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Application of Whole-Genome Sequencing to an Unusual Outbreak of Invasive Group A Streptococcal Disease.

Publication ,  Journal Article
Galloway-Peña, J; Clement, ME; Sharma Kuinkel, BK; Ruffin, F; Flores, AR; Levinson, H; Shelburne, SA; Moore, Z; Fowler, VG
Published in: Open Forum Infect Dis
January 2016

Whole-genome analysis was applied to investigate atypical point-source transmission of 2 invasive group A streptococcal (GAS) infections. Isolates were serotype M4, ST39, and genetically indistinguishable. Comparison with MGAS10750 revealed nonsynonymous polymorphisms in ropB and increased speB transcription. This study demonstrates the usefulness of whole-genome analyses for GAS outbreaks.

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Published In

Open Forum Infect Dis

DOI

ISSN

2328-8957

Publication Date

January 2016

Volume

3

Issue

1

Start / End Page

ofw042

Location

United States

Related Subject Headings

  • 3207 Medical microbiology
  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
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Galloway-Peña, J., Clement, M. E., Sharma Kuinkel, B. K., Ruffin, F., Flores, A. R., Levinson, H., … Fowler, V. G. (2016). Application of Whole-Genome Sequencing to an Unusual Outbreak of Invasive Group A Streptococcal Disease. Open Forum Infect Dis, 3(1), ofw042. https://doi.org/10.1093/ofid/ofw042
Galloway-Peña, Jessica, Meredith E. Clement, Batu K. Sharma Kuinkel, Felicia Ruffin, Anthony R. Flores, Howard Levinson, Samuel A. Shelburne, Zack Moore, and Vance G. Fowler. “Application of Whole-Genome Sequencing to an Unusual Outbreak of Invasive Group A Streptococcal Disease.Open Forum Infect Dis 3, no. 1 (January 2016): ofw042. https://doi.org/10.1093/ofid/ofw042.
Galloway-Peña J, Clement ME, Sharma Kuinkel BK, Ruffin F, Flores AR, Levinson H, et al. Application of Whole-Genome Sequencing to an Unusual Outbreak of Invasive Group A Streptococcal Disease. Open Forum Infect Dis. 2016 Jan;3(1):ofw042.
Galloway-Peña, Jessica, et al. “Application of Whole-Genome Sequencing to an Unusual Outbreak of Invasive Group A Streptococcal Disease.Open Forum Infect Dis, vol. 3, no. 1, Jan. 2016, p. ofw042. Pubmed, doi:10.1093/ofid/ofw042.
Galloway-Peña J, Clement ME, Sharma Kuinkel BK, Ruffin F, Flores AR, Levinson H, Shelburne SA, Moore Z, Fowler VG. Application of Whole-Genome Sequencing to an Unusual Outbreak of Invasive Group A Streptococcal Disease. Open Forum Infect Dis. 2016 Jan;3(1):ofw042.
Journal cover image

Published In

Open Forum Infect Dis

DOI

ISSN

2328-8957

Publication Date

January 2016

Volume

3

Issue

1

Start / End Page

ofw042

Location

United States

Related Subject Headings

  • 3207 Medical microbiology
  • 3202 Clinical sciences