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Major review: Exfoliation syndrome; advances in disease genetics, molecular biology, and epidemiology.

Publication ,  Journal Article
Aboobakar, IF; Johnson, WM; Stamer, WD; Hauser, MA; Allingham, RR
Published in: Exp Eye Res
January 2017

Exfoliation syndrome (XFS) is a common age-related disorder that leads to deposition of extracellular fibrillar material throughout the body. The most recognized disease manifestation is exfoliation glaucoma (XFG), which is a common cause of blindness worldwide. Recent developments in XFS genetics, cell biology and epidemiology have greatly improved our understanding of the etiology of this complex inherited disease. This review summarizes current knowledge of XFS pathogenesis, identifies gaps in knowledge, and discusses areas for future research.

Duke Scholars

Published In

Exp Eye Res

DOI

EISSN

1096-0007

Publication Date

January 2017

Volume

154

Start / End Page

88 / 103

Location

England

Related Subject Headings

  • Transforming Growth Factor beta1
  • Polymorphism, Genetic
  • Ophthalmology & Optometry
  • Morbidity
  • Molecular Biology
  • Humans
  • Homocysteine
  • Global Health
  • Genetic Markers
  • Exfoliation Syndrome
 

Citation

APA
Chicago
ICMJE
MLA
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Aboobakar, I. F., Johnson, W. M., Stamer, W. D., Hauser, M. A., & Allingham, R. R. (2017). Major review: Exfoliation syndrome; advances in disease genetics, molecular biology, and epidemiology. Exp Eye Res, 154, 88–103. https://doi.org/10.1016/j.exer.2016.11.011
Aboobakar, Inas F., William M. Johnson, W Daniel Stamer, Michael A. Hauser, and R Rand Allingham. “Major review: Exfoliation syndrome; advances in disease genetics, molecular biology, and epidemiology.Exp Eye Res 154 (January 2017): 88–103. https://doi.org/10.1016/j.exer.2016.11.011.
Aboobakar IF, Johnson WM, Stamer WD, Hauser MA, Allingham RR. Major review: Exfoliation syndrome; advances in disease genetics, molecular biology, and epidemiology. Exp Eye Res. 2017 Jan;154:88–103.
Aboobakar, Inas F., et al. “Major review: Exfoliation syndrome; advances in disease genetics, molecular biology, and epidemiology.Exp Eye Res, vol. 154, Jan. 2017, pp. 88–103. Pubmed, doi:10.1016/j.exer.2016.11.011.
Aboobakar IF, Johnson WM, Stamer WD, Hauser MA, Allingham RR. Major review: Exfoliation syndrome; advances in disease genetics, molecular biology, and epidemiology. Exp Eye Res. 2017 Jan;154:88–103.
Journal cover image

Published In

Exp Eye Res

DOI

EISSN

1096-0007

Publication Date

January 2017

Volume

154

Start / End Page

88 / 103

Location

England

Related Subject Headings

  • Transforming Growth Factor beta1
  • Polymorphism, Genetic
  • Ophthalmology & Optometry
  • Morbidity
  • Molecular Biology
  • Humans
  • Homocysteine
  • Global Health
  • Genetic Markers
  • Exfoliation Syndrome