerc · March 2009 PURPOSE: Women with polycystic ovary syndrome (PCOS) commonly have insulin resistance. Insulin resistance is associated with marked abnormalities of lipoprotein size and subclass particle concentration. The purpose of this study was to examine the effects ... Full text Link to item Cite

Comprehensive clinical management of polycystic ovary syndrome.

Journal Article Minerva Med · June 2007 Polycystic ovary syndrome (PCOS) affects 6-7% of reproductive-aged women. Although the diagnostic criteria for PCOS have been debated, it is frequently characterized by hyperandrogenism (hirsutism, acne, male-pattern hair loss), oligo-anovulation, and poly ... Link to item Cite

Polycystic ovary syndrome: diagnosis and treatment.

Journal Article Am J Med · February 2007 Polycystic ovary syndrome affects 6%-7% of reproductive-aged women, making it the most common endocrine disorder in this population. It is characterized by chronic anovulation and hyperandrogenism. Affected women may present with reproductive manifestation ... Full text Link to item Cite

Nonalcoholic steatohepatitis and nonalcoholic Fatty liver disease in young women with polycystic ovary syndrome.

Journal Article J Clin Endocrinol Metab · May 2006 CONTEXT: Nonalcoholic fatty liver disease and polycystic ovary syndrome (PCOS) are both associated with insulin resistance. Thus, women with PCOS may have an increased prevalence of nonalcoholic fatty liver disease, including nonalcoholic steatohepatitis ( ... Full text Link to item Cite

Visual vignette

Journal Article Endocrine Practice · May 1, 2006 Cite

Polycystic ovary syndrome and severe nonalcoholic steatohepatitis: beneficial effect of modest weight loss and exercise on liver biopsy findings.

Journal Article Endocr Pract · 2005 OBJECTIVE: To report a case of biopsy-documented nonalcoholic steatohepatitis (NASH), which improved appreciably through moderate exercise and weight loss in a young woman with polycystic ovary syndrome (PCOS) and insulin resistance. METHODS: We present a ... Full text Link to item Cite

Gestational diabetes mellitus

Journal Article Clinical Diabetes · January 1, 2005 Full text Cite