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A leave-one-out cross-validation SAS macro for the identification of markers associated with survival.

Publication ,  Journal Article
Rushing, C; Bulusu, A; Hurwitz, HI; Nixon, AB; Pang, H
Published in: Comput Biol Med
February 2015

A proper internal validation is necessary for the development of a reliable and reproducible prognostic model for external validation. Variable selection is an important step for building prognostic models. However, not many existing approaches couple the ability to specify the number of covariates in the model with a cross-validation algorithm. We describe a user-friendly SAS macro that implements a score selection method and a leave-one-out cross-validation approach. We discuss the method and applications behind this algorithm, as well as details of the SAS macro.

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Published In

Comput Biol Med

DOI

EISSN

1879-0534

Publication Date

February 2015

Volume

57

Start / End Page

123 / 129

Location

United States

Related Subject Headings

  • Survival Analysis
  • Reproducibility of Results
  • Prognosis
  • Humans
  • Computer Simulation
  • Computational Biology
  • Clinical Trials as Topic
  • Biomedical Engineering
  • Biomarkers
  • Algorithms
 

Citation

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ICMJE
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Rushing, C., Bulusu, A., Hurwitz, H. I., Nixon, A. B., & Pang, H. (2015). A leave-one-out cross-validation SAS macro for the identification of markers associated with survival. Comput Biol Med, 57, 123–129. https://doi.org/10.1016/j.compbiomed.2014.11.015
Rushing, Christel, Anuradha Bulusu, Herbert I. Hurwitz, Andrew B. Nixon, and Herbert Pang. “A leave-one-out cross-validation SAS macro for the identification of markers associated with survival.Comput Biol Med 57 (February 2015): 123–29. https://doi.org/10.1016/j.compbiomed.2014.11.015.
Rushing C, Bulusu A, Hurwitz HI, Nixon AB, Pang H. A leave-one-out cross-validation SAS macro for the identification of markers associated with survival. Comput Biol Med. 2015 Feb;57:123–9.
Rushing, Christel, et al. “A leave-one-out cross-validation SAS macro for the identification of markers associated with survival.Comput Biol Med, vol. 57, Feb. 2015, pp. 123–29. Pubmed, doi:10.1016/j.compbiomed.2014.11.015.
Rushing C, Bulusu A, Hurwitz HI, Nixon AB, Pang H. A leave-one-out cross-validation SAS macro for the identification of markers associated with survival. Comput Biol Med. 2015 Feb;57:123–129.
Journal cover image

Published In

Comput Biol Med

DOI

EISSN

1879-0534

Publication Date

February 2015

Volume

57

Start / End Page

123 / 129

Location

United States

Related Subject Headings

  • Survival Analysis
  • Reproducibility of Results
  • Prognosis
  • Humans
  • Computer Simulation
  • Computational Biology
  • Clinical Trials as Topic
  • Biomedical Engineering
  • Biomarkers
  • Algorithms