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Paediatric cardiovascular clinical trials: an analysis of ClinicalTrials.gov and the Food and Drug Administration Pediatric Drug Labeling Database.

Publication ,  Conference
Hill, KD; Henderson, HT; Hornik, CP; Li, JS
Published in: Cardiol Young
August 2015

Recent regulatory initiatives in the United States of America and Europe have transformed the paediatric clinical trials landscape by significantly increasing capital investment and paediatric trial volume. The purpose of this manuscript was to review the impact of these initiatives on the paediatric cardiovascular trials landscape when compared with other paediatric sub-specialties. We also evaluate factors that may have contributed to the success or failure of recent major paediatric cardiovascular trials so as to inform the optimal design and conduct of future trials in the field.

Duke Scholars

Published In

Cardiol Young

DOI

EISSN

1467-1107

Publication Date

August 2015

Volume

25 Suppl 2

Issue

0 2

Start / End Page

172 / 180

Location

England

Related Subject Headings

  • United States Food and Drug Administration
  • United States
  • Pediatrics
  • Humans
  • Europe
  • Drug Labeling
  • Databases, Factual
  • Clinical Trials as Topic
  • Cardiovascular System & Hematology
  • Cardiovascular Diseases
 

Citation

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ICMJE
MLA
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Hill, K. D., Henderson, H. T., Hornik, C. P., & Li, J. S. (2015). Paediatric cardiovascular clinical trials: an analysis of ClinicalTrials.gov and the Food and Drug Administration Pediatric Drug Labeling Database. In Cardiol Young (Vol. 25 Suppl 2, pp. 172–180). England. https://doi.org/10.1017/S1047951115000980
Hill, Kevin D., Heather T. Henderson, Christoph P. Hornik, and Jennifer S. Li. “Paediatric cardiovascular clinical trials: an analysis of ClinicalTrials.gov and the Food and Drug Administration Pediatric Drug Labeling Database.” In Cardiol Young, 25 Suppl 2:172–80, 2015. https://doi.org/10.1017/S1047951115000980.
Hill, Kevin D., et al. “Paediatric cardiovascular clinical trials: an analysis of ClinicalTrials.gov and the Food and Drug Administration Pediatric Drug Labeling Database.Cardiol Young, vol. 25 Suppl 2, no. 0 2, 2015, pp. 172–80. Pubmed, doi:10.1017/S1047951115000980.
Journal cover image

Published In

Cardiol Young

DOI

EISSN

1467-1107

Publication Date

August 2015

Volume

25 Suppl 2

Issue

0 2

Start / End Page

172 / 180

Location

England

Related Subject Headings

  • United States Food and Drug Administration
  • United States
  • Pediatrics
  • Humans
  • Europe
  • Drug Labeling
  • Databases, Factual
  • Clinical Trials as Topic
  • Cardiovascular System & Hematology
  • Cardiovascular Diseases