Skip to main content
Journal cover image

Social cognitive training in adolescents with chromosome 22q11.2 deletion syndrome: feasibility and preliminary effects of the intervention.

Publication ,  Journal Article
Shashi, V; Harrell, W; Eack, S; Sanders, C; McConkie-Rosell, A; Keshavan, MS; Bonner, MJ; Schoch, K; Hooper, SR
Published in: J Intellect Disabil Res
October 2015

BACKGROUND: Children with chromosome 22q11.2 deletion syndrome (22q11DS) often have deficits in social cognition and social skills that contribute to poor adaptive functioning. These deficits may be of relevance to the later occurrence of serious psychiatric illnesses such as schizophrenia. Yet, there are no evidence-based interventions to improve social cognitive functioning in children with 22q11DS. METHODS: Using a customised social cognitive curriculum, we conducted a pilot small-group-based social cognitive training (SCT) programme in 13 adolescents with 22q11DS, relative to a control group of nine age- and gender-matched adolescents with 22q11DS. RESULTS: We found the SCT programme to be feasible, with high rates of compliance and satisfaction on the part of the participants and their families. Our preliminary analyses indicated that the intervention group showed significant improvements in an overall social cognitive composite index. CONCLUSIONS: SCT in a small-group format for adolescents with 22q11DS is feasible and results in gains in social cognition. A larger randomised controlled trial would permit assessment of efficacy of this promising novel intervention.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

J Intellect Disabil Res

DOI

EISSN

1365-2788

Publication Date

October 2015

Volume

59

Issue

10

Start / End Page

902 / 913

Location

England

Related Subject Headings

  • Treatment Outcome
  • Social Skills
  • Social Perception
  • Rehabilitation
  • Pilot Projects
  • Male
  • Humans
  • Female
  • Feasibility Studies
  • DiGeorge Syndrome
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Shashi, V., Harrell, W., Eack, S., Sanders, C., McConkie-Rosell, A., Keshavan, M. S., … Hooper, S. R. (2015). Social cognitive training in adolescents with chromosome 22q11.2 deletion syndrome: feasibility and preliminary effects of the intervention. J Intellect Disabil Res, 59(10), 902–913. https://doi.org/10.1111/jir.12192
Shashi, V., W. Harrell, S. Eack, C. Sanders, A. McConkie-Rosell, M. S. Keshavan, M. J. Bonner, K. Schoch, and S. R. Hooper. “Social cognitive training in adolescents with chromosome 22q11.2 deletion syndrome: feasibility and preliminary effects of the intervention.J Intellect Disabil Res 59, no. 10 (October 2015): 902–13. https://doi.org/10.1111/jir.12192.
Shashi V, Harrell W, Eack S, Sanders C, McConkie-Rosell A, Keshavan MS, et al. Social cognitive training in adolescents with chromosome 22q11.2 deletion syndrome: feasibility and preliminary effects of the intervention. J Intellect Disabil Res. 2015 Oct;59(10):902–13.
Shashi, V., et al. “Social cognitive training in adolescents with chromosome 22q11.2 deletion syndrome: feasibility and preliminary effects of the intervention.J Intellect Disabil Res, vol. 59, no. 10, Oct. 2015, pp. 902–13. Pubmed, doi:10.1111/jir.12192.
Shashi V, Harrell W, Eack S, Sanders C, McConkie-Rosell A, Keshavan MS, Bonner MJ, Schoch K, Hooper SR. Social cognitive training in adolescents with chromosome 22q11.2 deletion syndrome: feasibility and preliminary effects of the intervention. J Intellect Disabil Res. 2015 Oct;59(10):902–913.
Journal cover image

Published In

J Intellect Disabil Res

DOI

EISSN

1365-2788

Publication Date

October 2015

Volume

59

Issue

10

Start / End Page

902 / 913

Location

England

Related Subject Headings

  • Treatment Outcome
  • Social Skills
  • Social Perception
  • Rehabilitation
  • Pilot Projects
  • Male
  • Humans
  • Female
  • Feasibility Studies
  • DiGeorge Syndrome