Regulation of inflammation by β-arrestins: Not just receptor tales.
Publication
, Journal Article
Freedman, NJ; Shenoy, SK
Published in: Cell Signal
January 2018
The ubiquitously expressed, multifunctional scaffolding proteins β-arrestin1 and β-arrestin2 each affect inflammatory signaling in a variety of cell lines. In addition to binding the carboxyl-terminal tails of innumerable 7-transmembrane receptors, β-arrestins scaffold untold numbers of other plasma membrane and cytoplasmic proteins. Consequently, the effects of β-arrestins on inflammatory signaling are diverse, and context-specific. This review highlights the roles of β-arrestins in regulating canonical activation of the pro-inflammatory transcription factor NFκB.
Duke Scholars
Published In
Cell Signal
DOI
EISSN
1873-3913
Publication Date
January 2018
Volume
41
Start / End Page
41 / 45
Location
England
Related Subject Headings
- beta-Arrestins
- Ubiquitination
- Transfection
- NF-kappa B
- Mice, Knockout
- Mice
- Inflammation
- Humans
- Cell Line
- Biochemistry & Molecular Biology
Citation
APA
Chicago
ICMJE
MLA
NLM
Freedman, N. J., & Shenoy, S. K. (2018). Regulation of inflammation by β-arrestins: Not just receptor tales. Cell Signal, 41, 41–45. https://doi.org/10.1016/j.cellsig.2017.02.008
Freedman, Neil J., and Sudha K. Shenoy. “Regulation of inflammation by β-arrestins: Not just receptor tales.” Cell Signal 41 (January 2018): 41–45. https://doi.org/10.1016/j.cellsig.2017.02.008.
Freedman NJ, Shenoy SK. Regulation of inflammation by β-arrestins: Not just receptor tales. Cell Signal. 2018 Jan;41:41–5.
Freedman, Neil J., and Sudha K. Shenoy. “Regulation of inflammation by β-arrestins: Not just receptor tales.” Cell Signal, vol. 41, Jan. 2018, pp. 41–45. Pubmed, doi:10.1016/j.cellsig.2017.02.008.
Freedman NJ, Shenoy SK. Regulation of inflammation by β-arrestins: Not just receptor tales. Cell Signal. 2018 Jan;41:41–45.
Published In
Cell Signal
DOI
EISSN
1873-3913
Publication Date
January 2018
Volume
41
Start / End Page
41 / 45
Location
England
Related Subject Headings
- beta-Arrestins
- Ubiquitination
- Transfection
- NF-kappa B
- Mice, Knockout
- Mice
- Inflammation
- Humans
- Cell Line
- Biochemistry & Molecular Biology